GnRH Antagonist Improves Pubertal Cyclophosphamide-Induced Long-Term Testicular Injury in Adult Rats.

abstract：Purpose:Primary hypertrophic osteoarthropathy (PHO) is a rare, autosomal, recessive genetic disease characterized by digital clubbing, periostosis, and pachydermia. The underlying cause for the pathogenesis of this disease is a defect in prostaglandin E2 (PGE2) degradation, caused by mutations in HPGD or SLCO2A1. In th...

journal_title：International journal of endocrinology

authors： Li N,Ma Y,Jiang Y,You L,Huang Y,Peng Y,Ding X,Zhao L

更新日期：2020-12-03 00:00:00

abstract：:Anaplastic thyroid cancers (ATC) are among the most aggressive human neoplasms with a dire prognosis and a median survival time of few months from the diagnosis. The complete absence of effective therapies for ATC renders the identification of novel therapeutic approaches sorely needed. Chromosomal instability, a feat...

journal_title：International journal of endocrinology

authors： Baldini E,D'Armiento M,Ulisse S

更新日期：2014-01-01 00:00:00

abstract：:The presence of brown adipose tissue (BAT) in humans is unclear. Pheochromocytomas (PHEO) are rare tumors of neuroectodermal origin which occur in 0.1-0.2% of patients with hypertension. We sought to evaluate the presence and activity of BAT surrounding adrenal PHEO in a well-studied sample of 11 patients who were dia...

journal_title：International journal of endocrinology

authors： Iacobellis G,Di Gioia C,Petramala L,Chiappetta C,Serra V,Zinnamosca L,Marinelli C,Ciardi A,De Toma G,Letizia C

更新日期：2013-01-01 00:00:00

abstract：:Objective. To analyze changes in vital signs (heart rate (HR), systolic (SBP), and diastolic blood pressure (DBP)) during and after intravenous methylprednisolone (IVMP) and any other adverse effects. Methods. Retrospective review of charts of patients who received IVMP as treatment regime for thyroid eye disease. All...

journal_title：International journal of endocrinology

authors： Yong KL,Chng CL,Htoon HM,Lim LH,Seah LL

更新日期：2015-01-01 00:00:00

abstract：:Thyroid nodules, with their high prevalence in the general population, represent a diagnostic challenge for clinicians. Ultrasound (US), although absolutely reliable in detecting thyroid nodules, is still not accurate enough to differentiate them into benign and malignant. A promising novel modality, US elastography, ...

journal_title：International journal of endocrinology

authors： Cantisani V,Grazhdani H,Drakonaki E,D'Andrea V,Di Segni M,Kaleshi E,Calliada F,Catalano C,Redler A,Brunese L,Drudi FM,Fumarola A,Carbotta G,Frattaroli F,Di Leo N,Ciccariello M,Caratozzolo M,D'Ambrosio F

更新日期：2015-01-01 00:00:00

abstract：:Parathyroid carcinoma (PC) is a rare disease responsible for about 1% of primary hyperparathyroidism (PHPT) cases. PC usually has an indolent course, tough to differentiate from the benign causes of PHPT, and the only certain diagnosis is histologic. The gold standard surgical treatment is the en bloc resection associ...

journal_title：International journal of endocrinology

authors： Quaglino F,Manfrino L,Cestino L,Giusti M,Mazza E,Piovesan A,Palestini N,Lauro C,Castellano E

更新日期：2020-03-06 00:00:00

abstract：:Whether serum magnesium deficiency is independently associated with the prevalence of microalbuminuria is still unclear. The objective of the present study was to elucidate the association between serum magnesium and microalbuminuria in diabetic patients. A cross-sectional study was conducted in 1829 diabetic subjects...

journal_title：International journal of endocrinology

authors： Xu B,Sun J,Deng X,Huang X,Sun W,Xu Y,Xu M,Lu J,Bi Y

更新日期：2013-01-01 00:00:00

abstract：:Introduction. Differentiated thyroid cancer treatment usually consists of thyroidectomy and radio ablation in hypothyroidism 4-6 weeks after surgery. Replacing hypothyroidism by recombinant human thyroid stimulating hormone can facilitate radio ablation in euthyroidism within one week after surgery. The outcome of thi...

journal_title：International journal of endocrinology

authors： Emmanouilidis N,Schrem H,Winkler M,Klempnauer J,Scheumann GF

更新日期：2013-01-01 00:00:00

abstract：:The 5-alpha-reductase type 2 deficiency (5ARD2) is an autosomal recessive condition associated with impairment in the conversion of testosterone to dihydrotestosterone. This condition leads to undervirilisation in 46,XY individuals. To date, there have been more than 100 variations identified in the gene responsible f...

journal_title：International journal of endocrinology

authors： Marzuki NS,Idris FP,Kartapradja HD,Harahap AR,Batubara JRL

更新日期：2019-12-01 00:00:00

abstract：:Present therapies to minify hyperglycaemia and insulin resistance mainly target ATP-sensitive K(+) channels (K(ATP)) of pancreatic cells and PPAR-γ to enhance the insulin secretion and potential for GLUT expression, respectively. These current approaches are frequently associated with the various side effects such as ...

journal_title：International journal of endocrinology

authors： Ahmed D,Sharma M

更新日期：2011-01-01 00:00:00

abstract：:Aims. To evaluate the predictive power of pretransplant HbA1c for new-onset diabetes after transplantation (NODAT) in kidney transplant candidates, who had several predispositions for fluctuated HbA1c levels. Methods. We performed a retrospective study of 119 patients without diabetes who received kidney transplantati...

journal_title：International journal of endocrinology

authors： Tokodai K,Amada N,Haga I,Nakamura A,Kashiwadate T,Kawagishi N,Ohuchi N

更新日期：2014-01-01 00:00:00

abstract：:In the present study we evaluated in vivo and in vitro effects of 4-tert-octylphenol (OP) on the expression and distribution of adherens and gap junction proteins, N-cadherin, β -catenin, and connexin 43 (Cx43), in testes of seasonally breeding rodents, bank voles. We found that in bank vole testes expression and dist...

journal_title：International journal of endocrinology

authors： Hejmej A,Kotula-Balak M,Chojnacka K,Kuras P,Lydka-Zarzycka M,Bilinska B

更新日期：2013-01-01 00:00:00

abstract：:Sunlight-induced vitamin D, synthesis in the skin is the major source of vitamin D, but data on the relationship of sun-related behaviour with vitamin D and parathyroid hormone (PTH) levels are relatively sparse. We evaluated whether habitual sun exposure is associated with 25-hydroxyvitamin D (25[OH]D) and PTH levels...

journal_title：International journal of endocrinology

authors： Pilz S,Kienreich K,Stückler D,Meinitzer A,Tomaschitz A

更新日期：2012-01-01 00:00:00

abstract：:To isolate pancreatic progenitor cells with the surface markers of hematopoietic stem cells, the expression of stem cell antigen (Sca-1) and c-Kit and the coexpression of them with pancreatic duodenal homeobox-1 (PDX-1), neurogenin 3 (Ngn3), and insulin were examined in murine embryonic pancreas. Then different pancre...

journal_title：International journal of endocrinology

authors： Ma F,Chen F,Chi Y,Yang S,Lu S,Han Z

更新日期：2012-01-01 00:00:00

abstract：:The circadian system is a supraphysiological system that modulates different biological functions such as metabolism, sleep-wake, cellular proliferation, and body temperature. Different chronodisruptors have been identified, such as shift work, feeding time, long days, and stress. The environmental changes and our mod...

journal_title：International journal of endocrinology

authors： Valenzuela FJ,Vera J,Venegas C,Muñoz S,Oyarce S,Muñoz K,Lagunas C

更新日期：2016-01-01 00:00:00

abstract：Background:Little information is available on the association between parents' metabolic syndrome (MetS) and adolescent offspring's obesity in Korea. The aim of our study is to determine the association between parent's metabolic syndrome and offspring's obesity. Methods:The study data were obtained from the Korean Na...

journal_title：International journal of endocrinology

authors： Lee NY,Han K,Lee Y,Kim S,Lee S,Choi Y,Ahn MB,Kim SH,Cho WK,Cho KS,Jung MH,Park YG,Suh BK

更新日期：2020-10-30 00:00:00

abstract：:HDL cholesterol is known to be inversely correlated with cardiovascular disease due to its diverse antiatherogenic functions. SR-BI mediates the selective uptake of HDL-C. SR-BI knockout diminishes but does not completely block the transport of HDL; other receptors may be involved. Ectopic ATP synthase β-chain in hepa...

journal_title：International journal of endocrinology

authors： Song K,Han Y,Zhang L,Liu G,Yang P,Cheng X,Bu L,Sheng H,Qu S

更新日期：2014-01-01 00:00:00

abstract：:The main purpose of our retrospective study was to evaluate the medical care of the patients with subclinical hypothyroidism (sHT) and to investigate the rationale for administering L-thyroxine (LT-4) to young sHT patients. Patients and Methods. Based on a retrospective review of the charts of 261 patients referred to...

journal_title：International journal of endocrinology

authors： Such K,Gawlik A,Dejner A,Wasniewska M,Zachurzok A,Antosz A,Gawlik T,Malecka-Tendera E

更新日期：2016-01-01 00:00:00

abstract：:To investigate effects of long-term testosterone (T) therapy in obese men with T deficiency (TD) and type 2 diabetes mellitus (T2DM), data were collected from two observational, prospective, and cumulative registry studies of 561 men with TD receiving T therapy for up to 6 years. A subgroup of obese hypogonadal men wi...

journal_title：International journal of endocrinology

authors： Haider A,Yassin A,Doros G,Saad F

更新日期：2014-01-01 00:00:00

abstract：Objective:We sought to evaluate the association between femoral neck (FN) and lumbar spine (LS) bone mineral densities (BMDs) with severity of chronic kidney disease (CKD) and prevalence of osteopenia or osteoporosis (OP) among the CKD group. Methods:Cross-sectional data from 11050 participants aged ≥20 years from the...

journal_title：International journal of endocrinology

authors： Huang JF,Zheng XQ,Sun XL,Zhou X,Liu J,Li YM,Wang XY,Zhang XL,Wu AM

更新日期：2020-10-26 00:00:00

abstract：Background:gp91phox, the catalytic core of NADPH oxidase (NOX) and biomarker of NOX activation, has been recently recognized as a parameter of systemic oxidative stress in several studies. Subclinical hypothyroidism (SH) is characteristic of elevated level of serum thyroid stimulating hormone (TSH) and is frequently ac...

journal_title：International journal of endocrinology

authors： Ma X,Wang F,Zhen X,Zhao L,Fang L,Dong Z,Chen W,Zhou X

更新日期：2020-05-06 00:00:00

abstract：:X-linked Adrenal Hypoplasia Congenita (AHC) is caused by deletions or point mutations in the NR0B1 (DAX1) gene. We present a boy with AHC who came at the age of 25 days in a severe state due to prolonged vomiting and progressive dehydration. Laboratory studies showed prominent hyponatremia and hyperkaliemia but not hy...

journal_title：International journal of endocrinology

authors： Rojek A,Krawczynski MR,Jamsheer A,Sowinska-Seidler A,Iwaniszewska B,Malunowicz E,Niedziela M

更新日期：2016-01-01 00:00:00

abstract：:Aim. Our aim was (1) to determine the frequency of insulin resistance (IR) in patients with Duchenne/Becker muscular dystrophy (DMD/BMD), (2) to identify deleted exons of DMD gene associated with obesity and IR, and (3) to explore some likely molecular mechanisms leading to IR. Materials and Methods. In 66 patients wi...

journal_title：International journal of endocrinology

authors： Rodríguez-Cruz M,Sanchez R,Escobar RE,Cruz-Guzmán Odel R,López-Alarcón M,Bernabe García M,Coral-Vázquez R,Matute G,Velázquez Wong AC

更新日期：2015-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2016/7838290.]. ...

journal_title：International journal of endocrinology

authors： Villagarcía HG,Sabugo V,Castro MC,Schinella G,Castrogiovanni D,Spinedi E,Massa ML,Francini F

更新日期：2018-10-23 00:00:00

abstract：Background:Type 2 diabetes mellitus is a serious public health problem worldwide. Accumulating evidence has shown that β-cell dysfunction is an important mechanism underlying diabetes mellitus. The changes in the physiological state of islet stellate cells (ISCs) and the effects of these cells on β-cell dysfunction is ...

journal_title：International journal of endocrinology

authors： Xu W,Jones PM,Geng H,Li R,Liu X,Li Y,Lv Q,Liu Y,Wang J,Wang X,Sun Z,Liang J

更新日期：2020-02-24 00:00:00

abstract：Objective:Type 2 diabetes (T2DM) is a global epidemic and increases mortality due to its vascular complications. Chemerin has been found to exert a major role in glucose and lipid metabolism. The aim of this study was to explore the correlation between plasma chemerin levels and microangiopathy in patients with T2DM. ...

journal_title：International journal of endocrinology

authors： Gu P,Wang W,Yao Y,Xu Y,Wang L,Zang P,Ma J,Yang C,Liang J,Lu B,Shao J

更新日期：2019-07-16 00:00:00

abstract：Background:Total thyroidectomy (TT) is recommended in the treatment of malignant and benignant thyroid diseases, and, to date, transient hypocalcemia is the most frequent complication after the procedure. We prospectively evaluated the role of vitamin D deficiency as a predictor of postoperative hypocalcemia. Methods:...

journal_title：International journal of endocrinology

authors： Bove A,Dei Rocini C,Di Renzo RM,Farrukh M,Palone G,Chiarini S,Staniscia T

更新日期：2020-10-10 00:00:00

abstract：:Background. Liraglutide (a glucagon-like peptide 1 analog) was used for the treatment of type 2 diabetes (T2DM) which could produce glucose-dependent insulin secretion. Aim. The aim was to investigate whether liraglutide could improve myofibril and mitochondria injury in skeletal muscle and the mechanisms in diabetic ...

journal_title：International journal of endocrinology

authors： Ji W,Chen X,Lv J,Wang M,Ren S,Yuan B,Wang B,Chen L

更新日期：2014-01-01 00:00:00

abstract：:This study investigated potential markers for predicting nonfunctioning pituitary adenoma (NFPA) invasion and recurrence by high-throughput tissue microarray analyses. We retrospectively studied two groups of patients: 60 nonrecurrent NFPA cases that included noninvasion and invasion subtypes and 43 recurrent cases th...

journal_title：International journal of endocrinology

authors： Yao X,Zhang Y,Wu L,Cheng R,Li C,Qu C,Ji H

更新日期：2019-05-16 00:00:00

abstract：:Background. Separate lines of research have shown that menstrual cycling and contextual factors such as the gender of research personnel influence experimental pain reporting. Objectives. This study examines how brief, procedural interactions with female and male experimenters can affect experimentally reported pain (...

journal_title：International journal of endocrinology

authors： Vigil JM,DiDomenico J,Strenth C,Coulombe P,Kruger E,Mueller AA,Guevara Beltran D,Adams I

更新日期：2015-01-01 00:00:00