Cyclo-oxygenase inhibitors in ophthalmology.

Abstract:

:Cyclo-oxygenase inhibitors, which are formulated as ophthalmic eyedrop preparations, have recently become commercially available for use by ophthalmologists in the United States to inhibit intraoperative miosis during cataract surgery and to prevent postoperative inflammation. In addition, they are available worldwide as ocular antiinflammatory drugs and are used in the prevention and treatment of pseudophakic and aphakic cystoid macular edema. Understanding the rationale behind the use of these agents requires an understanding of the pathophysiology of the cyclo-oxygenase inhibitors. In this review recent advances in laboratory and clinical science are emphasized. The role of COIs during and following surgery is examined.

journal_name

Surv Ophthalmol

journal_title

Survey of ophthalmology

authors

Flach AJ

doi

10.1016/0039-6257(92)90095-b

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

259-84

issue

4

eissn

0039-6257

issn

1879-3304

pii

0039-6257(92)90095-B

journal_volume

36

pub_type

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