Abstract:
:In the present study the relationship between intraocular pressure (IOP) and pulsatile ocular blood flow (POBF) in low tension glaucoma (LTG) has been investigated. The POBF was measured using the Ocular Blood Flow system of Langham in undisturbed eyes and repeated at IOP increments of about 5 and 10 mmHg in 20 patients affected with bilateral LTG and in 25 healthy subjects matched for age, IOP, refractive error, arterial blood pressure and heart rate. The POBFs were 740.1 (SD 58.83) and 667 (SD 108) microliters/minute (microliter/min) in the control and LTG groups, respectively and statistically significantly different. The POBFs at an IOP increased by 5 mmHg were 658.1 (SD 60.2) and 457.3 (SD 74.8) microliter/min in the control and LTG groups, respectively; in the control group the mean POBF at an IOP increment of 10 mmHg was 552.1 microliters/min (SD 66.9), and in the LTG group was 317.7 microliters/min (SD 85.2). Statistical analysis of the data showed a significant difference of POBFs in the two groups either at an IOP increment of 5 or 10 mmHg (p < 0.0001). The substantial decrease of POBF with increased IOP in LTG eyes compared with normals shows an altered response of the vascular system in LTG. These findings are probably consistent with a lack of the myogenic autoregulation in reply to IOP-induced modifications of the perfusion pressure.
journal_name
Surv Ophthalmoljournal_title
Survey of ophthalmologyauthors
Quaranta L,Manni G,Donato F,Bucci MGdoi
10.1016/0039-6257(94)90064-7subject
Has Abstractpub_date
1994-05-01 00:00:00pages
S177-81; discussion S182eissn
0039-6257issn
1879-3304pii
0039-6257(94)90064-7journal_volume
38 Supplpub_type
临床试验,杂志文章abstract::In addition to the original and highly popular instrument designed by Goldmann, three other projection perimeters are now available. Features of the Goldmann, Topcon, Marco and Rodenstock machines are examined and compared. ...
journal_title:Survey of ophthalmology
pub_type: 杂志文章
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abstract::Phosphorus (31P) nuclear magnetic resonance (NMR) represents a noninvasive technique for the assessment of ocular metabolism. The measurement of a spectrum of phosphorus-containing metabolites (e.g., phosphorylated sugars and ATP), including a number of heretofore uncharacterized metabolites, can be made with a single...
journal_title:Survey of ophthalmology
pub_type: 杂志文章
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journal_title:Survey of ophthalmology
pub_type: 杂志文章
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journal_title:Survey of ophthalmology
pub_type: 杂志文章,评审
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更新日期:2008-05-01 00:00:00
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journal_title:Survey of ophthalmology
pub_type: 杂志文章,评审
doi:10.1016/j.survophthal.2018.11.002
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journal_title:Survey of ophthalmology
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journal_title:Survey of ophthalmology
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journal_title:Survey of ophthalmology
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journal_title:Survey of ophthalmology
pub_type: 杂志文章,评审
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journal_title:Survey of ophthalmology
pub_type: 杂志文章
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更新日期:1987-09-01 00:00:00
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journal_title:Survey of ophthalmology
pub_type: 杂志文章,评审
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journal_title:Survey of ophthalmology
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journal_title:Survey of ophthalmology
pub_type: 杂志文章,评审
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journal_title:Survey of ophthalmology
pub_type: 杂志文章,评审
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journal_title:Survey of ophthalmology
pub_type: 杂志文章,评审
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journal_title:Survey of ophthalmology
pub_type: 杂志文章
doi:10.1016/0039-6257(94)90176-7
更新日期:1994-03-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:Survey of ophthalmology
pub_type: 杂志文章
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pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Survey of ophthalmology
pub_type: 杂志文章,评审
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更新日期:2013-09-01 00:00:00
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