Proliferative activity of renal cell carcinoma associated with acquired cystic disease of the kidney: comparison with typical renal cell carcinoma.

abstract：:We describe a case of simultaneous nodular sclerosing Hodgkin's disease and a granulocytic sarcoma in a cervical lymph node without any previous therapy. The condition evolved into acute myelogenous leukemia approximately 8 months after the initial diagnosis of the granulocytic sarcoma. The unexpected presence of a gr...

journal_title：Human pathology

authors： Suh YK,Shin SS,Koo CH

更新日期：1996-10-01 00:00:00

abstract：:Epithelial-mesenchymal transition (EMT) plays a pivotal role in tumor invasion and metastasis in various malignancies. ZEB2/SIP1 is an important EMT regulator and down-regulates E-cadherin expression. The present study was planned to explore status of EMT-associated markers ZEB2/SIP1 and E-cadherin in eyelid sebaceous...

journal_title：Human pathology

authors： Bhardwaj M,Sen S,Sharma A,Kashyap S,Chosdol K,Pushker N,Bajaj MS,Bakhshi S

更新日期：2015-10-01 00:00:00

abstract：:Clinicopathological and cytogenetic studies were performed on specimens from 43 patients with CD30-positive anaplastic large cell lymphoma (ALCL). All patients were born and lived in a human T-cell lymphotropic virus (HTLV)-I endemic area. Twenty-one patients (48.8%) had serum anti-HTLV-I antibody suggesting the prese...

journal_title：Human pathology

authors： Takeshita M,Ohshima K,Akamatsu M,Ohgami A,Kikuchi M,Suzumiya J,Uike N,Okamura T,Nakayama J

更新日期：1995-06-01 00:00:00

abstract：:Granulocyte alloantibodies and autoantibodies have a key role in the pathophysiology of several clinical problems. These include febrile transfusion reactions, severe pulmonary reactions to transfusion, isoimmune neonatal neutropenia, failure of effective granulocyte transfusion, autoimmune neutropenia, drug-induced n...

journal_title：Human pathology

authors： McCullough J

更新日期：1983-03-01 00:00:00

abstract：:Ultrastructural features of bilateral testicular biopsy materials, obtained from both tumor and nontumor areas of the testis of a 27-year-old man with congenital adrenal hyperplasia, revealed a number of pathologic changes. Germ cell hypoplasia and extratubular cellular hyperplasia were noticed in the nontumor portion...

journal_title：Human pathology

authors： Chakraborty J,Franco-Saenz R,Kropp K

更新日期：1983-02-01 00:00:00

abstract：:Most human papillomavirus-associated squamous intraepithelial lesions of the uterine cervix are flat; some have papillary architecture that shows a spectrum of differentiation from low-grade squamous intraepithelial lesions to high-grade squamous intraepithelial lesions. For this subset of lesions, there are few data ...

journal_title：Human pathology

authors： Liang CW,Lin MC,Hsiao CH,Lin YT,Kuo KT

更新日期：2010-03-01 00:00:00

abstract：:Spindle cell carcinoma (SpCC) is uncommon, with a predilection for the upper aerodigestive tract. Its histogenesis has not been resolved, although most authors support the sarcomatoid carcinoma concept. Ploidy analysis and proliferation indices have not been reported for laryngeal SpCCs. The authors examined the patho...

journal_title：Human pathology

authors： Lewis JE,Olsen KD,Sebo TJ

更新日期：1997-06-01 00:00:00

abstract：:Glucose transporter (GLUT)-1 is expressed in malignant tumors and correlated with poor outcome in several cancers. Biliary intraepithelial neoplasia (BilIN) is considered to be a precursor or a noninvasive lesion of invasive cholangiocarcinoma. We examined GLUT-1 and GLUT-2 expression in 149 intrahepatic cholangiocarc...

journal_title：Human pathology

authors： Kubo Y,Aishima S,Tanaka Y,Shindo K,Mizuuchi Y,Abe K,Shirabe K,Maehara Y,Honda H,Oda Y

更新日期：2014-08-01 00:00:00

abstract：:Preserving small pieces of frozen tissue for possible future ancillary studies ("tumor banking") usually involves either placing a small piece of tissue in a cryovial and snap freezing it in liquid nitrogen or embedding and freezing the tissue in a block of cryopreservation medium, such as optimal cutting temperature ...

journal_title：Human pathology

authors： Loken SD,Demetrick DJ

更新日期：2005-09-01 00:00:00

abstract：:High cathepsin D (cath-D) concentration in breast cancer cytosol is associated with increased risk of metastasis. To specify the relative contribution of the different cells types responsible for cath-D level in cytosol, we validated semiquantitative cath-D immunoperoxidase staining on formalin-fixed, paraffin-embedde...

journal_title：Human pathology

authors： Roger P,Montcourrier P,Maudelonde T,Brouillet JP,Pages A,Laffargue F,Rochefort H

更新日期：1994-09-01 00:00:00

abstract：:Geotrichum candidum was identified as an invasive organism in the terminal ileum of a man with "hairy cell" leukemia. The organism was identified on the basis of histologic and cultural characteristics. The diagnostic features of G. candidum infection are compared to those of Aspergillus and Candida species. ...

journal_title：Human pathology

authors： Jagirdar J,Geller SA,Bottone EJ

更新日期：1981-07-01 00:00:00

abstract：:Three cases of veno-occlusive disease of the liver were diagnosed in four autopsied patients who had received high-dose mitomycin C therapy followed by autologous bone marrow transplantation, and the pathologic finding are reported. Review of 27 liver, examined post mortem, of patients receiving other high-dose chemot...

journal_title：Human pathology

authors： Gottfried MR,Sudilovsky O

更新日期：1982-07-01 00:00:00

abstract：:p16INK4a immunohistochemistry (IHC) is widely used to facilitate the diagnosis of human papillomavirus (HPV)-associated cervical precancerous lesions. Although most p16 results are distinctly positive or negative, certain ones are ambiguous: they meet some but not all requirements for the "block-positive" pattern. It ...

journal_title：Human pathology

authors： Liu Y,Alqatari M,Sultan K,Ye F,Gao D,Sigel K,Zhang D,Kalir T

更新日期：2017-08-01 00:00:00

abstract：:Epidermal growth factor receptor (EGF-r) expression and tumor cell proliferation rate have been proposed as potential prognostic parameters in renal cell carcinoma (RCC). In this study, immunohistochemical stains using antibodies to EGF-r and the cell proliferation marker Ki-67 (MIB-1) were used to study the relations...

journal_title：Human pathology

authors： Moch H,Sauter G,Buchholz N,Gasser TC,Bubendorf L,Waldman FM,Mihatsch MJ

更新日期：1997-11-01 00:00:00

abstract：:In situ carcinomas must penetrate their own basement membrane to be classified as invasive, and subsequently infiltrate surrounding connective tissue and cross vascular basement membranes to metastasize hematogenously. Accordingly, in many studies, integral basement membrane components, including type IV collagen, lam...

journal_title：Human pathology

authors： Amenta PS,Briggs K,Xu K,Gamboa E,Jukkola AF,Li D,Myers JC

更新日期：2000-03-01 00:00:00

abstract：:Among women in Taiwan, thyroid cancer is the fifth most common malignant neoplasia. However, genomic profiling of papillary thyroid cancer (PTC) cases from Taiwan has not been attempted previously. We used whole-exome sequencing to identify mutations in a cohort of 19 PTC patients. Sequencing was performed using the I...

journal_title：Human pathology

authors： Chang CC,Chang YS,Huang HY,Yeh KT,Liu TC,Chang JG

更新日期：2018-08-01 00:00:00

abstract：:To determine useful factors when selecting an appropriate procedure for noninvasive ampullary neoplasia, we investigated the relationship between the location and the histomorphological/immunohistochemical characteristics of 56 noninvasive ampullary neoplasms obtained by endoscopic papillectomy (EP). All subjects were...

journal_title：Human pathology

authors： Yamamoto Y,Nemoto T,Okubo Y,Nihonyanagi Y,Ishiwatari T,Takuma K,Tochigi N,Okano N,Wakayama M,Igarashi Y,Shibuya K

更新日期：2014-09-01 00:00:00

abstract：:Basal cell carcinoma (also referred to as adenoid cystic carcinoma) is a rare tumor of the prostate. Although largely characterized as indolent, poor outcomes have been reported in a considerable fraction of cases. As yet, optimum treatment strategies for this cancer have not been developed. This study investigates pr...

journal_title：Human pathology

authors： Simper NB,Jones CL,MacLennan GT,Montironi R,Williamson SR,Osunkoya AO,Wang M,Zhang S,Grignon DJ,Eble JN,Tran T,Wang L,Baldrige LA,Cheng L

更新日期：2015-06-01 00:00:00

abstract：:Laminin and collagen have been studied in several tumor types and their immunomorphological expression correlated with tumor morphogenesis, local invasiveness, and metastatic behavior. In a series of 53 cases of pleomorphic adenomas (PA) and 16 cases of carcinomas ex-pleomorphic adenoma (Ca ex-PA), we investigated by ...

journal_title：Human pathology

authors： Félix A,Rosa JC,Fonseca I,Cidadão A,Soares J

更新日期：1999-08-01 00:00:00

abstract：:A study of so-called gelatinous transformation of the bone marrow in 14 patients is presented. The condition is characterized by the presence of extracellular "gelatinous" material, fat atrophy, and associated focal marrow hypoplasia and is often mistaken as representing edema, necrosis, or amyloid. Histochemical stud...

journal_title：Human pathology

authors： Seaman JP,Kjeldsberg CR,Linker A

更新日期：1978-11-01 00:00:00

abstract：:Pathologists are frequently asked to evaluate gastric mucosal biopsy specimens for the presence of Helicobacter pylori infection and for potentially important changes such as intestinal metaplasia. No agreed-on system is both available and prospectively shown to provide reliable estimates of the underlying pathologica...

journal_title：Human pathology

authors： El-Zimaity HM,Graham DY

更新日期：1999-01-01 00:00:00

abstract：:The present report is a neuropathologic study of three patients who died from a severe form of necrotizing encephalopathy following intrathecal methotrexate therapy and craniospinal irradiation for acute lymphoblastic leukemia. During the early phase the lesion presented as multifocal coalescing areas of coagulation n...

journal_title：Human pathology

authors： Liu HM,Maurer HS,Vongsvivut S,Conway JJ

更新日期：1978-11-01 00:00:00

abstract：:Histone methyltransferase (HMT), which catalyzes a histone methylation, is frequently altered in cancers at mutation and expression levels. The aims of this study were to explore whether SETD1B, SETDB2, and SETD2, SET domain-containing HMT genes, are mutated and expressionally altered in gastric (GC) and colorectal ca...

journal_title：Human pathology

authors： Choi YJ,Oh HR,Choi MR,Gwak M,An CH,Chung YJ,Yoo NJ,Lee SH

更新日期：2014-08-01 00:00:00

abstract：:Lymphocytic colitis (LC) and LC incomplete (LCi) are common causes of chronic watery diarrhea. The diagnosis relies on clinical findings and histopathologic evaluation. The diagnostic criteria of LC are based on hematoxylin and eosin (HE) staining. However, supplementary immunohistochemical staining for highlighting t...

journal_title：Human pathology

authors： Fiehn AK,Clausen LN,Engel U,Wildt S,Munck LK,Kristensson M,Engel PJH

更新日期：2019-02-01 00:00:00

abstract：:A 61-year-old white woman was found to have disseminated abdominal carcinoma at autopsy. The primary site proved to be a bile duct carcinoma arising from ductal epithelium of multiple von Meyenburg complexes of the liver. No other neoplastic lesion was found elsewhere after careful, gross, microscopic examination. Thi...

journal_title：Human pathology

authors： Honda N,Cobb C,Lechago J

更新日期：1986-12-01 00:00:00

abstract：:Extratubal secondary trophoblastic implants (ESTI) are a rare complication of conservative laparoscopic procedures for tubal ectopic pregnancies. These implants present with persistent beta-hCG titers postoperatively and are probably the result of disruption of the ectopic pregnancy at salpingostomy or morcellation of...

journal_title：Human pathology

authors： Doss BJ,Jacques SM,Qureshi F,Ramirez NC,Lawrence WD

更新日期：1998-02-01 00:00:00

abstract：:Epithelial inclusions in the axillary lymph nodes are very rare and have even less commonly been reported with either benign or malignant changes. We present a case of synchronous high-grade micropapillary ductal carcinoma in situ arising in the breast and in an epithelial inclusion in an ipsilateral sentinel lymph no...

journal_title：Human pathology

authors： Fitzpatrick-Swallow VL,Helin H,Cane P,Pinder SE

更新日期：2013-01-01 00:00:00

abstract：:An unusual case of acute respiratory obstruction caused by multicentric granular cell tumors of the laryngotracheobronchial tree is presented. The patient also had granular cell tumors in the tongue, vulva, and chest wall. Multiplicity of the lesions in the left lung and recurrent episodes of intercurrent pulmonary in...

journal_title：Human pathology

authors： Majmudar B,Thomas J,Gorelkin L,Symbas PN

更新日期：1981-03-01 00:00:00

abstract：:Inflammatory bowel disease-associated colorectal carcinomas (IBD-CRCs) develop in a background of chronic inflammation, and thus, the molecular landscape of these tumors likely differs from that of sporadic colorectal cancer. To add to emerging data on molecular alterations present in these tumors, we analyzed our ins...

journal_title：Human pathology

authors： Alpert L,Yassan L,Poon R,Kadri S,Niu N,Patil SA,Mujacic I,Montes D,Galbo F,Wurst MN,Zhen CJ,Cohen RD,Rubin DT,Pekow JR,Weber CR,Xiao SY,Hart J,Segal J,Setia N

更新日期：2019-07-01 00:00:00

abstract：:Sixteen cases of intermediate lymphocytic lymphoma (ILL), including eight cases with mantle zone architecture, were studied using cryostat sections, a biotin-avidin immunoperoxidase technique, and a large panel of monoclonal antibodies. The neoplastic cells invariably expressed IgM, most B lineage antigens (B1, TO15, ...

journal_title：Human pathology

authors： Strickler JG,Medeiros LJ,Copenhaver CM,Weiss LM,Warnke RA

更新日期：1988-05-01 00:00:00