Alanine-glyoxylate aminotransferase 1 (AGXT1) is a novel marker for hepatocellular carcinomas.

abstract：:This study tested whether concordance could be achieved for abnormal inflammation in the basal decidua of placental specimens among 6 pathologists experienced in placental pathology. Thirty microscope slides were evaluated by the pathologists for chronic deciduitis. They also scored the severity and extent of inflamma...

journal_title：Human pathology

authors： Khong TY,Bendon RW,Qureshi F,Redline RW,Gould S,Stallmach T,Lipsett J,Staples A

更新日期：2000-03-01 00:00:00

abstract：:The outcomes of patients with stage I non-small-cell lung cancer (NSCLC) vary greatly, with a 5-year survival rate of approximately 60%. This study evaluated a number of molecular markers that may aid in predicting prognosis in stage I NSCLC after surgical resection. Immunohistochemical (IHC) staining of p53, HER-2/ne...

journal_title：Human pathology

authors： Han H,Landreneau RJ,Santucci TS,Tung MY,Macherey RS,Shackney SE,Sturgis CD,Raab SS,Silverman JF

更新日期：2002-01-01 00:00:00

abstract：:Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF), is an angiogenic factor that plays important roles in tumor growth. Angiogenesis studies on VEGF deal with various types of malignant tumors, but very little is known about the role or significance of VEGF in human thyroid neo...

journal_title：Human pathology

authors： Katoh R,Miyagi E,Kawaoi A,Hemmi A,Komiyama A,Oyama T,Shibuya M

更新日期：1999-08-01 00:00:00

abstract：:The surgical pathologist is often called upon to make a rapid decision about the malignant potential of a soft tissue tumor. These tumors have specific stromas that support growth and endow the tumor with unique qualities, as well as being manifestations of the phenotypic expression of tumor cells. Collagen, the major...

journal_title：Human pathology

authors： Stern R

更新日期：1981-09-01 00:00:00

abstract：:Endothelial cell injury may contribute to the progression of various glomerular diseases. In the present study, we examined glomerular capillary injury in acute and chronic glomerular lesions in patients with Immunoglobulin A nephropathy (IgAN). We selected renal biopsy samples of IgAN (n = 200), and glomerular capill...

journal_title：Human pathology

authors： Kusano T,Takano H,Kang D,Nagahama K,Aoki M,Morita M,Kaneko T,Tsuruoka S,Shimizu A

更新日期：2016-03-01 00:00:00

abstract：:To establish whether an intramural left anterior descending coronary artery (LADA) is a simple anatomic or a singularly pathologic variant we studied 39 hearts, each with an intramural course of the LADA and no coronary artery disease, valvular derangement, cardiomyopathy, or congenital anomaly. Seventeen of the 39 he...

journal_title：Human pathology

authors： Morales AR,Romanelli R,Tate LG,Boucek RJ,de Marchena E

更新日期：1993-07-01 00:00:00

abstract：:Three cases of giant cell carcinoma of lung and six other lung carcinomas with large atypical cell formation were studied by both light and electron microscopy. The giant cell carcinomas showed unique light and electron microscopic features, whereas large atypical cells from other lung carcinomas usually retained some...

journal_title：Human pathology

authors： Wang NS,Seemayer TA,Ahmed MN,Knaack J

更新日期：1976-01-01 00:00:00

abstract：:To assess the proliferative activity of renal cell carcinoma (RCC-A) in patients with acquired cystic disease of the kidney (ACDK) after long-term hemodialysis, we analyzed cell cycle, DNA ploidy, and S-phase fraction by flow cytometry (FCM) and proliferating cell nuclear antigen (PCNA) labeling index by immunohistoch...

journal_title：Human pathology

authors： Ikeda R,Tanaka T,Moriyama MT,Kawamura K,Miyazawa K,Suzuki K

更新日期：2002-02-01 00:00:00

abstract：:Cellular crescents are typically inflammatory and associated with rapidly progressive glomerulonephritis. Their pathogenesis involves glomerular basement membrane rupture due to circulating or intrinsic factors. Crescents associated with diabetic glomerulosclerosis are rarely reported. Furthermore, the nature of cells...

journal_title：Human pathology

authors： Gaut JP,Hoshi M,Jain S,Liapis H

更新日期：2014-03-01 00:00:00

abstract：:We studied c-erbB-2, p53, and nm23 gene products in 112 primary breast carcinomas. Fifty patients were aged 35 years or younger, and 62 were aged 36 to 50. Clinicopathological criteria including clinical stage, hormone receptor status, histological types, histological grades, and lymph node status, were reviewed. Dise...

journal_title：Human pathology

authors： Bertheau P,Steinberg SM,Merino MJ

更新日期：1998-04-01 00:00:00

abstract：:Giant cell pneumonia associated with parainfluenza virus type 3 infection and chronic poliovirus type 2 meningoencephalomyelitis are documented in an infant with combined immunologic deficiency (Swiss type). Caution should be exercised in attributing cases of giant cell pneumonia to measles virus without serologic or ...

journal_title：Human pathology

authors： Little BW,Tihen WS,Dickerman JD,Craighead JE

更新日期：1981-05-01 00:00:00

abstract：:The Sydney classification for gastritis provides guidelines for histological grading of gastric biopsies. In an ongoing study of gastric preneoplastic lesions in Chiapas, Mexico, 7 biopsies from 150 patients (4 from the antrum and 3 from the body) were obtained during endoscopy and studied histologically. The first 74...

journal_title：Human pathology

authors： Guarner J,Herrera-Goepfert R,Mohar A,Sanchez L,Halperin D,Ley C,Parsonnet J

更新日期：1999-12-01 00:00:00

abstract：:Cytochrome P-450 specific for steroid 17 alpha-hydroxylation (P-45017 alpha) was immunolocalized in normal and hyperfunctioning adrenal glands of pigs, bovines, and humans, using a specific IgG fraction raised against the enzyme. P-45017 alpha was present in the zona fasciculata (ZF) and zona reticularis (ZR), but not...

journal_title：Human pathology

authors： Sasano H,Mason JI,Sasano N

更新日期：1989-02-01 00:00:00

abstract：:The natural history of pediatric nonalcoholic steatohepatitis is still unknown; however, there are differences between adult and pediatric presentation. Apoptosis may play an important role in pathophysiologic pathways involved in liver damage and progression. Our aim was to detect early apoptosis markers, activated c...

journal_title：Human pathology

authors： Valva P,De Matteo E,Galoppo M,Pedreira A,Giacove G,Lezama C,Marco I,Galoppo MC,Preciado MV

更新日期：2008-12-01 00:00:00

abstract：:Natural killer (NK)/T-cell lymphomas represent a rare type of lymphoma derived from either activated NK cells or, rarely, cytotoxic T cells. These lesions are most commonly extranodal and tend to present as destructive lesions within the midline facial structures. Other than the nasal cavity and paranasal sinuses, sev...

journal_title：Human pathology

authors： Kaluza V,Rao DS,Said JW,de Vos S

更新日期：2006-06-01 00:00:00

abstract：:After endoscopic resection of early gastric cancer (EGC), it is imperative to accurately determine whether follow-up surgery is indicated, since this technique is used as a first line of treatment. Herein, we developed a scoring system to indicate the risk of lymph node metastasis in submucosal EGC (smEGC), and presen...

journal_title：Human pathology

authors： Kim JY,Kim WG,Jeon TY,Kim GH,Jeong EH,Kim DH,Park DY,Lauwers GY

更新日期：2013-12-01 00:00:00

abstract：:Prostate-specific membrane antigen (PSMA), a type II transmembrane metallo-peptidase highly overexpressed in prostate cancer cells, has been studied as a targeting molecule in prostate cancer. Recently, PSMA has also been found to be expressed in the neovasculature of multiple nonprostatic solid tumors. Because of its...

journal_title：Human pathology

authors： Haffner MC,Kronberger IE,Ross JS,Sheehan CE,Zitt M,Mühlmann G,Ofner D,Zelger B,Ensinger C,Yang XJ,Geley S,Margreiter R,Bander NH

更新日期：2009-12-01 00:00:00

abstract：:Patients undergoing treatment of acute lymphoblastic leukemia are at risk for fungal infections including disseminated candidiasis. We describe a case of systemic Candida albicans infection associated with life-threatening gastrointestinal hemorrhage due to unusual necrotizing vasculitis involving the gastrointestinal...

journal_title：Human pathology

authors： Sargent J,O'Marcaigh A,Smith O,Butler K,Gavin P,O'Sullivan M

更新日期：2010-04-01 00:00:00

abstract：:Pulmonary nodular lymphoid hyperplasia (PNLH) may show heavy lymphoplasmacytic infiltrates with increased immunoglobulin G4 (IgG4)-positive plasma cells as in IgG4-related disease (IgG4-RD). However, it is unclear whether PNLH could be a manifestation of IgG4-RD. A recent study reported the presence of Epstein-Barr vi...

journal_title：Human pathology

authors： Bois MC,Sekiguchi H,Ryu JH,Yi ES

更新日期：2017-01-01 00:00:00

abstract：:Bcl-2 and bcl-xL are proteins known to inhibit cell death (apoptosis). Expression of these proteins in gangliogliomas has not been extensively examined. This study retrospectively evaluates bcl-2 and bcl-x immunostaining in paraffin-embedded materials in gangliogliomas. Twenty-nine gangliogliomas in 17 males and 12 fe...

journal_title：Human pathology

authors： Prayson RA

更新日期：1999-06-01 00:00:00

abstract：:A case of xanthomatosis of the small bowel is described. Beginning with the proximal jejunum, an 85-cm segment of small bowel was distorted by regularly spaced nodular accumulations of lipid-laden macrophages that expanded the submucosa and muscularis and extended to the serosal surface. The conditions often associate...

journal_title：Human pathology

authors： Coletta U,Sturgill BC

更新日期：1985-04-01 00:00:00

abstract：:To investigate the roles of matrix metalloproteinases (MMPs) in thymic epithelial tumors, we examined the expression of MMP-2, -7, and -9; membrane-type 1 (MT1)-MMP; and tissue inhibitor of metalloproteinase-2 (TIMP-2) in 57 tumors by immunohistochemistry and in selected 15 cases by in situ hybridization. The tumors c...

journal_title：Human pathology

authors： Takahashi E,Tateyama H,Akatsu H,Fukai I,Yamakawa Y,Fujii Y,Eimoto T

更新日期：2003-12-01 00:00:00

abstract：:A case of apocrine carcinoma of the breast with psammoma bodies is described in a 69 year old man. The report emphasizes the rarity of this lesion and supports currently held beliefs about the formation of psammoma bodies. ...

journal_title：Human pathology

authors： Bryant J

更新日期：1981-08-01 00:00:00

abstract：:Sixteen cases of intermediate lymphocytic lymphoma (ILL), including eight cases with mantle zone architecture, were studied using cryostat sections, a biotin-avidin immunoperoxidase technique, and a large panel of monoclonal antibodies. The neoplastic cells invariably expressed IgM, most B lineage antigens (B1, TO15, ...

journal_title：Human pathology

authors： Strickler JG,Medeiros LJ,Copenhaver CM,Weiss LM,Warnke RA

更新日期：1988-05-01 00:00:00

abstract：:The types of collagen present in a case of elastofibroma dorsi were determined using type specific, characterized collagen antibodies. The presence of type II collagen (normally present only in articular cartilage and in selected ocular structures) is discussed with regard to the pathogenesis of this lesion, and the u...

journal_title：Human pathology

authors： Madri JA,Dise CA,LiVolsi VA,Merino MJ,Bibro MC

更新日期：1981-02-01 00:00:00

abstract：:A 51-year-old man presented with a paratracheal tumor. He had undergone resection of a thyroid tumor 15 years previously; at that time, the histologic diagnosis had been anaplastic carcinoma. When the tumor recurred, the presumptive clinical diagnosis was medullary thyroid carcinoma. Histologic examination revealed a ...

journal_title：Human pathology

authors： Asa SL,Dardick I,Van Nostrand AW,Bailey DJ,Gullane PJ

更新日期：1988-12-01 00:00:00

abstract：:A large mass in the right orbit, causing proptosis, ptosis of the right upper eyelid, and limitation to eye movements, was surgically removed from a 51-year-old woman suffering from Paget's bone disease (PBD). Histologically, a giant cell tumor of the bone (osteoclastoma) was diagnosed. No bony involvement was apparen...

journal_title：Human pathology

authors： Pecorella I,Ciardi A,Amadeo G,Baiocchini A,Marasco A,Di Tondo U

更新日期：2000-12-01 00:00:00

abstract：:Inflammatory bowel disease-associated colorectal carcinomas (IBD-CRCs) develop in a background of chronic inflammation, and thus, the molecular landscape of these tumors likely differs from that of sporadic colorectal cancer. To add to emerging data on molecular alterations present in these tumors, we analyzed our ins...

journal_title：Human pathology

authors： Alpert L,Yassan L,Poon R,Kadri S,Niu N,Patil SA,Mujacic I,Montes D,Galbo F,Wurst MN,Zhen CJ,Cohen RD,Rubin DT,Pekow JR,Weber CR,Xiao SY,Hart J,Segal J,Setia N

更新日期：2019-07-01 00:00:00

abstract：:Rosette-forming glioneuronal tumors of the fourth ventricle are rare brain tumors, and only 19 such lesions have been previously reported. This report presents the first case of a rosette-forming glioneuronal tumors arising from the spinal cord. A 44-year-old woman presented with a 15-year history of dissociated senso...

journal_title：Human pathology

authors： Anan M,Inoue R,Ishii K,Abe T,Fujiki M,Kobayashi H,Goya T,Nakazato Y

更新日期：2009-06-01 00:00:00

abstract：:The non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) and encapsulated follicular variant of papillary thyroid carcinoma (EFVPTC) are distinguished from classical papillary thyroid carcinoma with predominantly follicular architecture (CPTCPFA) by distinct histomorphologic and molecu...

journal_title：Human pathology

authors： Johnson DN,Sadow PM

更新日期：2018-12-01 00:00:00