Breathing resistance and ultrafine particle deposition in nasal-laryngeal airways of a newborn, an infant, a child, and an adult.

abstract：:High density particle image velocimetry, with spatial resolution of O(1 mm), was used to measure the effect of occluder rebound on the flow field near a Bjork-Shiley Monostrut tilting-disk mitral valve. The ability to measure two velocity components over an entire plane simultaneously provides a very different insight...

journal_title：Annals of biomedical engineering

authors： Kini V,Bachmann C,Fontaine A,Deutsch S,Tarbell JM

更新日期：2000-04-01 00:00:00

abstract：:Intra-cardiac flow has been explored for decades but there is still no consensus on whether or not healthy left ventricles (LV) may harbour turbulent-like flow despite its potential physiological and clinical relevance. The purpose of this study is to elucidate if a healthy LV could harbour flow instabilities, using i...

journal_title：Annals of biomedical engineering

authors： Chnafa C,Mendez S,Nicoud F

更新日期：2016-11-01 00:00:00

abstract：:This paper presents two related methods for registering an image of an anatomical object with data from sensors arranged on the object. One method is described with reference to a test case involving a rectangular electrode plaque disposed on a heart surface, which is imaged with MRI. Data from the electrodes is fused...

journal_title：Annals of biomedical engineering

authors： Hopenfeld B,Ashikaga H,McVeigh ER

更新日期：2007-10-01 00:00:00

abstract：:Statistical methods are increasingly used in biomechanics for studying bone geometry, bone density distribution and function in the population. However, relating population-based bone variation to strain during activity is computationally challenging. Here, we describe a new method for calculating strain in a populati...

journal_title：Annals of biomedical engineering

authors： Ziaeipoor H,Taylor M,Martelli S

更新日期：2020-06-01 00:00:00

abstract：:We compare the influence of time-frequency methods on analysis of time-varying renal autoregulation properties. Particularly, we examine if detection probabilities are similar for amplitude and frequency modulation for a modulated simulation signal among five time-frequency approaches, and if time-varying changes in s...

journal_title：Annals of biomedical engineering

authors： Scully CG,Siu KL,Cupples WA,Braam B,Chon KH

更新日期：2013-01-01 00:00:00

abstract：:Defibrillation efficacy testing is a common procedure at defibrillator implantation, with the objective to ensure that each patient receives a system with adequate shock efficacy. In this study, defibrillation shock efficacy as a function of shock energy was modeled by a dose response relationship. The frequency distr...

journal_title：Annals of biomedical engineering

authors： Smits K,Virag N

更新日期：2010-04-01 00:00:00

abstract：:Presented is a discussion of steps towards the creation of a database of the microcirculation encompassing anatomical and functional experimental data, and conceptual and computational models. The discussion includes issues of database utility, organization, data deposition, and linkage to other databases. The databas...

journal_title：Annals of biomedical engineering

authors： Popel AS,Greene AS,Ellis CG,Ley KF,Skalak TC,Tonellato PJ

更新日期：1998-11-01 00:00:00

abstract：:Early intervention programs aim at improving cognitive and motor outcomes of preterm infants. Intensive custom-tailored training activities are usually accompanied by assessment procedures, which have shortcomings, such as subjectivity, complex setups, and need for structured environments. A novel sensorized system, c...

journal_title：Annals of biomedical engineering

authors： Rihar A,Sgandurra G,Beani E,Cecchi F,Pašič J,Cioni G,Dario P,Mihelj M,Munih M

更新日期：2016-12-01 00:00:00

abstract：:Poor prosthetic fit is often the result of heterotopic ossification (HO), a frequent problem following blast injuries for returning service members. Osseointegration technology offers an advantage for individuals with significant HO and poor socket tolerance by using direct skeletal attachment of a prosthesis to the d...

journal_title：Annals of biomedical engineering

authors： Isaacson BM,Stinstra JG,MacLeod RS,Pasquina PF,Bloebaum RD

更新日期：2010-09-01 00:00:00

abstract：:The aim of this study was to develop an empirical model of parameter-based gait data, based on an artificial neural network and a genetic algorithm, for the assessment of patients after ankle arthrodesis. Ground reaction force vectors were measured by force platforms during level walking. Nine force parameters express...

journal_title：Annals of biomedical engineering

authors： Wu WL,Su FC,Cheng YM,Chou YL

更新日期：2001-01-01 00:00:00

abstract：:While viscoelastic responses of isolated trunk soft tissues have been characterized in earlier studies, the effects of external loading and flexion rate on these responses in the intact human trunk are largely unknown. Two experiments were conducted to measure trunk viscoelastic behaviors, one involving prolonged flex...

journal_title：Annals of biomedical engineering

authors： Toosizadeh N,Nussbaum MA

更新日期：2013-06-01 00:00:00

abstract：:Impedance data, e.g., system responses, from perturbing small amplitude applied sinusoid signals of near DC to high kilohertz frequencies, give chemical information. Analysis of frequency-dependent imaginary and real impedance proceeds from equivalent analog circuit elements to chemical and physical significance deter...

journal_title：Annals of biomedical engineering

authors： Buck RP

更新日期：1992-01-01 00:00:00

abstract：:Knowledge of strain-rate sensitivity of soft tissue viscoelastic and nonlinear elastic properties is important for accurate predictions of biomechanical behavior and for quantitative assessment of the effects of disease or surgical/pharmaceutical intervention. Soft tissues are known to exhibit mild rate sensitivity, b...

journal_title：Annals of biomedical engineering

authors： Doehring TC,Carew EO,Vesely I

更新日期：2004-02-01 00:00:00

abstract：:Rod photoreceptors express a unique type of noninactivating potassium channels, Kx channels, which play an important role in setting the dark potential and participate in shaping the light response. Biophysical studies of Kx channels are limited. For example, the effects of a conventional blocker of potassium channels...

journal_title：Annals of biomedical engineering

authors： Liu XD,Kourennyi DE

更新日期：2004-10-01 00:00:00

abstract：:Percutaneous stent implantation has revolutionized the clinical treatment of occluded arteries. Nevertheless, there is still a large unmet need to prevent re-occlusion after implantation. Consequently, a niche exists for a cost-effective pre-clinical method of evaluating novel interventional devices in human models. T...

journal_title：Annals of biomedical engineering

authors： Punchard MA,O'Cearbhaill ED,Mackle JN,McHugh PE,Smith TJ,Stenson-Cox C,Barron V

更新日期：2009-07-01 00:00:00

abstract：:Fox and Lu derived an algorithm based on stochastic differential equations for approximating the kinetics of ion channel gating that is simpler and faster than "exact" algorithms for simulating Markov process models of channel gating. However, the approximation may not be sufficiently accurate to predict statistics of...

journal_title：Annals of biomedical engineering

authors： Bruce IC

更新日期：2009-04-01 00:00:00

abstract：:Cochlear implantation consists in electrically stimulating the auditory nerve by inserting an electrode array inside the cochlea, a bony structure of the inner ear. In the absence of any visual feedback, the insertion results in many cases of damages of the internal structures. This paper presents a feasibility study ...

journal_title：Annals of biomedical engineering

authors： Lavenir L,Zemiti N,Akkari M,Subsol G,Venail F,Poignet P

更新日期：2020-10-30 00:00:00

abstract：:A lumped parameter compartmental model for the nonsteady flow of the cerebrovascular fluid is constructed. The model assumes constant resistances that relate fluid flux to pressure gradients, and compliances between compartments that relate fluid accumulation to rate of pressure changes. Resistances are evaluated by u...

journal_title：Annals of biomedical engineering

authors： Sorek S,Bear J,Karni Z

更新日期：1989-01-01 00:00:00

abstract：:An algorithm to track a rat swimming in a Morris Water Maze has been developed. The system is automatically configured to any pool and relative suitable light conditions. It tracks the rat's position and head pose 10 times per second. The output data is displayed in a bitmap and also in a text file. The system was tes...

journal_title：Annals of biomedical engineering

authors： Hval ES,Barrett SF,Wilcox M,Bailey TA

更新日期：2004-08-01 00:00:00

abstract：:We propose a mathematical model for analyses of the elastic properties of the wall of the outer hair cell (OHC) in the inner ear. The model reflects the properties of the major components of the OHC wall: the subsurface cisternae, the cortical lattice, the plasma membrane, and the radial pillars. The wall is treated a...

journal_title：Annals of biomedical engineering

authors： Spector AA,Brownell WE,Popel AS

更新日期：1998-01-01 00:00:00

abstract：:Gas bubble motion in a blood vessel causes temporal and spatial gradients of shear stress at the cell surface lining the vessel wall as the bubble approaches the cell, moves over it and passes it by. Rapid reversals occur in the sign of the shear stress imparted to the cell surface during this motion. These may result...

journal_title：Annals of biomedical engineering

authors： Swaminathan TN,Ayyaswamy PS,Eckmann DM

更新日期：2010-12-01 00:00:00

abstract：:This study presents a novel approach to modeling the electrocardiogram (ECG): the Gaussian pulse decomposition. Constituent waves of the ECG are decomposed into and represented by Gaussian pulses using an iterative algorithm: the chip away decomposition (ChAD) algorithm. At each iteration, a nonlinear minimization met...

journal_title：Annals of biomedical engineering

authors： Suppappola S,Sun Y,Chiaramida SA

更新日期：1997-03-01 00:00:00

abstract：:The purpose of this study is to measure the transmural pressure-cross sectional area relation of micro tubes (240 microns diameter) and to compare the measured perfusion pressure-flow relation with the pressure-flow relation calculated from the experimental pressure-cross sectional area relation. The microtubes are ma...

journal_title：Annals of biomedical engineering

authors： Sipkema P,Westerhof N

更新日期：1989-01-01 00:00:00

abstract：:In the past decades, vascular tissue engineering has made great strides towards bringing engineered vascular tissues to the clinics and, in parallel, obtaining in-lab tools for basic research. Herein, we propose the design of a novel dual-mode bioreactor, useful for the fabrication (construct mode) and in vitro stimul...

journal_title：Annals of biomedical engineering

authors： Bono N,Meghezi S,Soncini M,Piola M,Mantovani D,Fiore GB

更新日期：2017-06-01 00:00:00

abstract：:The continuing lack of longitudinal histopathological and biomechanical data for human arteries in health and disease highlights the importance of studying the many genetic, pharmacological, and surgical models that are available in mice. As a result, there has been a significant increase in the number of reports on t...

journal_title：Annals of biomedical engineering

authors： Bersi MR,Ferruzzi J,Eberth JF,Gleason RL Jr,Humphrey JD

更新日期：2014-06-01 00:00:00

abstract：:Arterial responses to diverse pathologies and insults likely occur via similar mechanisms. For example, many studies suggest that the natural process of aging and isolated systolic hypertension share many characteristics in arteries, including loss of functional elastin, decreased smooth muscle tone, and altered rates...

journal_title：Annals of biomedical engineering

authors： Valentín A,Humphrey JD,Holzapfel GA

更新日期：2011-07-01 00:00:00

abstract：:For several years, Virginia Tech and other schools have measured the frequency and severity of head impacts sustained by collegiate American football players in real time using the Head Impact Telemetry (HIT) System of helmet-mounted accelerometers. In this study, data from 37,128 head impacts collected at Virginia Te...

journal_title：Annals of biomedical engineering

authors： Funk JR,Rowson S,Daniel RW,Duma SM

更新日期：2012-01-01 00:00:00

abstract：:Studying human cancer from a biomechanical perspective may contribute to pathogenesis understanding which leads to the malignancy. In this study, biomechanics of suspended and adhered breast cancer cells were investigated via the micropipette aspiration method with special emphasis on comparing the cell stiffness and ...

journal_title：Annals of biomedical engineering

authors： Metsiou DN,Siatis KE,Giannopoulou E,Papachristou DJ,Kalofonos HP,Koutras A,Athanassiou G

更新日期：2019-08-01 00:00:00

abstract：:An endovascular technique using a stent has been developed and successfully applied in the treatment of wide neck aneurysms. A stent can facilitate thrombosis in the aneurysm pouch while maintaining biocompatible passage of the parent artery. Insertion of the stent changes the flow characteristics inside the aneurysm ...

journal_title：Annals of biomedical engineering

authors： Rhee K,Han MH,Cha SH

更新日期：2002-07-01 00:00:00

abstract：:Parameters of physiological models are commonly associated in an input-output experiment with a specific pattern of the system response. This association is often made on an intuitive basis by traditional sensitivity analysis, i.e., by inspecting the variations of model output trajectories with respect to parameter va...

journal_title：Annals of biomedical engineering

authors： Thomaseth K,Cobelli C

更新日期：1999-09-01 00:00:00