Gender-Specific Variation in the Prognosis of Papillary Thyroid Cancer TNM Stages II to IV.

Abstract:

:To investigate the correlation between gender and the clinical presentation of papillary thyroid cancer and the long-term followup results, 435 patients who underwent total or near-total thyroidectomy were enrolled in this study. Among these papillary thyroid cancer patients, 12.2% showed lymph node metastases and a higher incidence of male patients in the N1b group. There were 65 from 316 female (20.6%) and 49 from 120 male (40.8%) patients who had a postoperative disease progression. A total of 55 (12.6%) patients died of thyroid cancer. Male patients showed a higher thyroid cancer mortality than the females. Multiple regression analysis showed that male gender was an independent risk factor for cancer recurrence and mortality. Male patients with TNM stages II to IV of papillary thyroid cancer need to adopt aggressive surgical and postoperative (131)I therapy.

journal_name

Int J Endocrinol

authors

Hsieh SH,Chen ST,Hsueh C,Chao TC,Lin JD

doi

10.1155/2012/379097

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

379097

eissn

1687-8337

issn

1687-8345

journal_volume

2012

pub_type

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