Fatty Acid modulation of the endocannabinoid system and the effect on food intake and metabolism.

abstract：Introduction:Gut microbiota is involved in the progression of metabolic diseases such as obesity and type 2 diabetes. The ob/ob and db/db mice are extensively used as models in studies on the pathogenesis of these diseases. The goal of this study is to characterize the composition and structure of gut microbiota in the...

journal_title：International journal of endocrinology

authors： Yang M,Liu Y,Xie H,Wen Z,Zhang Y,Wu C,Huang L,Wu J,Xie C,Wang T,Peng W,Liu S,Chen L,Liu X

更新日期：2019-03-11 00:00:00

abstract：:Objectives. Vitamin D deficiency plays a role in insulin resistance and the pathogenesis of type 2 diabetes mellitus. Little information is available about the association between vitamin D status and insulin resistance in the Chinese population. Currently, vitamin D status is evaluated by the concentrations of serum ...

journal_title：International journal of endocrinology

authors： Zhang J,Ye J,Guo G,Lan Z,Li X,Pan Z,Rao X,Zheng Z,Luo F,Lin L,Lin Z,Xue Y

更新日期：2016-01-01 00:00:00

abstract：:There is inconsistency among published guidelines for the optimal diagnostic and management pathways for patients with typical (TC) or atypical (AC) pulmonary carcinoid tumours. We conducted a UK-wide clinician survey to assess current practice for the diagnosis, management, and follow-up of patients with TC/AC and de...

journal_title：International journal of endocrinology

authors： Mansoor W,Ferguson S,Ross V,Talbot D

更新日期：2020-02-28 00:00:00

abstract：:Iodine supplementation through salt iodization is a worldwide, effective strategy for preventing iodine deficiency-related problems. Its safety and efficacy profile has been extensively investigated, and benefits far outweigh the potential iodine-induced risks. Moreover, iodine supplementation during pregnancy in orde...

journal_title：International journal of endocrinology

authors： Prete A,Paragliola RM,Corsello SM

更新日期：2015-01-01 00:00:00

abstract：:Objective. Black thyroid is a rare pigmented change seen almost exclusively in patients upon minocycline ingestion, and the process has previously been thought to be generally benign. There have been 61 reported cases of black thyroid. We are aware of 13 cases previously reported in association with thyroid carcinoma....

journal_title：International journal of endocrinology

authors： Kandil E,Abdel Khalek M,Alabbas H,Daroca P,Thethi T,Friedlander P,Leblanc R,Abdullah O,Jaffe B,Crawford B

更新日期：2010-01-01 00:00:00

abstract：:The chemosensitivity of anaplastic thyroid cancer (ATC) to some cytotoxic agents was investigated by the histoculture drug response assay (HDRA). Thirty specimens from 22 patients with ATC were obtained from surgically resected subjects. The drugs tested were paclitaxel (PTX), docetaxel (DOC), adriamycin (ADM), nedapl...

journal_title：International journal of endocrinology

authors： Uruno T,Masaki C,Akaishi J,Matsuzu K,Suzuki A,Ohkuwa K,Shibuya H,Kitagawa W,Nagahama M,Sugino K,Ito K

更新日期：2015-01-01 00:00:00

abstract：:Present therapies to minify hyperglycaemia and insulin resistance mainly target ATP-sensitive K(+) channels (K(ATP)) of pancreatic cells and PPAR-γ to enhance the insulin secretion and potential for GLUT expression, respectively. These current approaches are frequently associated with the various side effects such as ...

journal_title：International journal of endocrinology

authors： Ahmed D,Sharma M

更新日期：2011-01-01 00:00:00

abstract：:The objective of this cross-sectional study was to assess differences in the control and treatment of modifiable cardiovascular risk factors (CVRF: HbA1c, blood pressure [BP], LDL-cholesterol, body mass index, and smoking habit) according to gender and the presence of cardiovascular disease (CVD) in patients with type...

journal_title：International journal of endocrinology

authors： Franch-Nadal J,Mata-Cases M,Vinagre I,Patitucci F,Hermosilla E,Casellas A,Bolivar B,Mauricio D

更新日期：2014-01-01 00:00:00

abstract：:Background. Dyslipidemia contribute to the excess of coronary heart disease (CHD) risk observed in women with type 2 diabetes (T2DM). Low density lipoprotein-cholesterol (LDL-C) is the major target for CHD prevention, and T2DM women seem to reach LDL-C targets less frequently than men. Aim. To explore age- and gender-...

journal_title：International journal of endocrinology

authors： Russo G,Pintaudi B,Giorda C,Lucisano G,Nicolucci A,Cristofaro MR,Suraci C,Mulas MF,Napoli A,Rossi MC,Manicardi V

更新日期：2015-01-01 00:00:00

abstract：:Sex steroid hormones have neuroprotective properties which may be mediated by brain-derived neurotrophic factor (BDNF). This study sought to determine the interactive effects of preadolescent hormone manipulation and BDNF heterozygosity (+/-) on hippocampal NMDA-R expression. Wild-type and BDNF+/- mice were gonadectom...

journal_title：International journal of endocrinology

authors： McCarthny CR,Du X,Wu YC,Hill RA

更新日期：2018-01-31 00:00:00

abstract：:The aim of this retrospective study was to evaluate the effects of a treatment with α-lipoic acid (ALA) associated with two different doses of myo-inositol (MI) on clinical and metabolic features of women with polycystic ovary syndrome (PCOS). Eighty-eight women received the treatment, and 71 among them had complete c...

journal_title：International journal of endocrinology

authors： Fruzzetti F,Benelli E,Fidecicchi T,Tonacchera M

更新日期：2020-03-19 00:00:00

abstract：Background:The purpose of the current study is to determine PTH reference values in vitamin-D-replete Lebanese adults using 2nd and 3rd generation PTH assays and to look at the factors that affect PTH variations. Methods:Fasting PTH was measured using 2nd and 3rd generation Diasorin PTH assays in 339 vitamin-D-replete...

journal_title：International journal of endocrinology

authors： Gannagé-Yared MH,Kallas-Chémaly MN,Sleilaty G

更新日期：2020-02-21 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) is the most common endocrine disorder amongst women of reproductive age. Although PCOS is diagnosed exclusively based on reproductive criteria, it is also a metabolic disorder. Insulin resistance, impaired glucose tolerance, type 2 diabetes mellitus, obesity, and dyslipidemia are more ...

journal_title：International journal of endocrinology

authors： Baldani DP,Skrgatic L,Ougouag R

更新日期：2015-01-01 00:00:00

abstract：:Sunlight-induced vitamin D, synthesis in the skin is the major source of vitamin D, but data on the relationship of sun-related behaviour with vitamin D and parathyroid hormone (PTH) levels are relatively sparse. We evaluated whether habitual sun exposure is associated with 25-hydroxyvitamin D (25[OH]D) and PTH levels...

journal_title：International journal of endocrinology

authors： Pilz S,Kienreich K,Stückler D,Meinitzer A,Tomaschitz A

更新日期：2012-01-01 00:00:00

abstract：:Aims. There are two phases of insulin secretion, the first (FPIS) and second phase (SPIS). In this study, we built equations to predict FPIS with metabolic syndrome (MetS) components and fasting plasma insulin (FPI). Methods. Totally, 186 participants were enrolled. 75% of participants were randomly selected as the st...

journal_title：International journal of endocrinology

authors： Lin JD,Hsu CH,Liang YJ,Lian WC,Hsieh CH,Wu CZ,Pei D,Chen YL

更新日期：2015-01-01 00:00:00

abstract：:Anaplastic thyroid carcinoma (ATC) is the most aggressive form of thyroid cancer. It shows a wide spectrum of morphological presentations and the diagnosis could be challenging due to its high degree of dedifferentiation. Molecular and genetic features of ATC are widely heterogeneous as well and many efforts have been...

journal_title：International journal of endocrinology

authors： Ragazzi M,Ciarrocchi A,Sancisi V,Gandolfi G,Bisagni A,Piana S

更新日期：2014-01-01 00:00:00

abstract：Objective:Once-weekly PEGylated recombinant human growth hormone (rhGH) is the sole long-acting GH formulation available currently for pediatric patients with GH deficiency (GHD). The aim of this study was to evaluate the efficacy and safety of PEGylated rhGH therapy compared to daily rhGH therapy in GHD children treat...

journal_title：International journal of endocrinology

authors： Qiao Y,Wang Z,Han J,Li G

更新日期：2019-09-19 00:00:00

abstract：Objectives:To compare the predictive ability of six anthropometric indices for identification of metabolic syndrome (MetS) and to determine their optimal cut-off points among Chinese adults. Methods:A total of 59,029 participants were enrolled. Body mass index (BMI), waist circumference (WC), waist-to-height ratio (WH...

journal_title：International journal of endocrinology

authors： Zhang J,Zhu W,Qiu L,Huang L,Fang L

更新日期：2018-09-17 00:00:00

abstract：OBJECTIVE:Current study was designed to investigate the association of metabolic syndrome (MetS) with depression, anxiety, psychological distress, and quality of life (QoL). DESIGN:Two hundred and fifteen contributors with MetS and 253 participants without MetS were randomly selected from 2151 participants of Isfahan ...

journal_title：International journal of endocrinology

authors： Roohafza H,Sadeghi M,Talaei M,Pourmoghaddas Z,Sarrafzadegan N

更新日期：2012-01-01 00:00:00

abstract：:Type 2 diabetes is characterized by frequent ectopic fat accumulation in several tissues and organs. In particular, a number of studies showed that these subjects frequently have hepatic fat accumulation, which may play a role in the metabolic abnormalities typical of diabetes and has been also linked to increased ris...

journal_title：International journal of endocrinology

authors： Bacchi E,Moghetti P

更新日期：2013-01-01 00:00:00

abstract：:Background. Management of thyroid nodules with benign aspirates following atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) is not well established. We reviewed the risk of malignancy and the role of ultrasound (US) features among thyroid nodules with benign results followin...

journal_title：International journal of endocrinology

authors： Kim GR,Yoon JH,Kim EK,Moon HJ,Kwak JY

更新日期：2014-01-01 00:00:00

abstract：:Neurofibromatosis type 1 (NF1) patients are more likely to have vitamin D deficiency when compared to the general population. This study aimed to determine the levels of 25-OH-vitamin D [25(OH)D] in individuals with NF1 and disease-unaffected controls and analyze FokI and BsmI VDR gene polymorphisms in a case and in a...

journal_title：International journal of endocrinology

authors： Souza Mario Bueno L,Rosset C,Aguiar E,Pereira Fde S,Izetti Ribeiro P,Scalco R,Matzenbacher Bittar C,Brinckmann Oliveira Netto C,Gischkow Rucatti G,Chies JA,Camey SA,Ashton-Prolla P

更新日期：2015-01-01 00:00:00

abstract：:This study investigated potential markers for predicting nonfunctioning pituitary adenoma (NFPA) invasion and recurrence by high-throughput tissue microarray analyses. We retrospectively studied two groups of patients: 60 nonrecurrent NFPA cases that included noninvasion and invasion subtypes and 43 recurrent cases th...

journal_title：International journal of endocrinology

authors： Yao X,Zhang Y,Wu L,Cheng R,Li C,Qu C,Ji H

更新日期：2019-05-16 00:00:00

abstract：:The complementary role of hyperglycemia and p27(kip1) suppression on islet beta cell regeneration was investigated in a syngeneic mouse model. p27(kip1) gene silencing was performed by infecting islets of C57BL/6 with shRNA lentiviral particles. At 54 hours after viral infection, p27(kip1) protein content in cultured ...

journal_title：International journal of endocrinology

authors： Chen ST,Fu SH,Hsu S,Huang YY,Hsu BR

更新日期：2012-01-01 00:00:00

abstract：:Epidemiological studies have shown an association between short or disrupted sleep and an increased risk for metabolic disorders. To assess a possible causal relationship, we examined the effects of experimental sleep disturbance on glucose regulation in Wistar rats under controlled laboratory conditions. Three groups...

journal_title：International journal of endocrinology

authors： Barf RP,Meerlo P,Scheurink AJ

更新日期：2010-01-01 00:00:00

abstract：:Stevia rebaudiana (Bert.) Bertoni besides being a source of noncaloric sweeteners is also an important source of bioactive molecules. Many plant extracts, mostly obtained with ethyl acetate solvent, are rich in polyphenol compounds that present insulinotropic effects. To investigate whether the nonsweetener fraction, ...

journal_title：International journal of endocrinology

authors： Piovan S,Pavanello A,Peixoto GML,Matiusso CCI,de Moraes AMP,Martins IP,Malta A,Palma-Rigo K,da Silva Franco CC,Milani PG,Dacome AS,da Costa SC,de Freitas Mathias PC,Mareze-Costa CE

更新日期：2018-04-29 00:00:00

abstract：:HDL cholesterol is known to be inversely correlated with cardiovascular disease due to its diverse antiatherogenic functions. SR-BI mediates the selective uptake of HDL-C. SR-BI knockout diminishes but does not completely block the transport of HDL; other receptors may be involved. Ectopic ATP synthase β-chain in hepa...

journal_title：International journal of endocrinology

authors： Song K,Han Y,Zhang L,Liu G,Yang P,Cheng X,Bu L,Sheng H,Qu S

更新日期：2014-01-01 00:00:00

abstract：:The hypothalamus is an essential relay in the neural circuitry underlying energy metabolism that needs to continually adapt to changes in the energetic environment. The neuroendocrine control of food intake and energy expenditure is associated with, and likely dependent upon, hypothalamic plasticity. Severe disturbanc...

journal_title：International journal of endocrinology

authors： Stranahan AM,Martin B,Chadwick W,Park SS,Wang L,Becker KG,Woodiii WH,Zhang Y,Maudsley S

更新日期：2012-01-01 00:00:00

abstract：:Clinical evidences have highlighted the efficacy of myo-inositol and selenium in the treatment of autoimmune thyroiditis. Aim of this study was to further analyze the role of myo-inositol plus selenium (Myo-Ins-Se) in restoring a normal thyroid function of Hashimoto's patients with subclinical hypothyroidism. Eighty-s...

journal_title：International journal of endocrinology

authors： Nordio M,Basciani S

更新日期：2017-01-01 00:00:00

abstract：:Fibroblast growth factor 21 (FGF21) modulates a diverse range of biological functions, including glucose and lipid metabolism, adaptive starvation response, and energy homeostasis, but with limited mechanistic insight. FGF21 treatment has been shown to inhibit hepatic growth hormone (GH) intracellular signaling. To ev...

journal_title：International journal of endocrinology

authors： Boparai RK,Arum O,Miquet JG,Masternak MM,Bartke A,Khardori RK

更新日期：2015-01-01 00:00:00