Melanocytoma: nomenclature, pathogenesis, natural history and treatment.

Abstract:

:A melanocytoma (magnocellular nevus) is a benign pigmented tumor that may arise wherever uveal melanocytes are present. The most commonly observed site is on or adjacent to the optic nerve head. In the past this tumor was frequently misdiagnosed as a malignant melanoma and many unnecessary enucleations were carried out. Its clinical features are now well recognized and, fortunately, specimens of melanocytomas are rarely received in ocular pathology laboratories today. A review of the literature concerning this tumor is presented, with special reference to the changing concepts in nomenclature, pathogenesis, natural history, and treatment that have evolved in the past one hundred years. We also define the clinical and histopathological features of this tumor.

journal_name

Surv Ophthalmol

journal_title

Survey of ophthalmology

authors

Reidy JJ,Apple DJ,Steinmetz RL,Craythorn JM,Loftfield K,Gieser SC,Brady SE

doi

10.1016/0039-6257(85)90107-9

subject

Has Abstract

pub_date

1985-03-01 00:00:00

pages

319-27

issue

5

eissn

0039-6257

issn

1879-3304

pii

0039-6257(85)90107-9

journal_volume

29

pub_type

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