Lymphomatoid granulomatosis: report of a case without pulmonary lesions and with ischemic colitis, probably a sequel to granulomatosis.

abstract：:Plasma cells are the hallmark of chronic endometritis but are not specific for upper tract infection. Plasma cells have also been noted in hormonally mediated endometrial disorders in association with gland architectural changes ("disordered proliferative" and "anovulatory" patterns), and stromal breakdown. We reviewe...

journal_title：Human pathology

authors： Gilmore H,Fleischhacker D,Hecht JL

更新日期：2007-04-01 00:00:00

abstract：:Arginase-1 has been demonstrated as a marker for hepatocellular carcinoma (HCC) with higher sensitivity and specificity than HepPar-1 and glypican-3. However, its sensitivity is diminished in moderately and poorly differentiated HCCs. In the current study, we evaluated the utility of AGXT1 as a diagnostic marker. Immu...

journal_title：Human pathology

authors： Zhao CL,Hui Y,Wang LJ,Yang D,Yakirevich E,Mangray S,Huang CK,Lu S

更新日期：2018-10-01 00:00:00

abstract：:A century or so ago, pediatrics and pediatric pathology did not exist. Then, many fetuses/newborns died in utero or shortly after birth. With time, the issue of sepsis was addressed, and a greater number of newborns survived. Gradually, in this soil, the disciplines of pediatrics and pediatric nursing arose, as some r...

journal_title：Human pathology

authors： Nezelof C,Seemayer TA,Bridge JA

更新日期：2010-03-01 00:00:00

abstract：:A 39-year-old female patient was admitted to explore chronic renal failure. Clinical history included silicone breast implants. Clinical examination was normal. Urinalysis revealed tubular proteinuria with Bence-Jones κ protein. Monoclonal immunoglobulin G κ and free monoclonal κ-light chains (LCs) were revealed by se...

journal_title：Human pathology

authors： Figueres ML,Beaume J,Vuiblet V,Rabant M,Bassilios N,Herody M,Touchard G,Noël LH

更新日期：2015-01-01 00:00:00

abstract：:The surgical pathologist is often called upon to make a rapid decision about the malignant potential of a soft tissue tumor. These tumors have specific stromas that support growth and endow the tumor with unique qualities, as well as being manifestations of the phenotypic expression of tumor cells. Collagen, the major...

journal_title：Human pathology

authors： Stern R

更新日期：1981-09-01 00:00:00

abstract：:Intraductal papillary mucinous neoplasm is characterized by cystically dilated main and/or branch pancreatic duct with mucus. According to the degree of atypia, intraductal papillary mucinous neoplasm is classified into 3 groups: adenoma, borderline, and carcinoma. Furthermore, intraductal papillary mucinous neoplasm ...

journal_title：Human pathology

authors： Hayashi A,Aishima S,Miyasaka Y,Nakata K,Morimatsu K,Oda Y,Nagai E,Oda Y,Tanaka M,Tsuneyoshi M

更新日期：2010-11-01 00:00:00

abstract：:Two cases of lymphadenopathy resulting from a lymph node foreign body reaction to silicone are presented. In each case lymph node biopsy was performed because of the clinical suspicion of neoplastic disease. Histologic study in both cases revealed no evidence of malignant disease, but rather demonstrated multinucleate...

journal_title：Human pathology

authors： Kircher T

更新日期：1980-05-01 00:00:00

abstract：:RBM (RNA-binding motif) protein is a marker of male germ cells. This protein is encoded by the Azoospermia factor region-b (AZF-b) of the human Y chromosome and is expressed exclusively in the male germ cell line, that is, spermatogonia, spermatocytes, and round spermatids. The authors analyzed the expression of the R...

journal_title：Human pathology

authors： Lifschitz-Mercer B,Elliott DJ,Leider-Trejo L,Schreiber-Bramante L,Hassner A,Eisenthal A,Maymon BB

更新日期：2000-09-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) promotes growth of blood or lymphatic vessels. The aim of the current study is to identify relationships between VEGF-A and VEGF-C, and their impact in angiogenesis and metastases in thyroid cancers. VEGF-A and VEGF-C mRNA and protein expression was investigated in 136 thyroid...

journal_title：Human pathology

authors： Salajegheh A,Pakneshan S,Rahman A,Dolan-Evans E,Zhang S,Kwong E,Gopalan V,Lo CY,Smith RA,Lam AK

更新日期：2013-10-01 00:00:00

abstract：:(90)Yttrium (Therasphere) microspheres administered via hepatic artery are a valuable option for treatment of hepatocellular carcinoma. This therapy targets tumor nodules while largely sparing hepatic parenchyma. This retrospective study examines liver explants from 13 adult patients with hepatocellular carcinoma who ...

journal_title：Human pathology

authors： Nalesnik MA,Federle M,Buck D,Fontes P,Carr BI

更新日期：2009-01-01 00:00:00

abstract：:In general, the large cell lymphomas are a cytogenetically heterogeneous group of diseases, and the cytogenetic findings do not correlate with morphological findings in this group of malignant lymphomas. The CD30-positive anaplastic large cell lymphomas, however, are thought to be an exception, with the t(2;5) reporte...

journal_title：Human pathology

authors： Arber DA,Sun LH,Weiss LM

更新日期：1996-06-01 00:00:00

abstract：:Gastrointestinal stromal tumor (GIST) is the preferred term for mesenchymal tumors specific for the gastrointestinal tract (60% in stomach, 30% small intestine, 10% elsewhere). GISTs include most tumors previously designated as leiomyoma, cellular leiomyoma, leiomyoblastoma, and leiomyosarcoma. However, in the esophag...

journal_title：Human pathology

authors： Miettinen M,Sarlomo-Rikala M,Lasota J

更新日期：1999-10-01 00:00:00

abstract：:Hypertrophic cardiomyopathy phenotype is shared by heterogeneous entities. The purpose of the study was to evaluate the diagnostic role of left ventricular endomyocardial biopsy. One hundred fifty-one consecutive patients with unexplained left ventricular hypertrophy and normal/elevated QRS voltages or left bundle-bra...

journal_title：Human pathology

authors： Frustaci A,Russo MA,Chimenti C

更新日期：2013-01-01 00:00:00

abstract：:Transitional cell (urothelial) carcinoma of the bladder is the second most common urologic malignancy and is one of the best understood neoplasms, with relatively well-defined pathogenetic pathways, natural history, and tumor biology. Conventional clinical and pathologic parameters are widely used to grade and stage t...

journal_title：Human pathology

authors： Cheng L,Zhang S,MacLennan GT,Williamson SR,Lopez-Beltran A,Montironi R

更新日期：2011-04-01 00:00:00

abstract：:Papillary renal cell carcinoma (PRCC) is currently divided in 2 subtypes. We reviewed a large cohort of PRCC and correlated subtype, morphological features and diagnostic marker expression with overall survival (OS) to uncover differences between the 2 subtypes. Three hundred seventy-six renal tumors initially diagnos...

journal_title：Human pathology

authors： Polifka I,Agaimy A,Herrmann E,Spath V,Trojan L,Stöckle M,Becker F,Ströbel P,Wülfing C,Schrader AJ,Barth P,Staehler M,Stief C,Hohenfellner M,Macher-Göppinger S,Wullich B,Noldus J,Brenner W,Roos FC,Walter B,Otto W,

更新日期：2019-01-01 00:00:00

abstract：:The aim of the current study was to test whether the grade group assessed in the index tumor nodule predicts biochemical recurrence after surgery. The study cohort series included 144 consecutive patients treated by laparoscopic radical prostatectomy. The following parameters were evaluated in each case: type of radic...

journal_title：Human pathology

authors： Vau N,Henriques V,Cheng L,Blanca A,Fonseca J,Montironi R,Cimadamore A,Lopez-Beltran A

更新日期：2019-11-01 00:00:00

abstract：:Human papilloma virus (HPV) has emerged as the key etiologic driver in the majority of cancers at head and neck mucosal sites. First described in the uterine cervix and subsequently in oropharyngeal squamous cell carcinomas, the morphologic and clinical spectrum of HPV-related neoplasia has continued to expand and now...

journal_title：Human pathology

authors： Devins KM,Tetzlaff MT,Baloch Z,LiVolsi VA

更新日期：2019-12-01 00:00:00

abstract：:Endometrioid endometrial carcinomas (EECs) are correlated with high serum levels of androgens and estrogen. We hypothesized that Leydig cells and ovarian stromal hyperplasia contribute to postmenopausal ovarian androgen production and are observed more frequently in EEC patients. Ovaries of postmenopausal women with E...

journal_title：Human pathology

authors： Reijnen C,Küsters-Vandevelde HVN,Abbink K,Zusterzeel PLM,van Herwaarden AE,van der Laak JAWM,Massuger LFAG,Snijders MPLM,Pijnenborg JMA,Bulten J

更新日期：2019-03-01 00:00:00

abstract：:The introduction of next-generation sequencing has broadened the genetic landscape of myeloproliferative neoplasms (MPNs) beyond JAK2, MPL, and CALR. However, the biological role and clinical impact of most other mutations are not well defined. We interrogated 101 genes in 143 BCR-ABL1-negative MPNs in chronic phase f...

journal_title：Human pathology

authors： Boiocchi L,Hasserjian RP,Pozdnyakova O,Wong WJ,Lennerz JK,Le LP,Dias-Santagata D,Iafrate AJ,Hobbs GS,Nardi V

更新日期：2019-04-01 00:00:00

abstract：:A young male with Buerger's disease who had previously required a left leg amputation died in renal failure and sepsis. Postmortem examination revealed an obliterative lesion of the celiac artery, which resulted in hepatic, splenic, and pancreatic infarctions. Celiac artery involvement represents an unusual manifestat...

journal_title：Human pathology

authors： Sobel RA,Ruebner BH

更新日期：1979-01-01 00:00:00

abstract：:Pityriasis lichenoides (PL) is a papulosquamous disorder often considered a form of reactive dermatosis and classified with small plaque parapsoriasis (digitate dermatosis). However, some patients with PL have developed large plaque parapsoriasis (LPP) and mycosis fungoides (MF), and lymphoid atypia and T-cell clonali...

journal_title：Human pathology

authors： Magro C,Crowson AN,Kovatich A,Burns F

更新日期：2002-08-01 00:00:00

abstract：:Many have wondered what might have become of the totalitarian state Lenin founded on merciless terror, had he not died so young. He was 52 and at the height of his power when he had his first stroke. Six months later he had another and then a third stroke three months after that. He died 3 months shy of his 54th birth...

journal_title：Human pathology

authors： Vinters H,Lurie L,Mackowiak PA

更新日期：2013-10-01 00:00:00

abstract：:Invasive squamous cell carcinoma (SCC) of the cervix involves the progression of premalignant cervical intraepithelial neoplasia (CIN) and is associated with persistent human papillomavirus infection. Most CINs will regress, and the challenge is to identify the lesions likely to progress to invasive cancer. We evaluat...

journal_title：Human pathology

authors： Velez-Perez A,Wang XI,Li M,Zhang S

更新日期：2017-01-01 00:00:00

abstract：:Chemokine receptor, CXCR3, has been increasingly reported to be involved in tumorigenesis and tumor progression, but limited data are available regarding the expression of CXCR3 in gastric cancer (GC). In the present study, the expressions of CXCR3 and its variants were detected in 96 GC and corresponding nontumor gas...

journal_title：Human pathology

authors： Hu M,Li K,Maskey N,Xu Z,Yu F,Peng C,Li Y,Yang G

更新日期：2015-12-01 00:00:00

abstract：:Molecular diagnostics increasingly direct the management of thyroid nodules with an indeterminate cytologic diagnosis. This study was undertaken to correlate cytomorphologic features with the molecular profiles in an effort to identify features predictive of molecular aberrations. One hundred eighty-nine thyroid nodul...

journal_title：Human pathology

authors： Shahi M,Bloechl SJ,Vogel RI,Shrestha R,Krigman HR,Evasovich M,Burmeister LA,Amin K

更新日期：2019-11-01 00:00:00

abstract：:Although rare, synovial sarcoma (SS) is one of the most common soft tissue sarcomas affecting young adults. To investigate potential tumor markers related to synovial sarcoma prognosis, we carried out a single-institution retrospective analysis of 103 patients diagnosed with SS between 1980 and 2009. Clinical outcome ...

journal_title：Human pathology

authors： Charbonneau B,Vogel RI,Manivel JC,Rizzardi A,Schmechel SC,Ognjanovic S,Subramanian S,Largaespada D,Weigel B

更新日期：2013-09-01 00:00:00

abstract：:A better knowledge of the biological aggressiveness of individual tumors could facilitate the selection of treatment in prostate cancer patients. This study assesses the influence of histological and molecular features in core needle biopsy specimens of prostate cancer on tumor-specific survival. Formalin-fixed core n...

journal_title：Human pathology

authors： Bubendorf L,Tapia C,Gasser TC,Casella R,Grunder B,Moch H,Mihatsch MJ,Sauter G

更新日期：1998-09-01 00:00:00

abstract：:AT-rich interactive domain 1A (ARID1A) is tumor suppressor gene that interacts with BRG1 adenosine triphosphatase to form a SWI/SNF chromatin remodeling protein complex. Inactivation of ARID1A has been described in several neoplasms, including epithelial ovarian and endometrial carcinomas, and has been correlated with...

journal_title：Human pathology

authors： Faraj SF,Chaux A,Gonzalez-Roibon N,Munari E,Ellis C,Driscoll T,Schoenberg MP,Bivalacqua TJ,Shih IeM,Netto GJ

更新日期：2014-11-01 00:00:00

abstract：:We studied c-erbB-2, p53, and nm23 gene products in 112 primary breast carcinomas. Fifty patients were aged 35 years or younger, and 62 were aged 36 to 50. Clinicopathological criteria including clinical stage, hormone receptor status, histological types, histological grades, and lymph node status, were reviewed. Dise...

journal_title：Human pathology

authors： Bertheau P,Steinberg SM,Merino MJ

更新日期：1998-04-01 00:00:00

abstract：:Sex-determining region Y-box 2 is proposed to be a key transcription factor in embryonic stem cells. The known roles of sex-determining region Y-box 2 in development and cell differentiation suggest that it is relevant to the aberrant growth of tumor cells. Thus, sex-determining region Y-box 2 may play an important ro...

journal_title：Human pathology

authors： Zhang J,Chang DY,Mercado-Uribe I,Liu J

更新日期：2012-09-01 00:00:00