A historical perspective on the early treatment of night blindness and the use of dubious and unproven treatment strategies for patients with retinitis pigmentosa.

Abstract:

:Retinitis pigmentosa (RP) is a form of inherited night blindness. Over decades, various dubious treatment strategies that lacked sufficient theoretically sound underpinnings were explored. Initially they were enthusiastically promoted and subsequently discredited. It is apparent that many were predicated on the erroneous assumption that the primary cause of RP was related to impairment of the retinal circulation. Herein, several of these strategies are reviewed and critiqued. Reasons why clinicians may have been deceived into overzealous interpretations of their treatment methods are explored. The examples disclosed should serve as a note of caution for current investigators to guard against self-deception when exploring newly developed treatment strategies.

journal_name

Surv Ophthalmol

journal_title

Survey of ophthalmology

authors

Fishman GA

doi

10.1016/j.survophthal.2013.04.002

subject

Has Abstract

pub_date

2013-11-01 00:00:00

pages

652-63

issue

6

eissn

0039-6257

issn

1879-3304

pii

S0039-6257(13)00087-8

journal_volume

58

pub_type

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