Value of gross cystic disease fluid protein-15 in distinguishing metastatic breast carcinomas among poorly differentiated neoplasms involving the ovary.

abstract：:Malignant gastrointestinal neuroectodermal tumor (MGNET) is a very rare, aggressive malignant neoplasm that may occur in any location in the gastrointestinal tract. Malignant gastrointestinal neuroectodermal tumors typically consist of sheet-like to pseudopapillary proliferation of primitive-appearing epithelioid cell...

journal_title：Human pathology

authors： Boland JM,Folpe AL

更新日期：2016-11-01 00:00:00

abstract：:Giant cell tumor of tendon sheath (GCTTS) is a common soft tissue tumor. Immunophenotypical evidence suggests it is of synovial cell origin. There is controversy regarding the underlying nature of this lesion, specifically whether it is a neoplastic or nonneoplastic (ie, reactive or hyperplastic) process. Karyotypic a...

journal_title：Human pathology

authors： Vogrincic GS,O'Connell JX,Gilks CB

更新日期：1997-07-01 00:00:00

abstract：:Brain metastases (BMs) are common complications of adenocarcinomas (ADCs) of the lung and are associated with a poor prognosis. Although an increasing amount of data indicates that dysregulated activity of mammalian target of rapamycin (mTOR) can influence the metastatic potential of various tumors, the role of mTOR c...

journal_title：Human pathology

authors： Krencz I,Sebestyén A,Fábián K,Márk Á,Moldvay J,Khoor A,Kopper L,Pápay J

更新日期：2017-04-01 00:00:00

abstract：:Urethral caruncle is a benign polypoid mass of the urethral meatus in primarily postmenopausal women. Although a conclusive association with malignancy, urologic disorder, or systemic disease has not been established, often the lesion carries a challenging clinical differential diagnosis that includes malignancy. Conv...

journal_title：Human pathology

authors： Conces MR,Williamson SR,Montironi R,Lopez-Beltran A,Scarpelli M,Cheng L

更新日期：2012-09-01 00:00:00

abstract：:We describe a method for the immunocytochemical assessment of estrogen receptor (ER) status on routinely processed, formalin-fixed tissue using a recently developed commercially available monoclonal antibody (Dako 1D5) with a microwave antigen retrieval technique. A series of 90 cases of human breast carcinoma was ana...

journal_title：Human pathology

authors： Goulding H,Pinder S,Cannon P,Pearson D,Nicholson R,Snead D,Bell J,Elston CW,Robertson JF,Blamey RW

更新日期：1995-03-01 00:00:00

abstract：:PELP1 is a novel coregulator of nuclear hormone receptors and is implicated in playing a role in driving breast cancer and enhancing metastatic potential. The PELP1 protein expression and potential role of PELP1 in triple-negative breast carcinoma (TNBC) have not been well characterized. We investigated PELP1 expressi...

journal_title：Human pathology

authors： Dang DN,Raj G,Sarode V,Molberg KH,Vadlamudi RK,Peng Y

更新日期：2015-12-01 00:00:00

abstract：:The pathogenesis of lacaziosis continues to be obscure, and works have investigated the blood systemic immune response or the dermal immune response in restricted lesions in different body regions. Some authors describe that the inflammatory infiltrate in lacaziosis lesions showed a predominance of macrophages followe...

journal_title：Human pathology

authors： Oliveira Carneiro FR,da Cunha Fischer TR,Brandão CM,Pagliari C,Duarte MI,Quaresma JA

更新日期：2015-02-01 00:00:00

abstract：:Clinicopathologic records and neuropathologic tissues of 109 patients who underwent necropsy after treatment with bone marrow transplantation (BMT) were examined. Underlying disorders included leukemia (70), aplastic anemia (25), solid tumors (7), lymphoma (5), Hodgkin's disease (1) and Wiskott-Aldrich syndrome (1). T...

journal_title：Human pathology

authors： Mohrmann RL,Mah V,Vinters HV

更新日期：1990-06-01 00:00:00

abstract：:Patients with small cell lung carcinoma (SCLC) rarely demonstrate long-term survival. We previously reported that gene expression profiling identified a subset of SCLC with good prognosis in surgical cases. To find an easier way to routinely identify SCLC belonging to this subset, we conducted the present study with a...

journal_title：Human pathology

authors： Hamanaka W,Motoi N,Ishikawa S,Ushijima M,Inamura K,Hatano S,Uehara H,Okumura S,Nakagawa K,Nishio M,Horai T,Aburatani H,Matsuura M,Iwasaki A,Ishikawa Y

更新日期：2014-05-01 00:00:00

abstract：:Benign lymphocytic angiitis and granulomatosis is a T-cell lymphoproliferative disorder confined to the lung and corresponding to a low-grade angiocentric immunoproliferative lesion. Controversy remains as to whether these lesions are lymphomas. We report such a case in an 8-year-old patient with Burkitt's lymphoma in...

journal_title：Human pathology

authors： Vergier B,Capron F,Trojani M,Labouyrie E,Ferrer J,Eghbali H,Merlio JP,de Mascarel A

更新日期：1992-10-01 00:00:00

abstract：:Thrombosis of large fetal vessels in the placenta leads to regions of downstream avascular villi (AV). Avascular villi have been associated with adverse outcomes in anecdotal reports, but no controlled study of their significance has been done. We prospectively gathered cases of extensive AV (n = 29) occurring over a ...

journal_title：Human pathology

authors： Redline RW,Pappin A

更新日期：1995-01-01 00:00:00

abstract：:Secretory carcinoma (SC) of the salivary gland is a low-grade malignancy associated with a well-defined clinical, histologic, immunohistochemical, and cytogenetic signature. Although the t(12;15) (p13;q25) translocation resulting in an ETV6-NTRK3 gene fusion is well documented, advances in molecular profiling in saliv...

journal_title：Human pathology

authors： Guilmette J,Dias-Santagata D,Nosé V,Lennerz JK,Sadow PM

更新日期：2019-01-01 00:00:00

abstract：:Cervical intraepithelial neoplasia (CIN) is historically viewed as a progressive biologic continuum leading to cervical cancer. However, it has been questioned whether CIN1 lesions ever progress. To this end, we evaluated the number of patients with a CIN3 and a previous CIN1 diagnosis. Subsequently, metachronous CIN1...

journal_title：Human pathology

authors： Litjens RJ,Van de Vijver KK,Hopman AH,Ummelen MI,Speel EJ,Sastrowijoto SH,Van Gorp T,Slangen BF,Kruitwagen RF,Krüse AJ

更新日期：2014-02-01 00:00:00

abstract：:Thirty cases of ductal carcinoma in situ (DCIS) of the breast, showing histological microcalcifications, were studied to clarify their mechanism of formation. Undecalcified sections revealed three types of calcium precipitates: type I and II granular calcifications (GCs) and laminar calcifications (LCs). In type I GCs...

journal_title：Human pathology

authors： Foschini MP,Fornelli A,Peterse JL,Mignani S,Eusebi V

更新日期：1996-02-01 00:00:00

abstract：:After multiple fragmentation of neoplastic nuclei into "nucleotesimals," a recently discovered variety of amitosis, some fragments appear to be inflated to full nuclear size; other probably lyse, releasing nucleic acid, which may assist in the synthesis of new cytoplasm around newly formed nuclei. This observation may...

journal_title：Human pathology

authors： Elias H,Hyde DM

更新日期：1982-07-01 00:00:00

abstract：:Plasma cells are the hallmark of chronic endometritis but are not specific for upper tract infection. Plasma cells have also been noted in hormonally mediated endometrial disorders in association with gland architectural changes ("disordered proliferative" and "anovulatory" patterns), and stromal breakdown. We reviewe...

journal_title：Human pathology

authors： Gilmore H,Fleischhacker D,Hecht JL

更新日期：2007-04-01 00:00:00

abstract：:Mutually exclusive histone 3.3 gene mutations have been recognized in chondroblastoma and giant cell tumor of bone (GCTB), which may be useful for differential diagnostic purposes in morphologically ambiguous cases. Although more than 90% of GCTBs present histone 3.3 variants exclusively in the H3F3A gene, chondroblas...

journal_title：Human pathology

authors： Righi A,Mancini I,Gambarotti M,Picci P,Gamberi G,Marraccini C,Dei Tos AP,Simi L,Pinzani P,Franchi A

更新日期：2017-10-01 00:00:00

abstract：:Paget's disease is a skin cancer characterized by characteristic (Paget) cells scattered in the epidermis. Although its prognosis is generally favorable with surgical resection, the clinical outcome turns unfavorable in cases with recurrence and metastasis. Therefore, establishment of effective therapeutic regimens is...

journal_title：Human pathology

authors： Ogawa T,Nagashima Y,Wada H,Akimoto K,Chiba Y,Nagatani T,Inayama Y,Yao M,Aoki I,Ikezawa Z

更新日期：2005-12-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a commonly occurring tumor in southern China. Although several causative factors have now been recognized, the genetic basis underlying its tumorigenesis is still unclear. To identify potential chromosomal aberrations for further investigations, comparative genomic hybridization (CGH)...

journal_title：Human pathology

authors： Fan CS,Wong N,Leung SF,To KF,Lo KW,Lee SW,Mok TS,Johnson PJ,Huang DP

更新日期：2000-02-01 00:00:00

abstract：:A cytogenetic study of an eccrine spiradenoma and two lymph node metastases, with a growth pattern and microscopic appearance typical for benign eccrine spiradenoma, revealed a 46,XY-5,del(16)(q22),+mar(t(?;5)(?::5q13----5qter)) karyotype. The finding of the same abnormal karyotype in the tumor and the metastases sugg...

journal_title：Human pathology

authors： Dijkhuizen T,van den Berg E,Nikkels PG,Hoekstra HJ,de Jong B

更新日期：1992-09-01 00:00:00

abstract：:The shortage of pathologists is being created by a combination of three factors: inadequate trainee recruitment, high trainee attrition, and accelerating practitioner attrition. The current report provides comprehensive data on the first two factors. The third factor is, by every estimate, likely to become worse over ...

journal_title：Human pathology

authors： Vance RP,Prichard RW,Smith RD

更新日期：1991-11-01 00:00:00

abstract：:The Ewing family of tumors (EFT) is characterized by high MIC2/CD99 expression and specific EWS/ETS gene rearrangements, resulting in different chimeric transcripts. Further division into peripheral primitive neuroectodermal tumors and Ewing's sarcoma is still debated and, in the absence of distinct morphological para...

journal_title：Human pathology

authors： Amann G,Zoubek A,Salzer-Kuntschik M,Windhager R,Kovar H

更新日期：1999-09-01 00:00:00

abstract：:There is limited published data regarding the significance of the number or position of nucleoli and the presence of apoptotic bodies in diagnostically challenging cases of adenocarcinoma of the prostate on needle biopsy material. One hundred consecutive prostate cancers on needle biopsy were sent because of diagnosti...

journal_title：Human pathology

authors： Aydin H,Zhou M,Herawi M,Epstein JI

更新日期：2005-11-01 00:00:00

abstract：:Most esophageal intraepithelial lymphocytes (IELs) express T-cell markers. Increased numbers of esophageal IELs have been shown in reflux esophagitis. The cytotoxic potential and activity of esophageal IELs have not as yet been examined. Our objectives were to determine whether esophageal IELs express the recently des...

journal_title：Human pathology

authors： Resnick MB,Finkelstein Y,Weissler A,Levy J,Yakirevich E

更新日期：1999-04-01 00:00:00

abstract：:Botryomycosis is a rare bacterial infection of the skin and, rarely, viscera that is characterized by the formation of characteristic hyaline grains. We encountered a patient with Erysipelothrix rhusiopathiae endocarditis who developed visceral botryomycosis. He was a 54-year-old black man who presented in sepsis with...

journal_title：Human pathology

authors： Carson HJ,Perkins JT

更新日期：2005-01-01 00:00:00

abstract：:This article describes a case of lymphomatoid granulomatosis without active pulmonary involvement of stigmata of healed granulomatous lesions in the lungs. The patient had ischemic segmental colitis due to mesenteric arterial intimal fibrosis, which we interpreted as spontaneously regressed granulomatous involvement o...

journal_title：Human pathology

authors： Singh G,Hellstrom HR

更新日期：1978-05-01 00:00:00

abstract：:A 57 year old man presented with a two week history of right sided chest pain. An admission chest x-ray examination revealed a 2 by 1 cm. lytic lesion of the ninth right rib and right sided pleural effusion. The patient underwent a right thoracotomy during which 700 cc. of blood tinged pleural fluid was drained and a ...

journal_title：Human pathology

authors： Pappas CA,Rheinlander HF,Stadecker MJ

更新日期：1980-11-01 00:00:00

abstract：:Encapsulated thyroid tumors of follicular cell origin with high-grade features (EFHG) are unusual neoplasms. In current classification schemes, they are called atypical adenomas or follicular, papillary, or poorly differentiated carcinoma. When noninvasive, EFHG create a major therapeutic/diagnostic dilemma stemming f...

journal_title：Human pathology

authors： Rivera M,Ricarte-Filho J,Patel S,Tuttle M,Shaha A,Shah JP,Fagin JA,Ghossein RA

更新日期：2010-02-01 00:00:00

abstract：:Plakophilins (PKPs) are a set of 3 constitutive armadillo repeat proteins of the desmosomal plaque, termed PKP 1, PKP 2, and PKP 3, which have been shown to be functionally relevant for desmosomal adhesion. We have performed a systematic immunohistochemical study of the 3 PKPs in oral and pharyngeal squamous cell carc...

journal_title：Human pathology

authors： Schwarz J,Ayim A,Schmidt A,Jäger S,Koch S,Baumann R,Dünne AA,Moll R

更新日期：2006-05-01 00:00:00

abstract：:Trefoil factors are wound-healing peptides important in protection and healing of the human gastrointestinal tract. Their potential for therapy of gastrointestinal ulcers has been established. This study investigated the hypothesis that trefoil factors are also present in human salivary gland. Tissues from surgical bi...

journal_title：Human pathology

authors： Devine DA,High AS,Owen PJ,Poulsom R,Bonass WA

更新日期：2000-04-01 00:00:00