Adenocarcinoma of the lung: a comparative diagnostic study using light and electron microscopy.

abstract：:Twelve cases of pure adenoid cystic carcinoma of the breast were reviewed. Patients ranged in age from 34 to 69 years. Seven carcinomas were in the right breast, and five in the left; five of the 12 were located in the central region of the breast, five in the upper outer quadrant, and the two in the upper inner and l...

journal_title：Human pathology

authors： Ro JY,Silva EG,Gallager HS

更新日期：1987-12-01 00:00:00

abstract：:Nonalcoholic steatohepatitis (NASH) refers to an alcoholic hepatitis-like histologic pattern found in nonalcoholic patients. A review of 543 liver biopsies diagnosed as alcoholic hepatitis yielded 49 cases of NASH. The patients were commonly middle-aged women who were obese and often diabetic. NASH was usually discove...

journal_title：Human pathology

authors： Lee RG

更新日期：1989-06-01 00:00:00

abstract：:We report three cases of follicular dendritic cell sarcoma (FDCS) showing a hitherto undescribed histological pattern consisting of nodular tumor growth associated with small B lymphocytes. FDCS tumor cells consistently showed large epithelioid features and were intermingled with small lymphocytes in the nodules in tw...

journal_title：Human pathology

authors： Lorenzi L,Lonardi S,Petrilli G,Tanda F,Bella M,Laurino L,Rossi G,Facchetti F

更新日期：2012-02-01 00:00:00

abstract：:Fifty-three pure mucinous carcinomas of breast were studied, with long-term follow-up evaluation (average, 15 years) for 37. The mean age of the patients was 63 years. Long-term survival (Kaplan-Meier method) was 68 per cent, excluding non-tumor-related deaths. Median survival for the patients with fatal carcinomas wa...

journal_title：Human pathology

authors： Clayton F

更新日期：1986-01-01 00:00:00

abstract：:Hepatoid adenocarcinoma is an extrahepatic tumor characterized by morphological similarities to hepatocellular carcinoma. The lesions contain a tubular adenocarcinoma that seems to develop "hepatoid" features, but the relation between the tubular adenocarcinomatous and the hepatoid components remains unclear. We compa...

journal_title：Human pathology

authors： Kumashiro Y,Yao T,Aishima S,Hirahashi M,Nishiyama K,Yamada T,Takayanagi R,Tsuneyoshi M

更新日期：2007-06-01 00:00:00

abstract：:Mucus-filled cystic tumors of low or borderline malignant potential, well recognized in ovary and appendix, have received little attention in the lung. We present data on 11 patients, all of whom had solitary pulmonary nodules resected in which mucus was the major histologic component. Prognosis appears good; no patie...

journal_title：Human pathology

authors： Graeme-Cook F,Mark EJ

更新日期：1991-02-01 00:00:00

abstract：:This article considers the NHS cervical screening program and the controversies which have attended the introduction of comprehensive screening in a partially screened population of women in whom the underlying risk of disease was unknown. The increase in screening coverage which has taken place since 1988 has coincid...

journal_title：Human pathology

authors： Herbert A

更新日期：1997-02-01 00:00:00

abstract：:Cervical carcinoma is the most common cancer among Belizean women; however, data regarding the frequency of human papillomavirus (HPV) genotypes and their association with cervical cancer are nonexistent. We therefore included HPV genotyping as part of a week-long cervical cancer screening campaign conducted in Belize...

journal_title：Human pathology

authors： Cathro HP,Loya T,Dominguez F,Howe SL,Howell R,Orndorff K,Moreno J,Mendez E,Fung PC,Beer NL,Allen P,Sosa AM,Gurka KK,Stoler MH,Frierson HF Jr

更新日期：2009-07-01 00:00:00

abstract：:Renal biopsy specimens from 19 patients with asymptomatic hematuria, normal glomeruli on light microscopic examination, and negative immunofluorescence were studied to characterize the ultrastructural changes of the glomerular basement membrane. Three groups of patients were identified. Four patients (group 1) had typ...

journal_title：Human pathology

authors： Yum M,Bergstein JM

更新日期：1983-11-01 00:00:00

abstract：:Meconium-associated vascular necrosis (MAVN) is a histological abnormality of human placental chorionic vessels that is associated with poor neonatal outcome. We tested the hypothesis that MAVN shows apoptosis in the walls of chorionic vessels. Archival placental specimens with MAVN (n = 5) were compared with specimen...

journal_title：Human pathology

authors： King EL,Redline RW,Smith SD,Kraus FT,Sadovsky Y,Nelson DM

更新日期：2004-04-01 00:00:00

abstract：:The synovium in two well-documented cases of alkaptonuric ochronosis was studied by transmission electron and light microscopy. A feature of alkaptonuria previously unreported in the English-language literature was the presence of phagocytosis of large collagen fibrils by synovial macrophages in both cases. The origin...

journal_title：Human pathology

authors： Gaines JJ Jr,Tom GD,Khankhanian N

更新日期：1987-11-01 00:00:00

abstract：:The types of collagen present in a case of elastofibroma dorsi were determined using type specific, characterized collagen antibodies. The presence of type II collagen (normally present only in articular cartilage and in selected ocular structures) is discussed with regard to the pathogenesis of this lesion, and the u...

journal_title：Human pathology

authors： Madri JA,Dise CA,LiVolsi VA,Merino MJ,Bibro MC

更新日期：1981-02-01 00:00:00

abstract：:Endolymphatic sac tumor (ELST) is a low-grade adenocarcinoma of the temporal bone that is presumed to originate from the endolymphatic system. Although ELSTs are extremely rare in the general population, a significant number of studies have documented the occurrence of ELST among patients with von Hippel-Lindau (VHL) ...

journal_title：Human pathology

authors： Hamazaki S,Yoshida M,Yao M,Nagashima Y,Taguchi K,Nakashima H,Okada S

更新日期：2001-11-01 00:00:00

abstract：:CpG island methylator phenotype (CIMP) pathway in colorectal cancer is characterized by methylation of promoter regions of multiple putative tumor suppressor genes. Aberrant methylation also occurs in serrated and adenomatous polyps. We examined 32 tubulovillous/villous adenomas and 30 tubular adenomas for BRAF/KRAS m...

journal_title：Human pathology

authors： Kakar S,Deng G,Cun L,Sahai V,Kim YS

更新日期：2008-01-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) infection is usually reported in immunocompromised patients. This study reports 11 cases of HCMV infection of the gastrointestinal (GI) tract diagnosed in apparently immunocompetent hosts. The median age of the patients studied was 76 years, and the major presenting symptoms were diarrhea,...

journal_title：Human pathology

authors： Maiorana A,Baccarini P,Foroni M,Bellini N,Giusti F

更新日期：2003-12-01 00:00:00

abstract：:In a large-scale analysis of gene expression in pancreatic cancer, we isolated the homologue of the mouse Rab20. The mouse protein was previously identified during a search for novel Rab proteins, a family of small GTP-binding proteins involved in the regulation of intracellular vesicular transport. The Rab20 protein ...

journal_title：Human pathology

authors： Amillet JM,Ferbus D,Real FX,Antony C,Muleris M,Gress TM,Goubin G

更新日期：2006-03-01 00:00:00

abstract：:Hypertrophic cardiomyopathy phenotype is shared by heterogeneous entities. The purpose of the study was to evaluate the diagnostic role of left ventricular endomyocardial biopsy. One hundred fifty-one consecutive patients with unexplained left ventricular hypertrophy and normal/elevated QRS voltages or left bundle-bra...

journal_title：Human pathology

authors： Frustaci A,Russo MA,Chimenti C

更新日期：2013-01-01 00:00:00

abstract：:We studied renal tissues from 203 patients with acquired immunodeficiency syndrome (AIDS). Of the 203 patients, 20 showed light-microscopic changes characteristic of AIDS-associated nephropathy (AAN). Fifteen of the 20 (group A) were examined by immunohistochemistry using Mycoplasma fermentans (incognitus strain)-spec...

journal_title：Human pathology

authors： Bauer FA,Wear DJ,Angritt P,Lo SC

更新日期：1991-01-01 00:00:00

abstract：:We have begun a systematic study of human papillomavirus (HPV) infection in colposcopically and/or morphologically normal epithelium of the uterine cervix. Paired biopsies were taken from the lesions (cervical intraepithelial neoplasia [CIN], condyloma, invasive carcinoma) and from the normal-appearing adjacent epithe...

journal_title：Human pathology

authors： Colgan TJ,Percy ME,Suri M,Shier RM,Andrews DF,Lickrish GM

更新日期：1989-04-01 00:00:00

abstract：:Complete age-related regression of mammary epithelium, often termed postmenopausal involution, is associated with decreased breast cancer risk. However, most studies have qualitatively assessed involution. We quantitatively analyzed epithelium, stroma, and adipose tissue from histologically normal breast tissue of 454...

journal_title：Human pathology

authors： Sandhu R,Chollet-Hinton L,Kirk EL,Midkiff B,Troester MA

更新日期：2016-02-01 00:00:00

abstract：:The case of a biliary cystadenoma containing foci of cystadenocarcinoma is reported, along with the first electron microscopic description of this lesion. Both neoplastic and congenital origins have been implicated in the pathogenesis of biliary cystadenomas. In this case hamartomatous bile ducts were found, supportin...

journal_title：Human pathology

authors： Devine P,Ucci AA

更新日期：1985-01-01 00:00:00

abstract：:Penile carcinoma (PC) is more frequent in underdeveloped countries, generally is diagnosed at an advanced stage when therapeutic options are restricted, and thus is associated with high morbidity/mortality rates. Recent studies have demonstrated clinical benefits with epidermal growth factor receptor (EGFR)-targeted t...

journal_title：Human pathology

authors： Silva Amancio AM,Cunha IW,Neves JI,Quetz JD,Carraro DM,Rocha RM,Zequi SC,Cubilla AL,da Fonseca FP,Lopes A,Cunha MD,Lima MV,Vassallo J,Guimarães GC,Soares FA

更新日期：2017-03-01 00:00:00

abstract：:The control of colorectal cancer is currently dependent on early detection, and its prevention requires the recognition and treatment of its precursor lesions. The adenoma has been established as the precursor of colorectal carcinoma in the general population. Among patients with inflammatory bowel disease (IBD), dysp...

journal_title：Human pathology

authors： Pascal RR

更新日期：1994-11-01 00:00:00

abstract：:Human epidermal growth factor receptor 2 (HER2) status is useful for predicting response to trastuzumab. Fluorescence in situ hybridization (FISH) for HER2 gene amplification is accurate but limited because of cost, the need for fluorescence microscopy, the limited assessment of histology, and the fading of its signal...

journal_title：Human pathology

authors： Lim SJ,Cantillep A,Carpenter PM

更新日期：2013-11-01 00:00:00

abstract：:Granulocyte alloantibodies and autoantibodies have a key role in the pathophysiology of several clinical problems. These include febrile transfusion reactions, severe pulmonary reactions to transfusion, isoimmune neonatal neutropenia, failure of effective granulocyte transfusion, autoimmune neutropenia, drug-induced n...

journal_title：Human pathology

authors： McCullough J

更新日期：1983-03-01 00:00:00

abstract：:Two undifferentiated (embryonal) sarcomas of liver were studied ultrastructurally and immunohistochemically. Electron microscopic examination of the pleomorphic tumor cells revealed fibroblastic and histiocytic characteristics. There were no specific findings to support rhabdomyoblastic, leiomyoblastic, or epithelial ...

journal_title：Human pathology

authors： Keating S,Taylor GP

更新日期：1985-07-01 00:00:00

abstract：:Clinicopathological and cytogenetic studies were performed on specimens from 43 patients with CD30-positive anaplastic large cell lymphoma (ALCL). All patients were born and lived in a human T-cell lymphotropic virus (HTLV)-I endemic area. Twenty-one patients (48.8%) had serum anti-HTLV-I antibody suggesting the prese...

journal_title：Human pathology

authors： Takeshita M,Ohshima K,Akamatsu M,Ohgami A,Kikuchi M,Suzumiya J,Uike N,Okamura T,Nakayama J

更新日期：1995-06-01 00:00:00

abstract：:We studied the histopathologic, immunohistochemical, and ultrastructural features of the extracellular matrix (ECM) in 20 immunologically defined large-cell lymphomas, including immunoblastic sarcoma of B cells (three patients), peripheral T cell lymphoma (five patients), large non-cleaved follicular center cell (FCC)...

journal_title：Human pathology

authors： McCurley TL,Gay RE,Gay S,Glick AD,Jones MR,Haralson MA,Collins RD

更新日期：1989-02-01 00:00:00

abstract：:We evaluated 173 consecutive breast carcinomas for c-erbB-2 using a combination of immunohistochemistry (IHC) with a commercial polyclonal antibody (Nitirei) and dual-color fluorescence in situ hybridization (FISH) using the c-erbB-2-specific probe and the chromosome 17 centromere-specific probe from Vysis (Downers Gr...

journal_title：Human pathology

authors： Kobayashi M,Ooi A,Oda Y,Nakanishi I

更新日期：2002-01-01 00:00:00

abstract：:The light microscopic diagnosis of large cell undifferentiated carcinoma of the lung is known to be highly subjective and shows poor interobserver reproducibility; the very existence of this tumor as a separate entity has been challenged. The ultrastructure of seven large cell undifferentiated carcinomas was examined ...

journal_title：Human pathology

authors： Churg A

更新日期：1978-03-01 00:00:00