Sperm proteomics: road to male fertility and contraception.

abstract：:Introduction. Differentiated thyroid cancer treatment usually consists of thyroidectomy and radio ablation in hypothyroidism 4-6 weeks after surgery. Replacing hypothyroidism by recombinant human thyroid stimulating hormone can facilitate radio ablation in euthyroidism within one week after surgery. The outcome of thi...

journal_title：International journal of endocrinology

authors： Emmanouilidis N,Schrem H,Winkler M,Klempnauer J,Scheumann GF

更新日期：2013-01-01 00:00:00

abstract：:The complementary role of hyperglycemia and p27(kip1) suppression on islet beta cell regeneration was investigated in a syngeneic mouse model. p27(kip1) gene silencing was performed by infecting islets of C57BL/6 with shRNA lentiviral particles. At 54 hours after viral infection, p27(kip1) protein content in cultured ...

journal_title：International journal of endocrinology

authors： Chen ST,Fu SH,Hsu S,Huang YY,Hsu BR

更新日期：2012-01-01 00:00:00

abstract：:Aims. To evaluate the predictive power of pretransplant HbA1c for new-onset diabetes after transplantation (NODAT) in kidney transplant candidates, who had several predispositions for fluctuated HbA1c levels. Methods. We performed a retrospective study of 119 patients without diabetes who received kidney transplantati...

journal_title：International journal of endocrinology

authors： Tokodai K,Amada N,Haga I,Nakamura A,Kashiwadate T,Kawagishi N,Ohuchi N

更新日期：2014-01-01 00:00:00

abstract：:The study explored the utility of four-point preprandial glucose self-monitoring to calculate several indices of glycemic control and variability in a study adding the DPP-4 inhibitor vildagliptin to ongoing insulin therapy. This analysis utilized data from a double-blind, randomized, placebo-controlled crossover stud...

journal_title：International journal of endocrinology

authors： Tura A,Farngren J,Schweizer A,Foley JE,Pacini G,Ahrén B

更新日期：2015-01-01 00:00:00

abstract：:The aim of this study is to investigate the circulating OPG levels in postmenopausal women with diabetes and prediabetes and explore the relationships between serum OPG and insulin resistance. A total of 271 unrelated Chinese postmenopausal women were recruited in this study. The subjects were divided into type 2 diab...

journal_title：International journal of endocrinology

authors： Duan P,Yang M,Wei M,Liu J,Tu P

更新日期：2017-01-01 00:00:00

abstract：Purpose:Hyperoside, a flavonoid isolated from conventional medicinal herbs, has been demonstrated to exert a significant protective effect in diabetic nephropathy. This study aimed to determine the underlying mechanisms, by which hyperoside inhibits high glucose-(HG-) induced proliferation in mouse renal mesangial cell...

journal_title：International journal of endocrinology

authors： Zhang L,Dai Q,Hu L,Yu H,Qiu J,Zhou J,Long M,Zhou S,Zhang K

更新日期：2020-07-21 00:00:00

abstract：:Type 2 diabetes mellitus (T2D) is a disorder of glucose metabolism. It is a complex process involving the regulation of insulin secretion, insulin sensitivity, gluconeogenesis, and glucose uptake at the cellular level. Diabetic peripheral neuropathy (DPN) is one of the debilitating complications that is present in app...

journal_title：International journal of endocrinology

authors： Prabodha LBL,Sirisena ND,Dissanayake VHW

更新日期：2018-03-15 00:00:00

abstract：:Sex steroid hormones have neuroprotective properties which may be mediated by brain-derived neurotrophic factor (BDNF). This study sought to determine the interactive effects of preadolescent hormone manipulation and BDNF heterozygosity (+/-) on hippocampal NMDA-R expression. Wild-type and BDNF+/- mice were gonadectom...

journal_title：International journal of endocrinology

authors： McCarthny CR,Du X,Wu YC,Hill RA

更新日期：2018-01-31 00:00:00

abstract：Objectives:To compare the predictive ability of six anthropometric indices for identification of metabolic syndrome (MetS) and to determine their optimal cut-off points among Chinese adults. Methods:A total of 59,029 participants were enrolled. Body mass index (BMI), waist circumference (WC), waist-to-height ratio (WH...

journal_title：International journal of endocrinology

authors： Zhang J,Zhu W,Qiu L,Huang L,Fang L

更新日期：2018-09-17 00:00:00

abstract：:Type 2 diabetes is characterized by frequent ectopic fat accumulation in several tissues and organs. In particular, a number of studies showed that these subjects frequently have hepatic fat accumulation, which may play a role in the metabolic abnormalities typical of diabetes and has been also linked to increased ris...

journal_title：International journal of endocrinology

authors： Bacchi E,Moghetti P

更新日期：2013-01-01 00:00:00

abstract：:Purpose. To evaluate whether inferior rectus muscle (IRM) thickness, the degree of adipose change in the IRM, smoking status, and the previous history of orbital radiotherapy can predict the dose-effect relationship regarding unilateral IRM recession in thyroid eye disease (TED). Methods. Twenty-five patients were ret...

journal_title：International journal of endocrinology

authors： Takahashi Y,Kakizaki H

更新日期：2015-01-01 00:00:00

abstract：:Objective. To identify factors predicting the need for insulin therapy in pregnancies complicated by gestational diabetes mellitus (GDM). Methods. A total of 1352 patients with GDM diagnosed by the 75-g/2-h oral glucose tolerance test (OGTT) were enrolled in this study. Univariate and multivariate analysis were perfor...

journal_title：International journal of endocrinology

authors： Zhang Y,Shao J,Li F,Xu X

更新日期：2016-01-01 00:00:00

abstract：:From January 1987 to December 2011, over a total of 25 years, 84 patients with Cushing's syndrome (CS) were identified at a medical center in southern Taiwan. We observed a higher incidence of ACTH-independent CS (75%) than ACTH-dependent CS (25%). A higher incidence of adrenocortical adenoma (58.3%) than Cushing's di...

journal_title：International journal of endocrinology

authors： Tung SC,Wang PW,Liu RT,Chen JF,Hsieh CJ,Kuo MC,Yang JW,Lee WC,Cheng MH,Lee TC

更新日期：2013-01-01 00:00:00

abstract：:Type 2 diabetes and depression are regarded as comorbid conditions, and three possible directions of the association between the diseases can underlie this observation of comorbidity. First, common etiology can increase a person's risk of both diseases; second, persons with type 2 diabetes have increased prevalence or...

journal_title：International journal of endocrinology

authors： Berge LI,Riise T

更新日期：2015-01-01 00:00:00

abstract：Objective:To evaluate the effectiveness and safety of coenzyme Q10 for patients with type 2 diabetes mellitus (T2DM). Methods:Data from randomized controlled trials were obtained to assess the effects of coenzyme Q10 versus placebo or western medicine on patients with T2DM. The study's registration number is CRD420180...

journal_title：International journal of endocrinology

authors： Zhang SY,Yang KL,Zeng LT,Wu XH,Huang HY

更新日期：2018-09-16 00:00:00

abstract：:While vitamin D3 is recognized as a neuroactive steroid affecting both brain development and function, efficient analytical method in determining vitamin D3 metabolites in the brain tissue is still lacking, and the relationship of vitamin D3 status between serum and brain remains elusive. Therefore, we developed a nov...

journal_title：International journal of endocrinology

authors： Xue Y,He X,Li HD,Deng Y,Yan M,Cai HL,Tang MM,Dang RL,Jiang P

更新日期：2015-01-01 00:00:00

abstract：:Objectives. Statin drugs act as inhibitors of the 3-hydroxy-3methylglutaryl coenzyme A (HMG-CoA) reductase enzyme early in the mevalonate pathway, thereby reducing the endogenous cholesterol synthesis. In recent studies, it has been suggested from epidemiological data that statins also may improve vitamin D status, as...

journal_title：International journal of endocrinology

authors： Rejnmark L,Vestergaard P,Heickendorff L,Mosekilde L

更新日期：2010-01-01 00:00:00

abstract：:We aimed to estimate the impact of ingestion of a pure protein load on the glucose levels in T1DM patients treated with insulin pumps. We examined 10 T1DM patients (6 females, mean age-32.3 years, mean HbA1c-6.8%) treated with insulin pumps equipped with a continuous glucose monitoring system (CGMS). In Phase I, basel...

journal_title：International journal of endocrinology

authors： Klupa T,Benbenek-Klupa T,Matejko B,Mrozinska S,Malecki MT

更新日期：2015-01-01 00:00:00

abstract：:To investigate effects of long-term testosterone (T) therapy in obese men with T deficiency (TD) and type 2 diabetes mellitus (T2DM), data were collected from two observational, prospective, and cumulative registry studies of 561 men with TD receiving T therapy for up to 6 years. A subgroup of obese hypogonadal men wi...

journal_title：International journal of endocrinology

authors： Haider A,Yassin A,Doros G,Saad F

更新日期：2014-01-01 00:00:00

abstract：:Leptin and adiponectin are differentially expressed adipokines in obesity and cardiovascular diseases. Leptin levels are directly associated with adipose tissue mass, while adiponectin levels are downregulated in obesity. Although significantly produced by adipocytes, leptin is also produced by vascular smooth muscle ...

journal_title：International journal of endocrinology

authors： Ghantous CM,Azrak Z,Hanache S,Abou-Kheir W,Zeidan A

更新日期：2015-01-01 00:00:00

abstract：:Objective. Black thyroid is a rare pigmented change seen almost exclusively in patients upon minocycline ingestion, and the process has previously been thought to be generally benign. There have been 61 reported cases of black thyroid. We are aware of 13 cases previously reported in association with thyroid carcinoma....

journal_title：International journal of endocrinology

authors： Kandil E,Abdel Khalek M,Alabbas H,Daroca P,Thethi T,Friedlander P,Leblanc R,Abdullah O,Jaffe B,Crawford B

更新日期：2010-01-01 00:00:00

abstract：:The risk for cardiovascular diseases and type 2 diabetes mellitus significantly increases in the patient population with metabolic syndrome (MeS). The present study aimed to investigate the association between the epicardial adipose tissue thickness (EATT) and the oxidative stress parameters in MeS patients. The study...

journal_title：International journal of endocrinology

authors： Demir B,Demir E,Acıksarı G,Uygun T,Utku IK,Gedikbasi A,Caglar IM,Pirhan O,Tureli HO,Oflar E,Ungan İ,Ciftci S,Karakaya O

更新日期：2014-01-01 00:00:00

abstract：:Background. The purpose of the present study was to assess the feasibility of using miR-126 in the urine as a biomarker for diabetic nephropathy. Methods. miRNAs were extracted from the urine samples of T2DM patients with diabetic nephropathy (DN; n = 92), T2DM without DN (n = 86), and 85 healthy volunteers using quan...

journal_title：International journal of endocrinology

authors： Liu Y,Gao G,Yang C,Zhou K,Shen B,Liang H,Jiang X

更新日期：2014-01-01 00:00:00

abstract：Aim:To clarify the contributions of fasting glucose (FG) and postprandial glucose (PG) to HbA1c in drug-naïve patients with type 2 diabetes (T2D) and impaired glucose tolerate (IGT)/impaired fasting glucose (IFG). Methods:Continuous glucose monitoring (CGM) was performed in 305 drug-naïve Chinese patients with T2D or ...

journal_title：International journal of endocrinology

authors： Yan R,Hu Y,Li F,Jiang L,Xu X,Wang J,Zhang Y,Ye L,Lee KO,Su X,Ma J

更新日期：2019-12-01 00:00:00

abstract：:In the last decade, miRNAs have received substantial attention as potential players of diabetes microvascular complications, affecting the kidney, the retina, and the peripheral neurons. Compelling evidence indicates that abnormally expressed miRNAs have pivotal roles in key pathogenic processes of microvascular compl...

journal_title：International journal of endocrinology

authors： Barutta F,Bellini S,Mastrocola R,Bruno G,Gruden G

更新日期：2018-03-07 00:00:00

abstract：:Thyroid cancer is the most common endocrine malignancy, and its incidence has increased rapidly in recent decades worldwide. Papillary thyroid cancer (PTC) is the most common type of all thyroid cancers. The molecular mechanisms underlying the disease still need to be further investigated. Long noncoding RNAs (lncRNAs...

journal_title：International journal of endocrinology

authors： Choy M,Guo Y,Li H,Wei G,Ye R,Liang W,Xiao H,Li Y,Guan H

更新日期：2019-04-07 00:00:00

abstract：:Gestational diabetes mellitus (GDM) is defined as any degree of carbohydrate intolerance, with onset or first recognition during second or third trimester of gestation. It is estimated that approximately 7% of all pregnancies are complicated by GDM and that its prevalence is rising all over the world. Thus, the screen...

journal_title：International journal of endocrinology

authors： Guarino E,Delli Poggi C,Grieco GE,Cenci V,Ceccarelli E,Crisci I,Sebastiani G,Dotta F

更新日期：2018-04-12 00:00:00

abstract：:Aim. To compare two creatinine-based estimated glomerular filtration rate (eGFR) equations, the chronic kidney disease epidemiology collaboration (CKD-EPI) and the modification of diet in renal disease (MDRD), for predicting the risk of CKD progression in type 2 diabetic patients with nephropathy. Methods. A total of ...

journal_title：International journal of endocrinology

authors： Lee EY,Lee YM,Choi KH,Lee HC,Lee BW,Kim BS

更新日期：2013-01-01 00:00:00

abstract：:The main purpose of our retrospective study was to evaluate the medical care of the patients with subclinical hypothyroidism (sHT) and to investigate the rationale for administering L-thyroxine (LT-4) to young sHT patients. Patients and Methods. Based on a retrospective review of the charts of 261 patients referred to...

journal_title：International journal of endocrinology

authors： Such K,Gawlik A,Dejner A,Wasniewska M,Zachurzok A,Antosz A,Gawlik T,Malecka-Tendera E

更新日期：2016-01-01 00:00:00

abstract：Background:Gonadal injury following chemotherapy is of increasing importance with the continuous improvement of survival rates. The protection of gonadotropin hormone antagonist (GnRHant) in long-term adult survivors of adolescent cancers and some autoimmune diseases has not yet been evaluated. Methods:The present stu...

journal_title：International journal of endocrinology

authors： Xie R,Chen L,Wu H,Chen T,Wang F,Chen X,Sun H,Li X

更新日期：2018-06-10 00:00:00