Oncocytic variant of malignant gastrointestinal neuroectodermal tumor: a potential diagnostic pitfall.

abstract：:Two undifferentiated (embryonal) sarcomas of liver were studied ultrastructurally and immunohistochemically. Electron microscopic examination of the pleomorphic tumor cells revealed fibroblastic and histiocytic characteristics. There were no specific findings to support rhabdomyoblastic, leiomyoblastic, or epithelial ...

journal_title：Human pathology

authors： Keating S,Taylor GP

更新日期：1985-07-01 00:00:00

abstract：:Autopsy rates continue to decline despite abundant evidence of the autopsy's value. Such an extraordinary contradiction requires that we look beyond issues of education to consider our basic moral and political commitments; to consider, in other words, the kind of society in which we live, and the kind of people we ar...

journal_title：Human pathology

authors： Vance RP

更新日期：1990-02-01 00:00:00

abstract：:Primitive neuroectodermal tumors are morphologically similar malignant tumors arising in intracranial and peripheral sites of the nervous system, showing varying degrees of cellular differentiation with a tendency to disseminate along cerebrospinal fluid pathways. They occur primarily in children and young adults. Und...

journal_title：Human pathology

authors： Becker LE,Hinton D

更新日期：1983-06-01 00:00:00

abstract：:A digoxigenin-tailed, synthetic oligodeoxynucleotide was used to detect genomic hepatitis delta virus (HDV) RNA in formalin-fixed, paraffin-embedded liver sections by a nonisotopic in situ hybridization (NISH) procedure. Twenty-three liver samples from chronically HDV-infected patients were studied. Eight liver specim...

journal_title：Human pathology

authors： Pacchioni D,Negro F,Chiaberge E,Rizzetto M,Bonino F,Bussolati G

更新日期：1992-05-01 00:00:00

abstract：:A critical area of chromosomal loss at region p16(9p21-22) and p53(17p13) has been implicated in the genesis of malignant melanoma. It is still unclear whether the genetic alterations can be detected in dysplastic nevus, a premalignant lesion of malignant melanoma. We have searched the frequency of p16 and p53 deletio...

journal_title：Human pathology

authors： Park WS,Vortmeyer AO,Pack S,Duray PH,Böni R,Guerami AA,Emmert-Buck MR,Liotta LA,Zhuang Z

更新日期：1998-02-01 00:00:00

abstract：:Tumor cell adhesion, detachment, and aggregation play an important part in tumor invasion and metastasis, and a variety of cell adhesion molecules have been found on tumor cells. Cell adhesion molecules, including those of the immunoglobulin superfamily, are associated with the development of metastatic behavior in cu...

journal_title：Human pathology

authors： Mooy CM,Luyten GP,de Jong PT,Jensen OA,Luider TM,van der Ham F,Bosman FT

更新日期：1995-11-01 00:00:00

abstract：:Abnormal nuclear megakaryocytic staining for phospho-STAT5 (pSTAT5) correlates with JAK2 V617F mutational status in non-chronic myelogenous leukemia chronic myeloproliferative disorders. However, a proportion of wild-type JAK2 non-chronic myelogenous leukemia chronic myeloproliferative disorders cases also demonstrate...

journal_title：Human pathology

authors： Gibson SE,Schade AE,Szpurka H,Bak B,Maciejewski JP,Hsi ED

更新日期：2008-07-01 00:00:00

abstract：:The histogenesis of colloid cysts (CCs) of the third ventricle has been a subject of controversy. We examined, using immunohistochemical techniques, four CCs for the presence of cytokeratins (CKs), glutathione S-transferase isoenzymes (GST-pi, GST-mu), and glial fibrillary acidic protein. Antibodies to both low molecu...

journal_title：Human pathology

authors： Tsuchida T,Hruban RH,Carson BS,Phillips PC

更新日期：1992-07-01 00:00:00

abstract：:Hepatic artery thrombosis (HAT) following orthotopic liver transplantation (OLT) can cause hepatic parenchymal necrosis and ischemic cholangiopathy. This study investigates additional histologic features that may suggest HAT in post-OLT liver specimens. For 94 liver specimens (explanted allografts and biopsies) from p...

journal_title：Human pathology

authors： Lee M,Agostini-Vulaj D,Gonzalez RS

更新日期：2019-08-01 00:00:00

abstract：:Pulmonary endodermal tumor resembling fetal lung describes an uncommon neoplasm of the lung which also has been referred to as pulmonary blastoma and adenocarcinoma of fetal lung type. We describe five cases which fall within a narrow band on the spectrum of pulmonary neoplasms with both epithelial and mesenchymal fea...

journal_title：Human pathology

authors： Nakatani Y,Dickersin GR,Mark EJ

更新日期：1990-11-01 00:00:00

abstract：:K homology domain containing protein overexpressed in cancer (KOC) is a member of the insulin-like growth factor (IGF) messenger RNA-binding protein family and is expressed during embryogenesis and in certain malignancies. KOC, known as L523S and IGF messenger RNA-binding protein 3, was shown to be frequently expresse...

journal_title：Human pathology

authors： Xu H,Bourne PA,Spaulding BO,Wang HL

更新日期：2007-04-01 00:00:00

abstract：:Ten cases of reactive follicular hyperplasia and 31 cases of B-cell non-Hodgkin's malignant lymphoma were studied using multiparameter flow cytometry. A bimodal distribution for HLA-DR expression, but not for surface immunoglobulin or B cell-specific antigens CD19 and CD20, was observed commonly in mixed cell type and...

journal_title：Human pathology

authors： Ratech H

更新日期：1990-12-01 00:00:00

abstract：:Recently, a novel tumor-associated protein, termed MN, has been described in carcinomas of the uterine cervix, where its expression has been shown to be associated with malignant transformation. Because malignant transformation in the esophagus develops through a dysplasia-carcinoma sequence similar to that which occu...

journal_title：Human pathology

authors： Turner JR,Odze RD,Crum CP,Resnick MB

更新日期：1997-06-01 00:00:00

abstract：:Calcitonin and calcitonin gene-related peptide (CGRP) have been localized immunohistochemically in neuroendocrine cells of normal and diseased human lungs. Cells immunoreactive for calcitonin and CGRP first appeared in immature bronchi in the 27th gestational week. Thereafter, both peptides were found in the same bron...

journal_title：Human pathology

authors： Tsutsumi Y

更新日期：1989-09-01 00:00:00

abstract：:Alterations of the epidermal growth factor receptor (EGFR) can be observed in a significant subset of esophageal adenocarcinomas (EACs), and targeted therapy against EGFR may become an interesting approach for the treatment of these tumors. Mutations of KRAS, NRAS, BRAF, and phosphatidylinositol-3-kinase catalytic sub...

journal_title：Human pathology

authors： Bettstetter M,Berezowska S,Keller G,Walch A,Feuchtinger A,Slotta-Huspenina J,Feith M,Drecoll E,Höfler H,Langer R

更新日期：2013-05-01 00:00:00

abstract：:This article briefly describes the origin of one of the more common (food-related) pathologic terms--"bread and butter pericarditis." The eminent French physician, Laennec, the inventor of the stethoscope amongst several other important medical contributions, can be credited for having coined the term that is still in...

journal_title：Human pathology

authors： Cohen MB

更新日期：2004-02-01 00:00:00

abstract：:Fluorescent (FISH) and chromogenic (CISH) in situ hybridization have recently become part of the diagnostic armamentarium of breast pathologists. HER2 gene testing by FISH and/or CISH has become an integral part of the diagnostic workup for patients with breast cancer. In this era of high throughput technologies, thes...

journal_title：Human pathology

authors： Lambros MB,Natrajan R,Reis-Filho JS

更新日期：2007-08-01 00:00:00

abstract：:T-prolymphocytic leukemia (T-PLL) is a rare mature T-cell neoplasm characterized by proliferation of prolymphocytes. Most cases involve the T-cell leukemia-1 (TCL1) gene at 14q11.2 resulting in overexpression of TCL-1, which is helpful for distinguishing T-PLL from other T-cell neoplasms. We report a patient with T-PL...

journal_title：Human pathology

authors： Hu Z,Li S,Medeiros LJ,Sun T

更新日期：2017-07-01 00:00:00

abstract：:In the past decade most studies of coronary arterial aneurysms have been clinical; few have focused on morphology and etiopathogenesis. The subjects of the present autopsy study were 52 patients, 5 months to 80 years of age, with coronary arterial aneurysms. Patients were divided into two groups: 38 with atherosclerot...

journal_title：Human pathology

authors： Virmani R,Robinowitz M,Atkinson JB,Forman MB,Silver MD,McAllister HA

更新日期：1986-06-01 00:00:00

abstract：:α-Thalassemia/mental retardation syndrome X-linked protein (ATRX) and death domain-associated protein (DAXX) genes are tumor suppressors whose mutations have been identified in sporadic pancreatic neuroendocrine tumors as well as in patients with MEN1. However, it is unknown whether ATRX and DAXX alterations are speci...

journal_title：Human pathology

authors： Chen SF,Kasajima A,Yazdani S,Chan MS,Wang L,He YY,Gao HW,Sasano H

更新日期：2013-10-01 00:00:00

abstract：:Previous studies indicated that microRNA (miR)-675 and its precursor lncRNA H19 were both overexpressed in glioma tissues, and H19 might play an oncogenic role. To investigate the involvement of miR-675 in gliomas and its underlying mechanisms, we here collected candidate target genes of miR-675-5p from miRTarBase (ht...

journal_title：Human pathology

authors： Zheng Y,Lu X,Xu L,Chen Z,Li Q,Yuan J

更新日期：2017-11-01 00:00:00

abstract：:It has been suggested that atypical adenomatous hyperplasia (AAH) may be a precursor of peripheral adenocarcinoma of the lung. Telomerase is a ribonucleoprotein enzyme that synthesizes telomeric DNA onto chromosomal ends. Its activity is believed to be crucial for cellular immortality, and it is thought to participate...

journal_title：Human pathology

authors： Nakanishi K,Kawai T,Kumaki F,Hirot S,Mukai M,Ikeda E

更新日期：2002-07-01 00:00:00

abstract：:Bone marrow biopsy findings in 32 homosexual patients with the acquired immunodeficiency syndrome (AIDS) or prodromal AIDS are described. A high incidence (38 per cent) of nonparatrabecular lymphohistiocytic infiltrations containing irregular small lymphocytes was observed, as well as the presence of diffuse bone marr...

journal_title：Human pathology

authors： Osborne BM,Guarda LA,Butler JJ

更新日期：1984-11-01 00:00:00

abstract：:Oral cancer overexpressed 1 (ORAOV1) has been reported to exhibit high amplification levels in esophageal squamous cell cancer (ESCC) and in premalignant lesions. However, ORAOV1 protein expression levels in ESCC and esophageal squamous intraepithelial neoplasia (ESIN) have not yet been reported. We have explored the ...

journal_title：Human pathology

authors： Li M,Cui X,Shen Y,Dong H,Liang W,Chen Y,Hu J,Li S,Kong J,Li H,Zhao J,Li F

更新日期：2015-05-01 00:00:00

abstract：:Bone Marrow Transplant (BMT) is a critical therapeutic intervention for a variety of diseases occurring in the pediatric patient. Complications of allogeneic BMT include graft-versus-host disease (GVHD), infection, drug toxicity, thrombotic microangiopathy, and veno-occlusive disease. With solid organ transplantation,...

journal_title：Human pathology

authors： Selby DM,Rudzki JR,Bayever ES,Chandra RS

更新日期：1999-07-01 00:00:00

abstract：:Telomerase, the enzyme that stabilizes telomere length, is reactivated with almost all cancer types, and it may be necessary for unlimited cell proliferation. Assessment of malignancy in ordinary meningiomas is inconclusive because no clear-cut correlation exists between aggressive clinical behavior and histological f...

journal_title：Human pathology

authors： Langford LA,Piatyszek MA,Xu R,Schold SC Jr,Wright WE,Shay JW

更新日期：1997-04-01 00:00:00

abstract：:We herein report an 18-month-old girl who presented with a retroperitoneal mature teratoma that later developed into an endodermal sinus tumor. Her symptoms included an expanding abdominal girth. The serum levels of alpha-fetoprotein were moderately elevated. The excised specimen was a benign mature cystic retroperito...

journal_title：Human pathology

authors： Ohno Y,Kanematsu T

更新日期：1998-10-01 00:00:00

abstract：:A 57 year old man presented with a two week history of right sided chest pain. An admission chest x-ray examination revealed a 2 by 1 cm. lytic lesion of the ninth right rib and right sided pleural effusion. The patient underwent a right thoracotomy during which 700 cc. of blood tinged pleural fluid was drained and a ...

journal_title：Human pathology

authors： Pappas CA,Rheinlander HF,Stadecker MJ

更新日期：1980-11-01 00:00:00

abstract：:Multicentric Castleman disease (MCD) is a systemic inflammatory disease potentially caused by an increase in the serum interleukin-6 (IL-6) level. Idiopathic MCD (iMCD) is histopathologically classified into three types: plasmacytic (PC), mixed, and hypervascular (hyperV) types. Recently, a unique clinical phenotype w...

journal_title：Human pathology

authors： Kurose N,Futatsuya C,Mizutani KI,Kumagai M,Shioya A,Guo X,Aikawa A,Nakada S,Fujimoto S,Kawabata H,Masaki Y,Takai K,Aoki S,Kojima M,Nakamura S,Yamada S

更新日期：2018-07-01 00:00:00

abstract：:Focal apocrine metaplasia was studied in 293 whole human breasts by a subgross sampling technique with histologic confirmation. There were 186 breasts obtained from random autopsies. Another 107 breasts were obtained that were cancer-associated; these breasts either contained an invasive cancer or were situated contra...

journal_title：Human pathology

authors： Wellings SR,Alpers CE

更新日期：1987-04-01 00:00:00