Systemic drug interactions with topical glaucoma medications.

abstract：OBJECTIVE:Laser photocoagulation treatment of the posterior pole of the retina is often complicated by immediate visual impairment, which is caused by the unavoidable laser-induced destruction of the normal tissue adjacent to the lesion. A neuroprotective therapy aimed at salvaging this normal tissue might enhance the ...

journal_title：Survey of ophthalmology

authors： Solberg Y,Dubinski G,Tchirkov M,Belkin M,Rosner M

更新日期：1999-10-01 00:00:00

abstract：:Ocular tissues, like those of other organs, exhibit limited morphologic reactions to trauma, i.e., hyperemia, abrupt vasodilation, increased blood flow; increased permeability of blood vessels, edema and increased tissue pressure (disrupted blood-ocular barrier); and later, a cellular inflammatory response. The cystoi...

journal_title：Survey of ophthalmology

authors： Sears ML

更新日期：1984-05-01 00:00:00

abstract：:Large population-based health administrative databases, clinical registries, and data linkage systems are a rapidly expanding resource for health research. Ophthalmic research has benefited from the use of these databases in expanding the breadth of knowledge in areas such as disease surveillance, disease etiology, he...

journal_title：Survey of ophthalmology

authors： Clark A,Ng JQ,Morlet N,Semmens JB

更新日期：2016-07-01 00:00:00

abstract：:Glutamatergic excitotoxicity has been implicated as a mechanism for injury in a variety of central nervous system pathologies, including glaucoma. Memantine, an NMDA-type glutamatergic open-channel blocker, has pharmacologic properties that make its efficacy greater under excitotoxic conditions, but lesser under norma...

journal_title：Survey of ophthalmology

authors： Hare W,WoldeMussie E,Lai R,Ton H,Ruiz G,Feldmann B,Wijono M,Chun T,Wheeler L

更新日期：2001-05-01 00:00:00

abstract：:The presence of retinal vasculopathy in the absence of typical predisposing factors should suggest a possible underlying hematologic abnormality. In such cases, a systemic investigation may reveal a potentially fatal hypercoagulability or hyperviscosity syndrome. Retinal vein occlusion is the most commonly encountered...

journal_title：Survey of ophthalmology

authors： Rajagopal R,Apte RS

更新日期：2016-03-01 00:00:00

abstract：:Autosomal dominant optic atrophy is an inherited optic neuropathy manifesting with variable penetrance and expressivity. Other genetic and environmental factors are postulated to contribute to more marked visual loss in some affected individuals. Optic neuropathy is also a known adverse effect of ethambutol therapy fo...

journal_title：Survey of ophthalmology

authors： Pradhan M,Sharp D,Best S,Vincent A,Vaphiades M

更新日期：2010-07-01 00:00:00

abstract：:The endothelium influences local vascular tone by releasing endothelium-derived relaxing factors such as nitric oxide, prostacyclin and a putative hyperpolarizing factor. In isolated ophthalmic arteries and the perfused eye, all endothelial factors importantly contribute to vascular regulation. In larger ophthalmic ve...

journal_title：Survey of ophthalmology

authors： Haefliger IO,Meyer P,Flammer J,Lüscher TF

更新日期：1994-09-01 00:00:00

abstract：:A 24-year-old man experienced the sudden onset of a painless superior-temporal visual field defect of the left eye. Fundoscopy showed peripapillary pigmentary changes and a few nasal retinal white spots. Automated perimetry demonstrated an enlarged blind spot. The differential diagnosis of the various presumed inflamm...

journal_title：Survey of ophthalmology

authors： Bhatti MT,Holt JL,Slavin M

更新日期：2005-03-01 00:00:00

abstract：:Drugs across many pharmacologic classes induce corneal epithelial changes. Many of these drugs have cationic amphiphilic structures, with a hydrophobic ring and hydrophilic cationic amine side chain that allow them to cross cell membranes. These drugs lead to intracellular phospholipid accumulation, often manifested i...

journal_title：Survey of ophthalmology

authors： Raizman MB,Hamrah P,Holland EJ,Kim T,Mah FS,Rapuano CJ,Ulrich RG

更新日期：2017-01-01 00:00:00

abstract：:Cystic macular lesions frequently contribute to impaired visual acuity in hereditary retinal dystrophies. Their pathogenesis varies and is not entirely understood. Carbonic anhydrase inhibitors have proven to be potentially efficacious, although not in all cases. We discuss the various factors and mechanisms implicate...

journal_title：Survey of ophthalmology

authors： Salvatore S,Fishman GA,Genead MA

更新日期：2013-11-01 00:00:00

abstract：:A melanocytoma (magnocellular nevus) is a benign pigmented tumor that may arise wherever uveal melanocytes are present. The most commonly observed site is on or adjacent to the optic nerve head. In the past this tumor was frequently misdiagnosed as a malignant melanoma and many unnecessary enucleations were carried ou...

journal_title：Survey of ophthalmology

authors： Reidy JJ,Apple DJ,Steinmetz RL,Craythorn JM,Loftfield K,Gieser SC,Brady SE

更新日期：1985-03-01 00:00:00

abstract：:This article describes the history and substance of New York State's proposal for a mandatory recredentialing program for physicians, its implications for the medical profession, and the pros and cons of instituting a recertification policy for ophthalmology. ...

journal_title：Survey of ophthalmology

authors： Grenell B,Studin I

更新日期：1990-07-01 00:00:00

abstract：:A 55-year-old woman presented with an eight-year history of progressive gait dysfunction and a 2-3 week history of horizontal diplopia. Examination of the patient revealed acute papilledema, intermittent esotropia, and upper and lower motor neuron findings in her lower extremities. CT scan of the head showed communica...

journal_title：Survey of ophthalmology

authors： Breen LA

更新日期：1994-03-01 00:00:00

abstract：:A 32-year-old woman experienced dizziness and headache for 5 months. She also complained of painless, progressive bilateral visual loss for several weeks. Before developing the initial symptoms, she had an uncomplicated pregnancy except for dizziness and systemic hypotension during the first term. Fundus examination d...

journal_title：Survey of ophthalmology

authors： Subirà O,Muñoz S,Sánchez JJ,Puyalto P,Lee AG

更新日期：2018-01-01 00:00:00

abstract：:A 37-year-old woman experienced painless, progressive vision loss to no light perception in the left eye over the course of 3 days. The right eye was unaffected. On examination, the only other abnormal finding was a +4 left afferent pupillary defect. She was initially diagnosed with retrobulbar optic neuritis and admi...

journal_title：Survey of ophthalmology

authors： Craenen G,Brown SM,Freedman KA,Windisch TR,Corona J

更新日期：2004-05-01 00:00:00

abstract：:Heavy eye syndrome is an important type of myopia-induced strabismus. We provide an overview of heavy eye syndrome, from its history to its most salient features. The theory of the orbital and rectus muscle pulley system as it relates to heavy eye syndrome and the prevailing theories on the pathophysiology of heavy ey...

journal_title：Survey of ophthalmology

authors： Hennein L,Robbins SL

更新日期：2021-01-01 00:00:00

abstract：:Angiogenesis is a complex biologic process that occurs normally in development and in turnover and remodeling of mature vascular networks. Pathological angiogenesis and neovascularization occur in association with retinal and ocular ischemic diseases, in retinopathy of prematurity and other developmental disorders, an...

journal_title：Survey of ophthalmology

authors： Gariano RF,Kalina RE,Hendrickson AE

更新日期：1996-05-01 00:00:00

abstract：:A case is presented of a 16-year-old anticoagulated, immunocompromised male presenting with a blind, proptotic left eye, total ophthalmoplegia, and central retinal artery occlusion. Ophthalmic examination revealed other features of the orbital apex syndrome. Mucormycosis misdiagnosed as a traumatic orbital hemorrhage ...

journal_title：Survey of ophthalmology

authors： Bray WH,Giangiacomo J,Ide CH

更新日期：1987-09-01 00:00:00

abstract：:Lysosomal enzymes are distributed widely in various ocular tissues. Among these tissues, the uvea and retina show the higher enzyme activities of acid phosphates, beta-blucuronidase, alpha-fucosidase, alpha-mannosidase, arylsulfatase, cathepsin D, cathepsin B and others. The particular role of lysosomal enzymes in the...

journal_title：Survey of ophthalmology

authors： Hayasaka S

更新日期：1983-01-01 00:00:00

abstract：:Recent advances in our understanding of the anatomy and physiology of accommodation have contributed to current concepts of the possible constituent factors in presbyopia, largely supplanting the long-held belief that presbyopia is due to sclerosis of the crystalline lens. In this review, the author examines epidemiol...

journal_title：Survey of ophthalmology

authors： Weale R

更新日期：1989-07-01 00:00:00

abstract：:It is common for healthy children with specific visual complaints to be seen for eye examinations. After a complete eye examination has ruled out pathologic conditions as the cause of these complaints, it is appropriate for the clinician to explore the possibility that normal entoptic or physiologic visual phenomena m...

journal_title：Survey of ophthalmology

authors： Wright JD Jr,Boger WP 3rd

更新日期：1999-09-01 00:00:00

abstract：:Given the recent interest in complementary and alternative medicine (CAM), some patients may seek such treatments to supplement their traditional glaucoma management. The prevalence of CAM use for glaucoma is approximately 5%. We reviewed the literature to determine the potential benefit of various alternative treatme...

journal_title：Survey of ophthalmology

authors： Rhee DJ,Katz LJ,Spaeth GL,Myers JS

更新日期：2001-07-01 00:00:00

abstract：:Phosphorus (31P) nuclear magnetic resonance (NMR) represents a noninvasive technique for the assessment of ocular metabolism. The measurement of a spectrum of phosphorus-containing metabolites (e.g., phosphorylated sugars and ATP), including a number of heretofore uncharacterized metabolites, can be made with a single...

journal_title：Survey of ophthalmology

authors： Greiner JV,Kopp SJ,Glonek T

更新日期：1985-11-01 00:00:00

abstract：:The optical considerations of intraocular lenses can be understood, using only the formulae and principles taught in a typical basic science course in ophthalmology. Some of the more common optical problems associated with intraocular lenses are presented and the methods for their solutions are illustrated and explain...

journal_title：Survey of ophthalmology

authors： Miller D

更新日期：1979-07-01 00:00:00

abstract：:Caspar Stromayr, ophthalmologist and hernia surgeon, is credited with writing the first German ophthalmic work of known authorship. Written in about 1559 as an appendix to Practica Copiosa, a larger work on hernia surgery, the ophthalmic chapters describe Stromayr's thoughts on the etiology and treatment of cataract. ...

journal_title：Survey of ophthalmology

authors： Blanchard DL

更新日期：1990-09-01 00:00:00

abstract：:Retinitis pigmentosa (RP) is a form of inherited night blindness. Over decades, various dubious treatment strategies that lacked sufficient theoretically sound underpinnings were explored. Initially they were enthusiastically promoted and subsequently discredited. It is apparent that many were predicated on the errone...

journal_title：Survey of ophthalmology

authors： Fishman GA

更新日期：2013-11-01 00:00:00

abstract：:The effects of topical adrenergic agents on the tissue circulation of the optic nerve head (ONH) were studied in animal and human eyes with use of a laser speckle tissue circulation analyzer. Drugs studied were nipradilol, a beta1-2-blocker with weak alpha-blocking and nitroglycerinlike activities; bunazosin, a select...

journal_title：Survey of ophthalmology

authors： Tamaki Y,Araie M,Tomita K,Tomidokoro A,Nagahara M

更新日期：1997-11-01 00:00:00

abstract：:The abundant data about retinal tears has shown that they are prevalent in the general population and that the vast majority of retinal tears do not lead to retinal detachment. What remains to be clarified are the criteria for identifying the few retinal breaks which require prophylactic surgery to prevent their progr...

journal_title：Survey of ophthalmology

authors： Sigelman J

更新日期：1980-09-01 00:00:00

abstract：:We report a patient with left eye positional transient visual obscurations, diplopia, a left afferent pupillary defect, and optic disk edema-all occurring during pregnancy. Noncontrast magnetic resonance imaging revealed an orbital mass encasing the optic nerve and extending through the superior orbital fissure into t...

journal_title：Survey of ophthalmology

authors： Mokhtarzadeh A,Maltry A,McClelland C

更新日期：2017-01-01 00:00:00

abstract：:Jules Gonin's former student presents a personal and historical biography of the Swiss ophthalmologist, who, between 1902 and 1921, explored and illustrated the many unknown aspects of retinal detachment, defined its pathogenesis, and developed the method of reattachment by ignipuncture and thermocautery. ...

journal_title：Survey of ophthalmology

authors： Rumpf J

更新日期：1976-11-01 00:00:00