ATP Synthase β-Chain Overexpression in SR-BI Knockout Mice Increases HDL Uptake and Reduces Plasma HDL Level.

abstract：:Objective. In pediatric central diabetes insipidus (CDI), etiology diagnosis and pituitary function monitoring are usually delayed. This study aimed to illustrate the importance of regular follow-up and pituitary function monitoring in pediatric CDI. Methods. The clinical, hormonal, and neuroradiological characteristi...

journal_title：International journal of endocrinology

authors： Liu W,Wang L,Liu M,Li G

更新日期：2016-01-01 00:00:00

abstract：:The 5-alpha-reductase type 2 deficiency (5ARD2) is an autosomal recessive condition associated with impairment in the conversion of testosterone to dihydrotestosterone. This condition leads to undervirilisation in 46,XY individuals. To date, there have been more than 100 variations identified in the gene responsible f...

journal_title：International journal of endocrinology

authors： Marzuki NS,Idris FP,Kartapradja HD,Harahap AR,Batubara JRL

更新日期：2019-12-01 00:00:00

abstract：:Sunlight-induced vitamin D, synthesis in the skin is the major source of vitamin D, but data on the relationship of sun-related behaviour with vitamin D and parathyroid hormone (PTH) levels are relatively sparse. We evaluated whether habitual sun exposure is associated with 25-hydroxyvitamin D (25[OH]D) and PTH levels...

journal_title：International journal of endocrinology

authors： Pilz S,Kienreich K,Stückler D,Meinitzer A,Tomaschitz A

更新日期：2012-01-01 00:00:00

abstract：:Sex steroid hormones have neuroprotective properties which may be mediated by brain-derived neurotrophic factor (BDNF). This study sought to determine the interactive effects of preadolescent hormone manipulation and BDNF heterozygosity (+/-) on hippocampal NMDA-R expression. Wild-type and BDNF+/- mice were gonadectom...

journal_title：International journal of endocrinology

authors： McCarthny CR,Du X,Wu YC,Hill RA

更新日期：2018-01-31 00:00:00

abstract：Objective:Once-weekly PEGylated recombinant human growth hormone (rhGH) is the sole long-acting GH formulation available currently for pediatric patients with GH deficiency (GHD). The aim of this study was to evaluate the efficacy and safety of PEGylated rhGH therapy compared to daily rhGH therapy in GHD children treat...

journal_title：International journal of endocrinology

authors： Qiao Y,Wang Z,Han J,Li G

更新日期：2019-09-19 00:00:00

abstract：:Aim. Our aim was (1) to determine the frequency of insulin resistance (IR) in patients with Duchenne/Becker muscular dystrophy (DMD/BMD), (2) to identify deleted exons of DMD gene associated with obesity and IR, and (3) to explore some likely molecular mechanisms leading to IR. Materials and Methods. In 66 patients wi...

journal_title：International journal of endocrinology

authors： Rodríguez-Cruz M,Sanchez R,Escobar RE,Cruz-Guzmán Odel R,López-Alarcón M,Bernabe García M,Coral-Vázquez R,Matute G,Velázquez Wong AC

更新日期：2015-01-01 00:00:00

abstract：:The presence of brown adipose tissue (BAT) in humans is unclear. Pheochromocytomas (PHEO) are rare tumors of neuroectodermal origin which occur in 0.1-0.2% of patients with hypertension. We sought to evaluate the presence and activity of BAT surrounding adrenal PHEO in a well-studied sample of 11 patients who were dia...

journal_title：International journal of endocrinology

authors： Iacobellis G,Di Gioia C,Petramala L,Chiappetta C,Serra V,Zinnamosca L,Marinelli C,Ciardi A,De Toma G,Letizia C

更新日期：2013-01-01 00:00:00

abstract：Aim:To clarify the contributions of fasting glucose (FG) and postprandial glucose (PG) to HbA1c in drug-naïve patients with type 2 diabetes (T2D) and impaired glucose tolerate (IGT)/impaired fasting glucose (IFG). Methods:Continuous glucose monitoring (CGM) was performed in 305 drug-naïve Chinese patients with T2D or ...

journal_title：International journal of endocrinology

authors： Yan R,Hu Y,Li F,Jiang L,Xu X,Wang J,Zhang Y,Ye L,Lee KO,Su X,Ma J

更新日期：2019-12-01 00:00:00

abstract：:Introduction. Differentiated thyroid cancer treatment usually consists of thyroidectomy and radio ablation in hypothyroidism 4-6 weeks after surgery. Replacing hypothyroidism by recombinant human thyroid stimulating hormone can facilitate radio ablation in euthyroidism within one week after surgery. The outcome of thi...

journal_title：International journal of endocrinology

authors： Emmanouilidis N,Schrem H,Winkler M,Klempnauer J,Scheumann GF

更新日期：2013-01-01 00:00:00

abstract：:Purpose. We investigate the usefulness of multimodal assistant systems using a fusion model of preoperative three-dimensional (3D) computed tomography (CT) and magnetic resonance imaging (MRI) along with endoscopy with indocyanine green (ICG) fluorescence in establishing endoscopic endonasal transsphenoidal surgery (E...

journal_title：International journal of endocrinology

authors： Inoue A,Ohnishi T,Kohno S,Nishida N,Nakamura Y,Ohtsuka Y,Matsumoto S,Ohue S

更新日期：2015-01-01 00:00:00

abstract：:Endocannabinoids and their G-protein coupled receptors (GPCR) are a current research focus in the area of obesity due to the system's role in food intake and glucose and lipid metabolism. Importantly, overweight and obese individuals often have higher circulating levels of the arachidonic acid-derived endocannabinoids...

journal_title：International journal of endocrinology

authors： Naughton SS,Mathai ML,Hryciw DH,McAinch AJ

更新日期：2013-01-01 00:00:00

abstract：:To examine the gene expression of ghrelin, a growth hormone releasing and appetite stimulating hormone from stomach, we constructed human ghrelin promoter-reporter vectors and analyzed the promoter activity. The ghrelin promoter activity was high when cultured cells that express ghrelin mRNA endogenously like TT or EC...

journal_title：International journal of endocrinology

authors： Shiimura Y,Ohgusu H,Sato T,Kojima M

更新日期：2015-01-01 00:00:00

abstract：:A considerable increase in endocrine abnormalities has been reported over the last few decades worldwide. A growing exposure to endocrine-disrupting chemicals (EDCs) can be one of the causes of endocrine disorders in populations, and these disorders are not only restricted to the metabolic hormone system but can also ...

journal_title：International journal of endocrinology

authors： de Oliveira M,Rodrigues BM,Olimpio RMC,Graceli JB,Gonçalves BM,Costa SMB,da Silva TM,De Sibio MT,Moretto FCF,Mathias LS,Cardoso DBM,Tilli HP,Freitas-Lima LC,Nogueira CR

更新日期：2019-04-17 00:00:00

abstract：:Objectives. Growth hormone deficiency patients exhibited reduced bone mineral density compared with healthy controls, but previous researches demonstrated uncertainty about the effect of growth hormone replacement therapy on bone in growth hormone deficient adults. The aim of this study was to determine whether the gr...

journal_title：International journal of endocrinology

authors： Xue P,Wang Y,Yang J,Li Y

更新日期：2013-01-01 00:00:00

abstract：:Objective. To examine the association of three most common obesity measures including body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR) with chronic kidney disease (CKD) risk in patients with type 2 diabetes mellitus (T2D). Design. Cross-sectional evaluation of the effect of anthropometric ...

journal_title：International journal of endocrinology

authors： Xu L,Yu W,Huang P,Li C,Li Y,Wang M,Xu Q,Wang J,Zheng C,Qu B,Zhao Y,Niu M,Wang O,Gong F

更新日期：2015-01-01 00:00:00

abstract：:While vitamin D3 is recognized as a neuroactive steroid affecting both brain development and function, efficient analytical method in determining vitamin D3 metabolites in the brain tissue is still lacking, and the relationship of vitamin D3 status between serum and brain remains elusive. Therefore, we developed a nov...

journal_title：International journal of endocrinology

authors： Xue Y,He X,Li HD,Deng Y,Yan M,Cai HL,Tang MM,Dang RL,Jiang P

更新日期：2015-01-01 00:00:00

abstract：:Growth failure is almost inextricably linked with chronic kidney disease (CKD) and end-stage renal disease (ESRD). Growth failure in CKD has been associated with both increased morbidity and mortality. Growth failure in the setting of kidney disease is multifactorial and is related to poor nutritional status as well a...

journal_title：International journal of endocrinology

authors： Salas P,Pinto V,Rodriguez J,Zambrano MJ,Mericq V

更新日期：2013-01-01 00:00:00

abstract：:Point-of-care (POC) glucose technology is currently considered to be insufficiently accurate for the diagnosis of diabetes. The objective of this study was to investigate the diagnostic accuracy of an innovative, interference-resistant POC glucose meter (StatStrip glucose hospital meter, Nova Biomedical, USA) in subje...

journal_title：International journal of endocrinology

authors： Vučić Lovrenčić M,Radišić Biljak V,Božičević S,Pape-Medvidović E,Ljubić S

更新日期：2013-01-01 00:00:00

abstract：:Background. Hyperinsulinaemic Hypoglycaemia (HH) is the most common cause of severe and persistent hypoglycemia in the neonatal period. It has been shown that the neonates with HH fail to generate adequate serum cortisol counterregulatory response to symptomatic hypoglycemia. However the role played by growth hormone ...

journal_title：International journal of endocrinology

authors： Senniappan S,Hussain K

更新日期：2013-01-01 00:00:00

abstract：:Glucose is the major source of energy for the human brain which in turn uses ketone bodies as a supplement for energy deficit in glucose cell deficiency conditions. Pregnancy complicated by gestational diabetes is a condition associated with significantly increased risk of ketonemia development. The data available pro...

journal_title：International journal of endocrinology

authors： Bronisz A,Ozorowski M,Hagner-Derengowska M

更新日期：2018-06-04 00:00:00

abstract：:The objective of this cross-sectional study was to assess differences in the control and treatment of modifiable cardiovascular risk factors (CVRF: HbA1c, blood pressure [BP], LDL-cholesterol, body mass index, and smoking habit) according to gender and the presence of cardiovascular disease (CVD) in patients with type...

journal_title：International journal of endocrinology

authors： Franch-Nadal J,Mata-Cases M,Vinagre I,Patitucci F,Hermosilla E,Casellas A,Bolivar B,Mauricio D

更新日期：2014-01-01 00:00:00

abstract：Objective:To evaluate the effectiveness and safety of coenzyme Q10 for patients with type 2 diabetes mellitus (T2DM). Methods:Data from randomized controlled trials were obtained to assess the effects of coenzyme Q10 versus placebo or western medicine on patients with T2DM. The study's registration number is CRD420180...

journal_title：International journal of endocrinology

authors： Zhang SY,Yang KL,Zeng LT,Wu XH,Huang HY

更新日期：2018-09-16 00:00:00

abstract：:Anaplastic thyroid cancers (ATC) are among the most aggressive human neoplasms with a dire prognosis and a median survival time of few months from the diagnosis. The complete absence of effective therapies for ATC renders the identification of novel therapeutic approaches sorely needed. Chromosomal instability, a feat...

journal_title：International journal of endocrinology

authors： Baldini E,D'Armiento M,Ulisse S

更新日期：2014-01-01 00:00:00

abstract：:The role of angiogenesis in pituitary tumor development has been questioned, as pituitary tumors have been usually found to be less vascularized than the normal pituitary tissue. Nevertheless, a significantly higher degree of vasculature has been shown in invasive or macropituitary prolactinomas when compared to nonin...

journal_title：International journal of endocrinology

authors： Cristina C,Luque GM,Demarchi G,Lopez Vicchi F,Zubeldia-Brenner L,Perez Millan MI,Perrone S,Ornstein AM,Lacau-Mengido IM,Berner SI,Becu-Villalobos D

更新日期：2014-01-01 00:00:00

abstract：Background:Currently, energy obtained from hypercaloric diets has been part of the obesity and type 2 diabetes mellitus (T2DM) epidemics from childhood to old age. Treatment alternatives have been sought from plants, minerals, and trace elements with metabolic effects. Vanadyl sulfate (VS) has been investigated as a hy...

journal_title：International journal of endocrinology

authors： Ortega-Pacheco D,Jiménez-Pérez MM,Serafín-López J,Juárez-Rojas JG,Ruiz-García A,Pacheco-García U

更新日期：2018-12-25 00:00:00

abstract：:The increased prevalence of obesity represents, currently, one of the major public health issues, due to its consequences on physical and psychological health status as well as on the psychosocial functioning. As defined by the World Health Organization, sexual health is "a state of physical, emotional, mental, and so...

journal_title：International journal of endocrinology

authors： Poggiogalle E,Di Lazzaro L,Pinto A,Migliaccio S,Lenzi A,Donini LM

更新日期：2014-01-01 00:00:00

abstract：:Hypogonadotropic hypogonadism (HH) can be sustained by organic or functional alterations of the hypothalamic-pituitary-testicular axis. Functional HH is related to systemic alterations, such as obesity or chronic inflammatory diseases, but could contribute to a negative course of the illness. For such situation, accor...

journal_title：International journal of endocrinology

authors： Giagulli VA,Silvestrini A,Bruno C,Triggiani V,Mordente A,Mancini A

更新日期：2020-01-21 00:00:00

abstract：Background:The aim was to investigate the amounts of saliva and serum asprosin in order to determine whether it is related to obesity and whether salivary glands synthesize asprosin or not. Methods:A total of 116 underweight, normal weight, overweight, and obese (class I, class II, and class III) volunteers participat...

journal_title：International journal of endocrinology

authors： Ugur K,Aydin S

更新日期：2019-03-27 00:00:00

abstract：:Puerarin, the main isoflavone glycoside extracted from Radix Puerariae, is an isoflavone traditional Chinese herb. Previous studies have demonstrated that puerarin could regulate osteoblast proliferation and differentiation to promote bone formation. However, the effect of puerarin on the process of human osteoblasts ...

journal_title：International journal of endocrinology

authors： Liu LJ,Liu LQ,Bo T,Li SJ,Zhu Z,Cui RR,Mao DA

更新日期：2013-01-01 00:00:00

abstract：:The main purpose of our retrospective study was to evaluate the medical care of the patients with subclinical hypothyroidism (sHT) and to investigate the rationale for administering L-thyroxine (LT-4) to young sHT patients. Patients and Methods. Based on a retrospective review of the charts of 261 patients referred to...

journal_title：International journal of endocrinology

authors： Such K,Gawlik A,Dejner A,Wasniewska M,Zachurzok A,Antosz A,Gawlik T,Malecka-Tendera E

更新日期：2016-01-01 00:00:00