Abstract：
:Oxidative stress is one of the main mechanisms of lens opacification, and certain nutritional antioxidants are suspected to have a protective effect. To examine the role of these nutritional antioxidants on cataract prevention, we searched major databases and reviewed current evidence regarding the protective effect of nutritive antioxidants. We included observational studies that investigate the association between one or more of the following micronutrients and cataract: vitamin A, vitamin C, vitamin E, lutein, zeaxanthin, α- and β-carotene. Two independent authors extracted data and assessed their quality. We pooled results for overall cataract incidence for all types of cataract and separately for nuclear, cortical, and posterior subcapsular cataract. We did not perform sensitivity analysis. Twenty-five studies were included in the qualitative and 24 in the quantitative part of the study, with a total of 295,821 participants over 30 years old. Results from pooled analysis showed a protective effect of antioxidants on cataract, but not all of them reached statistical significance. Statistically significant results were reached for vitamin C (odds ratio [OR] = 0.88, 95% confidence interval [CI] [0.81, 0.97]), beta-carotene (OR = 0.89, 95% CI [0.83, 0.95]), and lutein and zeaxanthin (OR = 0.92, 95% CI [0.85, 0.99]). We did not find statistically significant results for vitamin E (OR = 0.84, 95% CI [0.70, 1.01]), vitamin A (OR = 0.90, 95% CI [0.80, 1.00]), or alpha-carotene (OR = 0.92, 95% CI [0.85, 1.00]). The present study shows a relation between certain antioxidants and cataract, but further studies, especially interventional, are needed to confirm this hypothesis.
journal_name
Surv Ophthalmoljournal_title
Survey of ophthalmologyauthors
Sideri O,Tsaousis KT,Li HJ,Viskadouraki M,Tsinopoulos ITdoi
10.1016/j.survophthal.2019.03.003subject
Has Abstractpub_date
2019-01-01 00:00:00pages
668-678issue
5eissn
0039-6257issn
1879-3304pii
S0039-6257(18)30161-9journal_volume
64pub_type
杂志文章,meta分析abstract：:The clinical syndrome of divergence paralysis has been described since the mid 19th century. Speculation still surrounds the possible existence of an anatomical center for divergence function. Our report explores this possibility and describes the magnetic resonance images of a patient with a unilateral 6th nerve pals...
journal_title：Survey of ophthalmology
pub_type： 杂志文章
doi：10.1016/0039-6257(86)90094-9
更新日期：1986-05-01 00:00:00
abstract：:A 20-year-old Hispanic man with Down syndrome presented with progressively worsening headache, fluctuating decreased vision, and bilateral optic disk edema. Magnetic resonance imaging of the head showed an empty sella, and magnetic resonance venography showed thrombosis of left transverse and sigmoid sinuses. Catheter...
journal_title：Survey of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.survophthal.2012.10.005
更新日期：2013-11-01 00:00:00
abstract：:Adjunctive therapy for the management of glaucoma is commonly used. Unfixed combinations of the prostaglandin analog latanoprost and other glaucoma medications have been demonstrated to effectively lower intraocular pressure (IOP). The range of reported additional reductions in IOP compared to a monotherapy baseline a...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/s0039-6257(02)00295-3
更新日期：2002-08-01 00:00:00
abstract：:Glaucomatous optic neuropathy implies loss of retinal ganglion cells, including their axons, and a major tissue remodeling, especially in the optic nerve head. Although increased intraocular pressure is a major risk factor for glaucomatous optic neuropathy, there is little doubt that other factors such as ocular blood...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.survophthal.2008.06.006
更新日期：2008-09-01 00:00:00
abstract：:Drugs across many pharmacologic classes induce corneal epithelial changes. Many of these drugs have cationic amphiphilic structures, with a hydrophobic ring and hydrophilic cationic amine side chain that allow them to cross cell membranes. These drugs lead to intracellular phospholipid accumulation, often manifested i...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.survophthal.2016.11.008
更新日期：2017-01-01 00:00:00
abstract：:Recent advances in our understanding of the anatomy and physiology of accommodation have contributed to current concepts of the possible constituent factors in presbyopia, largely supplanting the long-held belief that presbyopia is due to sclerosis of the crystalline lens. In this review, the author examines epidemiol...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/0039-6257(89)90126-4
更新日期：1989-07-01 00:00:00
abstract：:Invasive mucoepidermoid carcinoma of the conjunctiva of the left lower eyelid was diagnosed in an orbital exenteration specimen of a 57-year-old woman, after a biopsy of the same lesion was originally diagnosed as invasive squamous cell carcinoma. The woman was undergoing mitomycin C injections for ocular cicatricial ...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.survophthal.2006.06.012
更新日期：2006-09-01 00:00:00
abstract：:The light and electron microscopic findings are reviewed in two patients who had eyes enucleated for peripheral choroidal malignant melanomas. Preoperatively, cystoid macular edema was documented by fluorescein angiography in the melanoma-containing eye in both patients. Intracytoplasmic swelling (edema) of the Müller...
journal_title：Survey of ophthalmology
pub_type： 杂志文章
doi：10.1016/0039-6257(84)90233-9
更新日期：1984-05-01 00:00:00
abstract：:This review focuses on the features of pseudotumor cerebri in the pediatric age group. There is no sex predilection in children, and obesity does not appear to be an important factor. Infants and young children may present with irritability, apathy, or somnolence, rather than headache. Dizziness and ataxia may also oc...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/0039-6257(92)90134-f
更新日期：1992-11-01 00:00:00
abstract：:A 74-year-old woman experienced chronic painless progressive binocular horizontal diplopia for 2 years. Initial examination showed a visual acuity of 20/20 OU. External and slit lamp examination was unremarkable. Orthoptic evaluation showed an incomitant esotropia, a small vertical strabismus, and a large degree of ex...
journal_title：Survey of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.survophthal.2018.10.006
更新日期：2019-01-01 00:00:00
abstract：:The ocular posterior segment manifestations of AIDS may be divided into four categories: retinal vasculopathy, unusual malignancies, neuro-ophthalmologic abnormalities, and opportunistic infections. Microvasculopathy is the most common manifestation. Opportunistic infections, particularly cytomegalovirus retinitis and...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.survophthal.2003.12.008
更新日期：2004-03-01 00:00:00
abstract：:Optic disk imaging is integral to the diagnosis and treatment of patients with glaucoma. We discuss the various forms of imaging the optic nerve, including ophthalmoscopy, photography, and newer imaging modalities, including optical coherence tomography (OCT), confocal scanning laser ophthalmoscopy (HRT), and scanning...
journal_title：Survey of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.survophthal.2013.10.004
更新日期：2014-07-01 00:00:00
abstract：:The pathogenesis of many anterior segment disorders and ocular complications following surgery are secondary to the wound healing response. The extent of clinical damage observed is closely related to the amount of scarring and tissue contraction. Matrix metalloproteinases (MMPs) are a family of enzymes that play a vi...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/s0039-6257(02)00287-4
更新日期：2002-05-01 00:00:00
abstract：:The nonocular manifestations of parenteral drug abuse are presented to familiarize the ophthalmologist with this ever growing, medical and psychosocial problem. The ophthalmologist, like other primary care physicians, may be the first professional to encounter these patients whose substance abuse may lead to a wider s...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/0039-6257(86)90063-9
更新日期：1986-03-01 00:00:00
abstract：:There are a number of unresolved questions regarding small choroidal melanomas. At what stage in the natural history of these tumors do they develop the capacity to metastasize? What are the effects of various therapeutic modalities on the incidence of metastatic disease? Clinicopathologic studies suggest that patient...
journal_title：Survey of ophthalmology
pub_type： 杂志文章
doi：10.1016/0039-6257(78)90133-9
更新日期：1978-05-01 00:00:00
abstract：:It is common for healthy children with specific visual complaints to be seen for eye examinations. After a complete eye examination has ruled out pathologic conditions as the cause of these complaints, it is appropriate for the clinician to explore the possibility that normal entoptic or physiologic visual phenomena m...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/s0039-6257(99)00078-8
更新日期：1999-09-01 00:00:00
abstract：:The published evidence that instilled drugs can affect the blood supply to the retina and optic nerve head in humans is examined. As a background, seven techniques that have been used to measure flow are briefly described and criticized. For timolol, the corresponding measurements, obtained by a number of investigator...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/s0039-6257(02)00326-0
更新日期：2002-08-01 00:00:00
abstract：:Mitochondrial diseases frequently manifest neuro-ophthalmologic symptoms and signs. Because of the predilection of mitochondrial disorders to involve the optic nerves, extraocular muscles, retina, and even the retrochiasmal visual pathways, the ophthalmologist is often the first physician to be consulted. Disorders ca...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.survophthal.2009.10.002
更新日期：2010-07-01 00:00:00
abstract：:Endophthalmitis is a serious complication of cataract surgery that occurs in thousands of patients each year. To decrease the incidence of postoperative endophthalmitis, many surgeons inject intracameral antibiotics (cefuroxime, moxifloxacin, and vancomycin) routinely at the end of surgery. A large number of recently ...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.survophthal.2020.04.006
更新日期：2021-01-01 00:00:00
abstract：:Selective laser trabeculoplasty (SLT) is a relatively new type of laser used in treating open-angle glaucoma (OAG) and is reported to be equally efficacious to a first-line medication and argon laser trabeculoplasty (ALT). We summarize available evidence for considering SLT as an alternative treatment in OAG through s...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.survophthal.2014.06.006
更新日期：2015-01-01 00:00:00
abstract：:Based on their mechanism of action, the most frequently used ocular hypertensive agents, the beta-blockers, cannot be assumed to reduce IOP during sleep. The need for drugs that reduce IOP around-the-clock is underscored, however, by the fact that inadequate nocturnal ocular perfusion pressure is considered to be one ...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/s0039-6257(97)80021-5
更新日期：1997-02-01 00:00:00
abstract：:An analytical review of the data available in the field of phakic intraocular lens implantation was conducted. Particular attention was paid to the more critical issues of intraocular lens sizing and safety guidelines. A comprehensive, competitive analysis of different implantation sites, intraocular lens model design...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.survophthal.2005.08.011
更新日期：2005-11-01 00:00:00
abstract：:A 37-year-old woman developed red painful eyes, diarrhea, and painful oral and genital ulcerations. Optic disk swelling was noted bilaterally. Colonoscopy was significant for granulomatous lesions consistent with Crohn disease. Epidemiologic factors, diagnostic criteria, and differentiating characteristics for Behcet ...
journal_title：Survey of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.survophthal.2005.06.012
更新日期：2005-09-01 00:00:00
abstract：:Corneal transplant surgeries have a broad range of indications with outcomes largely dependent on surgeon experience. Traditional manual techniques have certain limitations pertaining to the preparation of donor tissue and the recipient bed that might affect the predictability of visual outcomes. Use of lasers for ker...
journal_title：Survey of ophthalmology
pub_type： 杂志文章
doi：10.1016/j.survophthal.2021.01.009
更新日期：2021-01-29 00:00:00
abstract：:Ocular myasthenia is a localized form of myasthenia clinically involving only the extraocular, levator palpebrae superioris, and/or orbicularis oculi muscles. Ocular manifestations can masquerade as a variety of ocular motility disorders, including cranial nerve and gaze palsies. A history of variable and fatiguable m...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/0039-6257(94)90194-5
更新日期：1994-11-01 00:00:00
abstract：:Typical optic neuritis is an idiopathic demyelinating condition that is often associated with multiple sclerosis. This has been well characterized and has an excellent prognosis. Atypical optic neuritis can result from an inflammatory, infectious, or autoimmune disorder. Differentiating the two types of optic neuritis...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/j.survophthal.2019.06.001
更新日期：2019-01-01 00:00:00
abstract：:Age-related macular degeneration (AMD) involves a progressive impairment of the outer layers in the center of the retina. Experimental studies have demonstrated that bright light preferentially damages precisely the region that degenerates in AMD. The evidence that solar radiation is responsible for some of the deteri...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/0039-6257(88)90174-9
更新日期：1988-01-01 00:00:00
abstract：:A 34-year-old man with AIDS was admitted to the hospital with a one-week history of cough, chest pain, and fever. Radiography revealed a cavitating left upper lobe lesion. Two weeks later he developed a headache associated with a contrast enhancing lesion in the right parietal lobe. The patient had a progressive downh...
journal_title：Survey of ophthalmology
pub_type： 杂志文章
doi：10.1016/s0039-6257(05)80043-8
更新日期：1994-07-01 00:00:00
abstract：:The Polymerase Chain Reaction (PCR) is a highly innovative technique which allows for the generation of large amounts of DNA starting from minute quantities obtained from the blood or tissue of a patient. With the increasing knowledge concerning the structure of the human genome and the potential to amplify specific s...
journal_title：Survey of ophthalmology
pub_type： 杂志文章,评审
doi：10.1016/s0039-6257(96)00004-5
更新日期：1997-01-01 00:00:00
abstract：:Jules Gonin's former student presents a personal and historical biography of the Swiss ophthalmologist, who, between 1902 and 1921, explored and illustrated the many unknown aspects of retinal detachment, defined its pathogenesis, and developed the method of reattachment by ignipuncture and thermocautery. ...
journal_title：Survey of ophthalmology
pub_type： 传,历史文章,杂志文章
doi：10.1016/0039-6257(76)90125-9
更新日期：1976-11-01 00:00:00
