Type II ground-glass hepatocytes as a marker of hepatocellular carcinoma in chronic hepatitis B.

abstract：:Increasing differentiation in the human endometrium is associated with an apparent decrease in intercellular contacts between endometrial stromal cells ...

journal_title：Human pathology

authors： Parmley TH,Roberts DK,Emsa NJ,Horbelt DV

更新日期：1990-10-01 00:00:00

abstract：:We developed a procedure based on computerized image analysis to establish objective criteria for the differential diagnosis between mesothelial hyperplasia and cancer in peritoneal tissue samples obtained at second-look operations for ovarian cancer. The tumor tissue after chemotherapy was classified as "nonresponsiv...

journal_title：Human pathology

authors： Deligdisch L,Kerner H,Cohen CJ,Dargent D,Gil J

更新日期：1993-02-01 00:00:00

abstract：:Despite the nearly ubiquitous expression of telomerase in almost all types of malignant human tumors, studies have shown widely varying positivity in the highest-grade glioma, the glioblastomas (GBMs), ranging from 26% to 100% of tumors analyzed. We have previously shown significant variability in positive versus nega...

journal_title：Human pathology

authors： Kleinschmidt-Demasters BK,Evans LC,Bobak JB,Lopez-Uribe D,Hopper D,Shroyer AL,Shroyer KR

更新日期：2000-08-01 00:00:00

abstract：:A case of hemangiopericytoma arising in the esophagus is described. The light microscopic features were typical, and ultrastructural examination confirmed the presence of pericyte-like cells and excluded smooth muscle and fibroblastic differentiation. Areas of necrosis and a focus of mitotic activity within the tumor ...

journal_title：Human pathology

authors： Burke JS,Ranchod M

更新日期：1981-01-01 00:00:00

abstract：:Focal adhesion kinase (FAK) is one of the central signaling molecules found at focal adhesion sites, which are specific areas on the cell membrane where cells attach to extracellular matrix proteins. Focal adhesion kinase interacts with multiple signaling and adaptor molecules and effects several signaling pathways. O...

journal_title：Human pathology

authors： Madan R,Smolkin MB,Cocker R,Fayyad R,Oktay MH

更新日期：2006-01-01 00:00:00

abstract：:Basal cell proliferation is a common finding in a benign hyperplastic prostate gland. Occasionally, basal cell hyperplasia is so florid that it can be mistaken for prostatic adenocarcinoma. We characterized histological, ultrastructural, and immunohistochemical features of florid basal cell hyperplasia from transureth...

journal_title：Human pathology

authors： Yang XJ,Tretiakova MS,Sengupta E,Gong C,Jiang Z

更新日期：2003-05-01 00:00:00

abstract：:Giant cell tumor of tendon sheath (GCTTS) is a common soft tissue tumor. Immunophenotypical evidence suggests it is of synovial cell origin. There is controversy regarding the underlying nature of this lesion, specifically whether it is a neoplastic or nonneoplastic (ie, reactive or hyperplastic) process. Karyotypic a...

journal_title：Human pathology

authors： Vogrincic GS,O'Connell JX,Gilks CB

更新日期：1997-07-01 00:00:00

abstract：:Disruptions of the p16-CDK4/cyclin D1-pRb pathway (RB pathway) and the p14ARF-MDM2-p53 pathway (p53 pathway) are important mechanisms in the development of human malignancies. In this study, we investigated RB and p53 pathways in 46 epithelial ovarian cancers (EOCs). In the RB pathway, 16 (34.8%) of 46 cases had p16 g...

journal_title：Human pathology

authors： Hashiguchi Y,Tsuda H,Yamamoto K,Inoue T,Ishiko O,Ogita S

更新日期：2001-09-01 00:00:00

abstract：:We report the case of an exuberant ulcerative angiomatoid nasal lesion in a cocaine abuser. The lesion was made up of polymorphous endothelial cells with occasional mitoses, arranged in a lobular pattern with infiltrative-looking areas. There were extensive areas of thrombosis with focal recanalization. Intravascular ...

journal_title：Human pathology

authors： Alameda F,Fontane J,Corominas JM,Lloreta J,Serrano S

更新日期：2000-02-01 00:00:00

abstract：:Breast cancer is one of the common malignant diseases among women in Japan as well as in western countries, and its incidence continues to increase. Normal mammary duct epithelial cells exhibit a well-organized apicobasal polarity, which forms the basis for their specific structure and function. Although the loss of e...

journal_title：Human pathology

authors： Kojima Y,Akimoto K,Nagashima Y,Ishiguro H,Shirai S,Chishima T,Ichikawa Y,Ishikawa T,Sasaki T,Kubota Y,Inayama Y,Aoki I,Ohno S,Shimada H

更新日期：2008-06-01 00:00:00

abstract：:The pathology of cytomegalovirus (CMV) encephalitis was studied at autopsy in thirty patients with acquired immunodeficiency syndrome. Lesions could be segregated into five major categories: microglial nodules, isolated inclusion-bearing cells, focal parenchymal necrosis, necrotizing ventriculo-encephalitis, and necro...

journal_title：Human pathology

authors： Morgello S,Cho ES,Nielsen S,Devinsky O,Petito CK

更新日期：1987-03-01 00:00:00

abstract：:T3 renal cell carcinoma (RCC) is a heterogeneous group of tumors that are substaged based on perirenal or sinus fat invasion, adrenal invasion, and renal vein invasion. To evaluate whether the extent of fat invasion (minimal versus extensive) and direct adrenal gland invasion, renal vein invasion with or without concu...

journal_title：Human pathology

authors： Jung SJ,Ro JY,Truong LD,Ayala AG,Shen SS

更新日期：2008-11-01 00:00:00

abstract：:Microsatellite instability (MSI) defines a specific type of genetic instability. Although consensus diagnostic criteria for MSI definition in colorectal cancer have been established, their utility in other tumor types remain to be proven. Previously we developed a mathematical model for MSI definition in colorectal ca...

journal_title：Human pathology

authors： Musulén E,Moreno V,Reyes G,Sancho FJ,Peinado MA,Esteller M,Herman JG,Combalia N,Rey M,Capellá G

更新日期：2004-03-01 00:00:00

abstract：:Sinonasal undifferentiated carcinoma (SNUC) is an aggressive malignancy with a poor prognosis, and pathologically, it is a diagnosis of exclusion. Rendering this diagnosis can be challenging in practice because of the large number of diverse entities in the differential diagnosis. We encountered an index case of a sin...

journal_title：Human pathology

authors： Baraban E,Tong CCL,Adappa ND,Cooper K

更新日期：2020-07-01 00:00:00

abstract：:Aberrant crypt foci (ACF) are one of the earliest putative preneoplastic, and in some cases, neoplastic lesions in human colons. These microscopic lesions, identified on methylene blue-stained mucosa with a low-power-magnification microscope, are thought to be closely related to the earliest steps in multistage coloni...

journal_title：Human pathology

authors： Shpitz B,Bomstein Y,Mekori Y,Cohen R,Kaufman Z,Neufeld D,Galkin M,Bernheim J

更新日期：1998-05-01 00:00:00

abstract：:Four cases of clear cell lymphoma were studied by means of light and electron microscopy, enzyme-histochemistry, and E- and EAC-rosette formation. On light microscopic examination the tumors were seen to be composed mainly of round, oval, or slight irregular cells with water-clear, abundant cytoplasm. The neoplastic c...

journal_title：Human pathology

authors： Zhuang HG,Liang GZ,Li WC,Zhang YQ,Guo RZ,Liu SL,He NX

更新日期：1988-07-01 00:00:00

abstract：:Primary colorectal diffuse large B-cell lymphoma (DLBCL) is rare, and its clinicopathological and genetic features are poorly understood. The aim of our study was to elucidate the frequency and prognostic significance of molecular subgroups in colorectal DLBCL. We examined 25 cases of colorectal lymphoma with DLBCL-li...

journal_title：Human pathology

authors： Hori Y,Yamamoto H,Nozaki Y,Torisu T,Fujiwara M,Taguchi K,Nishiyama K,Nakamura S,Kitazono T,Oda Y

更新日期：2020-02-01 00:00:00

abstract：:Germ cell tumors arising within the central nervous system are rare neoplasms that typically occur along midline structures in children and young adults. Although isochromosome 12p is established as a frequent chromosomal abnormality in testicular germ cell tumors, studies examining isochromosome 12p in primary centra...

journal_title：Human pathology

authors： Sukov WR,Cheville JC,Giannini C,Carlson AW,Shearer BM,Sinnwell JP,Ketterling RP

更新日期：2010-02-01 00:00:00

abstract：:Two extraskeletal myxoid chondrosarcomas were examined by electron microscopy. In addition to the well-described ultrastructural features indicative of chondroblastic origin, both of these chondrosarcomas had unusual parallel microtubules packed within rough endoplasmic reticulum. This paper reviews the differential d...

journal_title：Human pathology

authors： DeBlois G,Wang S,Kay S

更新日期：1986-05-01 00:00:00

abstract：:Activating transcription factor 3, a member of the activating transcription factor/cyclic adenosine monophosphate response element-binding family of transcription factors, is an adaptive response gene that plays an oncogenic role in the development of various cancers. To our knowledge, few information are available on...

journal_title：Human pathology

authors： Kim MS,In SG,Park OJ,Won CH,Lee MW,Choi JH,Kim CW,Kim SE,Moon KC,Chang S

更新日期：2011-07-01 00:00:00

abstract：:The authors present 11 cases of plexiform neurofibroma (PN) that featured a very characteristic type of cell appearing as multivacuolated mucin-filled cells (MMFC). The 11 cases were obtained after reviewing 109 cases of PN. Six out of 10 patients showed clinical features of neurofibromatosis type 1. The size of PN ra...

journal_title：Human pathology

authors： Michal M,Kazakov DV,Hadravský L,Michalová K,Rychlý B,Michal M

更新日期：2017-02-01 00:00:00

abstract：:Although the histopathologic patterns associated with Helicobacter pylori infection have been described, details of the interaction between bacteria, epithelial cells, and inflammatory cells remain elusive. One of the limiting factors has been the lack of a staining technique that allows the simultaneous visualization...

journal_title：Human pathology

authors： Genta RM,Robason GO,Graham DY

更新日期：1994-03-01 00:00:00

abstract：:Plasmacytoid dendritic cells, which play a fundamental role in the innate immune response, are best known for their presence in hyaline-vascular Castleman disease and histiocytic necrotizing lymphadenitis. The relative number and distribution in many reactive entities as detected using more sensitive methods are uncer...

journal_title：Human pathology

authors： Rollins-Raval MA,Marafioti T,Swerdlow SH,Roth CG

更新日期：2013-06-01 00:00:00

abstract：:Ciliated metaplasia (CM) of gastric mucosa is common in Japanese individuals but rare in whites. We studied 36 consecutive gastrectomies from Chinese individuals for the presence of CM. The gastrectomies were performed for adenocarcinoma (n = 22), benign ulcer (n = 13), and malignant lymphoma (n = 1). Ciliated metapla...

journal_title：Human pathology

authors： Chan WY,Hui PK,Leung KM,Robertson CS,Chung SC

更新日期：1993-10-01 00:00:00

abstract：:We examined the infection of herpes simplex virus (HSV), human cytomegalovirus (HCMV), and Epstein-Barr virus (EBV) in 61 autopsy cases with secondary diffuse interstitial pneumonia (SDIP) by immunohistochemistry and compared our findings with those in 46 individuals without lung complications. There was no significan...

journal_title：Human pathology

authors： Oda Y,Okada Y,Katsuda S,Nakanishi I

更新日期：1994-10-01 00:00:00

abstract：:Fifty-three pure mucinous carcinomas of breast were studied, with long-term follow-up evaluation (average, 15 years) for 37. The mean age of the patients was 63 years. Long-term survival (Kaplan-Meier method) was 68 per cent, excluding non-tumor-related deaths. Median survival for the patients with fatal carcinomas wa...

journal_title：Human pathology

authors： Clayton F

更新日期：1986-01-01 00:00:00

abstract：:We report a tumor arising in the middle ear of a 65-year-old female patient that was composed of an ovarian-type stroma (OS) and an epithelial component. The tumor consisted of irregular, polypoid masses containing multiple variably sized cystic spaces, which were invariably surrounded by the OS. The cystic spaces wer...

journal_title：Human pathology

authors： Michal M,Skálová A,Kazakov DV,Pecková K,Heidenreich F,Grossmann P,Michal M

更新日期：2017-03-01 00:00:00

abstract：:Pediatric follicular lymphoma (pFL) is a rare neoplasm with features differing from follicular lymphoma arising in adults. Here, we describe a rare case of pFL that showed morphologic features partially overlapping with progressive transformation of germinal centers and reactive follicular hyperplasia. As typical of p...

journal_title：Human pathology

authors： Karnik T,Ozawa MG,Lefterova M,Luna-Fineman S,Alvarez E,Link M,Zehnder JL,Arber DA,Ohgami RS

更新日期：2015-04-01 00:00:00

abstract：:Adenoid cystic carcinoma (ACC) is a common salivary gland neoplasm with a lengthy clinical course and often late local recurrences after surgical resection. This is accounted for histologically by its infiltrative capacity and distinct propensity for perineural invasion. The expression of biological markers may help e...

journal_title：Human pathology

authors： Kowalski PJ,Paulino AF

更新日期：2002-09-01 00:00:00

abstract：:Paraffin-embedded sections of 99 human adrenal and extraadrenal paragangliomas were analyzed by the indirect immunoperoxidase technique for the presence of neuron-specific enolase (NSE) and 10 neuropeptides. Each showed diffuse staining for NSE. Most tumors were positive for [Leu5]-enkephalin (76 per cent), [Met5]-enk...

journal_title：Human pathology

authors： Linnoila RI,Lack EE,Steinberg SM,Keiser HR

更新日期：1988-01-01 00:00:00