当前位置： SCI文献检索 > International Journal of Endocrinology期刊下所有文献 > Relationship between Subclinical Thyroid Dysfunction and the Risk of Cardiovascular Outcomes: A Systematic Review and Meta-Analysis of Prospective Cohort Studies.

Relationship between Subclinical Thyroid Dysfunction and the Risk of Cardiovascular Outcomes: A Systematic Review and Meta-Analysis of Prospective Cohort Studies.

Abstract：

BACKGROUND:Evidence on the association between subclinical thyroid dysfunction and the risk of cardiovascular outcomes are conflicting. METHODS AND RESULTS:PubMed, EMbase, Web of Science, Cochrane Library, and China Biology Medicine (CBM) databases were searched from inception to July 10, 2016. A total of 16 studies were included for meta-analysis. We found that subclinical hypothyroidism was not correlated with coronary heart disease (CHD) (RR = 1.17; 95% CI, 0.91-1.52), total mortality (RR = 1.02; 95% CI, 0.93-1.13), cardiovascular mortality (RR = 1.06; 95% CI, 0.77-1.45), heart failure (RR = 1.17; 95% CI, 0.87-1.57), and atrial fibrillation (RR = 1.05; 95% CI, 0.91-1.21), except CHD mortality (RR = 1.37; 95% CI, 1.03-1.84). Subgroup analysis indicated a higher estimation risk in CHD (RR = 1.54; 95% CI, 1.00-2.39), cardiovascular mortality (RR = 2.14; 95% CI, 1.43-3.22), and CHD mortality (RR = 1.54; 95% CI, 1.11-2.15) among participants < 65 years. Furthermore, subclinical hyperthyroidism was found to be associated with CHD (RR = 1.20; 95% CI, 1.02-1.42), total mortality (RR = 1.27; 95% CI, 1.07-1.51), and CHD mortality (RR = 1.45; 95% CI, 1.12-1.86). CONCLUSIONS:Subclinical hypothyroidism is likely associated with an increased risk of CHD mortality, and subclinical hyperthyroidism is likely associated with increased risk of CHD, CHD mortality, and total mortality.

journal_name

Int J Endocrinol

journal_title

International journal of endocrinology

authors

Sun J,Yao L,Fang Y,Yang R,Chen Y,Yang K,Tian L

doi

10.1155/2017/8130796

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

8130796

eissn

1687-8337

issn

1687-8345

journal_volume

2017

pub_type

杂志文章,评审

相关文献

International Journal of Endocrinology文献大全
  • Evidences of Polymorphism Associated with Circadian System and Risk of Pathologies: A Review of the Literature.

    abstract：:The circadian system is a supraphysiological system that modulates different biological functions such as metabolism, sleep-wake, cellular proliferation, and body temperature. Different chronodisruptors have been identified, such as shift work, feeding time, long days, and stress. The environmental changes and our mod...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章,评审

    doi：10.1155/2016/2746909

    authors： Valenzuela FJ,Vera J,Venegas C,Muñoz S,Oyarce S,Muñoz K,Lagunas C

    更新日期：2016-01-01 00:00:00

  • Perspectives on Peripheral Neuropathy as a Consequence of Metformin-Induced Vitamin B12 Deficiency in T2DM.

    abstract：:Peripheral neuropathy (PN) is a primary complication of type 2 diabetes mellitus (T2DM) and a direct manifestation of vitamin B12 deficiency. Examining the effects of metformin use on PN status became imperative following clinical studies that showed the vitamin B12-lowering effect of the medication. The complexity of...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章,评审

    doi：10.1155/2017/2452853

    authors： Ahmed MA,Muntingh GL,Rheeder P

    更新日期：2017-01-01 00:00:00

  • Iodine Supplementation: Usage "with a Grain of Salt".

    abstract：:Iodine supplementation through salt iodization is a worldwide, effective strategy for preventing iodine deficiency-related problems. Its safety and efficacy profile has been extensively investigated, and benefits far outweigh the potential iodine-induced risks. Moreover, iodine supplementation during pregnancy in orde...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章,评审

    doi：10.1155/2015/312305

    authors： Prete A,Paragliola RM,Corsello SM

    更新日期：2015-01-01 00:00:00

  • Rare Somatic MEN1 Gene Pathogenic Variant in a Patient Affected by Atypical Parathyroid Adenoma.

    abstract：Objective:Atypical parathyroid adenoma is a rare neoplasm, showing atypical histological features intermediate between classic benign adenoma and the rarest parathyroid carcinoma, whose the clinical behaviour and outcome is not yet understood or predictable. Up to date only two cases of atypical adenoma were found asso...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章

    doi：10.1155/2020/2080797

    authors： Cinque L,Pugliese F,Clemente C,Castellana S,Leone MP,de Martino D,Balsamo T,Battista C,Biagini T,Graziano P,Castori M,Scillitani A,Guarnieri V

    更新日期：2020-04-27 00:00:00

  • Strain US Elastography for the Characterization of Thyroid Nodules: Advantages and Limitation.

    abstract：:Thyroid nodules, with their high prevalence in the general population, represent a diagnostic challenge for clinicians. Ultrasound (US), although absolutely reliable in detecting thyroid nodules, is still not accurate enough to differentiate them into benign and malignant. A promising novel modality, US elastography, ...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章,评审

    doi：10.1155/2015/908575

    authors： Cantisani V,Grazhdani H,Drakonaki E,D'Andrea V,Di Segni M,Kaleshi E,Calliada F,Catalano C,Redler A,Brunese L,Drudi FM,Fumarola A,Carbotta G,Frattaroli F,Di Leo N,Ciccariello M,Caratozzolo M,D'Ambrosio F

    更新日期：2015-01-01 00:00:00

  • Growth retardation in children with kidney disease.

    abstract：:Growth failure is almost inextricably linked with chronic kidney disease (CKD) and end-stage renal disease (ESRD). Growth failure in CKD has been associated with both increased morbidity and mortality. Growth failure in the setting of kidney disease is multifactorial and is related to poor nutritional status as well a...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章,评审

    doi：10.1155/2013/970946

    authors： Salas P,Pinto V,Rodriguez J,Zambrano MJ,Mericq V

    更新日期：2013-01-01 00:00:00

  • Aerobic Training Associated with Arginine Supplementation Reduces Collagen-Induced Platelet Hyperaggregability in Rats under High Risk to Develop Metabolic Syndrome.

    abstract：Background:Increased platelet response is seen in individuals with metabolic syndrome. Previous reports have shown that arginine supplementation and aerobic exercise training enhance vascular nitric oxide (NO) activity and inhibit platelet hyperaggregability; however, the effects of their association remain unknown. A...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章

    doi：10.1155/2019/8919435

    authors： Motta NAV,Fumian MM,Medeiros RF,Lima GF,Scaramello CBV,Oliveira KJ,Nóbrega ACL,Brito FCF

    更新日期：2019-01-06 00:00:00

  • Differences in the Cardiometabolic Control in Type 2 Diabetes according to Gender and the Presence of Cardiovascular Disease: Results from the eControl Study.

    abstract：:The objective of this cross-sectional study was to assess differences in the control and treatment of modifiable cardiovascular risk factors (CVRF: HbA1c, blood pressure [BP], LDL-cholesterol, body mass index, and smoking habit) according to gender and the presence of cardiovascular disease (CVD) in patients with type...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章

    doi：10.1155/2014/131709

    authors： Franch-Nadal J,Mata-Cases M,Vinagre I,Patitucci F,Hermosilla E,Casellas A,Bolivar B,Mauricio D

    更新日期：2014-01-01 00:00:00

  • Synergistic Effect of Hyperglycemia and p27(kip1) Suppression on Adult Mouse Islet Beta Cell Replication.

    abstract：:The complementary role of hyperglycemia and p27(kip1) suppression on islet beta cell regeneration was investigated in a syngeneic mouse model. p27(kip1) gene silencing was performed by infecting islets of C57BL/6 with shRNA lentiviral particles. At 54 hours after viral infection, p27(kip1) protein content in cultured ...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章

    doi：10.1155/2012/417390

    authors： Chen ST,Fu SH,Hsu S,Huang YY,Hsu BR

    更新日期：2012-01-01 00:00:00

  • 11β-Hydroxysteroid Dehydrogenase 2 in Preeclampsia.

    abstract：:Preeclampsia is a serious medical problem affecting the mother and her child and influences their health not only during the pregnancy, but also many years after. Although preeclampsia is a subject of many research projects, the etiology of the condition remains unclear. One of the hypotheses related to the etiology o...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章,评审

    doi：10.1155/2016/5279462

    authors： Kosicka K,Siemiątkowska A,Główka FK

    更新日期：2016-01-01 00:00:00

  • Serum Osteoprotegerin Is a Potential Biomarker of Insulin Resistance in Chinese Postmenopausal Women with Prediabetes and Type 2 Diabetes.

    abstract：:The aim of this study is to investigate the circulating OPG levels in postmenopausal women with diabetes and prediabetes and explore the relationships between serum OPG and insulin resistance. A total of 271 unrelated Chinese postmenopausal women were recruited in this study. The subjects were divided into type 2 diab...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章

    doi：10.1155/2017/8724869

    authors： Duan P,Yang M,Wei M,Liu J,Tu P

    更新日期：2017-01-01 00:00:00

  • High fasting insulin levels and insulin resistance may be linked to idiopathic recurrent pregnancy loss: a case-control study.

    abstract：:Objective. Patients with more than two spontaneous pregnancy losses are diagnosed with recurrent pregnancy loss. The aim of this study was to evaluate the IR (insulin resistance) in patients with idiopathic recurrent pregnancy loss. Material and Method. A single center, case control study was performed on one hundred ...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章

    doi：10.1155/2013/576926

    authors： Ispasoiu CA,Chicea R,Stamatian FV,Ispasoiu F

    更新日期：2013-01-01 00:00:00

  • Pregnancy Ketonemia and Development of the Fetal Central Nervous System.

    abstract：:Glucose is the major source of energy for the human brain which in turn uses ketone bodies as a supplement for energy deficit in glucose cell deficiency conditions. Pregnancy complicated by gestational diabetes is a condition associated with significantly increased risk of ketonemia development. The data available pro...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章,评审

    doi：10.1155/2018/1242901

    authors： Bronisz A,Ozorowski M,Hagner-Derengowska M

    更新日期：2018-06-04 00:00:00

  • Therapeutic Outcomes of Patients with Multifocal Papillary Thyroid Microcarcinomas and Larger Tumors.

    abstract：:A retrospective review of 626 patients with multifocal papillary thyroid carcinoma (PTC) including 147 patients (23.5%) with multifocal papillary thyroid microcarcinoma (PTMC) from a total of 2,536 patients with PTC who visited the Chang Gung Medical Center in Linkou, Taiwan, was performed. A comparison of the clinica...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章

    doi：10.1155/2017/4208178

    authors： Ng SC,Kuo SF,Chen ST,Hsueh C,Huang BY,Lin JD

    更新日期：2017-01-01 00:00:00

  • Latent Inflammation and Insulin Resistance in Adipose Tissue.

    abstract：:Obesity is a growing problem in modern society and medicine. It closely associates with metabolic disorders such as type 2 diabetes mellitus (T2DM) and hepatic and cardiovascular diseases such as nonalcoholic fatty liver disease, atherosclerosis, myocarditis, and hypertension. Obesity is often associated with latent i...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章,评审

    doi：10.1155/2017/5076732

    authors： Stafeev IS,Vorotnikov AV,Ratner EI,Menshikov MY,Parfyonova YV

    更新日期：2017-01-01 00:00:00

  • Free Testosterone Reflects Metabolic as well as Ovarian Disturbances in Subfertile Oligomenorrheic Women.

    abstract：Background:Diagnosing polycystic ovary syndrome (PCOS) is based on ovulatory dysfunction, ovarian ultrasound data, and androgen excess. Total testosterone is frequently used to identify androgen excess, but testosterone is mainly bound to sex hormone-binding globulin (SHBG) and albumin. Only 1-2% of nonprotein-bound te...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章

    doi：10.1155/2018/7956951

    authors： Antonio L,Pauwels S,Laurent MR,Vanschoubroeck D,Jans I,Billen J,Claessens F,Decallonne B,De Neubourg D,Vermeersch P,Vanderschueren D

    更新日期：2018-09-10 00:00:00

  • Long-term results after treatment of very low-, low-, and high-risk thyroid cancers in a combined setting of thyroidectomy and radio ablation therapy in euthyroidism.

    abstract：:Introduction. Differentiated thyroid cancer treatment usually consists of thyroidectomy and radio ablation in hypothyroidism 4-6 weeks after surgery. Replacing hypothyroidism by recombinant human thyroid stimulating hormone can facilitate radio ablation in euthyroidism within one week after surgery. The outcome of thi...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章

    doi：10.1155/2013/769473

    authors： Emmanouilidis N,Schrem H,Winkler M,Klempnauer J,Scheumann GF

    更新日期：2013-01-01 00:00:00

  • Liraglutide Exerts Antidiabetic Effect via PTP1B and PI3K/Akt2 Signaling Pathway in Skeletal Muscle of KKAy Mice.

    abstract：:Background. Liraglutide (a glucagon-like peptide 1 analog) was used for the treatment of type 2 diabetes (T2DM) which could produce glucose-dependent insulin secretion. Aim. The aim was to investigate whether liraglutide could improve myofibril and mitochondria injury in skeletal muscle and the mechanisms in diabetic ...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章

    doi：10.1155/2014/312452

    authors： Ji W,Chen X,Lv J,Wang M,Ren S,Yuan B,Wang B,Chen L

    更新日期：2014-01-01 00:00:00

  • Prolactin and male fertility: the long and short feedback regulation.

    abstract：:In the last 20 years, a pituitary-hypothalamus tissue culture system with intact neural and portal connections has been developed in our lab and used to understand the feedback mechanisms that regulate the secretions of adenohypophyseal hormones and fertility of male rats. In the last decade, several in vivo rat model...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章

    doi：10.1155/2009/687259

    authors： Gill-Sharma MK

    更新日期：2009-01-01 00:00:00

  • Clinical Features, Treatment, and Surveillance of Hyperparathyroidism-Jaw Tumor Syndrome: An Up-to-Date and Review of the Literature.

    abstract：:Hyperparathyroidism-jaw tumor (HPT-JT) syndrome is an autosomal dominant disorder characterized by parathyroid tumors in association with fibro-osseous jaw tumors and uterine and renal lesions. HPT-JT syndrome is caused by germline mutations of the cell division cycle 73 (CDC73) gene that encodes the parafibromin, a 5...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章,评审

    doi：10.1155/2019/1761030

    authors： Torresan F,Iacobone M

    更新日期：2019-12-18 00:00:00

  • GNPDA2 Gene Affects Adipogenesis and Alters the Transcriptome Profile of Human Adipose-Derived Mesenchymal Stem Cells.

    abstract：Background:Genome-wide association studies have found an obesity-related single-nucleotide polymorphism rs10938397 near the glucosamine-6-phosphate deaminase 2 gene (GNPDA2) encoding, an enzyme that catalyzes the deamination of the glucosamine-6-phosphate involved in the hexosamine signaling pathway, but the molecular ...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章

    doi：10.1155/2019/9145452

    authors： Wu L,Ma F,Zhao X,Zhang MX,Wu J,Mi J

    更新日期：2019-08-01 00:00:00

  • The Association between the Epicardial Adipose Tissue Thickness and Oxidative Stress Parameters in Isolated Metabolic Syndrome Patients: A Multimarker Approach.

    abstract：:The risk for cardiovascular diseases and type 2 diabetes mellitus significantly increases in the patient population with metabolic syndrome (MeS). The present study aimed to investigate the association between the epicardial adipose tissue thickness (EATT) and the oxidative stress parameters in MeS patients. The study...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章

    doi：10.1155/2014/954045

    authors： Demir B,Demir E,Acıksarı G,Uygun T,Utku IK,Gedikbasi A,Caglar IM,Pirhan O,Tureli HO,Oflar E,Ungan İ,Ciftci S,Karakaya O

    更新日期：2014-01-01 00:00:00

  • TSH Variability of Patients Affected by Differentiated Thyroid Cancer Treated with Levothyroxine Liquid Solution or Tablet Form.

    abstract：BACKGROUND:Recent guidelines from the American Thyroid Association (ATA) indicate that, in many patients affected by differentiated thyroid cancer (DTC), the serum TSH should be maintained between 0.1 and 0.5 mU/L. The purpose of this study was to evaluate the TSH variability of patients affected by DTC treated with li...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章

    doi：10.1155/2017/7053959

    authors： Cappelli C,Pirola I,Gandossi E,Casella C,Lombardi D,Agosti B,Marini F,Delbarba A,Castellano M

    更新日期：2017-01-01 00:00:00

  • GnRH Antagonist Improves Pubertal Cyclophosphamide-Induced Long-Term Testicular Injury in Adult Rats.

    abstract：Background:Gonadal injury following chemotherapy is of increasing importance with the continuous improvement of survival rates. The protection of gonadotropin hormone antagonist (GnRHant) in long-term adult survivors of adolescent cancers and some autoimmune diseases has not yet been evaluated. Methods:The present stu...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章

    doi：10.1155/2018/4272575

    authors： Xie R,Chen L,Wu H,Chen T,Wang F,Chen X,Sun H,Li X

    更新日期：2018-06-10 00:00:00

  • Vitamin d status in central europe.

    abstract：:Little published information is available regarding epidemiological data on vitamin D status in the large geographical region of Central Europe (CE). We searched the journal literature with regard to 25(OH)D concentrations among community-dwelling or healthy people living in CE. 25(OH)D concentrations varied by age, s...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章,评审

    doi：10.1155/2014/589587

    authors： Pludowski P,Grant WB,Bhattoa HP,Bayer M,Povoroznyuk V,Rudenka E,Ramanau H,Varbiro S,Rudenka A,Karczmarewicz E,Lorenc R,Czech-Kowalska J,Konstantynowicz J

    更新日期：2014-01-01 00:00:00

  • The Age-Specific Association of Waist Circumference and Risk of Chronic Kidney Disease in Patients with Type 2 Diabetes Mellitus in Shandong, China.

    abstract：:Objective. To examine the association of three most common obesity measures including body mass index (BMI), waist circumference (WC), and waist-to-hip ratio (WHR) with chronic kidney disease (CKD) risk in patients with type 2 diabetes mellitus (T2D). Design. Cross-sectional evaluation of the effect of anthropometric ...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章

    doi：10.1155/2015/715871

    authors： Xu L,Yu W,Huang P,Li C,Li Y,Wang M,Xu Q,Wang J,Zheng C,Qu B,Zhao Y,Niu M,Wang O,Gong F

    更新日期：2015-01-01 00:00:00

  • Exercise for hepatic fat accumulation in type 2 diabetic subjects.

    abstract：:Type 2 diabetes is characterized by frequent ectopic fat accumulation in several tissues and organs. In particular, a number of studies showed that these subjects frequently have hepatic fat accumulation, which may play a role in the metabolic abnormalities typical of diabetes and has been also linked to increased ris...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章,评审

    doi：10.1155/2013/309191

    authors： Bacchi E,Moghetti P

    更新日期：2013-01-01 00:00:00

  • Low serum magnesium level is associated with microalbuminuria in chinese diabetic patients.

    abstract：:Whether serum magnesium deficiency is independently associated with the prevalence of microalbuminuria is still unclear. The objective of the present study was to elucidate the association between serum magnesium and microalbuminuria in diabetic patients. A cross-sectional study was conducted in 1829 diabetic subjects...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章

    doi：10.1155/2013/580685

    authors： Xu B,Sun J,Deng X,Huang X,Sun W,Xu Y,Xu M,Lu J,Bi Y

    更新日期：2013-01-01 00:00:00

  • Four-Point Preprandial Self-Monitoring of Blood Glucose for the Assessment of Glycemic Control and Variability in Patients with Type 2 Diabetes Treated with Insulin and Vildagliptin.

    abstract：:The study explored the utility of four-point preprandial glucose self-monitoring to calculate several indices of glycemic control and variability in a study adding the DPP-4 inhibitor vildagliptin to ongoing insulin therapy. This analysis utilized data from a double-blind, randomized, placebo-controlled crossover stud...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章

    doi：10.1155/2015/484231

    authors： Tura A,Farngren J,Schweizer A,Foley JE,Pacini G,Ahrén B

    更新日期：2015-01-01 00:00:00

  • The Prevalence and Associated Risk Factors of Impaired Glucose Regulation in Chinese Adults: A Population-Based Cross-Sectional Study.

    abstract：:The goal of this study was to determine the prevalence and associated risk factors of impaired glucose regulation (IGR) in the population of Tongzhou, China, and to provide scientific basis for preventive interventions. In the study, the overall age-standardized prevalence of IGR (16.0%) in Tongzhou residents was high...

    journal_title：International journal of endocrinology

    pub_type： 杂志文章

    doi：10.1155/2015/731583

    authors： Zhao D,Wu N,Yang J,Liu S,Zhang N,Wang X,Zhang H

    更新日期：2015-01-01 00:00:00