Intercellular contacts between stromal cells in the normal human endometrium throughout the menstrual cycle.

abstract：:The presence of positive surgical margins is a negative prognostic indicator in patients undergoing prostatectomy for prostate cancer; whether the extent of the positive margins affects the clinical outcome with regards to prostate-specific antigen (PSA) recurrence remains uncertain. We evaluated the linear extent of ...

journal_title：Human pathology

authors： Marks RA,Koch MO,Lopez-Beltran A,Montironi R,Juliar BE,Cheng L

更新日期：2007-08-01 00:00:00

abstract：:Primary small bowel adenocarcinoma is rare. Although generally similar to colonic adenocarcinoma, some small bowel adenocarcinomas exhibit unique morphologic features, particularly those arising in association with Crohn disease. In this study, 15 sporadic small bowel adenocarcinomas and 11 Crohn enteritis-associated ...

journal_title：Human pathology

authors： Whitcomb E,Liu X,Xiao SY

更新日期：2014-02-01 00:00:00

abstract：:Fourteen chordomas, five myxoid chondrosarcomas, and 15 chondroid tumors (four mesenchymal and 11 conventional chondrosarcomas) were stained for cytokeratin, S-100 protein, carcinoembryonic antigen (CEA), and vimentin. The epithelial markers stained 93 per cent of the chordomas, whereas none of the tumors of other typ...

journal_title：Human pathology

authors： Abenoza P,Sibley RK

更新日期：1986-07-01 00:00:00

abstract：:The precise regulation and maintenance of balance between cell proliferation and cell death in multicellular organisms is critical for tissue homeostasis. bcl-2 initiates a new gene family involved in the regulation of cell death and survival without affecting cell proliferation. Expression of Bcl-2 has been reported ...

journal_title：Human pathology

authors： Lu QL,Abel P,Foster CS,Lalani EN

更新日期：1996-02-01 00:00:00

abstract：:The distribution and amplification patterns of human papillomavirus were studied in 15 human papillomavirus (HPV) 16- and six HPV18-positive cervical carcinomas by colorimetric in situ hybridization (ISH). The findings were correlated with the viral copy number and status of E1/E2 viral genes in the tumor DNA, as stud...

journal_title：Human pathology

authors： Berumen J,Unger ER,Casas L,Figueroa P

更新日期：1995-06-01 00:00:00

abstract：:An immunohistochemical survey of X-linked inhibitor of apoptosis (XIAP) expression in mammary carcinoma was performed. XIAP, the most potent of the inhibitor of apoptosis family of caspase inhibitors, has been linked to tumor aggressiveness and therapeutic resistance in several malignancies and is considered an attrac...

journal_title：Human pathology

authors： Jaffer S,Orta L,Sunkara S,Sabo E,Burstein DE

更新日期：2007-06-01 00:00:00

abstract：:Most esophageal intraepithelial lymphocytes (IELs) express T-cell markers. Increased numbers of esophageal IELs have been shown in reflux esophagitis. The cytotoxic potential and activity of esophageal IELs have not as yet been examined. Our objectives were to determine whether esophageal IELs express the recently des...

journal_title：Human pathology

authors： Resnick MB,Finkelstein Y,Weissler A,Levy J,Yakirevich E

更新日期：1999-04-01 00:00:00

abstract：:Women with breast cancer have an increased risk of developing primary ovarian tumors. Because a differential diagnosis between primary and metastatic tumors may be difficult in poorly differentiated ovarian neoplasms, breast carcinoma markers may be helpful in establishing the primary site of origin. Gross cystic dise...

journal_title：Human pathology

authors： Monteagudo C,Merino MJ,LaPorte N,Neumann RD

更新日期：1991-04-01 00:00:00

abstract：:Except for post-transfusion hepatitis (PTH), the transmission of disease by blood transfusion appears to be very limited. There are only a few case reports documenting the transmission of malaria and other parasitic diseases, syphilis, or bacterial infections. The ability to eradicate PTH will depend on the developmen...

journal_title：Human pathology

authors： Kahn RA

更新日期：1983-03-01 00:00:00

abstract：:Malignant peripheral nerve sheath tumor is a malignant tumor showing nerve sheath differentiation. Approximately one-half of malignant peripheral nerve sheath tumors arise from a benign peripheral nerve sheath tumor, which is commonly a neurofibroma in patients with neurofibromatosis type 1. Malignant peripheral nerve...

journal_title：Human pathology

authors： Endo M,Yamamoto H,Harimaya K,Kohashi K,Ishii T,Setsu N,Iwamoto Y,Oda Y

更新日期：2013-12-01 00:00:00

abstract：:Adamantinoma of the long bones is a rare, typically low-grade malignant tumor that frequently involves the tibia. Radiographically, adamantinoma is characteristically a lytic, intracortical, and expansile lesion with variable margins. Histologically, adamantinoma is a bimorphic neoplasm, composed of epithelial and ost...

journal_title：Human pathology

authors： Dashti NK,Howe BM,Inwards CY,Fritchie KJ,Carter JM

更新日期：2019-09-01 00:00:00

abstract：:Endometrioid endometrial carcinomas (EECs) are correlated with high serum levels of androgens and estrogen. We hypothesized that Leydig cells and ovarian stromal hyperplasia contribute to postmenopausal ovarian androgen production and are observed more frequently in EEC patients. Ovaries of postmenopausal women with E...

journal_title：Human pathology

authors： Reijnen C,Küsters-Vandevelde HVN,Abbink K,Zusterzeel PLM,van Herwaarden AE,van der Laak JAWM,Massuger LFAG,Snijders MPLM,Pijnenborg JMA,Bulten J

更新日期：2019-03-01 00:00:00

abstract：:A case of xanthomatosis of the small bowel is described. Beginning with the proximal jejunum, an 85-cm segment of small bowel was distorted by regularly spaced nodular accumulations of lipid-laden macrophages that expanded the submucosa and muscularis and extended to the serosal surface. The conditions often associate...

journal_title：Human pathology

authors： Coletta U,Sturgill BC

更新日期：1985-04-01 00:00:00

abstract：:The relationship between nuclear diameter and biologic behavior was studied in 127 cases of thyroid carcinoma. Using a sonic digitizer coupled to a minicomputer, nuclear diameters of 200 randomly selected cancer cells from each case (hematoxylineosin-stained paraffin sections) projected at X 400 magnification were tra...

journal_title：Human pathology

authors： Lee TK,Myers RT,Bond MG,Marshall RB,Kardon B

更新日期：1987-12-01 00:00:00

abstract：:Glial tumors of the retina are rare. Most are syndrome associated and include pilocytic astrocytoma in neurofibromatosis type 1 and subependymal giant cell astrocytoma in tuberous sclerosis complex. Acquired, more conventional, diffuse astrocytomas are less frequent. Ependymoma is exquisitely rare. Herein, we report t...

journal_title：Human pathology

authors： Tay A,Scheithauer BW,Cameron JD,Myhre MJ,Boerner MJ

更新日期：2009-04-01 00:00:00

abstract：:Epithelial-mesenchymal transition (EMT) plays a pivotal role in tumor invasion and metastasis in various malignancies. ZEB2/SIP1 is an important EMT regulator and down-regulates E-cadherin expression. The present study was planned to explore status of EMT-associated markers ZEB2/SIP1 and E-cadherin in eyelid sebaceous...

journal_title：Human pathology

authors： Bhardwaj M,Sen S,Sharma A,Kashyap S,Chosdol K,Pushker N,Bajaj MS,Bakhshi S

更新日期：2015-10-01 00:00:00

abstract：:A series of 36 cases of chondromyxoid fibroma (CMF) of bone, a rare benign tumor that may be confused with chondrosarcoma, is presented to aid in correctly identifying and diagnosing these neoplasms. In this series, CMFs were found in patients of all age groups, with no predominance between sexes. Long bone tumors wer...

journal_title：Human pathology

authors： Zillmer DA,Dorfman HD

更新日期：1989-10-01 00:00:00

abstract：:Bone Marrow Transplant (BMT) is a critical therapeutic intervention for a variety of diseases occurring in the pediatric patient. Complications of allogeneic BMT include graft-versus-host disease (GVHD), infection, drug toxicity, thrombotic microangiopathy, and veno-occlusive disease. With solid organ transplantation,...

journal_title：Human pathology

authors： Selby DM,Rudzki JR,Bayever ES,Chandra RS

更新日期：1999-07-01 00:00:00

abstract：:This presentation reports the light and electron microscopic findings relating to the vascular and glomerular changes in the kidney in a series of 25 patients having malignant hypertension, the hemolytic-uremic syndrome, scleroderma, or toxemia of pregnancy. The pathologic changes were generally similar in each of the...

journal_title：Human pathology

authors： Sinclair RA,Antonovych TT,Mostofi FK

更新日期：1976-09-01 00:00:00

abstract：:Human papilloma virus (HPV) has emerged as the key etiologic driver in the majority of cancers at head and neck mucosal sites. First described in the uterine cervix and subsequently in oropharyngeal squamous cell carcinomas, the morphologic and clinical spectrum of HPV-related neoplasia has continued to expand and now...

journal_title：Human pathology

authors： Devins KM,Tetzlaff MT,Baloch Z,LiVolsi VA

更新日期：2019-12-01 00:00:00

abstract：:Carbonic anhydrase IX (CA9) is reportedly overexpressed in several types of carcinomas, but little is known about the expression pattern of CA9 in oral cavity cancer and the corresponding normal tissues. We aimed to assess the prevalence of CA9 expression and its prognostic implications in patients with oral cavity sq...

journal_title：Human pathology

authors： Choi SW,Kim JY,Park JY,Cha IH,Kim J,Lee S

更新日期：2008-09-01 00:00:00

abstract：:Molecular apocrine breast cancer (MABC) is a molecular subtype with a poor prognosis, and there is urgent need to find new therapeutic targets. Epidermal growth factor receptor (EGFR) plays an important part in regulating the biological behavior of tumor cells, and EGFR-targeted drugs have already been used in therapy...

journal_title：Human pathology

authors： Liu X,Feng C,Liu J,Liu J,Li C,Xu C,Niu Y

更新日期：2018-07-01 00:00:00

abstract：:We reviewed open lung biopsies from 35 patients with Wegener's (pathergic) granulomatosis in order to study the histogenesis of the pulmonary lesions and to identify the early lesions. The process of pathergic necrosis is fundamental in the production of extravascular and vascular lesions and was divided into micronec...

journal_title：Human pathology

authors： Mark EJ,Matsubara O,Tan-Liu NS,Fienberg R

更新日期：1988-09-01 00:00:00

abstract：:The aim of the current study was to test whether the grade group assessed in the index tumor nodule predicts biochemical recurrence after surgery. The study cohort series included 144 consecutive patients treated by laparoscopic radical prostatectomy. The following parameters were evaluated in each case: type of radic...

journal_title：Human pathology

authors： Vau N,Henriques V,Cheng L,Blanca A,Fonseca J,Montironi R,Cimadamore A,Lopez-Beltran A

更新日期：2019-11-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is the most common oral cancer, and major efforts is being made to identify molecular markers capable to differentiate oral potentially malignant lesions (OPMLs) with indolent course from lesions with aggressive behavior. We undertook a study to evaluate if gain of the human telomer...

journal_title：Human pathology

authors： Dorji T,Monti V,Fellegara G,Gabba S,Grazioli V,Repetti E,Marcialis C,Peluso S,Di Ruzza D,Neri F,Foschini MP

更新日期：2015-09-01 00:00:00

abstract：:Focal adhesion kinase (FAK) is one of the central signaling molecules found at focal adhesion sites, which are specific areas on the cell membrane where cells attach to extracellular matrix proteins. Focal adhesion kinase interacts with multiple signaling and adaptor molecules and effects several signaling pathways. O...

journal_title：Human pathology

authors： Madan R,Smolkin MB,Cocker R,Fayyad R,Oktay MH

更新日期：2006-01-01 00:00:00

abstract：:Invasive squamous cell carcinoma (SCC) of the cervix involves the progression of premalignant cervical intraepithelial neoplasia (CIN) and is associated with persistent human papillomavirus infection. Most CINs will regress, and the challenge is to identify the lesions likely to progress to invasive cancer. We evaluat...

journal_title：Human pathology

authors： Velez-Perez A,Wang XI,Li M,Zhang S

更新日期：2017-01-01 00:00:00

abstract：:We investigated the use of remote video microscopy (telepathology) to assist in the diagnosis of 52 neurosurgical frozen section cases. The TelMed system (Discovery Medical Systems, Overland Park, KS), in which the referring pathologist selects appropriate fields for transmission to the consultant, was used for the st...

journal_title：Human pathology

authors： Becker RL Jr,Specht CS,Jones R,Rueda-Pedraza ME,O'Leary TJ

更新日期：1993-08-01 00:00:00

abstract：:SPARC (secreted protein acidic and rich in cysteine, also called osteonectin, BM-40, and 43K protein) is a matricellular protein and is associated with cell-matrix interactions during cell proliferation and extracellular remodeling. It is also implicated in the neovascularization, invasion, and metastasis of human mal...

journal_title：Human pathology

authors： Sakai N,Baba M,Nagasima Y,Kato Y,Hirai K,Kondo K,Kobayashi K,Yoshida M,Kaneko S,Kishida T,Kawakami S,Hosaka M,Inayama Y,Yao M

更新日期：2001-10-01 00:00:00

abstract：:A 75 year old man presented with metastatic carcinoma of the brain. At autopsy a primary scar adenocarcinoma of the lung was found. By light microscopy the cytoplasm of the tumor cells was seen to contain hyalin masses with tinctorial properties identical to those of the Mallory bodies seen in human alcoholic liver di...

journal_title：Human pathology

authors： Michel RP,Limacher JJ,Kimoff RJ

更新日期：1982-01-01 00:00:00