The significance of cystic hygroma in fetuses.

abstract：:Tumor necrosis factor alpha (TNF alpha) and interleukin-6 (IL-6) antigenic sites were shown within the resident glomerular mesangial cells of lupus nephritis patients applying the colloidal gold immunocytochemical approach at the electron microscopic level. Using specific polyclonal antibodies against human recombinan...

journal_title：Human pathology

authors： Malide D,Russo P,Bendayan M

更新日期：1995-05-01 00:00:00

abstract：:Recent evidence has invoked immunohistochemical expression of p63 in Merkel cell carcinoma as an adverse prognostic factor. Conflicting data led us to evaluate this. An Eastern Canadian cohort diagnosed between 1990 and 2012 was studied. Demographic and clinical data were obtained from pathology records and Provincial...

journal_title：Human pathology

authors： Fleming KE,Ly TY,Pasternak S,Godlewski M,Doucette S,Walsh NM

更新日期：2014-05-01 00:00:00

abstract：:Urethral caruncle is a benign polypoid mass of the urethral meatus in primarily postmenopausal women. Although a conclusive association with malignancy, urologic disorder, or systemic disease has not been established, often the lesion carries a challenging clinical differential diagnosis that includes malignancy. Conv...

journal_title：Human pathology

authors： Conces MR,Williamson SR,Montironi R,Lopez-Beltran A,Scarpelli M,Cheng L

更新日期：2012-09-01 00:00:00

abstract：:Paracoccidioidomycosis is a systemic mycosis with a geographic distribution that is limited to Central and South America; Brazil has the highest number of cases. Severe disseminated disease caused by paracoccidioidomycosis was observed in acquired immunodeficiency syndrome patients who live or have resided in endemic ...

journal_title：Human pathology

authors： de Freitas RS,Dantas KC,Garcia RS,Magri MM,de Andrade HF Jr

更新日期：2010-09-01 00:00:00

abstract：:We report 2 ovarian neoplasms in women aged 58 and 69 years composed of an admixture of adenosarcoma and a predominant stromal component morphologically and immunohistochemically in keeping with juvenile granulosa cell tumor. As far as we are aware, this association has not been reported previously. We speculate that,...

journal_title：Human pathology

authors： Carleton C,Houghton OP,McCluggage WG

更新日期：2015-04-01 00:00:00

abstract：:To achieve real-time connectivity between its 8 hopital-based laboratories, Veterans Integrated Service Network (VISN) 12, headquartered in Chicago, IL, has implemented a hybrid dynamic store-and-forward (HDSF) telepathology network that extends across portions of 3 states. The majority of diagnostic telepathology fun...

journal_title：Human pathology

authors： Dunn BE,Choi H,Almagro UA,Recla DL

更新日期：2001-12-01 00:00:00

abstract：:CD10 is common in B-precursor acute lymphoblastic leukemia (ALL) but is rare in acute myeloid leukemia (AML). However, until recently, analysis for CD10 has generally required fresh or frozen tissue. 56C6 is a monoclonal antibody that is now commercially available for the detection of CD10 in routinely processed paraf...

journal_title：Human pathology

authors： Bavikatty NR,Ross CW,Finn WG,Schnitzer B,Singleton TP

更新日期：2000-09-01 00:00:00

abstract：:Clusterin has been reported to play a significant role in tumorigenesis, and its overexpression occurs in various human malignancies. We examine the clusterin overexpression in human hepatocellular carcinoma (HCC) and verify its clinical usefulness as a candidate biomarker by clinicopathologic and survival analysis. W...

journal_title：Human pathology

authors： Kang YK,Hong SW,Lee H,Kim WH

更新日期：2004-11-01 00:00:00

abstract：:We have previously reported that the drs gene has the ability to suppress transformation by v-src and v-K-ras in the rat cell line F2808. We have also shown that the expression of drs mRNA is markedly reduced in a variety of human cancer cell lines, suggesting that down-regulation of drs mRNA is correlated with the de...

journal_title：Human pathology

authors： Kim CJ,Shimakage M,Kushima R,Mukaisho K,Shinka T,Okada Y,Inoue H

更新日期：2003-07-01 00:00:00

abstract：:The histogenesis of colloid cysts (CCs) of the third ventricle has been a subject of controversy. We examined, using immunohistochemical techniques, four CCs for the presence of cytokeratins (CKs), glutathione S-transferase isoenzymes (GST-pi, GST-mu), and glial fibrillary acidic protein. Antibodies to both low molecu...

journal_title：Human pathology

authors： Tsuchida T,Hruban RH,Carson BS,Phillips PC

更新日期：1992-07-01 00:00:00

abstract：:A case of clear cell sarcoma of tendons and aponeuroses arising in the elbow of a young woman is reported. Local recurrence and lymph node metastases occurred despite radiation therapy, chemotherapy, and amputation of the right arm, and the patient died of the tumor approximately ten months after the initial diagnosis...

journal_title：Human pathology

authors： Azumi N,Turner RR

更新日期：1983-12-01 00:00:00

abstract：:Pleomorphic adenoma (PA) is the most common benign tumor of salivary glands. Carcinomas in pleomorphic adenomas (CPAs) may arise by malignant transformation of the epithelial components of PAs. Occasionally, transitional zones containing cells with histological features intermediate between those of the benign PA and ...

journal_title：Human pathology

authors： Yamamoto Y,Kishimoto Y,Virmani AK,Smith A,Vuitch F,Albores-Saavedra J,Gazdar AF

更新日期：1996-08-01 00:00:00

abstract：:The surgical pathologist is often called upon to make a rapid decision about the malignant potential of a soft tissue tumor. These tumors have specific stromas that support growth and endow the tumor with unique qualities, as well as being manifestations of the phenotypic expression of tumor cells. Collagen, the major...

journal_title：Human pathology

authors： Stern R

更新日期：1981-09-01 00:00:00

abstract：:Medical culture espouses patient interaction based on detached concern, where emotional attachment to patients is attenuated to preserve objectivity. The body is viewed as nonliving matter in motion. Alternatively, the cadaver may be considered a gift. To receive so awesome a gift is an extraordinary privilege; acknow...

journal_title：Human pathology

authors： Sukol RB

更新日期：1995-07-01 00:00:00

abstract：:δ-Like ligand 4 (DLL4), a ligand for the Notch family of receptors, forecasts the prognosis of several human malignancies. However, the expression and role of DLL4 in breast cancer remain largely unknown. In the present study, we first evaluated whether the overexpression of DLL4 could be used as an indicator of axill...

journal_title：Human pathology

authors： Xiao M,Yang S,Ning X,Huang Y

更新日期：2014-11-01 00:00:00

abstract：:Twenty-six women with multiple human papillomavirus (HPV)-related lesions of the lower genital tract were investigated by immunohistochemistry for the internal genus-specific capsid antigen of HPV and by DNA-DNA in situ hybridization with 35S-radiolabeled probes for sequences of HPV-6/11, HPV-16, and HPV-18. The vulva...

journal_title：Human pathology

authors： Pilotti S,Gupta J,Stefanon B,De Palo G,Shah KV,Rilke F

更新日期：1989-02-01 00:00:00

abstract：:Preserving small pieces of frozen tissue for possible future ancillary studies ("tumor banking") usually involves either placing a small piece of tissue in a cryovial and snap freezing it in liquid nitrogen or embedding and freezing the tissue in a block of cryopreservation medium, such as optimal cutting temperature ...

journal_title：Human pathology

authors： Loken SD,Demetrick DJ

更新日期：2005-09-01 00:00:00

abstract：:A 35-year-old white Jewish homosexual man who had undergone surgery and chemotherapy for an embryonal carcinoma of the testis subsequently developed Kaposi's sarcoma. The neoplasm involved the skin as well as visceral tissues. Tissue derived from a biopsy specimen of one of the skin lesions was used in the in situ hyb...

journal_title：Human pathology

authors： Fenoglio CM,Oster MW,Lo Gerfo P,Reynolds T,Edelson R,Patterson JA,Madeiros E,McDougall JK

更新日期：1982-10-01 00:00:00

abstract：:Isolated submandibular adenopathy developed in a patient who had subacute erythroleukemia. Lymph node biopsy revealed a proliferation of immature cells and scattered foci of dyserythropoietic normoblasts. Since a review of the literature revealed no detailed description of an erythroleukemic lymph node infiltrate, a h...

journal_title：Human pathology

authors： Keifer J,Zaino R,Ballard JO

更新日期：1984-11-01 00:00:00

abstract：:Primary small bowel adenocarcinoma is rare. Although generally similar to colonic adenocarcinoma, some small bowel adenocarcinomas exhibit unique morphologic features, particularly those arising in association with Crohn disease. In this study, 15 sporadic small bowel adenocarcinomas and 11 Crohn enteritis-associated ...

journal_title：Human pathology

authors： Whitcomb E,Liu X,Xiao SY

更新日期：2014-02-01 00:00:00

abstract：:Pediatric follicular lymphoma (pFL) is a rare neoplasm with features differing from follicular lymphoma arising in adults. Here, we describe a rare case of pFL that showed morphologic features partially overlapping with progressive transformation of germinal centers and reactive follicular hyperplasia. As typical of p...

journal_title：Human pathology

authors： Karnik T,Ozawa MG,Lefterova M,Luna-Fineman S,Alvarez E,Link M,Zehnder JL,Arber DA,Ohgami RS

更新日期：2015-04-01 00:00:00

abstract：:The clinical, pathologic, and immunologic features in nine cases of non-Hodgkin's lymphoma of the multilobated B-cell type are described. Clinical and phenotypic heterogeneity was observed in these B-cell neoplasms. A probable follicular center cell derivation for these cytologically unusual B-cell lymphomas is suppor...

journal_title：Human pathology

authors： O'Hara CJ,Said JW,Pinkus GS

更新日期：1986-06-01 00:00:00

abstract：:Tissues obtained from 600 routine autopsies were studied. Mineral oil lipidosis was present in the spleen (76 per cent), liver (45 per cent), bone marrow (26 per cent), and lymph nodes; more than 50 per cent of the lymph nodes from the mesentery, porta hepatis, and mediastinum were affected. Mineral oil and its metabo...

journal_title：Human pathology

authors： Cruickshank B,Thomas MJ

更新日期：1984-08-01 00:00:00

abstract：:GATA-3 and estrogen receptor (ER) are involved in a positive cross-regulatory loop and are frequently coexpressed in breast cancers. GATA-3 expression was shown to be an independent predictor of overall and disease-free survival in some studies, whereas others showed no difference. However, the studies used different ...

journal_title：Human pathology

authors： Gulbahce HE,Sweeney C,Surowiecka M,Knapp D,Varghese L,Blair CK

更新日期：2013-11-01 00:00:00

abstract：:Three ovarian thecomas were studied by ultrastructural and immunohistochemical techniques. In each tumor, a small number of tumor cells stained for estradiol. Vacuolated as well as plump non-vacuolated tumor cells were positive, but spindle-shaped cells were negative. Ultrastructural examination showed two principle c...

journal_title：Human pathology

authors： Gaffney EF,Majmudar B,Hewan-Lowe K

更新日期：1984-02-01 00:00:00

abstract：:Primary colorectal diffuse large B-cell lymphoma (DLBCL) is rare, and its clinicopathological and genetic features are poorly understood. The aim of our study was to elucidate the frequency and prognostic significance of molecular subgroups in colorectal DLBCL. We examined 25 cases of colorectal lymphoma with DLBCL-li...

journal_title：Human pathology

authors： Hori Y,Yamamoto H,Nozaki Y,Torisu T,Fujiwara M,Taguchi K,Nishiyama K,Nakamura S,Kitazono T,Oda Y

更新日期：2020-02-01 00:00:00

abstract：:Metallothionein is a group of small molecular weight cysteine-rich proteins with a broad variety of functions. Metallothionein has been shown to regulate apoptosis and proliferation. Overexpression of metallothionein frequently occurs in human tumors and is related to prognosis as well as therapy response. However, me...

journal_title：Human pathology

authors： Schmitz KJ,Lang H,Kaiser G,Wohlschlaeger J,Sotiropoulos GC,Baba HA,Jasani B,Schmid KW

更新日期：2009-12-01 00:00:00

abstract：:Epigenetic factors contribute to carcinogenesis, tumor promotion, and chemoresistance. Histone deacetylases (HDACs) are epigenetic regulators that primarily cause chromatin compaction, leading to inaccessibility of promoter regions and eventually gene silencing. Many cancer entities feature overexpression of HDACs. Cu...

journal_title：Human pathology

authors： Klieser E,Urbas R,Stättner S,Primavesi F,Jäger T,Dinnewitzer A,Mayr C,Kiesslich T,Holzmann K,Di Fazio P,Neureiter D,Swierczynski S

更新日期：2017-07-01 00:00:00

abstract：:Four monoclonal antibodies (MoAbs), 60.15, 61.3, 105.10, and 2.16, directed to different proteins of Mycobacterium tuberculosis were used by an indirect avidin-biotin complex peroxidase-antiperoxidase method to detect mycobacterial antigens in lung, lymph node, and joint tissue specimens of tuberculous patients. Using...

journal_title：Human pathology

authors： Barbolini G,Bisetti A,Colizzi V,Damiani G,Migaldi M,Vismara D

更新日期：1989-11-01 00:00:00

abstract：:Benign lymphocytic angiitis and granulomatosis is a T-cell lymphoproliferative disorder confined to the lung and corresponding to a low-grade angiocentric immunoproliferative lesion. Controversy remains as to whether these lesions are lymphomas. We report such a case in an 8-year-old patient with Burkitt's lymphoma in...

journal_title：Human pathology

authors： Vergier B,Capron F,Trojani M,Labouyrie E,Ferrer J,Eghbali H,Merlio JP,de Mascarel A

更新日期：1992-10-01 00:00:00