Growth retardation in children with kidney disease.

abstract：Objective:We sought to evaluate the association between femoral neck (FN) and lumbar spine (LS) bone mineral densities (BMDs) with severity of chronic kidney disease (CKD) and prevalence of osteopenia or osteoporosis (OP) among the CKD group. Methods:Cross-sectional data from 11050 participants aged ≥20 years from the...

journal_title：International journal of endocrinology

authors： Huang JF,Zheng XQ,Sun XL,Zhou X,Liu J,Li YM,Wang XY,Zhang XL,Wu AM

更新日期：2020-10-26 00:00:00

abstract：:To investigate the correlation between gender and the clinical presentation of papillary thyroid cancer and the long-term followup results, 435 patients who underwent total or near-total thyroidectomy were enrolled in this study. Among these papillary thyroid cancer patients, 12.2% showed lymph node metastases and a h...

journal_title：International journal of endocrinology

authors： Hsieh SH,Chen ST,Hsueh C,Chao TC,Lin JD

更新日期：2012-01-01 00:00:00

abstract：:Obesity is a growing problem in modern society and medicine. It closely associates with metabolic disorders such as type 2 diabetes mellitus (T2DM) and hepatic and cardiovascular diseases such as nonalcoholic fatty liver disease, atherosclerosis, myocarditis, and hypertension. Obesity is often associated with latent i...

journal_title：International journal of endocrinology

authors： Stafeev IS,Vorotnikov AV,Ratner EI,Menshikov MY,Parfyonova YV

更新日期：2017-01-01 00:00:00

abstract：Background:Aromatase inhibitors in women with breast cancer have been associated with cancer treatment-induced bone loss (CTIBL), increased fracture risk, and impairment of glucose metabolism. Denosumab (Dmab), a monoclonal antibody against RANKL, which is a key regulator of the osteoclast activity, is effective as an ...

journal_title：International journal of endocrinology

authors： Rossini A,Frigerio S,Dozio E,Trevisan R,Perseghin G,Corbetta S

更新日期：2020-11-06 00:00:00

abstract：:Gestational diabetes mellitus (GDM) is defined as any degree of carbohydrate intolerance, with onset or first recognition during second or third trimester of gestation. It is estimated that approximately 7% of all pregnancies are complicated by GDM and that its prevalence is rising all over the world. Thus, the screen...

journal_title：International journal of endocrinology

authors： Guarino E,Delli Poggi C,Grieco GE,Cenci V,Ceccarelli E,Crisci I,Sebastiani G,Dotta F

更新日期：2018-04-12 00:00:00

abstract：:The determination of B-type natriuretic peptides (BNP) may have a role in the diagnosis of heart failure (HF) or guiding HF therapy. This study investigated the role of BNP determination in a cohort of elderly patients admitted to hospital with acute decompensated HF and its correlation with main demographic, clinical...

journal_title：International journal of endocrinology

authors： Leto L,Testa M,Feola M

更新日期：2015-01-01 00:00:00

abstract：:The chemosensitivity of anaplastic thyroid cancer (ATC) to some cytotoxic agents was investigated by the histoculture drug response assay (HDRA). Thirty specimens from 22 patients with ATC were obtained from surgically resected subjects. The drugs tested were paclitaxel (PTX), docetaxel (DOC), adriamycin (ADM), nedapl...

journal_title：International journal of endocrinology

authors： Uruno T,Masaki C,Akaishi J,Matsuzu K,Suzuki A,Ohkuwa K,Shibuya H,Kitagawa W,Nagahama M,Sugino K,Ito K

更新日期：2015-01-01 00:00:00

abstract：:Point-of-care (POC) glucose technology is currently considered to be insufficiently accurate for the diagnosis of diabetes. The objective of this study was to investigate the diagnostic accuracy of an innovative, interference-resistant POC glucose meter (StatStrip glucose hospital meter, Nova Biomedical, USA) in subje...

journal_title：International journal of endocrinology

authors： Vučić Lovrenčić M,Radišić Biljak V,Božičević S,Pape-Medvidović E,Ljubić S

更新日期：2013-01-01 00:00:00

abstract：:Pancreatic beta-cells, which secrete the hormone insulin, are the key arbiters of glucose homeostasis. Defective beta-cell numbers and/or function underlie essentially all major forms of diabetes and must be restored if diabetes is to be cured. Thus, the identification of the molecular regulators of beta-cell mass and...

journal_title：International journal of endocrinology

authors： Tarabra E,Pelengaris S,Khan M

更新日期：2012-01-01 00:00:00

abstract：:Melatonin (N-acetyl-5-methoxytryptamine) is a hormone synthesized and secreted by the pineal gland mainly during the night, since light exposure suppresses its production. Initially, an implication of this indoleamine in malignant disease was described in endocrine-responsive breast cancer. Data from several clinical ...

journal_title：International journal of endocrinology

authors： Menéndez-Menéndez J,Martínez-Campa C

更新日期：2018-10-02 00:00:00

abstract：:Sestrin (SESN) is known as a cysteine sulfinic acid reductase. Recently, nonredox functions of SESN in metabolic regulation and antitumor property have been recognized. While mechanisms underlying the expression of SESN are not fully understood. Here we report that insulin markedly increased SESN2 level in HepG2 cells...

journal_title：International journal of endocrinology

authors： Chai D,Wang G,Zhou Z,Yang H,Yu Z

更新日期：2015-01-01 00:00:00

abstract：:To elucidate whether adrenergic overtone is involved in the pathophysiology of men with lifelong (LL) premature ejaculation (PE), we investigated differences in reactive hyperemia index (RHI) responses by using peripheral arterial tonometry (PAT). 20 men with LL-PE (18-40 years) were enrolled in an 8-week, double-blin...

journal_title：International journal of endocrinology

authors： Francomano D,Donini LM,Lenzi A,Aversa A

更新日期：2013-01-01 00:00:00

abstract：:We aimed to estimate the impact of ingestion of a pure protein load on the glucose levels in T1DM patients treated with insulin pumps. We examined 10 T1DM patients (6 females, mean age-32.3 years, mean HbA1c-6.8%) treated with insulin pumps equipped with a continuous glucose monitoring system (CGMS). In Phase I, basel...

journal_title：International journal of endocrinology

authors： Klupa T,Benbenek-Klupa T,Matejko B,Mrozinska S,Malecki MT

更新日期：2015-01-01 00:00:00

abstract：:The presence of brown adipose tissue (BAT) in humans is unclear. Pheochromocytomas (PHEO) are rare tumors of neuroectodermal origin which occur in 0.1-0.2% of patients with hypertension. We sought to evaluate the presence and activity of BAT surrounding adrenal PHEO in a well-studied sample of 11 patients who were dia...

journal_title：International journal of endocrinology

authors： Iacobellis G,Di Gioia C,Petramala L,Chiappetta C,Serra V,Zinnamosca L,Marinelli C,Ciardi A,De Toma G,Letizia C

更新日期：2013-01-01 00:00:00

abstract：:Stevia rebaudiana (Bert.) Bertoni besides being a source of noncaloric sweeteners is also an important source of bioactive molecules. Many plant extracts, mostly obtained with ethyl acetate solvent, are rich in polyphenol compounds that present insulinotropic effects. To investigate whether the nonsweetener fraction, ...

journal_title：International journal of endocrinology

authors： Piovan S,Pavanello A,Peixoto GML,Matiusso CCI,de Moraes AMP,Martins IP,Malta A,Palma-Rigo K,da Silva Franco CC,Milani PG,Dacome AS,da Costa SC,de Freitas Mathias PC,Mareze-Costa CE

更新日期：2018-04-29 00:00:00

abstract：:A quarter of men with obesity or type 2 diabetes have hypogonadotropic hypogonadism. Animal studies and in vitro data have shown that insulin action and insulin responsiveness in the brain are necessary for the maintenance of the functional integrity of the hypothalamo-hypophyseal-gonadal axis. We conducted a randomiz...

journal_title：International journal of endocrinology

authors： Dhindsa S,Chemitiganti R,Ghanim H,Santiago E,Haider A,Chaar N,Mok M,McKee A,Dandona P

更新日期：2018-10-31 00:00:00

abstract：:Background. Nonclassic congenital adrenal hyperplasia (NCAH), caused by mutations in the gene encoding 21-hydroxylase, is a common autosomal recessive disorder. In the present work, our aim was to determine the prevalence of NCAH presenting as premature pubarche (PP), hirsutism, or polycystic ovarian syndrome (PCOS) a...

journal_title：International journal of endocrinology

authors： Binay C,Simsek E,Cilingir O,Yuksel Z,Kutlay O,Artan S

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:We aimed to explore whether squamous cell carcinoma antigen (SCC), cytokeratin 19 fragment (Cyfra21-1), neuron-specific enolase (NSE), and carcinoembryonic antigen (CEA) are elevated in diabetic nephropathy (DN) and the association between urinary albumin-to-creatinine ratio (UACR) and tumor markers in diabet...

journal_title：International journal of endocrinology

authors： Chen J,Tao F,Zhang B,Chen Q,Qiu Y,Luo Q,Gen Y,Meng J,Zhang J,Lu H

更新日期：2017-01-01 00:00:00

abstract：:Atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) in thyroid fine needle aspiration (FNA) is a challenging category. The malignancy risk is different by multiple factors and subsequent management strategy is inconclusive. Therefore, we analyzed the malignancy risk of AUS/FLU...

journal_title：International journal of endocrinology

authors： Hong SH,Lee H,Cho MS,Lee JE,Sung YA,Hong YS

更新日期：2018-07-30 00:00:00

abstract：OBJECTIVE:Current study was designed to investigate the association of metabolic syndrome (MetS) with depression, anxiety, psychological distress, and quality of life (QoL). DESIGN:Two hundred and fifteen contributors with MetS and 253 participants without MetS were randomly selected from 2151 participants of Isfahan ...

journal_title：International journal of endocrinology

authors： Roohafza H,Sadeghi M,Talaei M,Pourmoghaddas Z,Sarrafzadegan N

更新日期：2012-01-01 00:00:00

abstract：:Whether serum magnesium deficiency is independently associated with the prevalence of microalbuminuria is still unclear. The objective of the present study was to elucidate the association between serum magnesium and microalbuminuria in diabetic patients. A cross-sectional study was conducted in 1829 diabetic subjects...

journal_title：International journal of endocrinology

authors： Xu B,Sun J,Deng X,Huang X,Sun W,Xu Y,Xu M,Lu J,Bi Y

更新日期：2013-01-01 00:00:00

abstract：:Background. The purpose of the present study was to assess the feasibility of using miR-126 in the urine as a biomarker for diabetic nephropathy. Methods. miRNAs were extracted from the urine samples of T2DM patients with diabetic nephropathy (DN; n = 92), T2DM without DN (n = 86), and 85 healthy volunteers using quan...

journal_title：International journal of endocrinology

authors： Liu Y,Gao G,Yang C,Zhou K,Shen B,Liang H,Jiang X

更新日期：2014-01-01 00:00:00

abstract：Background:Type 2 diabetes mellitus is a serious public health problem worldwide. Accumulating evidence has shown that β-cell dysfunction is an important mechanism underlying diabetes mellitus. The changes in the physiological state of islet stellate cells (ISCs) and the effects of these cells on β-cell dysfunction is ...

journal_title：International journal of endocrinology

authors： Xu W,Jones PM,Geng H,Li R,Liu X,Li Y,Lv Q,Liu Y,Wang J,Wang X,Sun Z,Liang J

更新日期：2020-02-24 00:00:00

abstract：Objectives:To compare the predictive ability of six anthropometric indices for identification of metabolic syndrome (MetS) and to determine their optimal cut-off points among Chinese adults. Methods:A total of 59,029 participants were enrolled. Body mass index (BMI), waist circumference (WC), waist-to-height ratio (WH...

journal_title：International journal of endocrinology

authors： Zhang J,Zhu W,Qiu L,Huang L,Fang L

更新日期：2018-09-17 00:00:00

abstract：:Background. Reduced testicular volume (TV) (<12 cm(3)) is associated with lower testicular function. Several studies explored the conventional sperm parameters (concentration, motility, and morphology) and the endocrine function (gonadotropins and testosterone serum concentrations) in the patients with reduction of TV...

journal_title：International journal of endocrinology

authors： Condorelli R,Calogero AE,La Vignera S

更新日期：2013-01-01 00:00:00

abstract：:X-linked Adrenal Hypoplasia Congenita (AHC) is caused by deletions or point mutations in the NR0B1 (DAX1) gene. We present a boy with AHC who came at the age of 25 days in a severe state due to prolonged vomiting and progressive dehydration. Laboratory studies showed prominent hyponatremia and hyperkaliemia but not hy...

journal_title：International journal of endocrinology

authors： Rojek A,Krawczynski MR,Jamsheer A,Sowinska-Seidler A,Iwaniszewska B,Malunowicz E,Niedziela M

更新日期：2016-01-01 00:00:00

abstract：:Objective. The follow-up of GH levels in short-stature children with pituitary hyperplasia secondary to primary hypothyroidism (PPH) is reported in a few cases. We aimed to observe changes in GH secretion in short-stature children with PPH. Methods. A total of 11 short-stature children with PPH accompanied by low GH l...

journal_title：International journal of endocrinology

authors： Liu M,Hu Y,Li G,Hu W

更新日期：2015-01-01 00:00:00

abstract：:In the last decade, miRNAs have received substantial attention as potential players of diabetes microvascular complications, affecting the kidney, the retina, and the peripheral neurons. Compelling evidence indicates that abnormally expressed miRNAs have pivotal roles in key pathogenic processes of microvascular compl...

journal_title：International journal of endocrinology

authors： Barutta F,Bellini S,Mastrocola R,Bruno G,Gruden G

更新日期：2018-03-07 00:00:00

abstract：:Purpose. To evaluate the associations between metformin, insulin, statins, and levothyroxine and breast cancer characteristics and outcome. Methods. Retrospective chart review of patients treated in our institute for early estrogen receptor (ER) positive, human epidermal growth factor receptor 2 negative breast cancer...

journal_title：International journal of endocrinology

authors： Goldvaser H,Rizel S,Hendler D,Neiman V,Shepshelovich D,Shochat T,Sulkes A,Brenner B,Yerushalmi R

更新日期：2016-01-01 00:00:00

abstract：:Plasma FGF-23 concentrations and its relationship with calcium-phosphate homeostasis were evaluated in 48 perimenopausal obese women and in 29 nonobese controls. Serum parathyroid hormone, 25-hydroxyvitamin D(3), CTX1, osteocalcin, total calcium, phosphorus, creatinine, and plasma intact FGF-23 concentrations were ass...

journal_title：International journal of endocrinology

authors： Holecki M,Chudek J,Więcek A,Titz-Bober M,Duława J

更新日期：2011-01-01 00:00:00