Abstract：
:Female rats were exposed to local γ-irradiation of the right hindpaw in doses of 30-50 Gy at 131-154 sGy/min dose rate. Radioprotector indralin was administered per os 15 min prior to irradiation, monizol was injected intraperitoneally 5 min after irradiation. Indralin showed marked radioprotective properties both for acute and delayed symptoms of local radiation injuries. In combination with monizol, radioprotective effect of indralin was potentiated to dose reduction factor of 1.4-1.5 both for radiation burn severity reduction and for restriction of postradiational contracture development and amputation of the irradiated limb.
journal_name
Bull Exp Biol Medjournal_title
Bulletin of experimental biology and medicineauthors
Vasin MV,Ushakov IB,Kovtun VY,Semenova LA,Komarova SN,Galkin AA,Afanas'ev RVdoi
10.1007/s10517-015-3065-8subject
Has Abstractpub_date
2015-10-01 00:00:00pages
747-9issue
6eissn
0007-4888issn
1573-8221pii
10.1007/s10517-015-3065-8journal_volume
159pub_type
杂志文章abstract：:Preparation containing ultralow doses of antibodies to stem cell factor considerably activates bone marrow myelopoiesis suppressed by cyclophosphamide. This effect of the preparation is based on stimulation of proliferation of committed hemopoietic precursors and increase in functional activity of adherent elements of...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-010-0764-z
更新日期：2009-09-01 00:00:00
abstract：:In experiments on Wistar rats we studied the effect of low-frequency electromagnetic field rotating in either right-handed or a left-handed sense on proteolytic activity of pepsin. The right-handed rotating field increased, while left-handed rotating field decreased pepsin activity. Possible mechanisms of these change...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
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abstract：:In vivo cytogenetic effects of cyclophosphamide was simultaneously evaluated in 7 mouse organs. Cyclophosphamide produced most pronounced changes in the urinary bladder and bone marrow, the main target organs for this carcinogen. Mutagenic effects of the preparation were also detected in the lungs, large intestine, an...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1023/a:1017916622451
更新日期：2001-04-01 00:00:00
abstract：:We compared the efficiency of different stereoisomers of organic magnesium salts (Mg DL-, Mg D-, and Mg L-aspartate and Mg L- and Mg DL-glutamate) after oral administration under conditions of furosemide-induced magnesium deficiency. The time to complete compensation of erythrocyte magnesium level was 5 days for Mg L-...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-011-1323-y
更新日期：2011-07-01 00:00:00
abstract：:We analyzed the expression of galectin-1 and galectin-3 in tumor tissue in stomach and colorectal cancer with and without tissue eosinophilia. Low expression of galectin-3 was detected in all patients with malignant gastrointestinal tumors irrespective of the presence of eosinophilia. Low expression of galectin-1 was ...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-018-4142-6
更新日期：2018-06-01 00:00:00
abstract：:We demonstrated specific changes in platelet structure in different types of tuberculous process, in particular, shift in the proportion between alpha-granules, dense granules, different disorders in the mitochondrial and lysosomal apparatus, etc. The role of platelets in immune process is studied. Redistribution of a...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
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abstract：:In patients with viral and bacterial infectious mononucleosis during the acute period of disease and clinical convalescence blood content of CD72(+)and CD16(+)lymphocytes increased compared to normal. The count of CD8(+)cells increased in viral mononucleosis during convalescence and these changes persist in delayed pe...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1023/a:1020612822959
更新日期：2002-07-01 00:00:00
abstract：:The effects of intranasal administration of oxytocin on the levels and metabolism of monoamines in symmetrical structures of the brain of white outbred mice kept under conditions of long-term social isolation were studied by HPLC. Disappearance of initial right-sided asymmetry in the content of dopamine metabolites in...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-017-3887-7
更新日期：2017-10-01 00:00:00
abstract：:We studied functional activity of neutrophilic granulocytes and monocytes isolated from the peripheral blood of women during the follicular and luteal phases of the menstrual cycle. It was shown that phagocytic activity of neutrophilic granulocytes increases, their intracellular oxygen-dependent bactericidal activity ...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-018-4318-0
更新日期：2018-12-01 00:00:00
abstract：:Intraleukocytic microbicidal activity of blood neutrophilic granulocytes in cows increased with increasing the term of pregnancy, decreased over the first 2 days after labor, and increased again in the follow-up period. Activity of microbicidal systems markedly decreased after labor, especially in the winter-spring pe...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
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更新日期：2003-09-01 00:00:00
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journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-013-2123-3
更新日期：2013-06-01 00:00:00
abstract：:Interleukin-1beta mRNA, interleukin-1beta receptor mRNA, and erythropoietin receptor mRNA are expressed in the brain of (CBAxC57Bl)F1 mice. Immunization with sheep erythrocytes stimulated the expression of these cytokines in the cerebral hemispheres. Injection of recombinant erythropoietin reduced expression of interl...
journal_title：Bulletin of experimental biology and medicine
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doi：10.1023/a:1015112729103
更新日期：2002-01-01 00:00:00
abstract：:We studied processes of proliferation and differentiation of hemopoietic precursor cells in mice treated with granulocyte CSF under conditions of cytostatic myelodepression. It was found that the hemostimulating effect of original granulocyte CSF preparation consists in accelerated maturation of hemopoietic precursors...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-005-0235-0
更新日期：2005-01-01 00:00:00
abstract：:Drug resistance and viability of Mycobacterium tuberculosis were studied in 637 patients with pulmonary tuberculosis, detected by screening fluorography (group 1) and in 909 patients in whom the specific process was detected when they applied for medical care (group 2). The mycobacteria in the two groups did not diffe...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
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更新日期：2014-11-01 00:00:00
abstract：:We studied morphological changes in the myocardium during experimental myocardial infarction in rats with different resistance to hypoxia. Microscopic examination showed that morphological changes in the ischemic zone and adjacent tissues are different in rats with high and low resistance to acute ischemia. In highly ...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1023/a:1013600302382
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journal_title：Bulletin of experimental biology and medicine
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doi：10.1007/s10517-017-3857-0
更新日期：2017-09-01 00:00:00
abstract：:The effect of changed photoperiod (constant darkness) on the proliferation of Ehrlich ascitic tumor cells was demonstrated. Some mechanisms maintaining the proliferative homeostasis in Ehrlich ascitic tumor under conditions of constant darkness were studied, explaining more leveled pattern of circadian rhythms of cell...
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doi：10.1007/s10517-005-0356-5
更新日期：2005-05-01 00:00:00
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journal_title：Bulletin of experimental biology and medicine
pub_type： 临床试验,杂志文章
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更新日期：2005-07-01 00:00:00
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journal_title：Bulletin of experimental biology and medicine
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doi：10.1007/s10517-015-2948-z
更新日期：2015-07-01 00:00:00
abstract：:Comparative analysis of the state of the thymus, activity of cell component of the immune system, and open field behavior of Wistar and OXYS rats showed early involution of the thymus in OXYS rats. By morphological picture this involution corresponded to accidental involution and was paralleled by low level of delayed...
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更新日期：2003-12-01 00:00:00
abstract：:Study of the early embryogenesis process based on the previously suggested scheme of epithelial cambial cell work has shown that cambial (or stem) cells originate from the primary ectoderm and intensely express RhoA protein and slightly express Src kinase. This explains their stem properties and the absence of differe...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
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更新日期：2012-05-01 00:00:00
abstract：:Cytoplasmic Na/K imbalance induced by cytotoxic substances (ethylene glycol and cytochalasin B) was studied. Incubation in Dulbecco's medium with these cytotoxins caused changes in K and Na concentrations in the mouse two-cell embryo blastomer. The effects of both substances resulted in a drop of Na content in the emb...
journal_title：Bulletin of experimental biology and medicine
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journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
doi：10.1007/s10517-009-0522-2
更新日期：2009-04-01 00:00:00
abstract：:Local inflammatory response in the lungs and fi brogenic potential of multi-walled carbon nanotubes were studied in an acute aspiration experiment in mice. The doses were chosen based on the concentration of nanotubes in the air at a workplace of the company-producer. ELISA, fl ow cytometry, enhanced darkfield microsc...
journal_title：Bulletin of experimental biology and medicine
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abstract：:We studied the structure of rhythms of BP, HR (by telemetric monitoring), electrolyte excretion (by capillary electrophoresis), and products of epiphyseal melatonin (by the urinary concentration of 6-sulfatoxymelatonin measured by ELISA) in normotensive Wistar-Kyoto rats and spontaneously hypertensive SHR rats maintai...
journal_title：Bulletin of experimental biology and medicine
pub_type： 杂志文章
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更新日期：2019-11-01 00:00:00
abstract：:The rates of oxyhemoglobin drop and CO(2) release in dogs with magnetized and nonmagnetized blood were compared. Stationary magnetic field enhances blood oxygen capacity by no less than 24%. A hypothesis was proposed on formation of bioxyhemoglobin molecules under the effect of magnetic field, in which hem binds two O...
journal_title：Bulletin of experimental biology and medicine
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doi：10.1023/a:1017523407969
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