Quantitative Validation of a Human Body Finite Element Model Using Rigid Body Impacts.

abstract：:This study evaluates the use of artificial neural networks to estimate stroke volume from pre-processed, thoracic impedance plethysmograph signals from 20 healthy subjects. Standard back-propagation was used to train the networks, with Doppler stroke volume estimates as the desired output. The trained networks were th...

journal_title：Annals of biomedical engineering

authors： Mulavara AP,Timmons WD,Nair MS,Gupta V,Kumar AA,Taylor BC

更新日期：1998-07-01 00:00:00

abstract：:Intramuscular pressure (IMP) shows promise for estimating individual muscle tension in vivo. However, previous pressure measurements show high variability during isometric contraction and poor correlation with tension during dynamic contraction. We hypothesized that enhanced sensor anchoring/orientation would improve ...

journal_title：Annals of biomedical engineering

authors： O'Connor SM,Kaufman KR,Ward SR,Lieber RL

更新日期：2021-02-01 00:00:00

abstract：:We propose a multifrequency energy transmission scheme for annular phased arrays in deep-body hyperthermia. The problem of frequency dependent resonance effects reported in hyperthermia phantom calibration studies, leading to skewed energy deposition patterns and unwanted energy maxima (hot spots), is addressed by com...

journal_title：Annals of biomedical engineering

authors： Jacobsen S,Melandsø F

更新日期：2002-01-01 00:00:00

abstract：:A model predictive control strategy to simultaneously regulate hemodynamic and anesthetic variables in critical care patients is presented. A nonlinear canine circulatory model, which has been used to study the effect of inotropic and vasoactive drugs on hemodynamic variables, has been extended to include propofol pha...

journal_title：Annals of biomedical engineering

authors： Rao RR,Bequette BW,Roy RJ

更新日期：2000-01-01 00:00:00

abstract：:The most widely implanted prosthetic valve is the mechanical bileaflet. Recent clinical experiences suggest that some designs are more prone to thromboembolic episodes than others. This study evaluated the hinge flow and near-field forward flow of the new St. Jude Medical Regent bileaflet mechanical heart valve. Laser...

journal_title：Annals of biomedical engineering

authors： Ellis JT,Travis BR,Yoganathan AP

更新日期：2000-05-01 00:00:00

abstract：:A novel in vitro culture system of organotypic human skin explants interfacing with external fixator pins is presented. The system was used to observe changes in skin morphology on the skin at the pin interface. To evaluate the performance of this novel system, histological analysis of human skin explants cultured for...

journal_title：Annals of biomedical engineering

authors： Peramo A,Marcelo CL,Goldstein SA,Martin DC

更新日期：2009-02-01 00:00:00

abstract：:Additive manufacturing, also known as 3D printing, has emerged over the past 3 decades as a disruptive technology for rapid prototyping and manufacturing. Vat polymerization, powder bed fusion, material extrusion, and binder jetting are distinct technologies of additive manufacturing, which have been used in a wide va...

journal_title：Annals of biomedical engineering

authors： Trombetta R,Inzana JA,Schwarz EM,Kates SL,Awad HA

更新日期：2017-01-01 00:00:00

abstract：:A method of investigating head acceleration and intracranial dynamics from stick impacts in girls' and women's lacrosse was developed using headform impact experiments and a finite element head model. Assessing the likelihood of head injury due to stick-head impacts is of interest in girls' and women's lacrosse due to...

journal_title：Annals of biomedical engineering

authors： Morse JD,Franck JA,Wilcox BJ,Crisco JJ,Franck C

更新日期：2014-12-01 00:00:00

abstract：:Human stem cells hold significant potential for the treatment of various diseases. However, their use as a therapy is hampered because of limited understanding of the mechanisms by which they respond to environmental stimuli. Efforts to understand extracellular biophysical cues have demonstrated the critical roles of ...

journal_title：Annals of biomedical engineering

authors： Piroli ME,Jabbarzadeh E

更新日期：2018-06-01 00:00:00

abstract：:A flow diverter (FD) is a flexible, densely braided stent-mesh device placed endoluminally across an intracranial aneurysm to induce its thrombotic occlusion. FD treatment planning using computational virtual stenting and flow simulation requires accurate representation of the expanded FD geometry. We have recently de...

journal_title：Annals of biomedical engineering

authors： Ma D,Dumont TM,Kosukegawa H,Ohta M,Yang X,Siddiqui AH,Meng H

更新日期：2013-10-01 00:00:00

abstract：:In physiological conditions, joint function involves continuously moving contact areas over the tissue surface. Such moving contacts play an important role for the durability of the tissue. It is known that in pathological joints these motion paths and contact mechanics change. Nevertheless, limited information exists...

journal_title：Annals of biomedical engineering

authors： Schätti OR,Gallo LM,Torzilli PA

更新日期：2016-08-01 00:00:00

abstract：:Coronary artery bypass graft (CABG) failure has been linked to graft hemodynamics, in particular wall shear stress. This study characterizes the morphology, geometry and wall shear stress patterns in human CABGs. The intimal thickness (IT) in 49 human saphenous vein CABGs was measured by digital light microscopy. The ...

journal_title：Annals of biomedical engineering

authors： Leask RL,Butany J,Johnston KW,Ethier CR,Ojha M

更新日期：2005-03-01 00:00:00

abstract：:An intelligent multichannel stimulator (IMS) has been designed and built for use in a cardiac research environment. The device is capable of measuring and responding to cardiac electrophysiological phenomena in real time with carefully timed and placed electrical stimuli. The system consists of 16 channels of sense/st...

journal_title：Annals of biomedical engineering

authors： Johnson PL,Newton JC,Rollins DL,Knisley SB,Ideker RE,Smith WM

更新日期：2002-02-01 00:00:00

abstract：:A comparison was made between turbulence calculated by subtracting an ensemble average from the instantaneous velocity and calculations made with a high pass digital filter. Velocity was measured with a laser Doppler anemometer in vitro in the region of a normal porcine aortic valve and in patients with a hot film ane...

journal_title：Annals of biomedical engineering

authors： Walburn FJ,Sabbah HN,Stein PD

更新日期：1983-01-01 00:00:00

abstract：:The emerging field of micro-technology has opened up new possibilities for exploring cellular chemotaxis in real space and time, and at single cell resolution. Chemotactic cells sense and move in response to chemical gradients and play important roles in a number of physiological and pathological processes, including ...

journal_title：Annals of biomedical engineering

authors： Kim BJ,Wu M

更新日期：2012-06-01 00:00:00

abstract：:Arteries are composed of multiple constituents that endow the wall with proper structure and function. Many vascular diseases are associated with prominent mechanical and biological alterations in the wall constituents. In this study, planar biaxial tensile test data of elastase-treated porcine aortic tissue (Chow et ...

journal_title：Annals of biomedical engineering

authors： Zeinali-Davarani S,Chow MJ,Turcotte R,Zhang Y

更新日期：2013-07-01 00:00:00

abstract：:Hemodynamic forces are known to be able to induce an inflammatory phenotype in endothelial cells (ECs). The EC glycocalyx (GCX) is a dynamic structure which is regulated in response to different stimuli and hypothesized as an important contributor to the mechanotransduction of wall shear stresses (WSS). In this work, ...

journal_title：Annals of biomedical engineering

authors： Cooper S,McDonald K,Burkat D,Leask RL

更新日期：2017-09-01 00:00:00

abstract：:Thorax injuries mainly due to rib fractures have been associated with high rates of morbidity and mortality in motor vehicle crashes. Thoracic biomechanics has been studied extensively, but there are no robust biomechanical response targets for ribs that consider age, sex, body size, and vulnerability factors. The obj...

journal_title：Annals of biomedical engineering

authors： Kang YS,Kwon HJ,Stammen J,Moorhouse K,Agnew AM

更新日期：2021-02-01 00:00:00

abstract：:The cerebral blood flow (CBF) response to changes in perfusion pressure mediated through decreases in arterial pressure, increases in cerebrospinal fluid (CSF) pressure and increases in jugular venous pressure was studied in anesthetized dogs. A preparation was developed in which each of the three relevant pressures c...

journal_title：Annals of biomedical engineering

authors： Wagner EM,Traystman RJ

更新日期：1985-01-01 00:00:00

abstract：:This study investigated the effect of mechanical strain on solute diffusion in human TMJ discs (mean cadaver age 77.8) using the electrical conductivity method. The electrical conductivity, as well as small ion diffusivity, of male and female TMJ discs was determined under three compressive strains. In the male group,...

journal_title：Annals of biomedical engineering

authors： Wright GJ,Kuo J,Shi C,Bacro TR,Slate EH,Yao H

更新日期：2013-11-01 00:00:00

abstract：:In this study, we introduce the fast wavelet transform as a method for characterizing maturational changes in electrocortical activity, respiratory activity, and blood pressure in fetal lambs in early (110-122 days), mid (123-135 days), and late (136-144 days) third trimester (term 145 days). Each recording was 2 hr i...

journal_title：Annals of biomedical engineering

authors： Akay M,Szeto HH

更新日期：1995-09-01 00:00:00

abstract：:The neutrophil has developed into one of the most efficient vertebrate motile cells. It migrates through tissues, where it encounters multiple chemoattractant signals with complex spatial and temporal characteristics. The directional movement of the neutrophil is signaled by the binding of chemoattractants and chemoki...

journal_title：Annals of biomedical engineering

authors： Zhelev DV,Alteraifi A

更新日期：2002-03-01 00:00:00

abstract：:In this study we present a novel, robust method to couple finite element (FE) models of cardiac mechanics to systems models of the circulation (CIRC), independent of cardiac phase. For each time step through a cardiac cycle, left and right ventricular pressures were calculated using ventricular compliances from the FE...

journal_title：Annals of biomedical engineering

authors： Kerckhoffs RC,Neal ML,Gu Q,Bassingthwaighte JB,Omens JH,McCulloch AD

更新日期：2007-01-01 00:00:00

abstract：:We propose a new method for guiding catheter ablation procedures to abolish sites of origin of arrhythmias. This method models both cardiac electrical activity and current pulses delivered from the tip of the ablation catheter with a single equivalent moving dipole (SEMD). The SEMD parameters are obtained from analysi...

journal_title：Annals of biomedical engineering

authors： Armoundas AA,Feldman AB,Mukkamala R,Cohen RJ

更新日期：2003-05-01 00:00:00

abstract：:As a human grows from birth to adulthood, both airway anatomy and breathing conditions vary, altering the deposition rate and pattern of inhaled aerosols. However, deposition studies have typically focused on adult subjects, results of which may not be readily extrapolated to children. This study numerically evaluated...

journal_title：Annals of biomedical engineering

authors： Xi J,Berlinski A,Zhou Y,Greenberg B,Ou X

更新日期：2012-12-01 00:00:00

abstract：:Vascular diseases are an increasing health issue, and common alloplastic, allogenic or autologous vascular grafts show frequent complications. The aim of this study is to develop an acellular, xenogenic bypass-graft from a bovine carotid artery (BAC) using detergent-based protocols. We compared decellularization with ...

journal_title：Annals of biomedical engineering

authors： Daugs A,Hutzler B,Meinke M,Schmitz C,Lehmann N,Markhoff A,Bloch O

更新日期：2017-11-01 00:00:00

abstract：:Conventional histologic methods provide valuable information regarding the physical nature of damage in fatigue-loaded tendons, limited to thin, two-dimensional sections. We introduce an imaging method that characterizes tendon microstructure three-dimensionally and develop quantitative, spatial measures of damage for...

journal_title：Annals of biomedical engineering

authors： Fung DT,Sereysky JB,Basta-Pljakic J,Laudier DM,Huq R,Jepsen KJ,Schaffler MB,Flatow EL

更新日期：2010-05-01 00:00:00

abstract：:During the fetal-to-neonatal transition, transvalvular pressures (TVPs) on the aortic and pulmonary valves change dramatically-but differently for each valve. We have examined changes in the molecular stability and crosslinking of collagen during this transition. Aortic and pulmonary valves were harvested from fetal a...

journal_title：Annals of biomedical engineering

authors： Aldous IG,Lee JM,Wells SM

更新日期：2010-09-01 00:00:00

abstract：:Potential human and environmental hazards resulting from the exposure of living organisms to silver nanoparticles (Ag NPs) have been the subject of intensive discussion in the last decade. Despite the growing use of Ag NPs in biomedical applications, a quantification of the toxic effects as a function of the total sil...

journal_title：Annals of biomedical engineering

authors： Poli D,Mattei G,Ucciferri N,Ahluwalia A

更新日期：2020-04-01 00:00:00

abstract：:Analysis and classification of esophageal motility records were investigated using signal processing and fuzzy-set pattern recognition techniques. A set of parameters has been extracted from the raw records and has previously been used as characterizing features. Improvements to these procedures were obtained by extra...

journal_title：Annals of biomedical engineering

authors： Abou-Chadi FE,Ezzat FA,Sif el-Din AA

更新日期：1994-01-01 00:00:00