Regulation of proteolytic activity of pepsin in rats [correction of mice] by rotating electromagnetic field.

abstract：:The involvement of PI3K, ERK and p38-dependent signaling system in the regulation of functional activity of erythroid precursors after blood loss (30% of circulating volume) was studied. We demonstrated the important role of PI3K and p38 in the suppression of differentiation of erythroid precursors the contribution of...

journal_title：Bulletin of experimental biology and medicine

authors： Dygai AM,Zhdanov VV,Miroshnichenko LA,Udut EV,Zyuz'kov GN,Simanina EV,Sherstoboev EY,Chaikovskii AV,Stavrova LA,Burmina YV,Khrichkova TY,Reichart DV,Goldberg VE

更新日期：2015-02-01 00:00:00

abstract：:We studied expression of Flt-1 and Flk-1 receptors on tumor cells obtained from 83 patients with locally advanced breast cancer after neoadjuvant chemotherapy. The mean period of observations was 32.3 months. The median recurrence-free survival periods for Flt-1(+) and Flt-1(-) patients were 55 and 32 months, respecti...

journal_title：Bulletin of experimental biology and medicine

authors： Zhukova LG,Zhukov NV,Lichinitser MR

更新日期：2003-05-01 00:00:00

abstract：:A combination of electrochemical lysis and photodynamic therapy were used to attain complete resorption of M-1 sarcoma in rats; both treatment modalities were used with minimum parameters. Fotolon served as the photosensitizer for photodynamic therapy. Accumulation of the sensitizer in the tumor and normal tissue was ...

journal_title：Bulletin of experimental biology and medicine

authors： Mikhailovskaya AA,Kaplan MA,Brodskij RA,Bandurko LN

更新日期：2009-01-01 00:00:00

abstract：:Alloxan-induced diabetes mellitus in rats was characterized by persistent increase in blood levels of corticosterone, while chronic granulomatous inflammation induced by silicon dioxide and its combination with alloxan-induced diabetes mellitus were associated with transient increase in blood corticosterone level foll...

journal_title：Bulletin of experimental biology and medicine

authors： Kuznetsova NV,Palchikova NA,Selyatitskaya VG,Shkurupiy VA

更新日期：2010-11-01 00:00:00

abstract：:Clinical and laboratory studies were carried out in 38 pregnant women with antiphospholipid syndrome. Increased functional activity of platelets and decreased protein-producing function of the placenta were observed starting from the early terms of gestation. These disorders were followed by the development of hyperco...

journal_title：Bulletin of experimental biology and medicine

authors： Bogdanovich RN,Chikalovets IV

更新日期：2002-10-01 00:00:00

abstract：:Pronounced changes in the capillaries, hemodynamic disorders, epitheliocyte degeneration and atrophy develop in the buccal mucosa of patients with types I and II diabetes mellitus in the absence of inflammatory cellular infiltration or with facultative infiltration. The morphogenesis of pathological changes can be reg...

journal_title：Bulletin of experimental biology and medicine

authors： Balakhonov LV,Nepomnyashchikh LM,Aidagulova SV,Bakarev MA,Vlasova LF

更新日期：2006-11-01 00:00:00

abstract：:The efficiency of drug therapy should be evaluated by not only its directed action on specific organ or target parameter, but also its effects on general regulatory and adaptive status. ...

journal_title：Bulletin of experimental biology and medicine

authors： Pokrovskii VM,Kompaniets OG

更新日期：2008-06-01 00:00:00

abstract：:We studied the effect of adrenal cortex hormone dehydroepiandrosterone sulfate on maturation and functional activity of interferon-alpha-induced dendritic cells. Dehydroepiandrosterone sulfate stimulated differentiation and maturation of interferon-alpha-induced dendritic cell, which manifested in a decrease in the nu...

journal_title：Bulletin of experimental biology and medicine

authors： Leplina OY,Tikhonova MA,Sakchno LV,Tyrinova TV,Ostanin AA,Chernykh ER

更新日期：2009-07-01 00:00:00

abstract：:Intranigral administration of glutamate to rats with parkinsonian syndrome induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine augmented the development of parkinsonian symptoms (oligokinesia and muscular rigidity), but did not affect motor activity of intact animals. Memantine administered intraperitoneally in pa...

journal_title：Bulletin of experimental biology and medicine

authors： Kucheryanu VG,Kryzhanovskii GN

更新日期：2000-07-01 00:00:00

abstract：:We studied the effect of continuous vibration and treatment with licorice root (Glycyrrhiza glabra L.) on peripheral blood red cells in rabbits. Active substances of licorice root accelerated metabolism in cells of the bone marrow erythroid stem, enhanced compensatory reserve of the organism, and increased animal's re...

journal_title：Bulletin of experimental biology and medicine

authors： Adamyan TI,Gevorkyan ES,Minasyan SM,Oganesyan KR,Kirakosyan KA

更新日期：2005-08-01 00:00:00

abstract：:Data are presented on chemical study of flavonoid glycosides in some botanical subjects using matrix-assisted laser desorption ionization, compared to HPLC. The method of matrix-assisted laser desorption ionization (MALDI) allows characterizing the composition of anthocyanin and flavonoid mixture without preliminary s...

journal_title：Bulletin of experimental biology and medicine

authors： Novikov OO,Pisarev DI,Zhilyakova ET,Novikova MY,Pisareva NA,Voronkova OS,Bezmenova MD

更新日期：2013-01-01 00:00:00

abstract：:We studied the effects of stress exposure during the adolescent period of development (SAPD) on the parameters of inflammatory painful response and the level of depression-like behavior in prenatally stressed adult male rats. In addition, we analyzed the effects of selective serotonin (5-HT) reuptake inhibitor fluoxet...

journal_title：Bulletin of experimental biology and medicine

authors： Butkevich IP,Mikhailenko VA

更新日期：2020-07-01 00:00:00

abstract：:A cascade of pathological changes in the intact hemisphere developed in rats 6 months after focal unilateral traumatic brain injury: neuronal degeneration, hyperexpression of α-synuclein, APP (β-amyloid peptide precursor) protein, and glutamine synthetase in cells other than astrocytes. The development of these change...

journal_title：Bulletin of experimental biology and medicine

authors： Genrikhs EE,Voronkov DN,Kapkaeva MR,Isaev NK,Stelmashook EV

更新日期：2017-12-01 00:00:00

abstract：:Testosterone and its high-molecular-weight form (testosterone covalently immobilized on bovine serum albumin) induced a rise of intracellular calcium concentration. The effectiveness of dihydrotestosterone was much lower compared to that of testosterone. Gestagens drospirenone and, to a lesser extent, 17alpha-acetoxy-...

journal_title：Bulletin of experimental biology and medicine

authors： Popova NY,Dukhanin AS,Shimanovskii NL

更新日期：2007-05-01 00:00:00

abstract：:The peculiarities of the histological structure and morphometrical parameters of the dentition in ISIAH rats (inherited stress-induced arterial hypertension) before stress and after modeling of everyday life stress regimen (chronic stress) were compared with those in WAG rats. The area of blood vessels of the periodon...

journal_title：Bulletin of experimental biology and medicine

authors： Kolesnikova LR,Darenskaya MA,Kolesnikova LI,Grebenkina LA,Korytov LI,Batoroev YK,Belinskaya EI,Mikhalevich IM,Kolesnikov SI

更新日期：2019-05-01 00:00:00

abstract：:The effects of a new thietanylbenzimidazole derivative (K-134) on estrous cycles, conception processes, and sexual behavior of female rats were studied. Two-week oral treatment with K-134 in doses of 5 and 50 mg/kg shortened the estrus phase and prolonged proestrus. Changes in sexual behavior were presented by activat...

journal_title：Bulletin of experimental biology and medicine

authors： Kuzubova EA,Bugaeva LI,Sergeeva SA,Petrov VI,Kataev VA,Kharlamov IV,Mal'tsev MV

更新日期：2015-09-01 00:00:00

abstract：:We studied the effects of phenazepam (0.075 mg/kg) after pretreatment (5 minutes before) with naloxone (10 mg/kg) on open-field behavior of C57Bl/6 and BALB/c mice. In ex vivo experiments, we studied the effects of naloxone (1 and 10 mg/kg) on receptor binding of [(3)H]-flunitrazepam by membranes of brain fraction (P1...

journal_title：Bulletin of experimental biology and medicine

authors： Seredenin SB,Nadorova AV,Kolik LG,Yarkova MA

更新日期：2013-07-01 00:00:00

abstract：:Behavioral responses of 90-day-old male offspring from female Wistar rats exposed to restraint stress during the last week of pregnancy were studied in the formalin test. Specific biphasic behavioral response characterized acute (phase 1) and persistent tonic pain (phase 2). The intensity of nociceptive responses (eva...

journal_title：Bulletin of experimental biology and medicine

authors： Butkevich IP

更新日期：2002-02-01 00:00:00

abstract：:Isolated rat hearts were subjected to 30-min coronary artery occlusion followed by 120-min reperfusion. The hearts (n=8-12) were perfused with Krebs-Henseleit solution enriched with L-carnitine (0.5, 2.5 and 5 mM) for 10 min before and after ischemia or reperfusion and for the whole period of ischemia and reperfusion....

journal_title：Bulletin of experimental biology and medicine

authors： Najafi M,Garjani A,Maleki N,Eteraf Oskouei T

更新日期：2008-08-01 00:00:00

abstract：:The interaction between dopamine D1 and D2 receptors plays a role in immunomodulation. The results of thus interaction depends on the degree of receptor activation with selective agonists in different doses. Combined treatment with agonists of D1 and D2 receptors in high doses had a synergistic effect in the mechanism...

journal_title：Bulletin of experimental biology and medicine

authors： Devoino LV,Al'perina EL,Gevorgyan MM,Cheido MA

更新日期：2006-05-01 00:00:00

abstract：:Arginine-vasopressin or arginine-vasotocin hormones introduced into the small intestine are absorbed and exert a hydrosmotic effect. The amount of absorbed antidiuretic hormone increased when it is introduced with intestinal peptidase inhibitor aprotinin. These data attest to the possibility of absorption of pituitary...

journal_title：Bulletin of experimental biology and medicine

authors： Natochin YV,Shakhmatova EI

更新日期：2004-01-01 00:00:00

abstract：:Afala (ultralow-dose antibodies to prostate-specific antigen) injected for 60 days to rats with hormone-induced prostatitis caused by sulpiride prevented the development of prostatic hyperplasia and reduced the severity of histological changes. The effect of Afala was superior to that of the reference drug (Serenoa re...

journal_title：Bulletin of experimental biology and medicine

authors： Savelieva KV,Borovskaya TG,Kheyfets IA,Dugina JL,Sergeeva SA,Epstein OI

更新日期：2007-11-01 00:00:00

abstract：:In acute experiments on cats neural inotropic and lusitropic reactions of the heart to enhancement of pre- and afterload were assessed by changes in contractility and relaxation indices, which were preliminary chosen for their maximum specificity and sensitivity. The control cardiac responses to increased pre- and aft...

journal_title：Bulletin of experimental biology and medicine

authors： Alipov NN,Sokolov AV,Trubetskaya LV,Kuznetsova TE

更新日期：2003-04-01 00:00:00

abstract：:Animals were immunized with transmissible gastroenteritis virus conjugated with gold nanoparticles. The resultant antibodies had a higher titer than antibodies produced in response to native virus. Immunization with the antigen-colloidal gold complex led to a significant increase of the peritoneal macrophages respirat...

journal_title：Bulletin of experimental biology and medicine

authors： Staroverov SA,Vidyasheva IV,Gabalov KP,Vasilenko OA,Laskavyi VN,Dykman LA

更新日期：2011-08-01 00:00:00

abstract：:Cytogenetic analysis of karyotypes of hESM01-hESM04 human embryonic stem cells and substrains derived from these strains showed that all these strains retained normal karyotype during long-term culturing. Two substrains of embryonic stem cells with chromosome aberrations indicating clonal origin of these strains were ...

journal_title：Bulletin of experimental biology and medicine

authors： Prokhorovich MA,Lagar'kova MA,Shilov AG,Karamysheva TV,Kiselyov SL,Rubtsov NB

更新日期：2007-07-01 00:00:00

abstract：:We studied the effects and mechanisms of action of NaHS, an H2S donor, on isolated phenylephrine-precontracted bovine mesenteric lymph nodes. NaHS induced concentration-dependent relaxation of lymph nodes. Removal of the endothelium reduced, but did not abolish the relaxing effect of NaHS. The relaxing effect was redu...

journal_title：Bulletin of experimental biology and medicine

authors： Lobov GI

更新日期：2020-06-01 00:00:00

abstract：:We performed immunohistochemical analysis of the expression of TGFβ, galectin-1, vimentin, and thrombospondin in the mucosa in gastric cancer of diffuse and intestinal type associated with systemic undifferentiated connective tissue dysplasia. In diffuse gastric cancer, both with and without association with connectiv...

journal_title：Bulletin of experimental biology and medicine

authors： Naumova LA,Osipova ON,Klinnikova MG

更新日期：2019-04-01 00:00:00

abstract：:The effect of non-benzodiazepine anxiolytics on the ethanol-induced hyperlocomotion and behavioral sensitization was assessed in male DBA/2 mice. Selank that enhances activity of the endogenous opioid system (0.3 mg/kg, intraperitoneally), similar to the nonselective opiate receptor blocker naloxone (1.0 mg/kg, intrap...

journal_title：Bulletin of experimental biology and medicine

authors： Kolik LG,Nadorova AV,Seredenin SB

更新日期：2016-11-01 00:00:00

abstract：:We studied ultrastructure of nuclear compartment in cardiomyocytes during regenerative and plastic insufficiency of the myocardium induced by anthracycline antibiotic daunomycin. A peculiarity of ultrastructural organization of cardiomyocyte nuclei under these conditions is almost complete disappearance of the heteroc...

journal_title：Bulletin of experimental biology and medicine

authors： Nepomnyashchikh LM,Lushnikova EL,Semenov DE

更新日期：2000-12-01 00:00:00

abstract：:Typical signs of cardiomyoblasts were determined: high mitochondrial membrane potential and high number of mitochondria in these cells compared to fibroblasts. These signs can be used for identification of these cells. Energy-dependent accumulation of highly specific mitochondrial fluorescent probes applied for visual...

journal_title：Bulletin of experimental biology and medicine

authors： Khryapenkova TG,Plotnikov EY,Korotetskaya MV,Sukhikh GT,Zorov DB

更新日期：2008-10-01 00:00:00