Skin permeability of various non-steroidal anti-inflammatory drugs in man.

Abstract:

:The skin permeabilities of a series of eight salicylates and ten non-steroidal anti-inflammatory drugs were investigated in human subjects. The logarithms of % absorption through intact skin and of n-octanol/water partition coefficients (log P) of the test compounds were plotted against one another, and a parabolic relationship was obtained in both compound series.

journal_name

Life Sci

journal_title

Life sciences

authors

Yano T,Nakagawa A,Tsuji M,Noda K

doi

10.1016/0024-3205(86)90195-5

subject

Has Abstract

pub_date

1986-09-22 00:00:00

pages

1043-50

issue

12

eissn

0024-3205

issn

1879-0631

pii

0024-3205(86)90195-5

journal_volume

39

pub_type

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