Abstract：
:Bone marrow biopsy findings in 32 homosexual patients with the acquired immunodeficiency syndrome (AIDS) or prodromal AIDS are described. A high incidence (38 per cent) of nonparatrabecular lymphohistiocytic infiltrations containing irregular small lymphocytes was observed, as well as the presence of diffuse bone marrow damage with plasmacytosis (22 per cent), decreased or absent stainable iron (50 per cent), and histologically identifiable pathogenic organisms (6 per cent). Morphologically, the lymphohistiocytic infiltrations are indistinguishable from bone marrow involvement by peripheral T-cell lymphoma, which may cause confusion, especially when a concurrent lymph node biopsy is difficult to interpret. On deeper sectioning, a specimen from one patient assumed a more granulomatous appearance. Specimens from two patients with small, poorly formed noncaseating granulomas contained demonstrable organisms.
journal_name
Hum Patholjournal_title
Human pathologyauthors
Osborne BM,Guarda LA,Butler JJdoi
10.1016/s0046-8177(84)80248-8subject
Has Abstractpub_date
1984-11-01 00:00:00pages
1048-53issue
11eissn
0046-8177issn
1532-8392pii
S0046-8177(84)80248-8journal_volume
15pub_type
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