Abstract:
:From January 1987 to December 2011, over a total of 25 years, 84 patients with Cushing's syndrome (CS) were identified at a medical center in southern Taiwan. We observed a higher incidence of ACTH-independent CS (75%) than ACTH-dependent CS (25%). A higher incidence of adrenocortical adenoma (58.3%) than Cushing's disease (CD, 21.4%) was also found. The sensitivity of the definitive diagnostic tests for CS, including loss of plasma cortisol circadian rhythm, a baseline 24 h urinary free cortisol (UFC) value >80 μ g, and overnight and 2-day low-dose dexamethasone suppression test, was between 94.4% and 100%. For the 2-day high-dose dexamethasone suppression test for the differential diagnosis of CD, the sensitivity of 0800 h plasma cortisol and 24 h UFC was 44.4% and 85.7%, respectively. For the differential diagnosis of adrenal CS, the sensitivities of the 0800 h plasma cortisol and 24 h UFC were 95.5% and 88.9%, respectively. In patients with ACTH-independent CS and ACTH-dependent CS, the baseline plasma ACTH levels were all below 29 pg/mL and above 37 pg/mL, respectively. The postsurgical hospitalization stay following retroperitoneoscopic adrenalectomy was shorter than that observed for transabdominal adrenalectomy (4.3 ± 1.6 versus 8.8 ± 3.7 days, P < 0.001). It was easy to develop retroperitoneal and peritoneal seeding of adrenocortical carcinoma via laparoscopic adrenalectomy.
journal_name
Int J Endocrinoljournal_title
International journal of endocrinologyauthors
Tung SC,Wang PW,Liu RT,Chen JF,Hsieh CJ,Kuo MC,Yang JW,Lee WC,Cheng MH,Lee TCdoi
10.1155/2013/685375subject
Has Abstractpub_date
2013-01-01 00:00:00pages
685375eissn
1687-8337issn
1687-8345journal_volume
2013pub_type
杂志文章abstract:Background:Little information is available on the association between parents' metabolic syndrome (MetS) and adolescent offspring's obesity in Korea. The aim of our study is to determine the association between parent's metabolic syndrome and offspring's obesity. Methods:The study data were obtained from the Korean Na...
journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2020/8737912
更新日期:2020-10-30 00:00:00
abstract::In the last decade, miRNAs have received substantial attention as potential players of diabetes microvascular complications, affecting the kidney, the retina, and the peripheral neurons. Compelling evidence indicates that abnormally expressed miRNAs have pivotal roles in key pathogenic processes of microvascular compl...
journal_title:International journal of endocrinology
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journal_title:International journal of endocrinology
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更新日期:2016-01-01 00:00:00
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journal_title:International journal of endocrinology
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journal_title:International journal of endocrinology
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journal_title:International journal of endocrinology
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doi:10.1155/2012/379097
更新日期:2012-01-01 00:00:00
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journal_title:International journal of endocrinology
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更新日期:2019-04-07 00:00:00
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journal_title:International journal of endocrinology
pub_type: 杂志文章
doi:10.1155/2012/732975
更新日期:2012-01-01 00:00:00
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journal_title:International journal of endocrinology
pub_type: 杂志文章,评审
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更新日期:2014-01-01 00:00:00
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