Wegener's granulomatosis presenting with sclerokeratitis diagnosed by antineutrophil cytoplasmic autoantibodies (ANCA).

Abstract:

:A 23-year-old male presented with bilateral sclerokeratitis. He reported recent bronchitis, sinusitis, dyspnea on exertion, hemoptysis, arthralgias and myalgias. Wegener's granulomatosis was diagnosed by a positive antineutrophil cytoplasmic autoantibody (ANCA) test and a nasal and subglotic biopsy showing granulomatous inflammation. Treatment with cyclophosphamide, systemic corticosteroids and trimethoprim/sulfamethoxazole resulted in resolution of the sclerokeratitis and remission of the disease.

journal_name

Surv Ophthalmol

journal_title

Survey of ophthalmology

authors

Florine CW,Dwyer M,Holland EJ

doi

10.1016/0039-6257(93)90067-h

subject

Has Abstract

pub_date

1993-03-01 00:00:00

pages

373-6

issue

5

eissn

0039-6257

issn

1879-3304

pii

0039-6257(93)90067-H

journal_volume

37

pub_type

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