Corneal lymphangiogenesis in herpetic stromal keratitis.

Abstract:

:Corneal lymphangiogenesis is the extension of lymphatic vessels into the normally alymphatic cornea, a process that compromises the cornea's immune-privileged state and facilitates herpetic stromal keratitis (HSK). HSK results most commonly from infection by herpes simplex virus-1 (HSV-1) and is characterized by immune- and inflammation-mediated damage to the deep layers of the cornea. Current research demonstrates the potential of anti-lymphangiogenic therapy to decrease and prevent herpes-induced lymphangiogenesis.

journal_name

Surv Ophthalmol

journal_title

Survey of ophthalmology

authors

Park PJ,Chang M,Garg N,Zhu J,Chang JH,Shukla D

doi

10.1016/j.survophthal.2014.06.001

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

60-71

issue

1

eissn

0039-6257

issn

1879-3304

pii

S0039-6257(14)00126-X

journal_volume

60

pub_type

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