Dual energy CT scanning for analysis of brain damage due to X-irradiation.

abstract：:Past literature has provided evidence that a normal mechanical force environment of blood flow may guide normal development while an abnormal environment can lead to congenital malformations, thus warranting further studies on embryonic cardiovascular flow dynamics. In the current study, we developed a non-invasive 4D...

journal_title：Annals of biomedical engineering

authors： Ho S,Tan GXY,Foo TJ,Phan-Thien N,Yap CH

更新日期：2017-10-01 00:00:00

abstract：:Validation is a critical step in finite element model (FEM) development. This study focuses on the validation of the Global Human Body Models Consortium full body average male occupant FEM in five localized loading regimes-a chest impact, a shoulder impact, a thoracoabdominal impact, an abdominal impact, and a pelvic ...

journal_title：Annals of biomedical engineering

authors： Vavalle NA,Davis ML,Stitzel JD,Gayzik FS

更新日期：2015-09-01 00:00:00

abstract：:The efforts to develop structural materials for biodegradable metal implants have lately shifted their focus from Magnesium and Iron base alloys towards Zinc. This was mainly due to the accelerated corrosion rate of Mg that is accompanied by hydrogen gas evolution, formation of voluminous iron oxide products with redu...

journal_title：Annals of biomedical engineering

authors： Kafri A,Ovadia S,Yosafovich-Doitch G,Aghion E

更新日期：2019-06-01 00:00:00

abstract：:The cerebral blood flow (CBF) response to changes in perfusion pressure mediated through decreases in arterial pressure, increases in cerebrospinal fluid (CSF) pressure and increases in jugular venous pressure was studied in anesthetized dogs. A preparation was developed in which each of the three relevant pressures c...

journal_title：Annals of biomedical engineering

authors： Wagner EM,Traystman RJ

更新日期：1985-01-01 00:00:00

abstract：:The contractile power of the latissimus dorsi muscle (LDM) is used in skeletal muscle cardiac assist (SMCA) to augment the blood pumping ability of a failing heart. The LDM has three anatomically distinct, independently innervate segments-the transverse, oblique, and lateral. There are potential advantages to selectiv...

journal_title：Annals of biomedical engineering

authors： Thompson DR,Michele JJ,Cheever EA,George DT

更新日期：1999-01-01 00:00:00

abstract：:Currently, there are no clinically available tools or applications which could predict osteoarthritis development. Some computational models have been presented to simulate cartilage degeneration, but they are not clinically feasible due to time required to build subject-specific knee models. Therefore, the objective ...

journal_title：Annals of biomedical engineering

authors： Mononen ME,Liukkonen MK,Korhonen RK

更新日期：2019-03-01 00:00:00

abstract：:Previous research in cellular adhesion has focused primarily on studying isolated cells under conditions where cells do not interact with each other. However, in vivo cells form sheets where both cell-substratum and cell-cell interactions contribute to the overall adhesive behavior. Our understanding of how cell-cell ...

journal_title：Annals of biomedical engineering

authors： Peel MM,DiMilla PA

更新日期：1999-03-01 00:00:00

abstract：:For treatment of complex congenital heart disease, computer simulation using a three-dimensional heart model may help to improve outcomes by enabling detailed preoperative evaluations. However, no highly integrated model that accurately reproduces a patient's pathophysiology, which is required for this simulation has ...

journal_title：Annals of biomedical engineering

authors： Kariya T,Washio T,Okada JI,Nakagawa M,Watanabe M,Kadooka Y,Sano S,Nagai R,Sugiura S,Hisada T

更新日期：2020-06-01 00:00:00

abstract：:For highly diffusive solutes the kinetics of blood-tissue exchange is only poorly represented by a model consisting of sets of independent parallel capillary-tissue units. We constructed a more realistic multicapillary network model conforming statistically to morphometric data. Flows through the tortuous paths in the...

journal_title：Annals of biomedical engineering

authors： Beard DA,Bassingthwaighte JB

更新日期：2000-03-01 00:00:00

abstract：:Rapid technological advances have prompted the development of a wide range of telemonitoring systems to enable the prevention, early diagnosis and management, of chronic conditions. Remote monitoring can reduce the amount of recurring admissions to hospital, facilitate more efficient clinical visits with objective res...

journal_title：Annals of biomedical engineering

authors： Ní Scanaill C,Carew S,Barralon P,Noury N,Lyons D,Lyons GM

更新日期：2006-04-01 00:00:00

abstract：:Premature ovarian insufficiency (POI) is a major complication of cytotoxic treatments due to extreme ovarian sensitivity to chemotherapy and radiation. In pediatric cancer patients modern therapy has improved the long-term survival to over 80% in the United States. However, these cancer survivors face long-term health...

journal_title：Annals of biomedical engineering

authors： David A,Day JR,Cichon AL,Lefferts A,Cascalho M,Shikanov A

更新日期：2017-07-01 00:00:00

abstract：:Soft collagenous tissue features many hierarchies of structure, starting from tropocollagen molecules that form fibrils, and proceeding to a bundle of fibrils that form fibers. Here we report the development of an atomistically informed continuum model of collagenous tissue. Results from full atomistic and molecular m...

journal_title：Annals of biomedical engineering

authors： Tang H,Buehler MJ,Moran B

更新日期：2009-06-01 00:00:00

abstract：:We seek to construct physical and mathematical models of life. Such models allow us to test our understanding of how living systems function and how they respond to human imposed stimuli. One system is a genomically and chemically complete model of a minimal cell. This cell is a hypothetical bacterium with the fewest ...

journal_title：Annals of biomedical engineering

authors： Shuler ML

更新日期：2012-07-01 00:00:00

abstract：:The identification of the input to, or kernels of, a system using nonparametric representations and least-squares estimation is becoming increasingly popular. Nonparametric representations avoid making a priori assumptions about the input or having detailed knowledge about the system, and only need to guarantee known ...

journal_title：Annals of biomedical engineering

authors： Verotta D

更新日期：1998-09-01 00:00:00

abstract：:Dexterity of robots is highly required when it comes to integration for medical applications. Major efforts have been conducted to increase the dexterity at the distal parts of medical robots. This paper reports on developments toward integrating biocompatible conducting polymers (CP) into inherently dexterous concent...

journal_title：Annals of biomedical engineering

authors： Chikhaoui MT,Benouhiba A,Rougeot P,Rabenorosoa K,Ouisse M,Andreff N

更新日期：2018-10-01 00:00:00

abstract：:We describe a system for real-time control of biological and other experiments. This device, based around the Real-Time Linux operating system, was tested specifically in the context of dynamic clamping, a demanding real-time task in which a computational system mimics the effects of nonlinear membrane conductances in...

journal_title：Annals of biomedical engineering

authors： Dorval AD,Christini DJ,White JA

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:We present a fundamental theoretical framework for analysis of energy dissipation in any component of the circulatory system and formulate the full energy budget for both venous and arterial circulations. New indices allowing disease-specific subject-to-subject comparisons and disease-to-disease hemodynamic ...

journal_title：Annals of biomedical engineering

authors： Dasi LP,Pekkan K,de Zelicourt D,Sundareswaran KS,Krishnankutty R,Delnido PJ,Yoganathan AP

更新日期：2009-04-01 00:00:00

abstract：:This study evaluates the use of artificial neural networks to estimate stroke volume from pre-processed, thoracic impedance plethysmograph signals from 20 healthy subjects. Standard back-propagation was used to train the networks, with Doppler stroke volume estimates as the desired output. The trained networks were th...

journal_title：Annals of biomedical engineering

authors： Mulavara AP,Timmons WD,Nair MS,Gupta V,Kumar AA,Taylor BC

更新日期：1998-07-01 00:00:00

abstract：:Measurement of cell shortening is an important technique for assessment of physiology and pathophysiology of cardiac myocytes. Many types of heart disease are associated with decreased myocyte shortening, which is commonly caused by structural and functional remodeling. Here, we present a new approach for local measur...

journal_title：Annals of biomedical engineering

authors： Lichter J,Li H,Sachse FB

更新日期：2016-10-01 00:00:00

abstract：:This article presents a multi-scale computational model describing the transport of water vapor and heat within the human conducting airways and its interaction with cellular fluid transport kinetics. This tight coupling between the cell and the evaporative flux allows the periciliary liquid (PCL) depth to be investig...

journal_title：Annals of biomedical engineering

authors： Warren NJ,Crampin EJ,Tawhai MH

更新日期：2010-12-01 00:00:00

abstract：:The false vocal folds are believed to be components of the acoustic filter that is responsible for shaping the voice. However, the effects of false vocal folds on the vocal fold vibration and the glottal aerodynamic during phonation remain unclear. This effect has implications for computational modeling of phonation a...

journal_title：Annals of biomedical engineering

authors： Zheng X,Bielamowicz S,Luo H,Mittal R

更新日期：2009-03-01 00:00:00

abstract：:There is a significant clinical need for engineered bone graft substitutes that can quickly, effectively, and safely repair large segmental bone defects. One emerging field of interest involves the growth of engineered bone tissue in vitro within bioreactors, the most promising of which are perfusion bioreactors. Usin...

journal_title：Annals of biomedical engineering

authors： Ball O,Nguyen BB,Placone JK,Fisher JP

更新日期：2016-12-01 00:00:00

abstract：:The aim of this study was to establish in vitro bench-tests of left atrial appendage occlusion (LAAo) devices regarding tug force, radial force and sealing capacity. Two LAAo devices, namely the WATCHMAN™ and the Occlutech®, of three different sizes underwent testing in novel dedicated in vitro setups. Radial force wa...

journal_title：Annals of biomedical engineering

authors： Menne MF,Schrickel JW,Nickenig G,Al-Kassou B,Nelles D,Schmitz-Rode T,Steinseifer U,Sedaghat A

更新日期：2018-09-01 00:00:00

abstract：:Continuous gradients exist at osteochondral interfaces, which may be engineered by applying spatially patterned gradients of biological cues. In the present study, a protein-loaded microsphere-based scaffold fabrication strategy was applied to achieve spatially and temporally controlled delivery of bioactive signals i...

journal_title：Annals of biomedical engineering

authors： Dormer NH,Singh M,Wang L,Berkland CJ,Detamore MS

更新日期：2010-06-01 00:00:00

abstract：:Acute cerebral ischemic events and thrombosis are associated with the rupture/erosion of carotid atherosclerotic plaques. The aim of the present study was to determine the impact of calcification deposition on the wall shear stress (WSS) and stresses within the plaques using 3D fluid-structure interaction (FSI) models...

journal_title：Annals of biomedical engineering

authors： Benitez J,Fontanarosa D,Wang J,Paritala PK,McGahan T,Lloyd T,Li Z

更新日期：2020-10-20 00:00:00

abstract：:While viscoelastic responses of isolated trunk soft tissues have been characterized in earlier studies, the effects of external loading and flexion rate on these responses in the intact human trunk are largely unknown. Two experiments were conducted to measure trunk viscoelastic behaviors, one involving prolonged flex...

journal_title：Annals of biomedical engineering

authors： Toosizadeh N,Nussbaum MA

更新日期：2013-06-01 00:00:00

abstract：:It is well known that neutrophils take much longer to traverse the pulmonary capillary bed than erythrocytes, and this is likely due to differences in the structure and rheology of the cells. In this study, we simulate the transit of a neutrophil in a capillary using a Newtonian drop model and a viscoelastic drop mode...

journal_title：Annals of biomedical engineering

authors： Zhou C,Yue P,Feng JJ

更新日期：2007-05-01 00:00:00

abstract：:Potential human and environmental hazards resulting from the exposure of living organisms to silver nanoparticles (Ag NPs) have been the subject of intensive discussion in the last decade. Despite the growing use of Ag NPs in biomedical applications, a quantification of the toxic effects as a function of the total sil...

journal_title：Annals of biomedical engineering

authors： Poli D,Mattei G,Ucciferri N,Ahluwalia A

更新日期：2020-04-01 00:00:00

abstract：:Deformational loading represents a primary component of the chondrocyte physical environment in vivo. This review summarizes our experience with physiologic deformational loading of chondrocyte-seeded agarose hydrogels to promote development of cartilage constructs having mechanical properties matching that of the par...

journal_title：Annals of biomedical engineering

authors： Hung CT,Mauck RL,Wang CC,Lima EG,Ateshian GA

更新日期：2004-01-01 00:00:00

abstract：:In this work, we propose an analog electrical model of the coronary circulation for patients with obstructive disease undergoing revascularization. In this clinical situation, the collateral circulation to the occluded artery is difficult to ascertain via preoperative measurements and well-developed collaterals might ...

journal_title：Annals of biomedical engineering

authors： Maasrani M,Verhoye JP,Corbineau H,Drochon A

更新日期：2008-07-01 00:00:00