Association among Fibrinolytic Proteins, Metabolic Syndrome Components, Insulin Secretion, and Resistance in Schoolchildren.

abstract：:Propylthiouracil- (PTU-) induced hepatotoxicity is rare but potentially lethal with a spectrum of liver injury ranging from asymptomatic elevation of transaminases to fulminant hepatic failure and death. We describe two cases of acute hepatic failure due to PTU that required liver transplantation. Differences in the c...

journal_title：International journal of endocrinology

authors： Carrion AF,Czul F,Arosemena LR,Selvaggi G,Garcia MT,Tekin A,Tzakis AG,Martin P,Ghanta RK

更新日期：2010-01-01 00:00:00

abstract：Introduction:Cushing's syndrome (CS) is a clinical condition characterized by excessive cortisol production, associated with metabolic complications, such as diabetes mellitus, dyslipidemia, metabolic syndrome, hypertension, and cardiovascular diseases. Nowadays, the occurrence of autoimmune diseases in CS have not bee...

journal_title：International journal of endocrinology

authors： Petramala L,Olmati F,Conforti MG,Concistré A,Bisogni V,Alfieri N,Iannucci G,de Toma G,Letizia C

更新日期：2018-12-18 00:00:00

abstract：:Peripheral neuropathy (PN) is a primary complication of type 2 diabetes mellitus (T2DM) and a direct manifestation of vitamin B12 deficiency. Examining the effects of metformin use on PN status became imperative following clinical studies that showed the vitamin B12-lowering effect of the medication. The complexity of...

journal_title：International journal of endocrinology

authors： Ahmed MA,Muntingh GL,Rheeder P

更新日期：2017-01-01 00:00:00

abstract：Background:Increased platelet response is seen in individuals with metabolic syndrome. Previous reports have shown that arginine supplementation and aerobic exercise training enhance vascular nitric oxide (NO) activity and inhibit platelet hyperaggregability; however, the effects of their association remain unknown. A...

journal_title：International journal of endocrinology

authors： Motta NAV,Fumian MM,Medeiros RF,Lima GF,Scaramello CBV,Oliveira KJ,Nóbrega ACL,Brito FCF

更新日期：2019-01-06 00:00:00

abstract：:Sestrin (SESN) is known as a cysteine sulfinic acid reductase. Recently, nonredox functions of SESN in metabolic regulation and antitumor property have been recognized. While mechanisms underlying the expression of SESN are not fully understood. Here we report that insulin markedly increased SESN2 level in HepG2 cells...

journal_title：International journal of endocrinology

authors： Chai D,Wang G,Zhou Z,Yang H,Yu Z

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Recent guidelines from the American Thyroid Association (ATA) indicate that, in many patients affected by differentiated thyroid cancer (DTC), the serum TSH should be maintained between 0.1 and 0.5 mU/L. The purpose of this study was to evaluate the TSH variability of patients affected by DTC treated with li...

journal_title：International journal of endocrinology

authors： Cappelli C,Pirola I,Gandossi E,Casella C,Lombardi D,Agosti B,Marini F,Delbarba A,Castellano M

更新日期：2017-01-01 00:00:00

abstract：Objective:Aim of this study is to evaluate determinants of secondary normocalcemic hyperparathyroidism (SNHPT) persistence in patients who have undergone Roux-en-Y gastric bypass on vertical-banded gastroplasty. Methods:226 consecutive patients submitted to bariatric surgery were prospectively enrolled and divided in ...

journal_title：International journal of endocrinology

authors： Casella C,Molfino S,Mittempergher F,Cappelli C,Portolani N

更新日期：2018-03-06 00:00:00

abstract：Objective:The aim of the present study was to investigate the association between dietary patterns and precocious puberty among Shanghai children. Methods:A cross-sectional study was conducted among Shanghai children by multistage stratified cluster random sampling in June 2014. Diet was assessed using a simplified fo...

journal_title：International journal of endocrinology

authors： Chen C,Chen Y,Zhang Y,Sun W,Jiang Y,Song Y,Zhu Q,Mei H,Wang X,Liu S,Jiang F

更新日期：2018-01-16 00:00:00

abstract：Objective:Atypical parathyroid adenoma is a rare neoplasm, showing atypical histological features intermediate between classic benign adenoma and the rarest parathyroid carcinoma, whose the clinical behaviour and outcome is not yet understood or predictable. Up to date only two cases of atypical adenoma were found asso...

journal_title：International journal of endocrinology

authors： Cinque L,Pugliese F,Clemente C,Castellana S,Leone MP,de Martino D,Balsamo T,Battista C,Biagini T,Graziano P,Castori M,Scillitani A,Guarnieri V

更新日期：2020-04-27 00:00:00

abstract：:The BRAF(V600E) mutation is commonly found in papillary thyroid cancers (PTCs) at different frequencies in different regions. However, the association between the BRAF(V600E) mutation and clinicopathological features in Chinese PTC patients is unknown. A total of 543 Chinese patients with histologically confirmed PTC ...

journal_title：International journal of endocrinology

authors： Yang LB,Sun LY,Jiang Y,Tang Y,Li ZH,Zhang HY,Bu H,Ye F

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Current study was designed to investigate the association of metabolic syndrome (MetS) with depression, anxiety, psychological distress, and quality of life (QoL). DESIGN:Two hundred and fifteen contributors with MetS and 253 participants without MetS were randomly selected from 2151 participants of Isfahan ...

journal_title：International journal of endocrinology

authors： Roohafza H,Sadeghi M,Talaei M,Pourmoghaddas Z,Sarrafzadegan N

更新日期：2012-01-01 00:00:00

abstract：Objectives:To compare the predictive ability of six anthropometric indices for identification of metabolic syndrome (MetS) and to determine their optimal cut-off points among Chinese adults. Methods:A total of 59,029 participants were enrolled. Body mass index (BMI), waist circumference (WC), waist-to-height ratio (WH...

journal_title：International journal of endocrinology

authors： Zhang J,Zhu W,Qiu L,Huang L,Fang L

更新日期：2018-09-17 00:00:00

abstract：:Leptin and adiponectin are differentially expressed adipokines in obesity and cardiovascular diseases. Leptin levels are directly associated with adipose tissue mass, while adiponectin levels are downregulated in obesity. Although significantly produced by adipocytes, leptin is also produced by vascular smooth muscle ...

journal_title：International journal of endocrinology

authors： Ghantous CM,Azrak Z,Hanache S,Abou-Kheir W,Zeidan A

更新日期：2015-01-01 00:00:00

abstract：:The aim of this work was to study the androgen receptors (AR) expression in pituitary pars distalis (PD) of male viscachas in relation to growth and reproductive cycle. AR were detected by immunocytochemistry and quantified by image analysis. Pituitary glands from fetus, immature, prepubertal, and adult viscachas duri...

journal_title：International journal of endocrinology

authors： Filippa VP,Rosales GJ,Cruceño AA,Mohamed FH

更新日期：2015-01-01 00:00:00

abstract：:Purpose. To evaluate whether inferior rectus muscle (IRM) thickness, the degree of adipose change in the IRM, smoking status, and the previous history of orbital radiotherapy can predict the dose-effect relationship regarding unilateral IRM recession in thyroid eye disease (TED). Methods. Twenty-five patients were ret...

journal_title：International journal of endocrinology

authors： Takahashi Y,Kakizaki H

更新日期：2015-01-01 00:00:00

abstract：:Endocannabinoids and their G-protein coupled receptors (GPCR) are a current research focus in the area of obesity due to the system's role in food intake and glucose and lipid metabolism. Importantly, overweight and obese individuals often have higher circulating levels of the arachidonic acid-derived endocannabinoids...

journal_title：International journal of endocrinology

authors： Naughton SS,Mathai ML,Hryciw DH,McAinch AJ

更新日期：2013-01-01 00:00:00

abstract：:Background. Oxidative stress induced by reactive oxygen and nitrogen species is critically involved in the impairment of β -cell function during the development of diabetes. Methods. HIT-T15 cells were cultured in 5% CO2 and then preincubated with Gelam honey extracts (20, 40, 60, and 80 µg/mL) as well as quercetin (2...

journal_title：International journal of endocrinology

authors： Batumalaie K,Zaman Safi S,Mohd Yusof K,Shah Ismail I,Devi Sekaran S,Qvist R

更新日期：2013-01-01 00:00:00

abstract：:Background. Papillary thyroid cancer (PTC) exhibits a higher incidence in women. Due to various ages at menarche and menopause, estrogen levels vary, which may account for the differences in the occurrence, development, and prognosis of female patients with PTC. Objective. The aim of this study was to investigate the ...

journal_title：International journal of endocrinology

authors： Zhu X,Yu B,Huang YQ,Zhou JN,Ge MH

更新日期：2017-01-01 00:00:00

abstract：:Background. Pediatric CAH patients have an increased risk of cardiovascular disease, and it remains unknown if genetic predisposition is a contributing factor. Glucocorticoid receptor gene (NR3C1) polymorphisms are associated with an adverse metabolic profile. Our aim was to analyze the association between the NR3C1 p...

journal_title：International journal of endocrinology

authors： Moreira RP,Gomes LG,Madureira G,Mendonca BB,Bachega TA

更新日期：2014-01-01 00:00:00

abstract：:Diabetes mellitus (DM) is one of the primary causes of premature death and disability worldwide. We performed a systematic review and meta-analysis of the published literature regarding the trends in prevalence, awareness, treatment, and control of diabetes mellitus in mainland China. PUBMED, EMBASE, Chinese Biomedica...

journal_title：International journal of endocrinology

authors： Li MZ,Su L,Liang BY,Tan JJ,Chen Q,Long JX,Xie JJ,Wu GL,Yan Y,Guo XJ,Gu L

更新日期：2013-01-01 00:00:00

abstract：:The presence of brown adipose tissue (BAT) in humans is unclear. Pheochromocytomas (PHEO) are rare tumors of neuroectodermal origin which occur in 0.1-0.2% of patients with hypertension. We sought to evaluate the presence and activity of BAT surrounding adrenal PHEO in a well-studied sample of 11 patients who were dia...

journal_title：International journal of endocrinology

authors： Iacobellis G,Di Gioia C,Petramala L,Chiappetta C,Serra V,Zinnamosca L,Marinelli C,Ciardi A,De Toma G,Letizia C

更新日期：2013-01-01 00:00:00

abstract：:A quarter of men with obesity or type 2 diabetes have hypogonadotropic hypogonadism. Animal studies and in vitro data have shown that insulin action and insulin responsiveness in the brain are necessary for the maintenance of the functional integrity of the hypothalamo-hypophyseal-gonadal axis. We conducted a randomiz...

journal_title：International journal of endocrinology

authors： Dhindsa S,Chemitiganti R,Ghanim H,Santiago E,Haider A,Chaar N,Mok M,McKee A,Dandona P

更新日期：2018-10-31 00:00:00

abstract：:Parathyroid glands contain the vitamin D receptor (VDR) and 25-hydroxyvitamin D-1α-hydroxylase (CYP27B1) and 24-hydroxylase (CYP24A1), which catalyze the production and degradation of 1,25-dihydroxyvitamin D [1,25(OH)2D], respectively. Previous studies have shown that the serum level of intact parathyroid hormone (iPT...

journal_title：International journal of endocrinology

authors： Jiang Y,Liao L,Li J,Wang L,Xie Z

更新日期：2020-04-09 00:00:00

abstract：:The increased prevalence of obesity represents, currently, one of the major public health issues, due to its consequences on physical and psychological health status as well as on the psychosocial functioning. As defined by the World Health Organization, sexual health is "a state of physical, emotional, mental, and so...

journal_title：International journal of endocrinology

authors： Poggiogalle E,Di Lazzaro L,Pinto A,Migliaccio S,Lenzi A,Donini LM

更新日期：2014-01-01 00:00:00

abstract：Background:Diagnosing polycystic ovary syndrome (PCOS) is based on ovulatory dysfunction, ovarian ultrasound data, and androgen excess. Total testosterone is frequently used to identify androgen excess, but testosterone is mainly bound to sex hormone-binding globulin (SHBG) and albumin. Only 1-2% of nonprotein-bound te...

journal_title：International journal of endocrinology

authors： Antonio L,Pauwels S,Laurent MR,Vanschoubroeck D,Jans I,Billen J,Claessens F,Decallonne B,De Neubourg D,Vermeersch P,Vanderschueren D

更新日期：2018-09-10 00:00:00

abstract：:The chemosensitivity of anaplastic thyroid cancer (ATC) to some cytotoxic agents was investigated by the histoculture drug response assay (HDRA). Thirty specimens from 22 patients with ATC were obtained from surgically resected subjects. The drugs tested were paclitaxel (PTX), docetaxel (DOC), adriamycin (ADM), nedapl...

journal_title：International journal of endocrinology

authors： Uruno T,Masaki C,Akaishi J,Matsuzu K,Suzuki A,Ohkuwa K,Shibuya H,Kitagawa W,Nagahama M,Sugino K,Ito K

更新日期：2015-01-01 00:00:00

abstract：:There is inconsistency among published guidelines for the optimal diagnostic and management pathways for patients with typical (TC) or atypical (AC) pulmonary carcinoid tumours. We conducted a UK-wide clinician survey to assess current practice for the diagnosis, management, and follow-up of patients with TC/AC and de...

journal_title：International journal of endocrinology

authors： Mansoor W,Ferguson S,Ross V,Talbot D

更新日期：2020-02-28 00:00:00

abstract：:Objectives. The roles of PI3K/AKT/mTOR and MAPK/ERK pathways involved in the pathogenesis of pheochromocytoma and paraganglioma (PPGL) were demonstrated mostly by in vitro studies with rat or mouse cells and were mainly studied at transcriptional level. This study aimed to investigate the effect of these pathways on t...

journal_title：International journal of endocrinology

authors： Du J,Tong A,Wang F,Cui Y,Li C,Zhang Y,Yan Z

更新日期：2016-01-01 00:00:00

abstract：:Anaplastic thyroid cancers (ATC) are among the most aggressive human neoplasms with a dire prognosis and a median survival time of few months from the diagnosis. The complete absence of effective therapies for ATC renders the identification of novel therapeutic approaches sorely needed. Chromosomal instability, a feat...

journal_title：International journal of endocrinology

authors： Baldini E,D'Armiento M,Ulisse S

更新日期：2014-01-01 00:00:00

abstract：Objective:Many patients with diabetes opt to fast for lab tests, especially for lipid profiles, thus missing breakfast. In parallel, recent studies and international guidelines have indicated that routine fasting for lipid panels may not be necessary. Missing breakfast while fasting for lab tests may invoke hypoglycemi...

journal_title：International journal of endocrinology

authors： Aldasouqi S,Mora S,Bhalla G,Kakumanu N,Corser W,Abela G,Dlewati M,Estrada K,Almounajed A,Tabbaa T,Hammoud J,Newkirk C

更新日期：2018-10-24 00:00:00