Pathology trainee manpower: APC program directors' questionnaire, 1989 results.

Abstract:

:The shortage of pathologists is being created by a combination of three factors: inadequate trainee recruitment, high trainee attrition, and accelerating practitioner attrition. The current report provides comprehensive data on the first two factors. The third factor is, by every estimate, likely to become worse over the decade beginning in 1988. Demographics show that greater numbers of pathologists will be reaching retirement age every year. The trainee attrition problem appears to be very serious, and we currently do not have data on why residents leave pathology training, when they leave, or where they go (ie, to what other specialties, etc). Future APC program directors' questionnaires must address these issues. Yet, we must also solve a serious problem in recruitment. Currently, about 35% to 38% of all first-year pathology residents decide to enter pathology only after entering residency programs in other specialties with the intent to remain in that specialty. Therefore, we need to recognize both the problem of inadequate recruitment and the problem of high attrition in order to address the serious manpower shortage facing pathology. When shortages occur in specialties, practitioners tend to cease performing the most time-intensive tasks (eg, autopsy). However, shortages of the magnitude predicted for pathology suggest that many more tasks traditionally performed by pathologists may very well be in jeopardy. In such a setting, other specialties (especially subspecialties) are likely to fill the void. This is likely to be catalyzed by the emergence of the new resource-based relative-value scale. Subspecialties in medicine and surgery will be looking for additional ways to retain income when they cannot expect as much for their services as before. This scenario is especially worrisome given the necessity for the practice of pathology to expand into the domain of molecular biology. Unless problems causing the shortage in pathology manpower are addressed, not only are our traditional practices threatened, we are also likely to have inadequate manpower to take advantage of those areas crucial for the future of pathology.

journal_name

Hum Pathol

journal_title

Human pathology

authors

Vance RP,Prichard RW,Smith RD

doi

10.1016/0046-8177(91)90258-q

subject

Has Abstract

pub_date

1991-11-01 00:00:00

pages

1067-76

issue

11

eissn

0046-8177

issn

1532-8392

pii

0046-8177(91)90258-Q

journal_volume

22

pub_type

杂志文章
  • Positive troponin T without cardiac involvement in inclusion body myositis.

    abstract::Cardiac troponin T (cTnT) is considered as a specific marker for acute myocardial infarction. Here, we present a case with elevated cTnT, determined by a third-generation assay, without signs of a myocardial lesion. Routine investigation of a 66-year-old female patient with indolent B-cell lymphoma revealed increased ...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/j.humpath.2005.06.009

    authors: Schwarzmeier JD,Hamwi A,Preisel M,Resl C,Preusser M,Sluga E,Horcher E,Shehata MM

    更新日期:2005-08-01 00:00:00

  • Presence of tumor necrosis factor alpha and interleukin-6 in renal mesangial cells of lupus nephritis patients.

    abstract::Tumor necrosis factor alpha (TNF alpha) and interleukin-6 (IL-6) antigenic sites were shown within the resident glomerular mesangial cells of lupus nephritis patients applying the colloidal gold immunocytochemical approach at the electron microscopic level. Using specific polyclonal antibodies against human recombinan...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/0046-8177(95)90253-8

    authors: Malide D,Russo P,Bendayan M

    更新日期:1995-05-01 00:00:00

  • Cyclin E immunoexpression in breast ductal carcinoma: pathologic correlations and prognostic implications.

    abstract::Abnormalities of the cell cycle are present in all neoplasms. Cyclin E, which regulates the G1/S phase transition of the cell cycle, plays an important role in many different cancers. To further investigate the role of cyclin E in invasive breast ductal carcinomas in South African women, representative sections from 1...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1053/hupa.2001.21141

    authors: Donnellan R,Kleinschmidt I,Chetty R

    更新日期:2001-01-01 00:00:00

  • Nesidiodysplasia--a histologic entity?

    abstract::Five cases of persistent neonatal hyperinsulinemic hypoglycemia (PNHH) were studied by a combined immunofluorescent and Feulgen technique under a computerized microscope which was used to measure the area and absorbance of beta cell nuclei. An increase of 16% was found in the nuclear area and absorbance of the beta ce...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/s0046-8177(88)80154-0

    authors: Ariel I,Kerem E,Schwartz-Arad D,Bartfeld E,Ron N,Pizov G,Zajicek G

    更新日期:1988-10-01 00:00:00

  • Mixed endometrial carcinomas with a "low-grade serous"-like component: a clinicopathologic, immunohistochemical, and molecular genetic study.

    abstract::Recently, we reported 2 mixed endometrioid endometrial carcinomas with a "low-grade serous"-like component, which does not fit into any of the 4 molecular groups described by The Cancer Genome Atlas. To understand the nature of these tumors, we have done an immunohistochemical and molecular genetic study of these 2 ca...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/j.humpath.2017.10.016

    authors: Espinosa I,D'Angelo E,Corominas M,Gonzalez A,Prat J

    更新日期:2018-01-01 00:00:00

  • Human epidermal growth factor receptor 2, Na+/H+ exchanger regulatory factor 1, and breast cancer susceptibility gene-1 as new biomarkers for familial breast cancers.

    abstract::The aim of this study is to evaluate the analysis of markers related with progression, to further characterize familial breast cancers. Here, we investigated the expression of breast cancer susceptibility gene-1, hypoxia-inducible factor-1α, vascular endothelial growth factor receptor 1, and Na+/H+ exchanger regulator...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/j.humpath.2011.01.010

    authors: Mangia A,Malfettone A,Saponaro C,Tommasi S,Simone G,Paradiso A

    更新日期:2011-11-01 00:00:00

  • The majority of metachronous CIN1 and CIN3 lesions are caused by different human papillomavirus genotypes, indicating that the presence of CIN1 seems not to determine the risk for subsequent detection of CIN3.

    abstract::Cervical intraepithelial neoplasia (CIN) is historically viewed as a progressive biologic continuum leading to cervical cancer. However, it has been questioned whether CIN1 lesions ever progress. To this end, we evaluated the number of patients with a CIN3 and a previous CIN1 diagnosis. Subsequently, metachronous CIN1...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/j.humpath.2013.10.014

    authors: Litjens RJ,Van de Vijver KK,Hopman AH,Ummelen MI,Speel EJ,Sastrowijoto SH,Van Gorp T,Slangen BF,Kruitwagen RF,Krüse AJ

    更新日期:2014-02-01 00:00:00

  • Abnormal formation of the prothrombinase complex: factor V deficiency and related disorders.

    abstract::A membrane-bound, Ca2-dependent complex of the cofactor factor Va and the enzyme factor Xa comprises the prothrombinase coagulation complex, which catalyzes the proteolytic conversion of prothrombin to thrombin. In normal hemostasis, the platelet is presumed to supply the surface membrane and thus constitutes the site...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/s0046-8177(87)80334-9

    authors: Tracy PB,Mann KG

    更新日期:1987-02-01 00:00:00

  • Promyelocytic leukemia zinc finger and histone H1.5 differentially stain low- and high-grade pulmonary neuroendocrine tumors: a pilot immunohistochemical study.

    abstract::Promyelocytic leukemia zinc finger is a zinc finger transcription factor that functions as a transcriptional repressor. Its expression has been shown to be down-regulated in hematopoietic, melanocytic, and mesothelial malignancies. Histone H1.5 is a variant of histone H1, a family of linker proteins that organizes chr...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/j.humpath.2012.11.014

    authors: Hechtman JF,Beasley MB,Kinoshita Y,Ko HM,Hao K,Burstein DE

    更新日期:2013-07-01 00:00:00

  • Diffuse and localized tenosynovial giant cell tumor and pigmented villonodular synovitis: a clinicopathologic and flow cytometric DNA analysis.

    abstract::The DNA content and proliferative indexes of seven cases of tenosynovial giant cell tumor of tendon sheath, diffuse type (TGCT-D); 11 cases of tenosynovial giant cell tumor of tendon sheath, localized type (TGCT-L); and seven cases of pigmented villonodular synovitis (PVNS) were analyzed by flow cytometry in an attemp...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/0046-8177(92)90340-9

    authors: Abdul-Karim FW,el-Naggar AK,Joyce MJ,Makley JT,Carter JR

    更新日期:1992-07-01 00:00:00

  • The evolving landscape of HPV-related neoplasia in the head and neck.

    abstract::Human papilloma virus (HPV) has emerged as the key etiologic driver in the majority of cancers at head and neck mucosal sites. First described in the uterine cervix and subsequently in oropharyngeal squamous cell carcinomas, the morphologic and clinical spectrum of HPV-related neoplasia has continued to expand and now...

    journal_title:Human pathology

    pub_type: 杂志文章,评审

    doi:10.1016/j.humpath.2019.09.001

    authors: Devins KM,Tetzlaff MT,Baloch Z,LiVolsi VA

    更新日期:2019-12-01 00:00:00

  • Use of remote video microscopy (telepathology) as an adjunct to neurosurgical frozen section consultation.

    abstract::We investigated the use of remote video microscopy (telepathology) to assist in the diagnosis of 52 neurosurgical frozen section cases. The TelMed system (Discovery Medical Systems, Overland Park, KS), in which the referring pathologist selects appropriate fields for transmission to the consultant, was used for the st...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/0046-8177(93)90142-4

    authors: Becker RL Jr,Specht CS,Jones R,Rueda-Pedraza ME,O'Leary TJ

    更新日期:1993-08-01 00:00:00

  • What can we learn from the errors in the frozen section diagnosis of pulmonary carcinoid tumors? An evidence-based approach.

    abstract::The intraoperative diagnosis of pulmonary neuroendocrine tumors can be difficult. Frozen section diagnosis was requested on 87 neuroendocrine tumors including 58 typical carcinoids, 8 atypical carcinoids, 18 large cell neuroendocrine carcinomas, and 3 small cell carcinomas from 2405 patients that underwent frozen sect...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/j.humpath.2008.07.017

    authors: Gupta R,Dastane A,McKenna RJ Jr,Marchevsky AM

    更新日期:2009-01-01 00:00:00

  • Aberrant expression of δ-like ligand 4 contributes significantly to axillary lymph node metastasis and predicts postoperative outcome in breast cancer.

    abstract::δ-Like ligand 4 (DLL4), a ligand for the Notch family of receptors, forecasts the prognosis of several human malignancies. However, the expression and role of DLL4 in breast cancer remain largely unknown. In the present study, we first evaluated whether the overexpression of DLL4 could be used as an indicator of axill...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/j.humpath.2014.04.025

    authors: Xiao M,Yang S,Ning X,Huang Y

    更新日期:2014-11-01 00:00:00

  • Staging of colorectal cancers based on elastic lamina invasion.

    abstract::Peritoneal involvement in colorectal cancer (CRC) has prognostic significance and is an important parameter in pathologic tumor staging. Restaging of tumors based on peritoneal elastic lamina invasion (ELI) has prognostic significance in CRCs classified as pathologic stage 3 tumors without regional lymph node metastas...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/j.humpath.2018.10.019

    authors: Liang WY,Wang YC,Hsu CY,Yang SH

    更新日期:2019-03-01 00:00:00

  • Matrix metalloproteinase-2 and matrix metalloproteinase-9 codistribute with transcription factors RUNX1/AML1 and ETV5/ERM at the invasive front of endometrial and ovarian carcinoma.

    abstract::Several matrix metalloproteinases (MMPs) are implicated in the degradation of the epithelial basement membrane (BM), invasiveness, and malignancy of endometrial and ovarian carcinomas. We have recently proposed a cooperative role for RUNX1/AML1 and ETV5/ERM in myometrial infiltration during endometrioid endometrial in...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/j.humpath.2010.01.025

    authors: Planagumà J,Liljeström M,Alameda F,Bützow R,Virtanen I,Reventós J,Hukkanen M

    更新日期:2011-01-01 00:00:00

  • The significance of cystic hygroma in fetuses.

    abstract::Cystic hygroma of the neck was observed in seven spontaneously aborted, severely autolyzed female fetuses. Four of five karyotyped cases had the 45,XO karyotype; one was a normal female, 46,XX. Diagnostic features associated with monosomy X in fetuses, which were observed in six of these cases, include large cystic hy...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/s0046-8177(84)80331-7

    authors: Byrne J,Blanc WA,Warburton D,Wigger J

    更新日期:1984-01-01 00:00:00

  • Papovavirus and squamous cell carcinoma.

    abstract::There is considerable interest in the role of the human wart virus in the pathogenesis of squamous cell carcinoma. Mucosal wart virus infections may produce considerable epithelial atypia and have eventuated in carcinoma in "normal" individuals in some instances. The verruciform lesions of patients with epidermodyspla...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/s0046-8177(81)80108-6

    authors: Gisser SD

    更新日期:1981-02-01 00:00:00

  • Morphologic and immunophenotypic analysis of desmoid-type fibromatosis after radiation therapy.

    abstract::The morphologic changes seen in desmoid-type fibromatosis after radiotherapy have not been well studied, and the degree of cytologic atypia, cellularity, mitotic activity, and lesional necrosis found in desmoid-type fibromatosis treated with ionizing radiation has not been thoroughly assessed. Therefore, we evaluated ...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/j.humpath.2011.11.002

    authors: Cates JM,Black J,Wolfe CC,Shinohara ET,Holt GE,Keedy VL,Hande KR,Homlar KC,Halpern JL,Schwartz HS,Troutman A,Coffin CM

    更新日期:2012-09-01 00:00:00

  • Superficial cervicovaginal myofibroblastoma: fourteen cases of a distinctive mesenchymal tumor arising from the specialized subepithelial stroma of the lower female genital tract.

    abstract::The clinicopathologic features and immunohistochemical profiles of 14 cases of a distinctive mesenchymal tumor that arises in the superficial lamina propria of the cervix and vagina and is histologically distinguishable from mesodermal (fibroepithelial) stromal polyp, including the cellular (pseudosarcomatous) variant...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1053/hupa.2001.25588

    authors: Laskin WB,Fetsch JF,Tavassoli FA

    更新日期:2001-07-01 00:00:00

  • Typical and atypical carcinoid tumors of the lung: a clinicopathological correlation of 783 cases with emphasis on histological features.

    abstract::We present 783 surgical resections of typical and atypical carcinoid tumors of the lung identified in the pathology files of 20 different pathology departments. All cases were critically reviewed for clinical and pathological features and further correlated with clinical outcomes. Long-term follow-up was obtained in a...

    journal_title:Human pathology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.humpath.2020.02.005

    authors: Moran CA,Lindholm KE,Brunnström H,Langman G,Jang SJ,Spagnolo D,Chai SM,Laycock A,Falconieri G,Pizzolitto S,de Pellegrin A,Medeiros F,Edmunds L,Catarino A,Cunha F,Ro J,Pina-Oviedo S,Torrealba J,Coppola D,Petersson F

    更新日期:2020-04-01 00:00:00

  • Telomerase activity in ordinary meningiomas predicts poor outcome.

    abstract::Telomerase, the enzyme that stabilizes telomere length, is reactivated with almost all cancer types, and it may be necessary for unlimited cell proliferation. Assessment of malignancy in ordinary meningiomas is inconclusive because no clear-cut correlation exists between aggressive clinical behavior and histological f...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/s0046-8177(97)90029-0

    authors: Langford LA,Piatyszek MA,Xu R,Schold SC Jr,Wright WE,Shay JW

    更新日期:1997-04-01 00:00:00

  • Reactive vascular lesion of nasal septum simulating angiosarcoma in a cocaine abuser.

    abstract::We report the case of an exuberant ulcerative angiomatoid nasal lesion in a cocaine abuser. The lesion was made up of polymorphous endothelial cells with occasional mitoses, arranged in a lobular pattern with infiltrative-looking areas. There were extensive areas of thrombosis with focal recanalization. Intravascular ...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/s0046-8177(00)80226-9

    authors: Alameda F,Fontane J,Corominas JM,Lloreta J,Serrano S

    更新日期:2000-02-01 00:00:00

  • Clinicopathological analysis of intraductal proliferative lesions of prostate: intraductal carcinoma of prostate, high-grade prostatic intraepithelial neoplasia, and atypical cribriform lesion.

    abstract::Intraductal carcinoma of the prostate (IDC-P) and high-grade prostatic intraepithelial neoplasia (HGPIN) are two distinct intraductal lesions; the former is usually associated with invasive carcinoma and has an aggressive course while the latter is considered a precancerous lesion. In addition, there are morphological...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/j.humpath.2014.03.011

    authors: Miyai K,Divatia MK,Shen SS,Miles BJ,Ayala AG,Ro JY

    更新日期:2014-08-01 00:00:00

  • Evaluating breast lymphoplasmacytic infiltrates: a multiparameter immunohistochemical study, including assessment of IgG4.

    abstract::Lymphoplasmacytic infiltrates in the breast, a modified skin appendage, include lymphocytic lobulitis, other nonspecific benign proliferations, and mucosa-associated lymphoid tissue (MALT)-type lymphoma. Distinguishing these entities, all of which may be B-cell rich and may have associated sclerosis, can be difficult....

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/j.humpath.2015.04.006

    authors: Berg AN,Soma L,Clark BZ,Swerdlow SH,Roth CG

    更新日期:2015-08-01 00:00:00

  • CD30-positive anaplastic large cell lymphoma in a human T-cell lymphotropic virus-I endemic area.

    abstract::Clinicopathological and cytogenetic studies were performed on specimens from 43 patients with CD30-positive anaplastic large cell lymphoma (ALCL). All patients were born and lived in a human T-cell lymphotropic virus (HTLV)-I endemic area. Twenty-one patients (48.8%) had serum anti-HTLV-I antibody suggesting the prese...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/0046-8177(95)90165-5

    authors: Takeshita M,Ohshima K,Akamatsu M,Ohgami A,Kikuchi M,Suzumiya J,Uike N,Okamura T,Nakayama J

    更新日期:1995-06-01 00:00:00

  • Histopathologic evaluation of application of labeled neoglycoproteins in primary bronchus carcinoma.

    abstract::Neoglycoproteins are readily available conjugates of a histochemically inert carrier protein and histochemically crucial carbohydrate moieties which are covalently attached to the carrier protein by chemical synthesis. Biotinylation renders these conjugates detectable in formalin-fixed, paraffin-embedded tissue sectio...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/0046-8177(89)90045-2

    authors: Kayser K,Gabius HJ,Ciesiolka T,Ebert W,Bach S

    更新日期:1989-04-01 00:00:00

  • Thromboangiitis obliterans (Buerger's disease) in a saphenous vein arterial graft.

    abstract::Thromboangiitis obliterans (Buerger's disease) is an uncommon variety of occlusive peripheral vascular disease, occurring predominantly in young male tobacco smokers. The vascular lesion in the acute stage of thromboangiitis obliterans is distinctive and affects both the arteries and veins. Described here is an unusua...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/s0046-8177(87)80174-0

    authors: Lie JT

    更新日期:1987-04-01 00:00:00

  • Overexpression of BCAT1 is a prognostic marker in gastric cancer.

    abstract::As one form of branched-chain amino-acid transaminase (BCAT) enzymes, It has been found that up-regulation of BCAT1 is associated with poor prognosis in numerous types of tumors, but studies on the role of BCAT1 expression in gastric cancer (GC) are rare. The aims of this study were to detect BCAT1 expression in GC an...

    journal_title:Human pathology

    pub_type: 杂志文章

    doi:10.1016/j.humpath.2018.02.003

    authors: Xu Y,Yu W,Yang T,Zhang M,Liang C,Cai X,Shao Q

    更新日期:2018-05-01 00:00:00

  • Extramammary Paget's disease associated with prostate adenocarcinoma.

    abstract::A case of scrotal and penile extramammary Paget's disease (EMPD) and concurrent prostate adenocarcinoma in a 59-year-old patient is presented. Immunohistochemically, the tumor cells of both the EMPD and prostate stained positively for prostate-specific antigen. Six previously reported cases of EMPD associated with pro...

    journal_title:Human pathology

    pub_type: 杂志文章,评审

    doi:10.1016/0046-8177(94)90229-1

    authors: Sleater JP,Ford MJ,Beers BB

    更新日期:1994-06-01 00:00:00