Prognostic value of coexistence of abnormal expression of micro-RNA-200b and cyclic adenosine monophosphate-responsive element-binding protein 1 in human astrocytoma.

abstract：:GATA3 immunostaining is a sensitive marker for mammary and urothelial carcinomas. It is routinely used in surgical pathology during workup of carcinomas of unknown origin. To the best of our knowledge, this is the first focused study of GATA3 expression in gallbladder adenocarcinomas. In this study, we evaluated GATA3...

journal_title：Human pathology

authors： Guo W,Lee W,Lu Y,Li X,Chandan VS

更新日期：2020-12-01 00:00:00

abstract：:Seminoma and sarcoidosis do not seem to be associated diseases, judging from epidemiologic data. The presence of these two diseases in the patient whose case is reported may have been coincidental. It was observed, however, that when the testis tumor appeared in this patient, the longstanding sarcoid lesions significa...

journal_title：Human pathology

authors： Colebunders R,Bultinck J,Servais J,Denis L

更新日期：1984-04-01 00:00:00

abstract：:Head and neck squamous cell carcinoma (HNSCC) typically affects male smokers older than 55 years. Recently, an increase in the incidence of HNSCC in young adults has been recognized, many of them nonsmokers and females. Functional inactivation of p16 is known to be a common event in HNSCC, mainly by either deletion or...

journal_title：Human pathology

authors： O'Regan EM,Toner ME,Finn SP,Fan CY,Ring M,Hagmar B,Timon C,Smyth P,Cahill S,Flavin R,Sheils OM,O'Leary JJ

更新日期：2008-03-01 00:00:00

abstract：:The number of opportunistic infections in the central nervous system (CNS) has been steadily increasing because of a rising number of immunocompromised patients. A rare form of CNS infection can be caused by Chaetomium species, one of the largest genera of saprophytic ascomycetes. The CNS lesions in the present case w...

journal_title：Human pathology

authors： Thomas C,Mileusnic D,Carey RB,Kampert M,Anderson D

更新日期：1999-07-01 00:00:00

abstract：:A century or so ago, pediatrics and pediatric pathology did not exist. Then, many fetuses/newborns died in utero or shortly after birth. With time, the issue of sepsis was addressed, and a greater number of newborns survived. Gradually, in this soil, the disciplines of pediatrics and pediatric nursing arose, as some r...

journal_title：Human pathology

authors： Nezelof C,Seemayer TA,Bridge JA

更新日期：2010-03-01 00:00:00

abstract：:We examined the infection of herpes simplex virus (HSV), human cytomegalovirus (HCMV), and Epstein-Barr virus (EBV) in 61 autopsy cases with secondary diffuse interstitial pneumonia (SDIP) by immunohistochemistry and compared our findings with those in 46 individuals without lung complications. There was no significan...

journal_title：Human pathology

authors： Oda Y,Okada Y,Katsuda S,Nakanishi I

更新日期：1994-10-01 00:00:00

abstract：:We received the clinical records and pathologic material of 20 patients with biopsy proven hepatic focal nodular hyperplasia. The majority of the patients were females of child bearing age, five of whom had a history of oral use of contraceptives. In every instance focal nodular hyperplasia was an incidental finding; ...

journal_title：Human pathology

authors： Knowles DM,Wolff M

更新日期：1976-09-01 00:00:00

abstract：:We have previously reported that the drs gene has the ability to suppress transformation by v-src and v-K-ras in the rat cell line F2808. We have also shown that the expression of drs mRNA is markedly reduced in a variety of human cancer cell lines, suggesting that down-regulation of drs mRNA is correlated with the de...

journal_title：Human pathology

authors： Kim CJ,Shimakage M,Kushima R,Mukaisho K,Shinka T,Okada Y,Inoue H

更新日期：2003-07-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is a group of granulomatous disorders in which abnormal Langerhans cells proliferate as either a localized lesion in a single bone or disseminated disease involving two or more organs or systems. Because the different LCH forms exhibit significantly elevated levels of inflammatory m...

journal_title：Human pathology

authors： Murakami I,Matsushita M,Iwasaki T,Kuwamoto S,Kato M,Horie Y,Hayashi K,Imamura T,Morimoto A,Imashuku S,Gogusev J,Jaubert F,Takata K,Oka T,Yoshino T

更新日期：2014-01-01 00:00:00

abstract：:To better represent the Gleason score of radical prostatectomy, the International Society of Urologic Pathologists Consensus Committee recommends assigning individual Gleason scores to prostate cancer cores submitted in separate containers and/or multiple cores in the same container with site identifiers. However, sce...

journal_title：Human pathology

authors： Kunju LP,Daignault S,Wei JT,Shah RB

更新日期：2009-04-01 00:00:00

abstract：:Thirty cases of ductal carcinoma in situ (DCIS) of the breast, showing histological microcalcifications, were studied to clarify their mechanism of formation. Undecalcified sections revealed three types of calcium precipitates: type I and II granular calcifications (GCs) and laminar calcifications (LCs). In type I GCs...

journal_title：Human pathology

authors： Foschini MP,Fornelli A,Peterse JL,Mignani S,Eusebi V

更新日期：1996-02-01 00:00:00

abstract：:Langerhans' cell histiocytosis (LCH) is a proliferative histiocytic disorder of unknown etiology. We previously reported that Epstein-Barr virus (EBV) infects and proliferates in macrophages, and investigated the possibility that EBV exhibits etiologic effects in LCH. To detect EBV expression, paraffin sections from 1...

journal_title：Human pathology

authors： Shimakage M,Sasagawa T,Kimura M,Shimakage T,Seto S,Kodama K,Sakamoto H

更新日期：2004-07-01 00:00:00

abstract：:Focal adhesion kinase (FAK) is one of the central signaling molecules found at focal adhesion sites, which are specific areas on the cell membrane where cells attach to extracellular matrix proteins. Focal adhesion kinase interacts with multiple signaling and adaptor molecules and effects several signaling pathways. O...

journal_title：Human pathology

authors： Madan R,Smolkin MB,Cocker R,Fayyad R,Oktay MH

更新日期：2006-01-01 00:00:00

abstract：:Epithelial-mesenchymal transition (EMT) plays a pivotal role in tumor invasion and metastasis in various malignancies. ZEB2/SIP1 is an important EMT regulator and down-regulates E-cadherin expression. The present study was planned to explore status of EMT-associated markers ZEB2/SIP1 and E-cadherin in eyelid sebaceous...

journal_title：Human pathology

authors： Bhardwaj M,Sen S,Sharma A,Kashyap S,Chosdol K,Pushker N,Bajaj MS,Bakhshi S

更新日期：2015-10-01 00:00:00

abstract：:This article briefly describes the origin of one of the more common (food-related) pathologic terms--"bread and butter pericarditis." The eminent French physician, Laennec, the inventor of the stethoscope amongst several other important medical contributions, can be credited for having coined the term that is still in...

journal_title：Human pathology

authors： Cohen MB

更新日期：2004-02-01 00:00:00

abstract：:Nuclear pore complexes (NPCs) are elaborate macromolecular structures that regulate the bidirectional nucleocytoplasmic traffic system. In vertebrate cells, NPCs include a family of 50 to 100 proteins termed nucleoporins (Nups). The 88-kD Nup has been found to be linked in a dynamic subcomplex with the oncogenic CAN/N...

journal_title：Human pathology

authors： Gould VE,Orucevic A,Zentgraf H,Gattuso P,Martinez N,Alonso A

更新日期：2002-05-01 00:00:00

abstract：:Papillary carcinoma of the breast is a variant of predominantly intraductal carcinoma characterized by a papillary growth pattern with fibrovascular support. Loss of heterozygosity (LOH) was evaluated at multiple chromosomal loci (including loci reported to show frequent genetic alterations in breast cancer) to determ...

journal_title：Human pathology

authors： Lininger RA,Park WS,Man YG,Pham T,MacGrogan G,Zhuang Z,Tavassoli FA

更新日期：1998-10-01 00:00:00

abstract：:Clear cell sarcoma is a rare and malignant soft tissue tumor that shows phenotypic and immunohistochemical overlap with cutaneous malignant melanoma; identification of biomarkers that differentiate clear cell sarcoma from malignant melanoma is therefore needed. In this study, we performed mutation analysis of BRAF and...

journal_title：Human pathology

authors： Yang L,Chen Y,Cui T,Knösel T,Zhang Q,Geier C,Katenkamp D,Petersen I

更新日期：2012-09-01 00:00:00

abstract：:We report 13 cases of unique polypoid urothelial tumors with inverted growth pattern (PUTIPs) occurring in the proximal ureter and renal pelvis. We describe their morphologic features and further characterize them in regard to TERT promoter mutation status and microsatellite instability. Thirteen cases were identified...

journal_title：Human pathology

authors： Wobker SE,Zhong M,Epstein JI

更新日期：2017-01-01 00:00:00

abstract：:Two hundred three testicular germ cell tumors were studied immunohistochemically for the presence of placental alkaline phosphatase (PLAP). Special emphasis was placed on the pattern and incidence of positive staining of intratubular malignant germ cells (ITMGCs) adjacent to tumors. 99% of cases with adjacent ITMGCs s...

journal_title：Human pathology

authors： Burke AP,Mostofi FK

更新日期：1988-06-01 00:00:00

abstract：:The vascular endothelial growth factor (VEGF) family and its receptors have multifunctional activities besides angiogenesis, and some of these molecules are induced by hypoxia/ischemia. They are known to be expressed in human placenta, but little is known about their involvement in pathologic conditions. We have inves...

journal_title：Human pathology

authors： Kumazaki K,Nakayama M,Suehara N,Wada Y

更新日期：2002-11-01 00:00:00

abstract：:Giant cell tumors (GCTs) of the bone are primary skeletal neoplasms that behave intermediately between a true benign and an overtly malignant neoplasm. For two decades, controversial reports have found estrogen receptor (ER) expression in isolated cells or small numbers of samples from these tumors. In this report, we...

journal_title：Human pathology

authors： Olivera P,Perez E,Ortega A,Terual R,Gomes C,Moreno LF,Dueñas A,De La Garza J,Melendez-Zajgla J,Maldonado V

更新日期：2002-02-01 00:00:00

abstract：:The peroxidase-antiperoxidase immunohistochemical technique was employed to stain formalin fixed, paraffin embedded tissue sections from three cases of encephalitis caused by Toxoplasma gondii. We studied two cases of congenital infection and one case of acquired toxoplasmosis occurring in an immunocompromised host. T...

journal_title：Human pathology

authors： Conley FK,Jenkins KA,Remington JS

更新日期：1981-08-01 00:00:00

abstract：:Demonstration of identical allelic loss on chromosome 11q13 in synchronous in situ (DCIS) and invasive ductal (IDC) breast carcinoma has provided molecular evidence of the progression of DCIS to IDC. We investigated loss of heterozygosity (LOH) at chromosome 11q13 in the spectrum of "marker/premalignant" and "malignan...

journal_title：Human pathology

authors： Nayar R,Zhuang Z,Merino MJ,Silverberg SG

更新日期：1997-03-01 00:00:00

abstract：:T-lymphocyte subsets in peripheral blood, bronchoalveolar lavage fluid, and prescalenic lymph nodes from eight patients with sarcoidosis were evaluated with monoclonal antibodies. Both in lung and lymph nodes significant increases in helper T cells were demonstrated, except in patients with stage III pulmonary disease...

journal_title：Human pathology

authors： Viale G,Codecasa L,Bulgheroni P,Giobbi A,Madonini E,Dell'Orto P,Coggi G

更新日期：1986-05-01 00:00:00

abstract：:Intrasinusoidal infiltration of bone marrow (BM) may accompany several malignant lymphoproliferative disorders. In small B-cell lymphomas, this pattern is considered specific for splenic marginal zone lymphoma (SMZL) when exclusive or prominent, although it may occur in other subtypes of non-Hodgkin's lymphomas (NHLs)...

journal_title：Human pathology

authors： Schenka AA,Gascoyne RD,Duchayne E,Delsol G,Brousset P

更新日期：2003-08-01 00:00:00

abstract：:Clinicopathological studies of 181 patients with liver cirrhosis undergoing autopsy in the pathology department of a municipal hospital between 1973 and 1976 are reported. The main etiological types were alcoholic (25.4 per cent), HBsAg positive (14.9 per cent), and cryptogenic cirrhosis (54.7 per cent). Four patients...

journal_title：Human pathology

authors： Bartók I,Remenár,Tóth J,Duschanek P,Kanyár B

更新日期：1981-09-01 00:00:00

abstract：:Breast cancer is one of the common malignant diseases among women in Japan as well as in western countries, and its incidence continues to increase. Normal mammary duct epithelial cells exhibit a well-organized apicobasal polarity, which forms the basis for their specific structure and function. Although the loss of e...

journal_title：Human pathology

authors： Kojima Y,Akimoto K,Nagashima Y,Ishiguro H,Shirai S,Chishima T,Ichikawa Y,Ishikawa T,Sasaki T,Kubota Y,Inayama Y,Aoki I,Ohno S,Shimada H

更新日期：2008-06-01 00:00:00

abstract：:Sneddon's syndrome is a potentially fatal arterio-occlusive disorder characterized by generalized livedo racemosa and cerebrovascular lesions. Skin biopsies often fail to yield diagnostic arterial lesions. In the present series, affected vessels were found in skin biopsies from 12 of 15 patients with Sneddon's syndrom...

journal_title：Human pathology

authors： Zelger B,Sepp N,Schmid KW,Hintner H,Klein G,Fritsch PO

更新日期：1992-06-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) infection is usually reported in immunocompromised patients. This study reports 11 cases of HCMV infection of the gastrointestinal (GI) tract diagnosed in apparently immunocompetent hosts. The median age of the patients studied was 76 years, and the major presenting symptoms were diarrhea,...

journal_title：Human pathology

authors： Maiorana A,Baccarini P,Foroni M,Bellini N,Giusti F

更新日期：2003-12-01 00:00:00