Gelatinous transformation of the bone marrow.

abstract：:Geotrichum candidum was identified as an invasive organism in the terminal ileum of a man with "hairy cell" leukemia. The organism was identified on the basis of histologic and cultural characteristics. The diagnostic features of G. candidum infection are compared to those of Aspergillus and Candida species. ...

journal_title：Human pathology

authors： Jagirdar J,Geller SA,Bottone EJ

更新日期：1981-07-01 00:00:00

abstract：:Posttransplant lymphoproliferative disorder (PTLD) is associated with Epstein-Barr virus (EBV), and may clinically resemble acute allograft rejection. Three methods to show EBV in tissue were evaluated in 15 liver allograft biopsies from 12 patients including four with PTLD: (1) semiquantitative polymerase chain react...

journal_title：Human pathology

authors： Lones MA,Shintaku IP,Weiss LM,Thung SN,Nichols WS,Geller SA

更新日期：1997-05-01 00:00:00

abstract：:Three cases of veno-occlusive disease of the liver were diagnosed in four autopsied patients who had received high-dose mitomycin C therapy followed by autologous bone marrow transplantation, and the pathologic finding are reported. Review of 27 liver, examined post mortem, of patients receiving other high-dose chemot...

journal_title：Human pathology

authors： Gottfried MR,Sudilovsky O

更新日期：1982-07-01 00:00:00

abstract：:An immunohistochemical survey of X-linked inhibitor of apoptosis (XIAP) expression in mammary carcinoma was performed. XIAP, the most potent of the inhibitor of apoptosis family of caspase inhibitors, has been linked to tumor aggressiveness and therapeutic resistance in several malignancies and is considered an attrac...

journal_title：Human pathology

authors： Jaffer S,Orta L,Sunkara S,Sabo E,Burstein DE

更新日期：2007-06-01 00:00:00

abstract：:The mucin profile of 24 endoscopic biopsies of heterotopic gastric mucosa (HGM) of the upper esophagus in adults and a control group of ten cases of Meckel's diverticula containing heterotopic gastric mucosa were studied with two combined histochemical methods: alcian blue pH 2.5/PAS and high iron diamine/alcian blue ...

journal_title：Human pathology

authors： Bogomoletz WV,Geboes K,Feydy P,Nasca S,Ectors N,Rigaud C

更新日期：1988-11-01 00:00:00

abstract：:After multiple fragmentation of neoplastic nuclei into "nucleotesimals," a recently discovered variety of amitosis, some fragments appear to be inflated to full nuclear size; other probably lyse, releasing nucleic acid, which may assist in the synthesis of new cytoplasm around newly formed nuclei. This observation may...

journal_title：Human pathology

authors： Elias H,Hyde DM

更新日期：1982-07-01 00:00:00

abstract：:Basal cell carcinoma (also referred to as adenoid cystic carcinoma) is a rare tumor of the prostate. Although largely characterized as indolent, poor outcomes have been reported in a considerable fraction of cases. As yet, optimum treatment strategies for this cancer have not been developed. This study investigates pr...

journal_title：Human pathology

authors： Simper NB,Jones CL,MacLennan GT,Montironi R,Williamson SR,Osunkoya AO,Wang M,Zhang S,Grignon DJ,Eble JN,Tran T,Wang L,Baldrige LA,Cheng L

更新日期：2015-06-01 00:00:00

abstract：:B-cell chronic lymphocytic leukemia (B-CLL) consists of at least 2 subtypes with either somatically mutated or unmutated immunoglobulin heavy-chain variable region (IgVH) genes. A prognostic significance of the infiltration pattern in bone marrow trephine biopsy has been described before. The combined pattern analysis...

journal_title：Human pathology

authors： Schade U,Bock O,Vornhusen S,Jäger A,Büsche G,Lehmann U,Kreipe H

更新日期：2006-09-01 00:00:00

abstract：:Rosette-forming glioneuronal tumors of the fourth ventricle are rare brain tumors, and only 19 such lesions have been previously reported. This report presents the first case of a rosette-forming glioneuronal tumors arising from the spinal cord. A 44-year-old woman presented with a 15-year history of dissociated senso...

journal_title：Human pathology

authors： Anan M,Inoue R,Ishii K,Abe T,Fujiki M,Kobayashi H,Goya T,Nakazato Y

更新日期：2009-06-01 00:00:00

abstract：:Spindle cell carcinoma (SpCC) is uncommon, with a predilection for the upper aerodigestive tract. Its histogenesis has not been resolved, although most authors support the sarcomatoid carcinoma concept. Ploidy analysis and proliferation indices have not been reported for laryngeal SpCCs. The authors examined the patho...

journal_title：Human pathology

authors： Lewis JE,Olsen KD,Sebo TJ

更新日期：1997-06-01 00:00:00

abstract：:Clear cell sarcoma is a rare and malignant soft tissue tumor that shows phenotypic and immunohistochemical overlap with cutaneous malignant melanoma; identification of biomarkers that differentiate clear cell sarcoma from malignant melanoma is therefore needed. In this study, we performed mutation analysis of BRAF and...

journal_title：Human pathology

authors： Yang L,Chen Y,Cui T,Knösel T,Zhang Q,Geier C,Katenkamp D,Petersen I

更新日期：2012-09-01 00:00:00

abstract：:Tissues obtained from 600 routine autopsies were studied. Mineral oil lipidosis was present in the spleen (76 per cent), liver (45 per cent), bone marrow (26 per cent), and lymph nodes; more than 50 per cent of the lymph nodes from the mesentery, porta hepatis, and mediastinum were affected. Mineral oil and its metabo...

journal_title：Human pathology

authors： Cruickshank B,Thomas MJ

更新日期：1984-08-01 00:00:00

abstract：:Kaposi sarcoma-associated herpesvirus (KSHV) causes Kaposi sarcoma and is also associated with primary effusion lymphoma, a subset of diffuse large B-cell lymphomas, and multicentric Castleman disease. Because KSHV infection is endemic in sub-Saharan Africa, we sought to identify cases of KSHV-positive non-Hodgkin lym...

journal_title：Human pathology

authors： Engels EA,Mbulaiteye SM,Othieno E,Gomez M,Mathew S,Cesarman E,Knowles DM,Chadburn A

更新日期：2007-02-01 00:00:00

abstract：:We have previously shown that necrotic tumors retain their immunoreactivity for a range of cytokeratin antibodies. Some thyroid tumors undergo extensive necrosis after fine-needle aspiration (FNA) procedures. We evaluated the sensitivity of antibodies on necrotic thyroid tumors by examining a series of thyroid tumors ...

journal_title：Human pathology

authors： Judkins AR,Roberts SA,Livolsi VA

更新日期：1999-11-01 00:00:00

abstract：:The concurrent presence of JAK2 V617F, monocytosis, and bone marrow fibrosis can be observed in both chronic myelomonocytic leukemia (CMML) and primary myelofibrosis (PMF). It can be challenging to distinguish CMML with JAK2 mutation and fibrosis from other myeloid neoplasms, particularly PMF. To identify key features...

journal_title：Human pathology

authors： Hu Z,Ramos CEB,Medeiros LJ,Zhao C,Yin CC,Li S,Hu S,Wang W,Thakral B,Xu J,Verstovsek S,Lin P

更新日期：2019-03-01 00:00:00

abstract：:Current regulations require that departments of pathology have a structured and active program of quality assurance (QA) and quality improvement (QI), with the goals of enhancing patient safety, minimizing error, ensuring timely delivery of reports, and monitoring physician competence. Types of potential error may evo...

journal_title：Human pathology

authors： Association Of Directors Of Anatomic And Surgical Pathology.,Nakhleh R,Coffin C,Cooper K

更新日期：2006-08-01 00:00:00

abstract：:Twelve cases of bizarre parosteal osteochondromatous proliferation (BPOP), also known as Nora's lesion, are reported. Ten lesions were located in the small bones of the hands, and 2 were located in long bones (femur and proximal tibia). Patient age ranged from 12 to 63 years (average, 30.3 years). Radiography of the l...

journal_title：Human pathology

authors： Abramovici L,Steiner GC

更新日期：2002-12-01 00:00:00

abstract：:Primary mediastinal seminomas are unusual tumors that can present in a pure form or as part of a mixed germ cell tumor. Contrary to testicular seminomas, little is known about the expression of novel immunohistochemical markers in mediastinal seminomas. This study investigates the immunohistochemical features of these...

journal_title：Human pathology

authors： Weissferdt A,Rodriguez-Canales J,Liu H,Fujimoto J,Wistuba II,Moran CA

更新日期：2015-03-01 00:00:00

abstract：:Mammary analogue secretory carcinoma (MASC) is a recently described salivary gland tumor that has morphologic features similar to secretory carcinoma of the breast and that also harbors the same ETV6 translocation. Diffuse mammaglobin and S-100 immunoreactivity are used to differentiate MASC from its morphologic mimic...

journal_title：Human pathology

authors： Patel KR,Solomon IH,El-Mofty SK,Lewis JS Jr,Chernock RD

更新日期：2013-11-01 00:00:00

abstract：:Transitional cell (urothelial) carcinoma of the bladder is the second most common urologic malignancy and is one of the best understood neoplasms, with relatively well-defined pathogenetic pathways, natural history, and tumor biology. Conventional clinical and pathologic parameters are widely used to grade and stage t...

journal_title：Human pathology

authors： Cheng L,Zhang S,MacLennan GT,Williamson SR,Lopez-Beltran A,Montironi R

更新日期：2011-04-01 00:00:00

abstract：:Immunofluorescent staining of tissue from a lung tumor detected 12 years after excision of a primary malignant melanoma of the skin was negative for prekeratin and positive for vimentin, indicating that the tumor was not epithelial in origin and excluding carcinoma from the differential diagnosis. Complementary conven...

journal_title：Human pathology

authors： Huszar M,Halkin H,Herczeg E,Bubis J,Geiger B

更新日期：1983-11-01 00:00:00

abstract：:We report two cases of allergic bronchopulmonary fungal disease (ABPFD) caused by Curvularia sp and associated with allergic fungal sinusitis (AFS). Curvularia lunata was cultured in one case and Curvularia senegalensis was cultured in the other. Based on these cases and a review of the literature, we discuss unusual ...

journal_title：Human pathology

authors： Travis WD,Kwon-Chung KJ,Kleiner DE,Geber A,Lawson W,Pass HI,Henderson D

更新日期：1991-12-01 00:00:00

abstract：:Esophageal and colorectal adenocarcinomas overexpress Fas ligand (FasL), which can protect them from immune surveillance. The aim of this work was to determine whether FasL expression, and therefore FasL-dependent immune evasion, occurs early during malignant transformation in Barrett's metaplasia (BM) of the esophagu...

journal_title：Human pathology

authors： Younes M,Schwartz MR,Finnie D,Younes A

更新日期：1999-11-01 00:00:00

abstract：:Previously used only as a screening tool, cytology now emerges as a powerful diagnostic technique, especially since the advent of the fine needle aspiration (FNA) biopsy. This article highlights the use of ancillary techniques, primarily electron microscopy (EM), and immunohistochemistry (IHC). When coupled with routi...

journal_title：Human pathology

authors： Turbat-Herrera EA,Knowles K

更新日期：1998-12-01 00:00:00

abstract：:Partial monosomy 13q, a chromosomal alteration originally reported in spindle cell lipoma, has also been documented in a few cases of mammary myofibroblastoma. Subsequently, a monoallelic loss of RB1 and FOXO1, located on 13q14, was identified in some cases of cellular angiofibroma, a benign stromal tumor of the lower...

journal_title：Human pathology

authors： Magro G,Righi A,Casorzo L,Antonietta T,Salvatorelli L,Kacerovská D,Kazakov D,Michal M

更新日期：2012-11-01 00:00:00

abstract：:We have previously reported that the drs gene has the ability to suppress transformation by v-src and v-K-ras in the rat cell line F2808. We have also shown that the expression of drs mRNA is markedly reduced in a variety of human cancer cell lines, suggesting that down-regulation of drs mRNA is correlated with the de...

journal_title：Human pathology

authors： Kim CJ,Shimakage M,Kushima R,Mukaisho K,Shinka T,Okada Y,Inoue H

更新日期：2003-07-01 00:00:00

abstract：:The use of interleukin-2 (IL-2), either alone or in combination with lymphokine-activated killer cells, tumor infiltrating lymphocytes, or other immunotherapeutic agents has added a new list of alternatives to conventional antineoplastic regimens. Little information is available about the pathologic changes occurring ...

journal_title：Human pathology

authors： Kragel AH,Travis WD,Feinberg L,Pittaluga S,Striker LM,Roberts WC,Lotze MT,Yang JJ,Rosenberg SA

更新日期：1990-05-01 00:00:00

abstract：:The pathology of cytomegalovirus (CMV) encephalitis was studied at autopsy in thirty patients with acquired immunodeficiency syndrome. Lesions could be segregated into five major categories: microglial nodules, isolated inclusion-bearing cells, focal parenchymal necrosis, necrotizing ventriculo-encephalitis, and necro...

journal_title：Human pathology

authors： Morgello S,Cho ES,Nielsen S,Devinsky O,Petito CK

更新日期：1987-03-01 00:00:00

abstract：:The clinical spectrum of coronavirus disease 2019 is getting wider with the exponential increase of patients worldwide. Initially described with flu-like symptoms, variable cutaneous manifestations have been reported, with only few histopathological descriptions. Detection of the virus in cutaneous samples has been as...

journal_title：Human pathology

authors： Fattori A,Cribier B,Chenard MP,Mitcov M,Mayeur S,Weingertner N

更新日期：2021-01-01 00:00:00

abstract：:Patients with small cell lung carcinoma (SCLC) rarely demonstrate long-term survival. We previously reported that gene expression profiling identified a subset of SCLC with good prognosis in surgical cases. To find an easier way to routinely identify SCLC belonging to this subset, we conducted the present study with a...

journal_title：Human pathology

authors： Hamanaka W,Motoi N,Ishikawa S,Ushijima M,Inamura K,Hatano S,Uehara H,Okumura S,Nakagawa K,Nishio M,Horai T,Aburatani H,Matsuura M,Iwasaki A,Ishikawa Y

更新日期：2014-05-01 00:00:00