Abstract:
:Patients undergoing treatment of acute lymphoblastic leukemia are at risk for fungal infections including disseminated candidiasis. We describe a case of systemic Candida albicans infection associated with life-threatening gastrointestinal hemorrhage due to unusual necrotizing vasculitis involving the gastrointestinal tract. We explore the association between Candida and such vasculopathy.
journal_name
Hum Patholjournal_title
Human pathologyauthors
Sargent J,O'Marcaigh A,Smith O,Butler K,Gavin P,O'Sullivan Mdoi
10.1016/j.humpath.2009.09.015subject
Has Abstractpub_date
2010-04-01 00:00:00pages
602-4issue
4eissn
0046-8177issn
1532-8392pii
S0046-8177(09)00404-3journal_volume
41pub_type
杂志文章相关文献
HUMAN PATHOLOGY文献大全abstract::Our previous investigations of transforming growth factor types beta 1 and beta 2 (TGF beta s) showed negative or positive autocrine growth regulation of gliomas in vitro. Near-diploid gliomas were inhibited by the TGF beta s, whereas a stimulatory response correlated with progressive anaplasia and karyotypic divergen...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(94)90118-x
更新日期:1994-05-01 00:00:00
abstract::Kaposi's sarcoma (KS) is a pleomorphic spindle cell lesion whose incidence has markedly increased among patients infected with the human immunodeficiency virus (HIV), especially among those whose primary risk factor is homo/bisexual transmission. The question as to whether KS is even a true neoplasm still remains larg...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(92)90112-g
更新日期:1992-03-01 00:00:00
abstract::Two patients, 14 and 46 years of age, presented with diffuse, rapidly growing intracerebral tumors leading to death 6 1/2 and 9 1/2 months, respectively, after diagnosis. Histological examination showed sheets of moderate-sized tumor cells with clear cytoplasm and central nuclei interrupted by delicate arciform vascul...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(94)90242-9
更新日期:1994-08-01 00:00:00
abstract::To investigate the roles of matrix metalloproteinases (MMPs) in thymic epithelial tumors, we examined the expression of MMP-2, -7, and -9; membrane-type 1 (MT1)-MMP; and tissue inhibitor of metalloproteinase-2 (TIMP-2) in 57 tumors by immunohistochemistry and in selected 15 cases by in situ hybridization. The tumors c...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2003.07.013
更新日期:2003-12-01 00:00:00
abstract::Soft tissue myoepithelial tumors, a recently defined entity, include benign and malignant lesions showing a considerable morphological and immunohistochemical heterogeneity. EWSR1 rearrangements are well recognized in this tumor type, and some of the partner genes have been identified. Herein we describe a soft tissue...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2011.08.004
更新日期:2012-05-01 00:00:00
abstract::In a large-scale analysis of gene expression in pancreatic cancer, we isolated the homologue of the mouse Rab20. The mouse protein was previously identified during a search for novel Rab proteins, a family of small GTP-binding proteins involved in the regulation of intracellular vesicular transport. The Rab20 protein ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2005.10.017
更新日期:2006-03-01 00:00:00
abstract::Benign lymphocytic angiitis and granulomatosis is a T-cell lymphoproliferative disorder confined to the lung and corresponding to a low-grade angiocentric immunoproliferative lesion. Controversy remains as to whether these lesions are lymphomas. We report such a case in an 8-year-old patient with Burkitt's lymphoma in...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(92)90041-z
更新日期:1992-10-01 00:00:00
abstract::We introduce a novel hybrid telepathology system providing simultaneous transmission of both real-time microscopy and static imagery at a reasonable cost. It is capable of capturing static, true color images at resolution of 1,520 x 1,144 pixels and providing live transmission of real-time video images of the glass sl...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1053/hupa.2000.9196
更新日期:2000-07-01 00:00:00
abstract::Differentiation features and proliferation activity of 67 gastric microleiomyomas (microLMs) and 53 clinical gastrointestinal stromal tumors (GISTs) of the stomach were compared. The 67 microLMs were divided into two categories on the basis of cellularity: 53 hypocellular and 14 hypercellular types, and the 39 GISTs w...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(97)90223-9
更新日期:1997-12-01 00:00:00
abstract::Atypical mesothelial hyperplasia encountered in pleural fluid or in a pleural biopsy specimen raises the suspicion that one may be dealing with a diffuse malignant mesothelioma of the pleura. We studied eight cases with cytologic or histologic changes of mesothelial atypia thought to be suspicious for diffuse malignan...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(91)90292-w
更新日期:1991-07-01 00:00:00
abstract::Five hundred eighty renal biopsies from a pool of 27850 archived cases were identified in which a myoglobin stain was performed because of atypical casts. Two hundred and thirty-eight (41%) of these biopsies were found to be positive for myoglobin casts. The morphology of the myoglobin casts ranged from light, almost ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2016.02.026
更新日期:2016-08-01 00:00:00
abstract::Brain metastases (BMs) are common complications of adenocarcinomas (ADCs) of the lung and are associated with a poor prognosis. Although an increasing amount of data indicates that dysregulated activity of mammalian target of rapamycin (mTOR) can influence the metastatic potential of various tumors, the role of mTOR c...
journal_title:Human pathology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.humpath.2016.12.012
更新日期:2017-04-01 00:00:00
abstract::The distinction of malignant mesothelioma from non-small-cell lung carcinoma (NSCLC) usually requires immunohistochemistry, but some broad-spectrum carcinoma markers stain mesotheliomas, and it remains unclear which broad-spectrum markers are most valuable for distinguishing these malignancies. Here, we directly compa...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2020.04.005
更新日期:2020-06-01 00:00:00
abstract::Nasopharyngeal carcinoma (NPC) is a commonly occurring tumor in southern China. Although several causative factors have now been recognized, the genetic basis underlying its tumorigenesis is still unclear. To identify potential chromosomal aberrations for further investigations, comparative genomic hybridization (CGH)...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(00)80216-6
更新日期:2000-02-01 00:00:00
abstract::Insulin-like growth factor II messenger RNA (mRNA)-binding protein 3 (IMP3) is an oncofetal protein that promotes tumor progression and metastasis in a number of malignancies. However, the clinical significance of IMP3 expression in squamous cell carcinoma (SCC) of the uterine cervix is unclear. In this study, the cor...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2014.07.006
更新日期:2014-11-01 00:00:00
abstract::The radiosensitivities of lymphocytes of peripheral blood origin obtained from two healthy 45 year old male donors were studied simultaneously at yearly intervals over a three year period. Hypaque-Ficoll purified cells were exposed in vitro to 0, 5, 50, and 500 rads and then evaluated serially for viability of T and B...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(79)80007-6
更新日期:1979-03-01 00:00:00
abstract::Explants from paraspinal muscles of patients with scoliosis were cultured in Millipore diffusion chambers placed in peritoneal cavities of mice. Three and four weeks of incubation produced a predominantly myogenic growth. Cell counts done on paraffin sections and on dissociated cells from the chambers showed that expl...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80046-9
更新日期:1981-07-01 00:00:00
abstract::Intrasinusoidal infiltration of bone marrow (BM) may accompany several malignant lymphoproliferative disorders. In small B-cell lymphomas, this pattern is considered specific for splenic marginal zone lymphoma (SMZL) when exclusive or prominent, although it may occur in other subtypes of non-Hodgkin's lymphomas (NHLs)...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(03)00286-7
更新日期:2003-08-01 00:00:00
abstract::Twelve cases of pure adenoid cystic carcinoma of the breast were reviewed. Patients ranged in age from 34 to 69 years. Seven carcinomas were in the right breast, and five in the left; five of the 12 were located in the central region of the breast, five in the upper outer quadrant, and the two in the upper inner and l...
journal_title:Human pathology
pub_type: 杂志文章,评审
doi:10.1016/s0046-8177(87)80413-6
更新日期:1987-12-01 00:00:00
abstract::We report a case of a newborn female with a rare tumor, a congenital sarcoma, presenting as an abdominal mass. Laparotomy demonstrated the tumor arising from the wall of the terminal ileum. Histologically, the tumor tissue was indistinguishable from clear cell sarcoma of the kidney and was composed of proliferating ce...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(93)90120-6
更新日期:1993-09-01 00:00:00
abstract::Twelve cases of bizarre parosteal osteochondromatous proliferation (BPOP), also known as Nora's lesion, are reported. Ten lesions were located in the small bones of the hands, and 2 were located in long bones (femur and proximal tibia). Patient age ranged from 12 to 63 years (average, 30.3 years). Radiography of the l...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1053/hupa.2002.130103
更新日期:2002-12-01 00:00:00
abstract::Natural killer (NK)/T-cell lymphomas represent a rare type of lymphoma derived from either activated NK cells or, rarely, cytotoxic T cells. These lesions are most commonly extranodal and tend to present as destructive lesions within the midline facial structures. Other than the nasal cavity and paranasal sinuses, sev...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2006.01.032
更新日期:2006-06-01 00:00:00
abstract::Congenital subclavian steal may result from various anomalies of the aortic arch. The most common predisposing type is the right aortic arch with an isolated left subclavian artery arising from a left ductus arteriosus. A rare variant includes isolation of the left common carotid as well as the left subclavian arterie...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(81)80200-6
更新日期:1981-10-01 00:00:00
abstract::Ground-glass hepatocytes are seen in chronic hepatitis B virus (HBV) infection and are known to harbor pre-S mutants, which are implicated in the pathogenesis of hepatocellular carcinoma (HCC). However, the association between ground-glass hepatocytes and HCC has yet to be clearly elucidated. The aim in the present st...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2013.01.020
更新日期:2013-08-01 00:00:00
abstract::SMARCA4-deficient thoracic sarcoma is a recently proposed new entity of soft tissue sarcomas with an undifferentiated round cell morphology that is diagnostically challenging. Here we report a case of this tumor where the diagnosis was established using limited samples and resources. A woman in her early 30s developed...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2017.05.024
更新日期:2017-12-01 00:00:00
abstract::We examined the infection of herpes simplex virus (HSV), human cytomegalovirus (HCMV), and Epstein-Barr virus (EBV) in 61 autopsy cases with secondary diffuse interstitial pneumonia (SDIP) by immunohistochemistry and compared our findings with those in 46 individuals without lung complications. There was no significan...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(94)90065-5
更新日期:1994-10-01 00:00:00
abstract::The distribution and amplification patterns of human papillomavirus were studied in 15 human papillomavirus (HPV) 16- and six HPV18-positive cervical carcinomas by colorimetric in situ hybridization (ISH). The findings were correlated with the viral copy number and status of E1/E2 viral genes in the tumor DNA, as stud...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/0046-8177(95)90175-2
更新日期:1995-06-01 00:00:00
abstract::Telomerase, the enzyme that stabilizes telomere length, is reactivated with almost all cancer types, and it may be necessary for unlimited cell proliferation. Assessment of malignancy in ordinary meningiomas is inconclusive because no clear-cut correlation exists between aggressive clinical behavior and histological f...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/s0046-8177(97)90029-0
更新日期:1997-04-01 00:00:00
abstract::It remains unclear why Barrett esophagus (BE)-associated adenocarcinoma (EAC) frequently occurs in the 0 to 3 o'clock area of the BE. The aims of this study were to clarify the localization of specialized intestinal metaplasia (SIM) as a precancerous lesion and of molecular alterations among different locations using ...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2015.12.013
更新日期:2016-05-01 00:00:00
abstract::Merkel cell polyomavirus is of oncogenic significance in approximately 80% of Merkel cell carcinomas. Morphological subcategories of the tumor differ in regard to viral status, the rare combined type being uniformly virus negative and the predominant pure type being mainly virus positive. Indications that different bi...
journal_title:Human pathology
pub_type: 杂志文章
doi:10.1016/j.humpath.2015.05.008
更新日期:2015-09-01 00:00:00