Parakeratosis in skin is associated with loss of inhibitor of differentiation 4 via promoter methylation.

abstract：:Solitary fibrous tumors (SFTs) often involve the pleura and also may encompass the peritoneum and nonserosal sites. On occasion SFTs mimics other neoplasms, including desmoplastic mesothelioma. CD-34, initially characterized as a hematopoietic progenitor cell antigen, recently has been identified in a small number of ...

journal_title：Human pathology

authors： Flint A,Weiss SW

更新日期：1995-04-01 00:00:00

abstract：:Inflammatory pseudotumors (IPs), mostly benign lesions characterized by fibrotic ground tissue and polyclonal mononuclear infiltrate, may affect all organ systems. IPs originating in the central nervous system (IP-CNS) are very rare, and their distinct histopathologic features are poorly characterized. Three otherwise...

journal_title：Human pathology

authors： Häusler M,Schaade L,Ramaekers VT,Doenges M,Heimann G,Sellhaus B

更新日期：2003-03-01 00:00:00

abstract：:Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) is a B-cell neoplasm that is typically CD5 negative. We describe the clinicopathologic, immunophenotypic, and cytogenetic features of 14 cases of CD5+ MALT lymphoma. There were 9 men and 5 women (median age, 68 years; range, 34-87 y...

journal_title：Human pathology

authors： Jaso J,Chen L,Li S,Lin P,Chen W,Miranda RN,Konoplev S,Medeiros LJ,Yin CC

更新日期：2012-09-01 00:00:00

abstract：:Congenital cystic adenomatoid malformation (CCAM) of the lung is a congenital lesion that is sometimes complicated by bronchioloalveolar adenocarcinoma (BAC). In some cases foci of atypical goblet cell hyperplasia (AGCH) can be found within the cysts. It has been proposed that CCAM and AGCH predispose to the developme...

journal_title：Human pathology

authors： Stacher E,Ullmann R,Halbwedl I,Gogg-Kammerer M,Boccon-Gibod L,Nicholson AG,Sheppard MN,Carvalho L,Franca MT,Macsweeney F,Morresi-Hauf A,Popper HH

更新日期：2004-05-01 00:00:00

abstract：:A carcinoma of the urinary bladder with a distinct choriocarcinomatous component that developed in a postmenopausal woman was associated with high titers of circulating chorionic gonadotropin. The diagnosis was supported by histochemical demonstration of human chorionic gonadotropin in syncytial tumor giant cells and ...

journal_title：Human pathology

authors： Gallagher L,Lind R,Oyasu R

更新日期：1984-08-01 00:00:00

abstract：:Brain metastases (BMs) are common complications of adenocarcinomas (ADCs) of the lung and are associated with a poor prognosis. Although an increasing amount of data indicates that dysregulated activity of mammalian target of rapamycin (mTOR) can influence the metastatic potential of various tumors, the role of mTOR c...

journal_title：Human pathology

authors： Krencz I,Sebestyén A,Fábián K,Márk Á,Moldvay J,Khoor A,Kopper L,Pápay J

更新日期：2017-04-01 00:00:00

abstract：:Lymphocytic colitis, previously termed "microscopic colitis", is a clinicopathologic syndrome of watery diarrhea, grossly normal colonoscopy, and mucosal inflammatory changes. Since lymphocytic colitis is a new, incompletely characterized entity, a histopathologic study was performed to compare lymphocytic colitis (n ...

journal_title：Human pathology

authors： Lazenby AJ,Yardley JH,Giardiello FM,Jessurun J,Bayless TM

更新日期：1989-01-01 00:00:00

abstract：:In contrast to long bone osteosarcoma, mandibular osteosarcoma is highly heterogeneous and morphologically overlaps with benign tumors, obscuring diagnosis and treatment selection. Molecular characterization is difficult due to the paucity of available specimens of this rare disease. We aimed to characterize the spect...

journal_title：Human pathology

authors： Guérin M,Thariat J,Ouali M,Bouvier C,Decouvelaere AV,Cassagnau E,Aubert S,Lepreux S,Coindre JM,Valmary-Degano S,Larousserie F,Meilleroux J,Projetti F,Stock N,Galant C,Marie B,Peyrottes I,de Pinieux G,Gomez-Brouchet A

更新日期：2016-04-01 00:00:00

abstract：:The peroxidase-antiperoxidase immunohistochemical technique was employed to stain formalin fixed, paraffin embedded tissue sections from three cases of encephalitis caused by Toxoplasma gondii. We studied two cases of congenital infection and one case of acquired toxoplasmosis occurring in an immunocompromised host. T...

journal_title：Human pathology

authors： Conley FK,Jenkins KA,Remington JS

更新日期：1981-08-01 00:00:00

abstract：:Kidneys from 1864 necropsies performed in Brisbane, Australia, and from 397 necropsies performed in Christchurch, New Zealand, were examined macroscopically and microscopically. Three zonal and three focal patterns of renal medullary calcification were defined: (1) Outer medullary cortical calcification seen in hyperc...

journal_title：Human pathology

authors： Burry AF,Axelsen RA,Trolove P,Saal JR

更新日期：1976-07-01 00:00:00

abstract：:Lymphoepithelial cysts with histological features characteristic of branchial cleft cysts have been reported to occur rarely in the thyroid gland. To our knowledge only six cases of this lesion have been reported. Since these reports brought this entity to our attention, we have noted that intrathyroidal lymphoepithel...

journal_title：Human pathology

authors： Apel RL,Asa SL,Chalvardjian A,LiVolsi VA

更新日期：1994-11-01 00:00:00

abstract：:Because infants rarely suffer coronary artery thrombosis, it is mistakenly assumed that they seldom have significant ischemic myocardial injury. However, ischemic myocardial necrosis (INM) is common in the papillary muscles and subendocardium of stressed newborns and other infants. Standard dissection methods encourag...

journal_title：Human pathology

authors： Donnelly WH,Hawkins H

更新日期：1987-01-01 00:00:00

abstract：:The authors present 11 cases of plexiform neurofibroma (PN) that featured a very characteristic type of cell appearing as multivacuolated mucin-filled cells (MMFC). The 11 cases were obtained after reviewing 109 cases of PN. Six out of 10 patients showed clinical features of neurofibromatosis type 1. The size of PN ra...

journal_title：Human pathology

authors： Michal M,Kazakov DV,Hadravský L,Michalová K,Rychlý B,Michal M

更新日期：2017-02-01 00:00:00

abstract：:We present 1470 surgical resections for thymoma identified in the pathology files of 14 institutions from 11 countries with the purpose of determining and correlating a simplified histological classification of thymoma and pathological staging with clinical outcome. The study population was composed of 720 men and 750...

journal_title：Human pathology

authors： Weissferdt A,Kalhor N,Bishop JA,Jang SJ,Ro J,Petersson F,Wu B,Langman G,Bancroft H,Bi Y,Meng Y,Medeiros F,Brunnstrom H,Spagnolo D,Chai SM,Laycock A,Wakely PE Jr,Elmberger G,Soares FA,Campos AH,Gumurdulu D,Alvara

更新日期：2018-03-01 00:00:00

abstract：:This study assessed squamous cell papillomas of the human esophagus for the presence of human papillomavirus (HPV) and correlated the results with histological features. Twenty-three lesions obtained by endoscopic biopsy from 17 patients were studied, first by in situ hybridization (ISH) for HPV types 6-11, 16-18, 18,...

journal_title：Human pathology

authors： Carr NJ,Bratthauer GL,Lichy JH,Taubenberger JK,Monihan JM,Sobin LH

更新日期：1994-05-01 00:00:00

abstract：:Organ transplant recipients have an increased tumor incidence owing to their immunocompromised state. The origin of such tumors, whether donor or recipient, will have a clinical impact on decision-making concerning immunosuppressive therapy, retransplantation, and for recipients of other organs from the same donors. W...

journal_title：Human pathology

authors： Baehner R,Magrane G,Balassanian R,Chang C,Millward C,Wakil AE,Osorio RW,Waldman FM

更新日期：2000-11-01 00:00:00

abstract：:The clinicopathologic features and immunohistochemical profiles of 14 cases of a distinctive mesenchymal tumor that arises in the superficial lamina propria of the cervix and vagina and is histologically distinguishable from mesodermal (fibroepithelial) stromal polyp, including the cellular (pseudosarcomatous) variant...

journal_title：Human pathology

authors： Laskin WB,Fetsch JF,Tavassoli FA

更新日期：2001-07-01 00:00:00

abstract：:Pilocytic astrocytoma is an infrequently encountered, generally low-grade neoplasm. No study has extensively looked at both cyclin D1 and MIB-1 labeling indices in pilocytic astrocytoma and their relation to clinical outcome. This study retrospectively examines the clinicopathologic features of 48 patients with pilocy...

journal_title：Human pathology

authors： Machen SK,Prayson RA

更新日期：1998-12-01 00:00:00

abstract：:An unusual case of acute respiratory obstruction caused by multicentric granular cell tumors of the laryngotracheobronchial tree is presented. The patient also had granular cell tumors in the tongue, vulva, and chest wall. Multiplicity of the lesions in the left lung and recurrent episodes of intercurrent pulmonary in...

journal_title：Human pathology

authors： Majmudar B,Thomas J,Gorelkin L,Symbas PN

更新日期：1981-03-01 00:00:00

abstract：:Angiotropic lymphoma (AL) is an unusual variant of extranodal lymphoma, characterized by massive proliferation of neoplastic lymphoid cells almost exclusively within blood vessels. Whereas the lymphoid origin of this disease is widely accepted it still remains unclear whether AL is a distinct entity that originates in...

journal_title：Human pathology

authors： Evert M,Lehringer-Polzin M,Möbius W,Pfeifer U

更新日期：2000-07-01 00:00:00

abstract：:The mucin profile of 24 endoscopic biopsies of heterotopic gastric mucosa (HGM) of the upper esophagus in adults and a control group of ten cases of Meckel's diverticula containing heterotopic gastric mucosa were studied with two combined histochemical methods: alcian blue pH 2.5/PAS and high iron diamine/alcian blue ...

journal_title：Human pathology

authors： Bogomoletz WV,Geboes K,Feydy P,Nasca S,Ectors N,Rigaud C

更新日期：1988-11-01 00:00:00

abstract：:We report a tumor arising in the middle ear of a 65-year-old female patient that was composed of an ovarian-type stroma (OS) and an epithelial component. The tumor consisted of irregular, polypoid masses containing multiple variably sized cystic spaces, which were invariably surrounded by the OS. The cystic spaces wer...

journal_title：Human pathology

authors： Michal M,Skálová A,Kazakov DV,Pecková K,Heidenreich F,Grossmann P,Michal M

更新日期：2017-03-01 00:00:00

abstract：:Paget's disease is a skin cancer characterized by characteristic (Paget) cells scattered in the epidermis. Although its prognosis is generally favorable with surgical resection, the clinical outcome turns unfavorable in cases with recurrence and metastasis. Therefore, establishment of effective therapeutic regimens is...

journal_title：Human pathology

authors： Ogawa T,Nagashima Y,Wada H,Akimoto K,Chiba Y,Nagatani T,Inayama Y,Yao M,Aoki I,Ikezawa Z

更新日期：2005-12-01 00:00:00

abstract：:Polymer substances are commonly applied as surface coatings on endovascular catheters and vascular devices. Adverse effects related to their use have been reported, although the overall clinical significance and appropriate methods of detection of these complications have been unclear. In this analysis, we systematica...

journal_title：Human pathology

authors： Mehta RI,Mehta RI

更新日期：2016-07-01 00:00:00

abstract：:Small cell undifferentiated carcinoma (oat cell carcinoma) is a malignant epithelial neoplasm with neuroendocrine features. It can appear as a primary tumor in many organs besides the lung, including the colon. We report a case of primary small cell undifferentiated carcinoma of the left colon with omental metastases ...

journal_title：Human pathology

authors： Zirkin HJ,Levy J,Katchko L

更新日期：1996-09-01 00:00:00

abstract：:Fabry disease is an X-linked lysosomal storage disease caused by deficiency of α-galactosidase A, resulting in the accumulation of globotriaosylceramide. Many women experience symptoms, but the understanding of placental and fetal aspects of the disease is limited. We report the pregnancy outcome in and placental path...

journal_title：Human pathology

authors： Thurberg BL,Politei JM

更新日期：2012-04-01 00:00:00

abstract：:Cell growth in the normal prostate is regulated by a delicate balance between cell death and cell proliferation (ie, apoptotic v proliferative activity). Disruption of the molecular mechanisms that regulate these two processes may underline the abnormal growth of the gland leading to benign prostatic hyperplasia (BPH)...

journal_title：Human pathology

authors： Kyprianou N,Tu H,Jacobs SC

更新日期：1996-07-01 00:00:00

abstract：:A cytogenetic study of an eccrine spiradenoma and two lymph node metastases, with a growth pattern and microscopic appearance typical for benign eccrine spiradenoma, revealed a 46,XY-5,del(16)(q22),+mar(t(?;5)(?::5q13----5qter)) karyotype. The finding of the same abnormal karyotype in the tumor and the metastases sugg...

journal_title：Human pathology

authors： Dijkhuizen T,van den Berg E,Nikkels PG,Hoekstra HJ,de Jong B

更新日期：1992-09-01 00:00:00

abstract：:Intraductal carcinoma of the prostate (IDC-P) and high-grade prostatic intraepithelial neoplasia (HGPIN) are two distinct intraductal lesions; the former is usually associated with invasive carcinoma and has an aggressive course while the latter is considered a precancerous lesion. In addition, there are morphological...

journal_title：Human pathology

authors： Miyai K,Divatia MK,Shen SS,Miles BJ,Ayala AG,Ro JY

更新日期：2014-08-01 00:00:00

abstract：:We have experienced an autopsy case of a 20-year-old woman with bronchiolitis obliterans, pemphigus vulgaris, and Castleman's disease. The affected bronchioles showed almost the same histology as previously described. But, the number of the lesions seemed too small to cause her death of respiratory insufficiency. We a...

journal_title：Human pathology

authors： Saito K,Morita M,Enomoto K

更新日期：1997-11-01 00:00:00