Abstract:
:Tissues obtained from 600 routine autopsies were studied. Mineral oil lipidosis was present in the spleen (76 per cent), liver (45 per cent), bone marrow (26 per cent), and lymph nodes; more than 50 per cent of the lymph nodes from the mesentery, porta hepatis, and mediastinum were affected. Mineral oil and its metabolic products produce a nonfibrogenic reaction in these tissues. The differential diagnosis of mineral oil lipidosis in lymph nodes with reaction to radiopaque oils and Whipple's disease is discussed. The presence of mineral oil in para-aortic (42 per cent) and internal iliac (15 per cent) lymph nodes could result in false-positive readings after lymphangiography.
journal_name
Hum Patholjournal_title
Human pathologyauthors
Cruickshank B,Thomas MJdoi
10.1016/s0046-8177(84)80163-xsubject
Has Abstractpub_date
1984-08-01 00:00:00pages
731-7issue
8eissn
0046-8177issn
1532-8392pii
S0046-8177(84)80163-Xjournal_volume
15pub_type
杂志文章相关文献
HUMAN PATHOLOGY文献大全abstract::(90)Yttrium (Therasphere) microspheres administered via hepatic artery are a valuable option for treatment of hepatocellular carcinoma. This therapy targets tumor nodules while largely sparing hepatic parenchyma. This retrospective study examines liver explants from 13 adult patients with hepatocellular carcinoma who ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2008.06.024
更新日期:2009-01-01 00:00:00
abstract::Atypical fibro-osseous lesions, usually in the proximal femur, are a common consultative diagnostic problem. This is due to the fact that they contain a variety of patterns individually reminiscent of fibrous dysplasia, fibroxanthoma (non-ossifying fibroma), myxofibroma, lipoma, cyst, bone infarct, Paget's disease, an...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(93)90162-a
更新日期:1993-05-01 00:00:00
abstract::Among 236 aortic valves surgically excised at the Mayo Clinic in 1990 (mean patient age, 66 years; age range, 10 to 92 years), 154 (65%) were stenotic, 58 (25%) were insufficient, and 24 (10%) were both stenotic and insufficient. Pure stenosis was related to calcification, and causes included degenerative (51%), bicus...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(93)90267-k
更新日期:1993-12-01 00:00:00
abstract::Small-sized lung adenocarcinomas often contain a lepidic growth component in part. The term lepidic growth has recently been used to represent a growth pattern of neoplastic cells along preexisting alveolar structures. We reviewed 91 small-sized (≤3 cm) invasive lung adenocarcinomas with a lepidic component to study t...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2013.02.008
更新日期:2013-09-01 00:00:00
abstract::Overexpression of mitotic arrest deficient 2 (MAD2) and/or cell division cycle 20 (CDC20) in the spindle assembly checkpoint leads to chromosomal instability and aneuploidy. Cell-in-cell (CIC) structures are formed by the process where cancer or immune cells are internalized into adjacent host cancer cells. Here, we i...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2018.10.029
更新日期:2019-03-01 00:00:00
abstract::δ-Like ligand 4 (DLL4), a ligand for the Notch family of receptors, forecasts the prognosis of several human malignancies. However, the expression and role of DLL4 in breast cancer remain largely unknown. In the present study, we first evaluated whether the overexpression of DLL4 could be used as an indicator of axill...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2014.04.025
更新日期:2014-11-01 00:00:00
abstract::AT-rich interactive domain 1A (ARID1A) is tumor suppressor gene that interacts with BRG1 adenosine triphosphatase to form a SWI/SNF chromatin remodeling protein complex. Inactivation of ARID1A has been described in several neoplasms, including epithelial ovarian and endometrial carcinomas, and has been correlated with...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2014.07.003
更新日期:2014-11-01 00:00:00
abstract::Rhabdomyomas are rare tumors that usually arise within the heart, orocervical, or vulvovaginal regions. The cardiac tumors have a characteristic immature morphology, occur often in association with tuberous sclerosis, and are regarded as hamartomas rather than true neoplasms. The histogenesis of the extracardiac tumor...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(89)90050-6
更新日期:1989-04-01 00:00:00
abstract::Invasive squamous cell carcinoma (SCC) of the cervix involves the progression of premalignant cervical intraepithelial neoplasia (CIN) and is associated with persistent human papillomavirus infection. Most CINs will regress, and the challenge is to identify the lesions likely to progress to invasive cancer. We evaluat...
journal_title:Human pathology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.humpath.2016.09.019
更新日期:2017-01-01 00:00:00
abstract::Encapsulated thyroid tumors of follicular cell origin with high-grade features (EFHG) are unusual neoplasms. In current classification schemes, they are called atypical adenomas or follicular, papillary, or poorly differentiated carcinoma. When noninvasive, EFHG create a major therapeutic/diagnostic dilemma stemming f...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2009.08.011
更新日期:2010-02-01 00:00:00
abstract::RBM (RNA-binding motif) protein is a marker of male germ cells. This protein is encoded by the Azoospermia factor region-b (AZF-b) of the human Y chromosome and is expressed exclusively in the male germ cell line, that is, spermatogonia, spermatocytes, and round spermatids. The authors analyzed the expression of the R...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1053/hupa.2000.16671
更新日期:2000-09-01 00:00:00
abstract::Atypical alveolar hyperplasia (AAH) is a potential precursor lesion from which lung adenocarcinomas arise and may be a good target for studying the early events of lung tumorigenesis. We have previously shown that AAHs are neoplastic epithelial proliferations that often harbor activating mutations of the K-ras oncogen...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(98)90448-8
更新日期:1998-08-01 00:00:00
abstract::Previously used only as a screening tool, cytology now emerges as a powerful diagnostic technique, especially since the advent of the fine needle aspiration (FNA) biopsy. This article highlights the use of ancillary techniques, primarily electron microscopy (EM), and immunohistochemistry (IHC). When coupled with routi...
journal_title:Human pathology
pub_type: 杂志文章,评审
doi:10.1016/s0046-8177(98)90003-x
更新日期:1998-12-01 00:00:00
abstract::The evolution of sequential histological changes from normal cells through invasive cancer affords the cancer biologist the opportunity to identify separate molecular steps involved in cancer progression. As one studies the development of human carcinoma, it becomes apparent that multiple genetic alterations affecting...
journal_title:Human pathology
pub_type: 杂志文章,评审
doi:10.1016/0046-8177(94)90056-6
更新日期:1994-10-01 00:00:00
abstract::Fibrillar proteins with a role in cellular shape and motility are present in the cytoplasm of most animal cells. They vary greatly in size, organization, and reactivity according to cell type and can be separately identified by the use of recently developed monospecific antisera and indirect immunofluorescence stainin...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80026-3
更新日期:1981-05-01 00:00:00
abstract::Botryomycosis is a rare bacterial infection of the skin and, rarely, viscera that is characterized by the formation of characteristic hyaline grains. We encountered a patient with Erysipelothrix rhusiopathiae endocarditis who developed visceral botryomycosis. He was a 54-year-old black man who presented in sepsis with...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2004.10.004
更新日期:2005-01-01 00:00:00
abstract::The differential diagnosis of glandular lesions of the bladder/urinary tract can be challenging because of significant morphologic and immunohistochemical overlap between primary lesions and metastasis/direct extension from adjacent organs. Special AT-rich sequence-binding protein 2 (SATB2), encoded on chromosome 2q32...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2017.07.002
更新日期:2017-09-01 00:00:00
abstract::In retinoblastoma, genetic alteration of N-myc amplification different from the alteration of the RB1 gene on chromosome 13q14 has been described. This study is to determine the frequency of N-myc amplification by fluorescence in situ hybridization method in retinoblastoma. This study was prospectively derived from 26...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2007.12.008
更新日期:2008-08-01 00:00:00
abstract::Preserving small pieces of frozen tissue for possible future ancillary studies ("tumor banking") usually involves either placing a small piece of tissue in a cryovial and snap freezing it in liquid nitrogen or embedding and freezing the tissue in a block of cryopreservation medium, such as optimal cutting temperature ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2005.06.016
更新日期:2005-09-01 00:00:00
abstract::Cytochrome P-450 specific for steroid 17 alpha-hydroxylation (P-45017 alpha) was immunolocalized in normal and hyperfunctioning adrenal glands of pigs, bovines, and humans, using a specific IgG fraction raised against the enzyme. P-45017 alpha was present in the zona fasciculata (ZF) and zona reticularis (ZR), but not...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(89)90174-3
更新日期:1989-02-01 00:00:00
abstract::Patients undergoing treatment of acute lymphoblastic leukemia are at risk for fungal infections including disseminated candidiasis. We describe a case of systemic Candida albicans infection associated with life-threatening gastrointestinal hemorrhage due to unusual necrotizing vasculitis involving the gastrointestinal...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2009.09.015
更新日期:2010-04-01 00:00:00
abstract::Neutrophilic dermatoses are an uncommon manifestation of lupus. We describe the clinical and histopathologic features of 14 patients with systemic lupus erythematosus (SLE) and neutrophilic dermatoses, 2 of whom had no prior history of SLE. Thirteen patients were female, ranging in age from 27 to 62 years (mean age, 4...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2013.10.029
更新日期:2014-03-01 00:00:00
abstract::Implementation of Grade Groups (GrGrs) has been widely accepted for reporting prostate cancer grade since the 2014 International Society of Urological Pathology consensus meeting. Despite their undisputed value for risk stratification, some GrGr are, a priori, quite heterogeneous in that they contain multiple Gleason ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2020.03.001
更新日期:2020-05-01 00:00:00
abstract::Although the term "thyroiditis" suggests inflammation, many disorders of the thyroid that are of unknown etiology are also currently included under this heading. Thus, only infective thyroiditis and subacute thyroiditis are clearly inflammatory; autoimmune thyroiditis is a result of lymphocytic and fibroblastic infilt...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(78)80028-8
更新日期:1978-07-01 00:00:00
abstract::Perineural invasion is a histologic feature usually diagnostic of invasion in malignancies. In the breast, however, it has been associated with benign lesions such as sclerosing adenosis (SA), complex sclerosing lesion/radial scar (CSL/RS), and ductal carcinoma in situ (DCIS). This article describes perineural invasio...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1053/hupa.2001.27637
更新日期:2001-08-01 00:00:00
abstract::We have previously shown that necrotic tumors retain their immunoreactivity for a range of cytokeratin antibodies. Some thyroid tumors undergo extensive necrosis after fine-needle aspiration (FNA) procedures. We evaluated the sensitivity of antibodies on necrotic thyroid tumors by examining a series of thyroid tumors ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(99)90071-0
更新日期:1999-11-01 00:00:00
abstract::Hepatic artery thrombosis (HAT) following orthotopic liver transplantation (OLT) can cause hepatic parenchymal necrosis and ischemic cholangiopathy. This study investigates additional histologic features that may suggest HAT in post-OLT liver specimens. For 94 liver specimens (explanted allografts and biopsies) from p...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2019.04.019
更新日期:2019-08-01 00:00:00
abstract::The aim of this study on a series of biopsies diagnosed as normal, metaplastic, low-grade squamous intraepithelial lesions (LSILs), and high-grade squamous intraepithelial lesions (HSILs) was dual: to determine the chronology of cell cycle and proliferation abnormalities after human papillomavirus infection during the...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2005.07.016
更新日期:2005-10-01 00:00:00
abstract::This study investigate the expression of the mitogen-activated protein kinases (MAPKs) in normal prostate, benign prostatic hyperplasia (BPH), and prostatic cancer (PC), and also the possible relationship between the activity of these MAPKs and the apoptosis/proliferation index. Immunochemical techniques were carried ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1053/hupa.2002.32227
更新日期:2002-03-01 00:00:00
abstract::In this review we summarize recent advances in the histopathological diagnostic criteria and molecular pathology of the main subtypes of ovarian surface epithelial carcinoma. These advances have greatly improved our understanding of the biology of ovarian carcinoma and are also relevant to patient management. With pro...
journal_title:Human pathology
pub_type: 杂志文章,评审
doi:10.1016/j.humpath.2009.04.017
更新日期:2009-09-01 00:00:00