Abstract:
:Rhabdomyomas are rare tumors that usually arise within the heart, orocervical, or vulvovaginal regions. The cardiac tumors have a characteristic immature morphology, occur often in association with tuberous sclerosis, and are regarded as hamartomas rather than true neoplasms. The histogenesis of the extracardiac tumors and their true neoplastic nature are matters of controversy. We report the first case of a rhabdomyoma located inside the cranium. The intimate association with the mandibular division of the trigeminal nerve, the normal embryogenesis of the craniofacial muscles, and animal homograft and xenograft experiments provide a framework for considering this tumor, and possibly other rhabdomyomas, as a choristoma/hamartoma rather than a true neoplasm.
journal_name
Hum Patholjournal_title
Human pathologyauthors
Zwick DL,Livingston K,Clapp L,Kosnik E,Yates Adoi
10.1016/0046-8177(89)90050-6subject
Has Abstractpub_date
1989-04-01 00:00:00pages
390-2issue
4eissn
0046-8177issn
1532-8392pii
0046-8177(89)90050-6journal_volume
20pub_type
杂志文章相关文献
HUMAN PATHOLOGY文献大全abstract::Malignant gastrointestinal neuroectodermal tumor (MGNET) is a very rare, aggressive malignant neoplasm that may occur in any location in the gastrointestinal tract. Malignant gastrointestinal neuroectodermal tumors typically consist of sheet-like to pseudopapillary proliferation of primitive-appearing epithelioid cell...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2016.05.026
更新日期:2016-11-01 00:00:00
abstract::Proliferative lesions of breast duct epithelium are associated with an increased risk of subsequent carcinoma. Fine-needle aspiration criteria for these lesions are poorly defined; most studies are retrospective and do not clearly use the classification of Page and Rogers. Suggested criteria for "atypia" include crowd...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(93)90243-a
更新日期:1993-06-01 00:00:00
abstract::Four surgically resected cardiac valves received from three female patients showed the presence of acute and chronic rheumatic valvulitis. The material was studied by means of transmission and scanning electron microscopy. This is the first time that there has been an investigation of the ultrastructure in acute rheum...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(80)80109-2
更新日期:1980-01-01 00:00:00
abstract::Recent evidence has invoked immunohistochemical expression of p63 in Merkel cell carcinoma as an adverse prognostic factor. Conflicting data led us to evaluate this. An Eastern Canadian cohort diagnosed between 1990 and 2012 was studied. Demographic and clinical data were obtained from pathology records and Provincial...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2013.12.008
更新日期:2014-05-01 00:00:00
abstract::Glypican 3 is a heparin sulfate proteoglycan bound to the cell surface that is theorized to participate in cell signaling, resulting in embryonic cell growth and differentiation. The GPC3 gene is mutated in Simpson-Golabi-Behmel syndrome, whose features include numerous developmental abnormalities, tissue overgrowth, ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2007.06.006
更新日期:2008-02-01 00:00:00
abstract::The distinction between Spitz nevus and melanoma is currently possible, applying a set of definite histological criteria. However, in certain lesions deviating from the stereotypical morphology of classic Spitz nevi ("atypical Spitz tumors"), the differentiation between benign and malignant cases appears problematic b...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2006.02.001
更新日期:2006-07-01 00:00:00
abstract::A case of apocrine carcinoma of the breast with psammoma bodies is described in a 69 year old man. The report emphasizes the rarity of this lesion and supports currently held beliefs about the formation of psammoma bodies. ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80178-5
更新日期:1981-08-01 00:00:00
abstract::p16INK4a immunohistochemistry (IHC) is widely used to facilitate the diagnosis of human papillomavirus (HPV)-associated cervical precancerous lesions. Although most p16 results are distinctly positive or negative, certain ones are ambiguous: they meet some but not all requirements for the "block-positive" pattern. It ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2017.06.014
更新日期:2017-08-01 00:00:00
abstract::Mucin core proteins (MUCs) are expressed in tissue-specific patterns in the gastrointestinal tract and expression is deregulated in Barrett's metaplasia. Based on differential expression, MUCs have been used to classify adenocarcinomas into distinct phenotypes (eg, intestinal, gastric, pancreaticobiliary, etc). Becaus...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2013.10.020
更新日期:2014-03-01 00:00:00
abstract::Micropapillary carcinoma of the breast is associated with increased rates of lymph node metastasis and lymphovascular invasion. While activating point mutations in PIK3CA (encoding phosphatidylinositol-3-kinase catalytic subunit) or AKT1 are found in 25% to 30% of invasive ductal carcinomas, the mutational profile of ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2012.10.018
更新日期:2013-07-01 00:00:00
abstract::We examined the infection of herpes simplex virus (HSV), human cytomegalovirus (HCMV), and Epstein-Barr virus (EBV) in 61 autopsy cases with secondary diffuse interstitial pneumonia (SDIP) by immunohistochemistry and compared our findings with those in 46 individuals without lung complications. There was no significan...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(94)90065-5
更新日期:1994-10-01 00:00:00
abstract::After endoscopic resection of early gastric cancer (EGC), it is imperative to accurately determine whether follow-up surgery is indicated, since this technique is used as a first line of treatment. Herein, we developed a scoring system to indicate the risk of lymph node metastasis in submucosal EGC (smEGC), and presen...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2013.07.037
更新日期:2013-12-01 00:00:00
abstract::Loss or reduced expression of E-cadherin has been shown to be associated with poor survival in patients with bladder cancer. In numerous cases, loss of E-cadherin expression in bladder tumors has been accompanied by continued association of catenins with the membrane, suggestive of the expression of an alternative cad...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1053/hupa.2001.21140
更新日期:2001-01-01 00:00:00
abstract::This article presents a view of lymphoid tissue architecture as defined by the traffic of defined lymphoid cell classes. The compartmentalization of lymphocytes is discussed in reference to specific cell-cell interactions that occur in antigen-driven immune responses. Finally, the distribution of normal and neoplastic...
journal_title:Human pathology
pub_type: 杂志文章,评审
doi:10.1016/s0046-8177(78)80005-7
更新日期:1978-01-01 00:00:00
abstract::Parakeratosis refers to incomplete maturation of epidermal keratinocytes, resulting in abnormal retention of nuclei in the stratum corneum. It occurs in many diseases of the skin, particularly in psoriasis. Down-regulation of inhibitor of differentiation 4 messenger RNA has been demonstrated in psoriatic skin, but the...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2011.02.005
更新日期:2011-12-01 00:00:00
abstract::A century or so ago, pediatrics and pediatric pathology did not exist. Then, many fetuses/newborns died in utero or shortly after birth. With time, the issue of sepsis was addressed, and a greater number of newborns survived. Gradually, in this soil, the disciplines of pediatrics and pediatric nursing arose, as some r...
journal_title:Human pathology
pub_type: 杂志文章,评审
doi:10.1016/j.humpath.2009.06.017
更新日期:2010-03-01 00:00:00
abstract::Intraductal carcinoma of the prostate (IDC-P) and high-grade prostatic intraepithelial neoplasia (HGPIN) are two distinct intraductal lesions; the former is usually associated with invasive carcinoma and has an aggressive course while the latter is considered a precancerous lesion. In addition, there are morphological...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2014.03.011
更新日期:2014-08-01 00:00:00
abstract::The reticulin stain is a critical diagnostic aide used to differentiate benign hepatocellular proliferations from well differentiated hepatocellular carcinoma (HCC). Rarely, however, hepatocellular carcinomas do not show definitive loss of reticulin in liver biopsy specimens. To study this group of tumors, 11 HCC with...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2020.09.015
更新日期:2021-01-01 00:00:00
abstract::This report reviews the goals and objectives of residency training in pathology as defined during the initial two conferences of program directors. Specific emphasis is given to future needs and in particular the background and capabilities of the persons who will be practicing pathology in the 1980's and 1990's. In t...
journal_title:Human pathology
pub_type: 杂志文章
doi:
更新日期:1980-09-01 00:00:00
abstract::Gastric heterotopia of the intestinal tract can have a diverse clinicopathologic presentation, resulting in a diagnostic dilemma. We present a series of four cases, two male and two female patients with age range of 31-82 years, found in the duodenum, jejunum, and transverse colon. The most common and rather unusual c...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2018.01.003
更新日期:2018-04-01 00:00:00
abstract::The expression of insulin-like growth factor 2 (IGF2) and insulin-like growth factor binding protein 2 (IGFBP2) in 11 cases of hepatoblastoma was studied by means of in situ mRNA hybridization using digoxigenin (DIG)-labeled riboprobes. The results showed that both IGF2 and IGFBP2 transcripts are present in hepatoblas...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(95)90005-5
更新日期:1995-08-01 00:00:00
abstract::We studied renal tissues from 203 patients with acquired immunodeficiency syndrome (AIDS). Of the 203 patients, 20 showed light-microscopic changes characteristic of AIDS-associated nephropathy (AAN). Fifteen of the 20 (group A) were examined by immunohistochemistry using Mycoplasma fermentans (incognitus strain)-spec...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(91)90063-u
更新日期:1991-01-01 00:00:00
abstract::Clear cell renal cell carcinoma (CCRCC) is the most common renal cell carcinoma. It has a relatively unfavorable prognosis compared to other common renal cell carcinomas. Recently, comprehensive molecular studies in CCRCC revealed important genetic alterations, including changes in the VHL, PBRM1, and ARID1A genes. Th...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2014.12.002
更新日期:2015-03-01 00:00:00
abstract::Schistosoma haematobium infection is a common occurrence in Africa and the Middle East and is the world's leading cause of hematuria. Since more North Americans are venturing into endemic areas and more residents of endemic areas are seeking medical care in North America, pathologists must be able not only to diagnose...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(86)80456-7
更新日期:1986-04-01 00:00:00
abstract::Endocrine-paracrine (APUD, neuroendocrine) cells are located in the prostatic ductal and acinar epithelium. These cells are of the open and closed type and have dendritic processes. There is a wide range of secretory granule morphology presumably indicating a variety of different cell "types." Secretory immunoreactive...
journal_title:Human pathology
pub_type: 杂志文章,评审
doi:10.1016/0046-8177(92)90110-o
更新日期:1992-03-01 00:00:00
abstract::Mucoepidermoid carcinoma is a common salivary gland malignancy characterized by genetic heterogeneity as well as cellular diversity of its neoplastic components, which include mucinous cells, epidermoid cells and intermediate cells. The clonal and genetic relationship between each component has not been investigated b...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2016.05.022
更新日期:2016-10-01 00:00:00
abstract::Renal biopsy specimens from 19 patients with asymptomatic hematuria, normal glomeruli on light microscopic examination, and negative immunofluorescence were studied to characterize the ultrastructural changes of the glomerular basement membrane. Three groups of patients were identified. Four patients (group 1) had typ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(83)80180-4
更新日期:1983-11-01 00:00:00
abstract::Plasma cells are the hallmark of chronic endometritis but are not specific for upper tract infection. Plasma cells have also been noted in hormonally mediated endometrial disorders in association with gland architectural changes ("disordered proliferative" and "anovulatory" patterns), and stromal breakdown. We reviewe...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2006.09.002
更新日期:2007-04-01 00:00:00
abstract::Liver parenchymal cells (hepatocytes) have a low rate of turnover, but can nevertheless mount a rapid and efficient regenerative response. However, in some cases of extreme hepatotoxicity hepatocyte proliferation is restricted or even abolished, and instead biliary epithelial cells, commonly referred to as ductular ov...
journal_title:Human pathology
pub_type: 杂志文章,评审
doi:10.1016/s0046-8177(96)90212-9
更新日期:1996-09-01 00:00:00
abstract::Although T-lineage large granular lymphocyte (LGL) leukemia has been described for over 20 years, many patients with this neoplasm go unrecognized. Chief among the difficulties in diagnosing this entity is that the morphologic features are nonspecific and that it is difficult to distinguish it from reactive processes....
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1053/hupa.2000.19298
更新日期:2000-10-01 00:00:00