Islet Stellate Cells Regulate Insulin Secretion via Wnt5a in Min6 Cells.

abstract：:Background. Oxidative stress induced by reactive oxygen and nitrogen species is critically involved in the impairment of β -cell function during the development of diabetes. Methods. HIT-T15 cells were cultured in 5% CO2 and then preincubated with Gelam honey extracts (20, 40, 60, and 80 µg/mL) as well as quercetin (2...

journal_title：International journal of endocrinology

authors： Batumalaie K,Zaman Safi S,Mohd Yusof K,Shah Ismail I,Devi Sekaran S,Qvist R

更新日期：2013-01-01 00:00:00

abstract：:Objective. To explore whether GC (group-specific component) rs17467825, rs4588, and rs7041 polymorphisms are associated with generalized aggressive periodontitis. Methods. This case-control study recruited 372 patients with generalized aggressive periodontitis (group AgP) and 133 periodontal healthy subjects (group HP...

journal_title：International journal of endocrinology

authors： Song W,Wang X,Tian Y,Zhang X,Lu R,Meng H

更新日期：2016-01-01 00:00:00

abstract：:Background. Papillary thyroid cancer (PTC) exhibits a higher incidence in women. Due to various ages at menarche and menopause, estrogen levels vary, which may account for the differences in the occurrence, development, and prognosis of female patients with PTC. Objective. The aim of this study was to investigate the ...

journal_title：International journal of endocrinology

authors： Zhu X,Yu B,Huang YQ,Zhou JN,Ge MH

更新日期：2017-01-01 00:00:00

abstract：:Point-of-care (POC) glucose technology is currently considered to be insufficiently accurate for the diagnosis of diabetes. The objective of this study was to investigate the diagnostic accuracy of an innovative, interference-resistant POC glucose meter (StatStrip glucose hospital meter, Nova Biomedical, USA) in subje...

journal_title：International journal of endocrinology

authors： Vučić Lovrenčić M,Radišić Biljak V,Božičević S,Pape-Medvidović E,Ljubić S

更新日期：2013-01-01 00:00:00

abstract：Aims:Emerging evidence has suggested a mechanistic link from vitamin D metabolism to glucose and insulin homeostasis. This study is aimed at specifically quantifying the direct effects of vitamin D supplementation on indexes of glucose and insulin homeostasis as well as incidence of type 2 diabetes (T2D) among nondiabe...

journal_title：International journal of endocrinology

authors： Tang H,Li D,Li Y,Zhang X,Song Y,Li X

更新日期：2018-12-03 00:00:00

abstract：:Sunlight-induced vitamin D, synthesis in the skin is the major source of vitamin D, but data on the relationship of sun-related behaviour with vitamin D and parathyroid hormone (PTH) levels are relatively sparse. We evaluated whether habitual sun exposure is associated with 25-hydroxyvitamin D (25[OH]D) and PTH levels...

journal_title：International journal of endocrinology

authors： Pilz S,Kienreich K,Stückler D,Meinitzer A,Tomaschitz A

更新日期：2012-01-01 00:00:00

abstract：:We investigated the role of urokinase plasminogen activator (uPA) and its soluble receptors (suPAR) and plasminogen activator inhibitor-1 (PAI-1) in metabolic syndrome (MetS) components, insulin secretion, and resistance in schoolchildren. We enrolled 387 children, aged 10.3 ± 1.5 years, in Taipei. Anthropometry, fibr...

journal_title：International journal of endocrinology

authors： Chen JS,Wu CZ,Chu NF,Chang LC,Pei D,Lin YF

更新日期：2015-01-01 00:00:00

abstract：Introduction:Obesity has an unclear pathogenesis. MicroRNAs (miRNAs) may function as biologically active molecules for obesity through regulating adipocyte differentiation. This study aimed to identify how miR-129-5p (a specific miRNA) regulates adipogenesis in vitro and explore its possible role in the pathogenesis of...

journal_title：International journal of endocrinology

authors： Fu X,Jin L,Han L,Yuan Y,Mu Q,Wang H,Yang J,Ning G,Zhou D,Zhang Z

更新日期：2019-11-06 00:00:00

abstract：BACKGROUND:Evidence on the association between subclinical thyroid dysfunction and the risk of cardiovascular outcomes are conflicting. METHODS AND RESULTS:PubMed, EMbase, Web of Science, Cochrane Library, and China Biology Medicine (CBM) databases were searched from inception to July 10, 2016. A total of 16 studies w...

journal_title：International journal of endocrinology

authors： Sun J,Yao L,Fang Y,Yang R,Chen Y,Yang K,Tian L

更新日期：2017-01-01 00:00:00

abstract：:Estroprogestins (EPs) are combinations of estrogen and progestin with several actions on women's health. The different pharmacological composition of EPs is responsible for different clinical effects. One of the most used low-dose EP associations is ethinylestradiol 20 mcg plus levonorgestrel 100 mcg in monophasic reg...

journal_title：International journal of endocrinology

authors： Lello S,Cavani A

更新日期：2014-01-01 00:00:00

abstract：:Prostate cancer (PCa) is the most common malignancy in elderly men. The progressive ageing of the world male population will further increase the need for tailored assessment and treatment of PCa patients. The determinant role of androgens and sexual hormones for PCa growth and progression has been established. Howeve...

journal_title：International journal of endocrinology

authors： Gacci M,Baldi E,Tamburrino L,Detti B,Livi L,De Nunzio C,Tubaro A,Gravas S,Carini M,Serni S

更新日期：2014-01-01 00:00:00

abstract：:The determination of B-type natriuretic peptides (BNP) may have a role in the diagnosis of heart failure (HF) or guiding HF therapy. This study investigated the role of BNP determination in a cohort of elderly patients admitted to hospital with acute decompensated HF and its correlation with main demographic, clinical...

journal_title：International journal of endocrinology

authors： Leto L,Testa M,Feola M

更新日期：2015-01-01 00:00:00

abstract：:Fibroblast growth factor 21 (FGF21) modulates a diverse range of biological functions, including glucose and lipid metabolism, adaptive starvation response, and energy homeostasis, but with limited mechanistic insight. FGF21 treatment has been shown to inhibit hepatic growth hormone (GH) intracellular signaling. To ev...

journal_title：International journal of endocrinology

authors： Boparai RK,Arum O,Miquet JG,Masternak MM,Bartke A,Khardori RK

更新日期：2015-01-01 00:00:00

abstract：Objective:Atypical parathyroid adenoma is a rare neoplasm, showing atypical histological features intermediate between classic benign adenoma and the rarest parathyroid carcinoma, whose the clinical behaviour and outcome is not yet understood or predictable. Up to date only two cases of atypical adenoma were found asso...

journal_title：International journal of endocrinology

authors： Cinque L,Pugliese F,Clemente C,Castellana S,Leone MP,de Martino D,Balsamo T,Battista C,Biagini T,Graziano P,Castori M,Scillitani A,Guarnieri V

更新日期：2020-04-27 00:00:00

abstract：:Background. Abdominal obesity and its relative distribution are known to differ in association with metabolic characteristics and cardiorespiratory fitness. This study aimed to determine an association between fitness level and abdominal adiposity in overweight and obese adults. Methods. 228 overweight and obese indiv...

journal_title：International journal of endocrinology

authors： Kim S,Kim JY,Lee DC,Lee HS,Lee JW,Jeon JY

更新日期：2014-01-01 00:00:00

abstract：:Oxidized low density lipoprotein (ox-LDL) is a product of oxidative stress. In this cross-sectional study, we compared the ox-LDL concentrations in diabetic patients with normoalbuminuria (n = 28), microalbuminuria (n = 28), and macroalbuminuria (n = 28) with their first degree relatives (n = 28) and healthy control p...

journal_title：International journal of endocrinology

authors： Behzadi P,Torabi F,Amini M,Aminorroaya A

更新日期：2012-01-01 00:00:00

abstract：:Introduction. The mechanisms underlying the association between insulin resistance and intrahepatic lipid (IHL) accumulation are not completely understood. We sought to determine whether this association was explained by differences in fasting non-esterified fatty acid (NEFA) levels and/or NEFA suppression after oral ...

journal_title：International journal of endocrinology

authors： Finucane FM,Sharp SJ,Hatunic M,Sleigh A,De Lucia Rolfe E,Sayer AA,Cooper C,Griffin SJ,Savage DB,Wareham NJ

更新日期：2013-01-01 00:00:00

abstract：:Preeclampsia is a serious medical problem affecting the mother and her child and influences their health not only during the pregnancy, but also many years after. Although preeclampsia is a subject of many research projects, the etiology of the condition remains unclear. One of the hypotheses related to the etiology o...

journal_title：International journal of endocrinology

authors： Kosicka K,Siemiątkowska A,Główka FK

更新日期：2016-01-01 00:00:00

abstract：:Parathyroid carcinoma (PC) is a rare disease responsible for about 1% of primary hyperparathyroidism (PHPT) cases. PC usually has an indolent course, tough to differentiate from the benign causes of PHPT, and the only certain diagnosis is histologic. The gold standard surgical treatment is the en bloc resection associ...

journal_title：International journal of endocrinology

authors： Quaglino F,Manfrino L,Cestino L,Giusti M,Mazza E,Piovesan A,Palestini N,Lauro C,Castellano E

更新日期：2020-03-06 00:00:00

abstract：:Glucose is the major source of energy for the human brain which in turn uses ketone bodies as a supplement for energy deficit in glucose cell deficiency conditions. Pregnancy complicated by gestational diabetes is a condition associated with significantly increased risk of ketonemia development. The data available pro...

journal_title：International journal of endocrinology

authors： Bronisz A,Ozorowski M,Hagner-Derengowska M

更新日期：2018-06-04 00:00:00

abstract：:The circadian system is a supraphysiological system that modulates different biological functions such as metabolism, sleep-wake, cellular proliferation, and body temperature. Different chronodisruptors have been identified, such as shift work, feeding time, long days, and stress. The environmental changes and our mod...

journal_title：International journal of endocrinology

authors： Valenzuela FJ,Vera J,Venegas C,Muñoz S,Oyarce S,Muñoz K,Lagunas C

更新日期：2016-01-01 00:00:00

abstract：:Sestrin (SESN) is known as a cysteine sulfinic acid reductase. Recently, nonredox functions of SESN in metabolic regulation and antitumor property have been recognized. While mechanisms underlying the expression of SESN are not fully understood. Here we report that insulin markedly increased SESN2 level in HepG2 cells...

journal_title：International journal of endocrinology

authors： Chai D,Wang G,Zhou Z,Yang H,Yu Z

更新日期：2015-01-01 00:00:00

abstract：:The goal of this study was to determine the prevalence and associated risk factors of impaired glucose regulation (IGR) in the population of Tongzhou, China, and to provide scientific basis for preventive interventions. In the study, the overall age-standardized prevalence of IGR (16.0%) in Tongzhou residents was high...

journal_title：International journal of endocrinology

authors： Zhao D,Wu N,Yang J,Liu S,Zhang N,Wang X,Zhang H

更新日期：2015-01-01 00:00:00

abstract：Purpose:Hyperoside, a flavonoid isolated from conventional medicinal herbs, has been demonstrated to exert a significant protective effect in diabetic nephropathy. This study aimed to determine the underlying mechanisms, by which hyperoside inhibits high glucose-(HG-) induced proliferation in mouse renal mesangial cell...

journal_title：International journal of endocrinology

authors： Zhang L,Dai Q,Hu L,Yu H,Qiu J,Zhou J,Long M,Zhou S,Zhang K

更新日期：2020-07-21 00:00:00

abstract：:Thyroid function and microalbuminuria are both associated with vascular disease and endothelial damage. However, whether thyroid function is associated with microalbuminuria is not well established. The objective was to explore the relationship between thyroid hormones and microalbuminuria in Chinese population. A com...

journal_title：International journal of endocrinology

authors： Zhou Y,Ye L,Wang T,Hong J,Bi Y,Zhang J,Xu B,Sun J,Huang X,Xu M

更新日期：2014-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2014/690783.]. ...

journal_title：International journal of endocrinology

authors： Napoli N,Strollo R,Paladini A,Briganti SI,Pozzilli P,Epstein S

更新日期：2017-01-01 00:00:00

abstract：:The study aimed at assessing the potential use of lower total and HMW adiponectin levels for predicting cardiovascular risk in patients with type 2 diabetes mellitus (T2DM). Concentrations of total adiponectin or high molecular weight (HMW) adiponectin decrease in association with the development of metabolic dysfunct...

journal_title：International journal of endocrinology

authors： Horáková D,Azeem K,Benešová R,Pastucha D,Horák V,Dumbrovská L,Martínek A,Novotný D,Švagera Z,Hobzová M,Galuszková D,Janout V,Doněvská S,Vrbková J,Kollárová H

更新日期：2015-01-01 00:00:00

abstract：:Polycystic ovary syndrome (PCOS) is the most common endocrine disorder amongst women of reproductive age. Although PCOS is diagnosed exclusively based on reproductive criteria, it is also a metabolic disorder. Insulin resistance, impaired glucose tolerance, type 2 diabetes mellitus, obesity, and dyslipidemia are more ...

journal_title：International journal of endocrinology

authors： Baldani DP,Skrgatic L,Ougouag R

更新日期：2015-01-01 00:00:00

abstract：:The aim of this work was to study the androgen receptors (AR) expression in pituitary pars distalis (PD) of male viscachas in relation to growth and reproductive cycle. AR were detected by immunocytochemistry and quantified by image analysis. Pituitary glands from fetus, immature, prepubertal, and adult viscachas duri...

journal_title：International journal of endocrinology

authors： Filippa VP,Rosales GJ,Cruceño AA,Mohamed FH

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:We aimed to explore whether squamous cell carcinoma antigen (SCC), cytokeratin 19 fragment (Cyfra21-1), neuron-specific enolase (NSE), and carcinoembryonic antigen (CEA) are elevated in diabetic nephropathy (DN) and the association between urinary albumin-to-creatinine ratio (UACR) and tumor markers in diabet...

journal_title：International journal of endocrinology

authors： Chen J,Tao F,Zhang B,Chen Q,Qiu Y,Luo Q,Gen Y,Meng J,Zhang J,Lu H

更新日期：2017-01-01 00:00:00