Abstract:
Objective:To identify the clinicopathological features correlated to lymph node metastasis (LNM) in patients with papillary thyroid microcarcinoma (PTMC). Methods:Clinical data of 785 PTMC patients who underwent surgical treatment at the Lishui Municipal Central Hospital from September 2008 to December 2017 were retrospectively analyzed. Clinical and pathological risk factors for lymph node metastasis (LNM), central lymph node metastasis (CLNM), and lateral lymph node metastasis (LLNM) were analyzed. Results:LNM was found in 236 (30.2%) patients. Multivariate logistic regression analysis revealed that in PTMC, male gender, age < 55 years, tumor size > 5 mm, bilateral lesions, and extrathyroidal extension were independent risk factors for LNM in general and for CLNM. For LLNM, tumor size > 5 mm, multifocal lesions, and extrathyroidal extension were independent risk factors. Conclusions:Identification of risk factors for cervical LNM could assist individualization of clinical management for PTMC.
journal_name
Int J Endocrinoljournal_title
International journal of endocrinologyauthors
Cheng F,Chen Y,Zhu L,Zhou B,Xu Y,Chen Y,Wen L,Chen Sdoi
10.1155/2019/8579828subject
Has Abstractpub_date
2019-01-15 00:00:00pages
8579828eissn
1687-8337issn
1687-8345journal_volume
2019pub_type
杂志文章abstract::To examine the gene expression of ghrelin, a growth hormone releasing and appetite stimulating hormone from stomach, we constructed human ghrelin promoter-reporter vectors and analyzed the promoter activity. The ghrelin promoter activity was high when cultured cells that express ghrelin mRNA endogenously like TT or EC...
journal_title:International journal of endocrinology
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journal_title:International journal of endocrinology
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journal_title:International journal of endocrinology
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journal_title:International journal of endocrinology
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pub_type: 杂志文章,评审
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更新日期:2018-10-02 00:00:00
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journal_title:International journal of endocrinology
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