Combined robotic and nonrobotic telepathology as an integral service component of a geographically dispersed laboratory network.

abstract：:Although the histopathologic patterns associated with Helicobacter pylori infection have been described, details of the interaction between bacteria, epithelial cells, and inflammatory cells remain elusive. One of the limiting factors has been the lack of a staining technique that allows the simultaneous visualization...

journal_title：Human pathology

authors： Genta RM,Robason GO,Graham DY

更新日期：1994-03-01 00:00:00

abstract：:Our aim was to investigate the expression of micro-RNA-200b (miR-200b) and cAMP-responsive element-binding protein 1 (CREB-1) in astrocytoma and its efficacy for predicting outcome. Both miR-200b and CREB-1 messenger RNA expression was measured in 122 astrocytomas and 30 nonneoplastic brain specimens by quantitative r...

journal_title：Human pathology

authors： Zhang JQ,Yao QH,Kuang YQ,Ma Y,Yang LB,Huang HD,Cheng JM,Yang T,Liu EY,Liang L,Fan KX,Zhao K,Xia X,Gu JW

更新日期：2014-10-01 00:00:00

abstract：:A 41 year old woman was treated for metrorrhagia with Ovral three times daily for one week, followed by a single daily dose for one month. Hysterectomy and bilateral salpingo-oophorectomy were performed. Histologically the mucosa of both fallopian tubes had large areas of decidual reaction underlying atrophic epitheli...

journal_title：Human pathology

authors： Mills SE,Fechner RE

更新日期：1980-09-01 00:00:00

abstract：:Fibroepithelial lesions (FEL) of the breast are notoriously difficult to classify on core needle biopsies. The goal of this study was to evaluate interobserver variability and accuracy of subclassifying difficult FELs into fibroadenoma (FA) and phyllodes tumors (PTs). We identified 50 breast core needle biopsies, init...

journal_title：Human pathology

authors： Bandyopadhyay S,Barak S,Hayek K,Thomas S,Saeed H,Beydoun R,Shi D,Arabi H,Ruterbusch J,Cote M,Ali-Fehmi R

更新日期：2016-01-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF), is an angiogenic factor that plays important roles in tumor growth. Angiogenesis studies on VEGF deal with various types of malignant tumors, but very little is known about the role or significance of VEGF in human thyroid neo...

journal_title：Human pathology

authors： Katoh R,Miyagi E,Kawaoi A,Hemmi A,Komiyama A,Oyama T,Shibuya M

更新日期：1999-08-01 00:00:00

abstract：:HMGB2 is an important protein in carcinogenesis. However, little is known about the specific role of HMGB2 in gastric cancer. In the present study, HMGB2 expression was evaluated in 198 primary gastric cancer tissues and their adjacent nontumor controls. The correlation between HMGB2 expression and clinico-pathologica...

journal_title：Human pathology

authors： Cui G,Cai F,Ding Z,Gao L

更新日期：2019-02-01 00:00:00

abstract：:Serous surface carcinoma (SSC) is a neoplasm histologically indistinguishable from typical serous carcinomas that arise from the ovary but has a distinct clinical presentation. It is characterized by widespread peritoneal dissemination at presentation, but the ovaries are grossly normal in size and shape. If the carci...

journal_title：Human pathology

authors： Quezado MM,Moskaluk CA,Bryant B,Mills SE,Merino MJ

更新日期：1999-02-01 00:00:00

abstract：:NLRC3 is a member of the nucleotide-binding domain and leucine-rich repeat (NLR) family protein that plays a role in inflammation and immunity. Although chronic inflammation has been identified as a hallmark of cancer, NLRC3 expression correlation with the development and prognosis of hepatocellular carcinoma (HCC) is...

journal_title：Human pathology

authors： Ma YY,Zhang GH,Li J,Wang SB,Hu ZM,Zhang CW,Li E

更新日期：2018-12-01 00:00:00

abstract：:Interferon-induced protein with tetratricopeptide repeat 1 (IFIT1) plays a key role in growth suppression and apoptosis promotion in cancer cells. Interferon was reported to induce the expression of IFIT1 and inhibit the expression of O-6-methylguanine-DNA methyltransferase (MGMT).This study aimed to investigate the e...

journal_title：Human pathology

authors： Zhang JF,Chen Y,Lin GS,Zhang JD,Tang WL,Huang JH,Chen JS,Wang XF,Lin ZX

更新日期：2016-06-01 00:00:00

abstract：:Acinar cell carcinoma (ACC) is a rare tumor that differentiates toward pancreatic acinar cells and shows evidence of pancreatic enzyme production. Mixed acinar-neuroendocrine carcinoma (MANC) is defined as having more than 30% of both acinar and neuroendocrine cell types as per immunohistochemistry analysis. Trypsin i...

journal_title：Human pathology

authors： Said S,Kurtin PJ,Nasr SH,Graham RP,Dasari S,Vrana JA,Yasir S,Torbenson MS,Zhang L,Mounajjed T,Eric Chen ZM,Lee HE,Wu TT

更新日期：2020-09-01 00:00:00

abstract：:Previous studies have proven that the lepidic component of lung adenocarcinoma is an independent prognostic factor and has a favorable effect on patient prognosis; however, no studies have reported the specific distribution of the lepidic component in lung cancer. In this study, we focused mainly on whether the lepidi...

journal_title：Human pathology

authors： Bian T,Jiang D,Feng J,Liu J,Qian L,Zhang Q,Li X,Liu Y,Zhang J

更新日期：2019-01-01 00:00:00

abstract：:The present report is a neuropathologic study of three patients who died from a severe form of necrotizing encephalopathy following intrathecal methotrexate therapy and craniospinal irradiation for acute lymphoblastic leukemia. During the early phase the lesion presented as multifocal coalescing areas of coagulation n...

journal_title：Human pathology

authors： Liu HM,Maurer HS,Vongsvivut S,Conway JJ

更新日期：1978-11-01 00:00:00

abstract：:Only 8 cases of hamartomas of mature cardiac myocytes have been reported. The aim of the study was to describe 7 new cases and provide clinicopathologic correlation. Our anatomical pathology database was searched for all cases of cardiac hamartoma, of which 7 represented mature myocyte type. Medical records were revie...

journal_title：Human pathology

authors： Fealey ME,Edwards WD,Miller DV,Menon SC,Dearani JA

更新日期：2008-07-01 00:00:00

abstract：:Hepatic involvement by a T-cell neoplasm is rare and often challenging to diagnose in liver biopsies. We collected 40 cases of T-cell neoplasms diagnosed in the liver from five large academic institutions to assess the clinicopathologic features. The patients included 11 women and 29 men, with a median age of 54 (rang...

journal_title：Human pathology

authors： Li P,Zhang D,Zhou J,Li P,Shen Y,Pan Z,Evans AG,Liao X

更新日期：2020-12-01 00:00:00

abstract：:A case of hemangiopericytoma arising in the esophagus is described. The light microscopic features were typical, and ultrastructural examination confirmed the presence of pericyte-like cells and excluded smooth muscle and fibroblastic differentiation. Areas of necrosis and a focus of mitotic activity within the tumor ...

journal_title：Human pathology

authors： Burke JS,Ranchod M

更新日期：1981-01-01 00:00:00

abstract：:A small number (4% to 6%) of primary malignant lymphomas arising in the intestines express the EBV genome. However, in these tumors, the viral genotype and the role of tumor suppressor gene p53 have not been investigated. We sought to determine what genotype of EBV is frequently involved and whether the expression of ...

journal_title：Human pathology

authors： Kim YS,Kim JB,Kang YK,Nam ES,Park SH,Kim I

更新日期：1999-10-01 00:00:00

abstract：:In two patients with malignant germ cell tumors angiosarcoma developed through two apparently different mechanisms. In one case the angiosarcoma probably developed as a complication of therapeutic radiation, since radiation changes were demonstrated in tissue adjacent to the neoplasm and since the angiosarcoma was not...

journal_title：Human pathology

authors： Ulbright TM,Clark SA,Einhorn LH

更新日期：1985-03-01 00:00:00

abstract：:Mucoepidermoid carcinoma of the breast is a rare entity with specific morphologic and immunohistochemical features similar to its salivary gland counterpart. In the 28 reported cases to date, there has not been a comparison of the molecular characteristics of this tumor with salivary gland mucoepidermoid carcinomas. H...

journal_title：Human pathology

authors： Camelo-Piragua SI,Habib C,Kanumuri P,Lago CE,Mason HS,Otis CN

更新日期：2009-06-01 00:00:00

abstract：:In this series of 3,432 cases of malignant melanoma of the choroid and ciliary body, mortality from metastasis 15 years after enucleation was 46 per cent. This mortality was at least ten times greater than has been observed with tumors of the iris, probably owing to the greater size and more malignant cytology of chor...

journal_title：Human pathology

authors： McLean IW,Foster WD,Zimmerman LE

更新日期：1982-02-01 00:00:00

abstract：:Merkel cell polyomavirus is of oncogenic significance in approximately 80% of Merkel cell carcinomas. Morphological subcategories of the tumor differ in regard to viral status, the rare combined type being uniformly virus negative and the predominant pure type being mainly virus positive. Indications that different bi...

journal_title：Human pathology

authors： Lai JH,Fleming KE,Ly TY,Pasternak S,Godlewski M,Doucette S,Walsh NM

更新日期：2015-09-01 00:00:00

abstract：:Glial tumors of the retina are rare. Most are syndrome associated and include pilocytic astrocytoma in neurofibromatosis type 1 and subependymal giant cell astrocytoma in tuberous sclerosis complex. Acquired, more conventional, diffuse astrocytomas are less frequent. Ependymoma is exquisitely rare. Herein, we report t...

journal_title：Human pathology

authors： Tay A,Scheithauer BW,Cameron JD,Myhre MJ,Boerner MJ

更新日期：2009-04-01 00:00:00

abstract：:Despite the nearly ubiquitous expression of telomerase in almost all types of malignant human tumors, studies have shown widely varying positivity in the highest-grade glioma, the glioblastomas (GBMs), ranging from 26% to 100% of tumors analyzed. We have previously shown significant variability in positive versus nega...

journal_title：Human pathology

authors： Kleinschmidt-Demasters BK,Evans LC,Bobak JB,Lopez-Uribe D,Hopper D,Shroyer AL,Shroyer KR

更新日期：2000-08-01 00:00:00

abstract：:Prostate-specific membrane antigen (PSMA), a type II transmembrane metallo-peptidase highly overexpressed in prostate cancer cells, has been studied as a targeting molecule in prostate cancer. Recently, PSMA has also been found to be expressed in the neovasculature of multiple nonprostatic solid tumors. Because of its...

journal_title：Human pathology

authors： Haffner MC,Kronberger IE,Ross JS,Sheehan CE,Zitt M,Mühlmann G,Ofner D,Zelger B,Ensinger C,Yang XJ,Geley S,Margreiter R,Bander NH

更新日期：2009-12-01 00:00:00

abstract：:Four monoclonal antibodies (MoAbs), 60.15, 61.3, 105.10, and 2.16, directed to different proteins of Mycobacterium tuberculosis were used by an indirect avidin-biotin complex peroxidase-antiperoxidase method to detect mycobacterial antigens in lung, lymph node, and joint tissue specimens of tuberculous patients. Using...

journal_title：Human pathology

authors： Barbolini G,Bisetti A,Colizzi V,Damiani G,Migaldi M,Vismara D

更新日期：1989-11-01 00:00:00

abstract：:Clear cell sarcoma is a rare and malignant soft tissue tumor that shows phenotypic and immunohistochemical overlap with cutaneous malignant melanoma; identification of biomarkers that differentiate clear cell sarcoma from malignant melanoma is therefore needed. In this study, we performed mutation analysis of BRAF and...

journal_title：Human pathology

authors： Yang L,Chen Y,Cui T,Knösel T,Zhang Q,Geier C,Katenkamp D,Petersen I

更新日期：2012-09-01 00:00:00

abstract：:ATP-binding cassette (ABC) multidrug transporters have been associated with chemoresistance, which is a major obstacle in attempts to improve clinical outcome of patients with nasopharyngeal carcinoma (NPC). In this study, we investigated 3 ABC multidrug transporters including MDR1, MRP1, and BCRP for their potential ...

journal_title：Human pathology

authors： Larbcharoensub N,Leopairat J,Sirachainan E,Narkwong L,Bhongmakapat T,Rasmeepaisarn K,Janvilisri T

更新日期：2008-06-01 00:00:00

abstract：:To elucidate the pathogenesis of aging changes and their relation to age associated calcification, a morphological study of 27 human aortic valves was carried out. Nine valves were obtained from immediate autopsies and 18 valves from routine autopsies done within four hours after death. Calcium deposition was present ...

journal_title：Human pathology

authors： Kim KM,Valigorsky JM,Mergner WJ,Jones RT,Pendergrass RF,Trump BF

更新日期：1976-01-01 00:00:00

abstract：:Granulocyte alloantibodies and autoantibodies have a key role in the pathophysiology of several clinical problems. These include febrile transfusion reactions, severe pulmonary reactions to transfusion, isoimmune neonatal neutropenia, failure of effective granulocyte transfusion, autoimmune neutropenia, drug-induced n...

journal_title：Human pathology

authors： McCullough J

更新日期：1983-03-01 00:00:00

abstract：:We report here an exceptional pattern of atypical lentiginous melanocytic proliferation within an adenoma, leading to focal lamina propria infiltration and pulmonary metastasis, which was considered as primary colonic mucosal melanoma (MM) in a Caucasian patient. Such case illustrates the diagnosis criteria required t...

journal_title：Human pathology

authors： Furudoï A,Caumont C,Dutriaux C,Cappellen D,Goussot JF,Vergier B,Merlio C,Barberis C,Merlio JP,Gros A

更新日期：2016-02-01 00:00:00

abstract：:Three of eight female patients with cytomegalovirus disease had evidence of ovarian infection at autopsy. All three patients with ovarian lesions were postmenopausal; the remaining five were premenopausal. The lesions, which may be bilateral and may occur without evidence of cytomegalovirus infection elsewhere, are di...

journal_title：Human pathology

authors： Subietas A,Deppisch LM,Astarloa J

更新日期：1977-05-01 00:00:00