Chronic sleep disturbance impairs glucose homeostasis in rats.

abstract：Objectives:To compare the predictive ability of six anthropometric indices for identification of metabolic syndrome (MetS) and to determine their optimal cut-off points among Chinese adults. Methods:A total of 59,029 participants were enrolled. Body mass index (BMI), waist circumference (WC), waist-to-height ratio (WH...

journal_title：International journal of endocrinology

authors： Zhang J,Zhu W,Qiu L,Huang L,Fang L

更新日期：2018-09-17 00:00:00

abstract：:Fibroblast growth factor 21 (FGF21) modulates a diverse range of biological functions, including glucose and lipid metabolism, adaptive starvation response, and energy homeostasis, but with limited mechanistic insight. FGF21 treatment has been shown to inhibit hepatic growth hormone (GH) intracellular signaling. To ev...

journal_title：International journal of endocrinology

authors： Boparai RK,Arum O,Miquet JG,Masternak MM,Bartke A,Khardori RK

更新日期：2015-01-01 00:00:00

abstract：:Hypogonadotropic hypogonadism (HH) can be sustained by organic or functional alterations of the hypothalamic-pituitary-testicular axis. Functional HH is related to systemic alterations, such as obesity or chronic inflammatory diseases, but could contribute to a negative course of the illness. For such situation, accor...

journal_title：International journal of endocrinology

authors： Giagulli VA,Silvestrini A,Bruno C,Triggiani V,Mordente A,Mancini A

更新日期：2020-01-21 00:00:00

abstract：:Background. Reduced testicular volume (TV) (<12 cm(3)) is associated with lower testicular function. Several studies explored the conventional sperm parameters (concentration, motility, and morphology) and the endocrine function (gonadotropins and testosterone serum concentrations) in the patients with reduction of TV...

journal_title：International journal of endocrinology

authors： Condorelli R,Calogero AE,La Vignera S

更新日期：2013-01-01 00:00:00

abstract：Objective:Selenium, as an antioxidant, has been implicated in the development of autoimmune thyroiditis (AIT). Many studies showed selenium supplementation could decrease thyroid autoantibodies in patients with AIT. However, the underlying mechanisms have not been well determined. Therefore, we performed a clinical stu...

journal_title：International journal of endocrinology

authors： Tian X,Li N,Su R,Dai C,Zhang R

更新日期：2020-06-30 00:00:00

abstract：:Enucleation-induced adrenal regeneration is a highly controlled process; however, only some elements involved in this process have been recognized. Therefore, we performed studies on regenerating rat adrenals. Microarray RNA analysis and QPCR revealed that enucleation resulted in a rapid elevation of expression of gen...

journal_title：International journal of endocrinology

authors： Tyczewska M,Rucinski M,Ziolkowska A,Szyszka M,Trejter M,Hochol-Molenda A,Nowak KW,Malendowicz LK

更新日期：2014-01-01 00:00:00

abstract：:Objective. In pediatric central diabetes insipidus (CDI), etiology diagnosis and pituitary function monitoring are usually delayed. This study aimed to illustrate the importance of regular follow-up and pituitary function monitoring in pediatric CDI. Methods. The clinical, hormonal, and neuroradiological characteristi...

journal_title：International journal of endocrinology

authors： Liu W,Wang L,Liu M,Li G

更新日期：2016-01-01 00:00:00

abstract：:Bariatric surgery is currently the most effective therapy to induce weight loss in morbidly obese patients. Objective. This controlled, clinical trial with a two-year intervention was aimed at comparing the efficacy of two nonsurgical approaches versus bariatric surgery, on body weight changes and metabolic parameters...

journal_title：International journal of endocrinology

authors： Burguera B,Jesús Tur J,Escudero AJ,Alos M,Pagán A,Cortés B,González XF,Soriano JB

更新日期：2015-01-01 00:00:00

abstract：:Sunlight-induced vitamin D, synthesis in the skin is the major source of vitamin D, but data on the relationship of sun-related behaviour with vitamin D and parathyroid hormone (PTH) levels are relatively sparse. We evaluated whether habitual sun exposure is associated with 25-hydroxyvitamin D (25[OH]D) and PTH levels...

journal_title：International journal of endocrinology

authors： Pilz S,Kienreich K,Stückler D,Meinitzer A,Tomaschitz A

更新日期：2012-01-01 00:00:00

abstract：:Objective. To examine the association of three most common obesity measures including body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR) with chronic kidney disease (CKD) risk in patients with type 2 diabetes mellitus (T2D). Design. Cross-sectional evaluation of the effect of anthropometric ...

journal_title：International journal of endocrinology

authors： Xu L,Yu W,Huang P,Li C,Li Y,Wang M,Xu Q,Wang J,Zheng C,Qu B,Zhao Y,Niu M,Wang O,Gong F

更新日期：2015-01-01 00:00:00

abstract：:Type 2 diabetes mellitus (T2D) is a disorder of glucose metabolism. It is a complex process involving the regulation of insulin secretion, insulin sensitivity, gluconeogenesis, and glucose uptake at the cellular level. Diabetic peripheral neuropathy (DPN) is one of the debilitating complications that is present in app...

journal_title：International journal of endocrinology

authors： Prabodha LBL,Sirisena ND,Dissanayake VHW

更新日期：2018-03-15 00:00:00

abstract：:A considerable increase in endocrine abnormalities has been reported over the last few decades worldwide. A growing exposure to endocrine-disrupting chemicals (EDCs) can be one of the causes of endocrine disorders in populations, and these disorders are not only restricted to the metabolic hormone system but can also ...

journal_title：International journal of endocrinology

authors： de Oliveira M,Rodrigues BM,Olimpio RMC,Graceli JB,Gonçalves BM,Costa SMB,da Silva TM,De Sibio MT,Moretto FCF,Mathias LS,Cardoso DBM,Tilli HP,Freitas-Lima LC,Nogueira CR

更新日期：2019-04-17 00:00:00

abstract：:Background. Separate lines of research have shown that menstrual cycling and contextual factors such as the gender of research personnel influence experimental pain reporting. Objectives. This study examines how brief, procedural interactions with female and male experimenters can affect experimentally reported pain (...

journal_title：International journal of endocrinology

authors： Vigil JM,DiDomenico J,Strenth C,Coulombe P,Kruger E,Mueller AA,Guevara Beltran D,Adams I

更新日期：2015-01-01 00:00:00

abstract：:Sestrin (SESN) is known as a cysteine sulfinic acid reductase. Recently, nonredox functions of SESN in metabolic regulation and antitumor property have been recognized. While mechanisms underlying the expression of SESN are not fully understood. Here we report that insulin markedly increased SESN2 level in HepG2 cells...

journal_title：International journal of endocrinology

authors： Chai D,Wang G,Zhou Z,Yang H,Yu Z

更新日期：2015-01-01 00:00:00

abstract：Objective:To identify the clinicopathological features correlated to lymph node metastasis (LNM) in patients with papillary thyroid microcarcinoma (PTMC). Methods:Clinical data of 785 PTMC patients who underwent surgical treatment at the Lishui Municipal Central Hospital from September 2008 to December 2017 were retro...

journal_title：International journal of endocrinology

authors： Cheng F,Chen Y,Zhu L,Zhou B,Xu Y,Chen Y,Wen L,Chen S

更新日期：2019-01-15 00:00:00

abstract：:To investigate effects of long-term testosterone (T) therapy in obese men with T deficiency (TD) and type 2 diabetes mellitus (T2DM), data were collected from two observational, prospective, and cumulative registry studies of 561 men with TD receiving T therapy for up to 6 years. A subgroup of obese hypogonadal men wi...

journal_title：International journal of endocrinology

authors： Haider A,Yassin A,Doros G,Saad F

更新日期：2014-01-01 00:00:00

abstract：:The risk for cardiovascular diseases and type 2 diabetes mellitus significantly increases in the patient population with metabolic syndrome (MeS). The present study aimed to investigate the association between the epicardial adipose tissue thickness (EATT) and the oxidative stress parameters in MeS patients. The study...

journal_title：International journal of endocrinology

authors： Demir B,Demir E,Acıksarı G,Uygun T,Utku IK,Gedikbasi A,Caglar IM,Pirhan O,Tureli HO,Oflar E,Ungan İ,Ciftci S,Karakaya O

更新日期：2014-01-01 00:00:00

abstract：:In the last 20 years, a pituitary-hypothalamus tissue culture system with intact neural and portal connections has been developed in our lab and used to understand the feedback mechanisms that regulate the secretions of adenohypophyseal hormones and fertility of male rats. In the last decade, several in vivo rat model...

journal_title：International journal of endocrinology

authors： Gill-Sharma MK

更新日期：2009-01-01 00:00:00

abstract：:The increased prevalence of obesity represents, currently, one of the major public health issues, due to its consequences on physical and psychological health status as well as on the psychosocial functioning. As defined by the World Health Organization, sexual health is "a state of physical, emotional, mental, and so...

journal_title：International journal of endocrinology

authors： Poggiogalle E,Di Lazzaro L,Pinto A,Migliaccio S,Lenzi A,Donini LM

更新日期：2014-01-01 00:00:00

abstract：:Pancreatic beta-cells, which secrete the hormone insulin, are the key arbiters of glucose homeostasis. Defective beta-cell numbers and/or function underlie essentially all major forms of diabetes and must be restored if diabetes is to be cured. Thus, the identification of the molecular regulators of beta-cell mass and...

journal_title：International journal of endocrinology

authors： Tarabra E,Pelengaris S,Khan M

更新日期：2012-01-01 00:00:00

abstract：:The study aimed at assessing the potential use of lower total and HMW adiponectin levels for predicting cardiovascular risk in patients with type 2 diabetes mellitus (T2DM). Concentrations of total adiponectin or high molecular weight (HMW) adiponectin decrease in association with the development of metabolic dysfunct...

journal_title：International journal of endocrinology

authors： Horáková D,Azeem K,Benešová R,Pastucha D,Horák V,Dumbrovská L,Martínek A,Novotný D,Švagera Z,Hobzová M,Galuszková D,Janout V,Doněvská S,Vrbková J,Kollárová H

更新日期：2015-01-01 00:00:00

abstract：Background:Type 2 diabetes mellitus is a serious public health problem worldwide. Accumulating evidence has shown that β-cell dysfunction is an important mechanism underlying diabetes mellitus. The changes in the physiological state of islet stellate cells (ISCs) and the effects of these cells on β-cell dysfunction is ...

journal_title：International journal of endocrinology

authors： Xu W,Jones PM,Geng H,Li R,Liu X,Li Y,Lv Q,Liu Y,Wang J,Wang X,Sun Z,Liang J

更新日期：2020-02-24 00:00:00

abstract：:Iodine supplementation through salt iodization is a worldwide, effective strategy for preventing iodine deficiency-related problems. Its safety and efficacy profile has been extensively investigated, and benefits far outweigh the potential iodine-induced risks. Moreover, iodine supplementation during pregnancy in orde...

journal_title：International journal of endocrinology

authors： Prete A,Paragliola RM,Corsello SM

更新日期：2015-01-01 00:00:00

abstract：:Background. The purpose of the present study was to assess the feasibility of using miR-126 in the urine as a biomarker for diabetic nephropathy. Methods. miRNAs were extracted from the urine samples of T2DM patients with diabetic nephropathy (DN; n = 92), T2DM without DN (n = 86), and 85 healthy volunteers using quan...

journal_title：International journal of endocrinology

authors： Liu Y,Gao G,Yang C,Zhou K,Shen B,Liang H,Jiang X

更新日期：2014-01-01 00:00:00

abstract：Background:Insulin promotes glucose consumption as the main cardiac energy source, while increasing myocardial efficiency. The short-term effects of insulin on cardiac function and its potential curative role in an acute diabetological cardiology setting remain unknown. Our study evaluated the role of acute insulin adm...

journal_title：International journal of endocrinology

authors： Daoud Naccache D,Yalonetsky S,Bar-Yoseph R

更新日期：2020-03-17 00:00:00

abstract：:There is inconsistency among published guidelines for the optimal diagnostic and management pathways for patients with typical (TC) or atypical (AC) pulmonary carcinoid tumours. We conducted a UK-wide clinician survey to assess current practice for the diagnosis, management, and follow-up of patients with TC/AC and de...

journal_title：International journal of endocrinology

authors： Mansoor W,Ferguson S,Ross V,Talbot D

更新日期：2020-02-28 00:00:00

abstract：:The objective of this cross-sectional study was to assess differences in the control and treatment of modifiable cardiovascular risk factors (CVRF: HbA1c, blood pressure [BP], LDL-cholesterol, body mass index, and smoking habit) according to gender and the presence of cardiovascular disease (CVD) in patients with type...

journal_title：International journal of endocrinology

authors： Franch-Nadal J,Mata-Cases M,Vinagre I,Patitucci F,Hermosilla E,Casellas A,Bolivar B,Mauricio D

更新日期：2014-01-01 00:00:00

abstract：:Aim. Our aim was (1) to determine the frequency of insulin resistance (IR) in patients with Duchenne/Becker muscular dystrophy (DMD/BMD), (2) to identify deleted exons of DMD gene associated with obesity and IR, and (3) to explore some likely molecular mechanisms leading to IR. Materials and Methods. In 66 patients wi...

journal_title：International journal of endocrinology

authors： Rodríguez-Cruz M,Sanchez R,Escobar RE,Cruz-Guzmán Odel R,López-Alarcón M,Bernabe García M,Coral-Vázquez R,Matute G,Velázquez Wong AC

更新日期：2015-01-01 00:00:00

abstract：Background:The purpose of the current study is to determine PTH reference values in vitamin-D-replete Lebanese adults using 2nd and 3rd generation PTH assays and to look at the factors that affect PTH variations. Methods:Fasting PTH was measured using 2nd and 3rd generation Diasorin PTH assays in 339 vitamin-D-replete...

journal_title：International journal of endocrinology

authors： Gannagé-Yared MH,Kallas-Chémaly MN,Sleilaty G

更新日期：2020-02-21 00:00:00

abstract：:Glucose is the major source of energy for the human brain which in turn uses ketone bodies as a supplement for energy deficit in glucose cell deficiency conditions. Pregnancy complicated by gestational diabetes is a condition associated with significantly increased risk of ketonemia development. The data available pro...

journal_title：International journal of endocrinology

authors： Bronisz A,Ozorowski M,Hagner-Derengowska M

更新日期：2018-06-04 00:00:00