Primary mediastinal seminomas: a comprehensive immunohistochemical study with a focus on novel markers.

abstract：:Hepatic artery thrombosis (HAT) following orthotopic liver transplantation (OLT) can cause hepatic parenchymal necrosis and ischemic cholangiopathy. This study investigates additional histologic features that may suggest HAT in post-OLT liver specimens. For 94 liver specimens (explanted allografts and biopsies) from p...

journal_title：Human pathology

authors： Lee M,Agostini-Vulaj D,Gonzalez RS

更新日期：2019-08-01 00:00:00

abstract：:Patients with small cell lung carcinoma (SCLC) rarely demonstrate long-term survival. We previously reported that gene expression profiling identified a subset of SCLC with good prognosis in surgical cases. To find an easier way to routinely identify SCLC belonging to this subset, we conducted the present study with a...

journal_title：Human pathology

authors： Hamanaka W,Motoi N,Ishikawa S,Ushijima M,Inamura K,Hatano S,Uehara H,Okumura S,Nakagawa K,Nishio M,Horai T,Aburatani H,Matsuura M,Iwasaki A,Ishikawa Y

更新日期：2014-05-01 00:00:00

abstract：:The aim of this study was to systematically investigate clinicopathologic features of the recently described pancreatic acinar-like adenocarcinoma of the proximal stomach invading the esophagus (n = 43). Patient median age was 66 years (range, 51-90 years). The male-to-female ratio was 7.6. Grossly, pancreatic acinar-...

journal_title：Human pathology

authors： Huang Q,Gold JS,Shi J,Fan X,Wu H,Feng A,Zhou Q

更新日期：2012-06-01 00:00:00

abstract：:Histological criteria for the diagnosis of reflux esophagitis include basal zone hyperplasia, stromal papillae elongation, and inflammatory infiltrate. However, endoscopic esophageal biopsy specimens may include little or no lamina propria. Intraepithelial T lymphocytes, seen in hematoxylin and eosin-stained sections ...

journal_title：Human pathology

authors： Esposito S,Valente G,Zavallone A,Guidali P,Rapa A,Oderda G

更新日期：2004-01-01 00:00:00

abstract：:Fetal vessels in the placentas of 11 of 15 infants with cerebral palsy contained thrombi. An alternate basis for the injury was identified in the four placentas without thrombi. Autopsy findings in one infant who died at age 1 month confirmed the presence of cerebral thrombi and infarcts. It is concluded that thrombot...

journal_title：Human pathology

authors： Kraus FT

更新日期：1997-02-01 00:00:00

abstract：:Three ovarian thecomas were studied by ultrastructural and immunohistochemical techniques. In each tumor, a small number of tumor cells stained for estradiol. Vacuolated as well as plump non-vacuolated tumor cells were positive, but spindle-shaped cells were negative. Ultrastructural examination showed two principle c...

journal_title：Human pathology

authors： Gaffney EF,Majmudar B,Hewan-Lowe K

更新日期：1984-02-01 00:00:00

abstract：:Fluorescence in situ hybridization, loss of heterozygosity testing, and comparative genomic hybridization have been used to detect NF2 gene alterations in both sporadic and neurofibromatosis type 2 (NF2)-associated central nervous system tumors. In this study, we performed chromogenic in situ hybridization (CISH) and ...

journal_title：Human pathology

authors： Begnami MD,Palau M,Rushing EJ,Santi M,Quezado M

更新日期：2007-09-01 00:00:00

abstract：:Kaposi sarcoma-associated herpesvirus (KSHV) causes Kaposi sarcoma and is also associated with primary effusion lymphoma, a subset of diffuse large B-cell lymphomas, and multicentric Castleman disease. Because KSHV infection is endemic in sub-Saharan Africa, we sought to identify cases of KSHV-positive non-Hodgkin lym...

journal_title：Human pathology

authors： Engels EA,Mbulaiteye SM,Othieno E,Gomez M,Mathew S,Cesarman E,Knowles DM,Chadburn A

更新日期：2007-02-01 00:00:00

abstract：:The case of an infant with the clinical features of bronchopulmonary dysplasia but with pathologic features unlike those usually associated with this condition is reported. The condition of this infant was probably related to respiratory therapy and may have been a variant of bronchopulmonary dysplasia. ...

journal_title：Human pathology

authors： McKay CA Jr,Faulkner CS 2nd,Edwards WH

更新日期：1985-06-01 00:00:00

abstract：:This study aimed to determine the correlations of 7 histopathologic prognostic indicators of follicular lymphoma (follicular lymphoma grade, CD10 expression, Bcl-2 expression, IGH/BCL2 fusion, diffuse area, fibrosis, and marginal zone differentiation) with progression-free survival, overall survival, and follicular ly...

journal_title：Human pathology

authors： Maeshima AM,Taniguchi H,Nomoto J,Miyamoto K,Fukuhara S,Munakata W,Maruyama D,Kim SW,Watanabe T,Kobayashi Y,Tobinai K,Tsuda H

更新日期：2013-11-01 00:00:00

abstract：:Paracoccidioidomycosis is a systemic mycosis with a geographic distribution that is limited to Central and South America; Brazil has the highest number of cases. Severe disseminated disease caused by paracoccidioidomycosis was observed in acquired immunodeficiency syndrome patients who live or have resided in endemic ...

journal_title：Human pathology

authors： de Freitas RS,Dantas KC,Garcia RS,Magri MM,de Andrade HF Jr

更新日期：2010-09-01 00:00:00

abstract：:To assess the proliferative activity of renal cell carcinoma (RCC-A) in patients with acquired cystic disease of the kidney (ACDK) after long-term hemodialysis, we analyzed cell cycle, DNA ploidy, and S-phase fraction by flow cytometry (FCM) and proliferating cell nuclear antigen (PCNA) labeling index by immunohistoch...

journal_title：Human pathology

authors： Ikeda R,Tanaka T,Moriyama MT,Kawamura K,Miyazawa K,Suzuki K

更新日期：2002-02-01 00:00:00

abstract：:Neuronal intranuclear inclusion disease (NIID) is a progressive, usually fatal degenerative neurologic condition characterized by eosinophilic, intranuclear inclusions in neurons of the central and peripheral nervous system. We report a boy with onset of disease manifestations at age 3 and death at age 9, who showed c...

journal_title：Human pathology

authors： Oyer CE,Cortez S,O'Shea P,Popovic M

更新日期：1991-07-01 00:00:00

abstract：:Prior studies have suggested that the type of breast cancer influences the location of distant metastases ("organotropism") and that there may be discordance of estrogen receptor and human epidermal growth factor receptor 2 (Her2) expression between primaries and metastases. Our aims were to investigate the relationsh...

journal_title：Human pathology

authors： St Romain P,Madan R,Tawfik OW,Damjanov I,Fan F

更新日期：2012-03-01 00:00:00

abstract：:Micropapillary carcinoma of the breast is associated with increased rates of lymph node metastasis and lymphovascular invasion. While activating point mutations in PIK3CA (encoding phosphatidylinositol-3-kinase catalytic subunit) or AKT1 are found in 25% to 30% of invasive ductal carcinomas, the mutational profile of ...

journal_title：Human pathology

authors： Flatley E,Ang D,Warrick A,Beadling C,Corless CL,Troxell ML

更新日期：2013-07-01 00:00:00

abstract：:Because infants rarely suffer coronary artery thrombosis, it is mistakenly assumed that they seldom have significant ischemic myocardial injury. However, ischemic myocardial necrosis (INM) is common in the papillary muscles and subendocardium of stressed newborns and other infants. Standard dissection methods encourag...

journal_title：Human pathology

authors： Donnelly WH,Hawkins H

更新日期：1987-01-01 00:00:00

abstract：:We investigated whether histological chorioamnionitis (HCA) is a risk factor predisposing to leukemoid reaction (LR) and whether LR is associated with the preterm parturition syndrome and the systemic fetal inflammation response syndrome. A prospective histological study on placentas was performed in preterm infants (...

journal_title：Human pathology

authors： Zanardo V,Vedovato S,Trevisanuto DD,Suppiej A,Cosmi E,Fais GF,Chiarelli S

更新日期：2006-01-01 00:00:00

abstract：:Clinicopathologic records and neuropathologic tissues of 109 patients who underwent necropsy after treatment with bone marrow transplantation (BMT) were examined. Underlying disorders included leukemia (70), aplastic anemia (25), solid tumors (7), lymphoma (5), Hodgkin's disease (1) and Wiskott-Aldrich syndrome (1). T...

journal_title：Human pathology

authors： Mohrmann RL,Mah V,Vinters HV

更新日期：1990-06-01 00:00:00

abstract：:Previous studies indicated that microRNA (miR)-675 and its precursor lncRNA H19 were both overexpressed in glioma tissues, and H19 might play an oncogenic role. To investigate the involvement of miR-675 in gliomas and its underlying mechanisms, we here collected candidate target genes of miR-675-5p from miRTarBase (ht...

journal_title：Human pathology

authors： Zheng Y,Lu X,Xu L,Chen Z,Li Q,Yuan J

更新日期：2017-11-01 00:00:00

abstract：:As a result of major recent advances in understanding the biology of gastrointestinal stromal tumors (GISTs), specifically recognition of the central role of activating KIT mutations and associated KIT protein expression in these lesions, and the development of novel and effective therapy for GISTs using the receptor ...

journal_title：Human pathology

authors： Fletcher CD,Berman JJ,Corless C,Gorstein F,Lasota J,Longley BJ,Miettinen M,O'Leary TJ,Remotti H,Rubin BP,Shmookler B,Sobin LH,Weiss SW

更新日期：2002-05-01 00:00:00

abstract：:Galectins, a family of beta-galactoside-binding animal lectins, might be involved in tumor progression. In this study, the expression patterns of galectin-1 and -3 were examined immunohistochemically in intrahepatic cholangiocarcinoma (ICC), with emphasis on its development and progression as well as its histopatholog...

journal_title：Human pathology

authors： Shimonishi T,Miyazaki K,Kono N,Sabit H,Tuneyama K,Harada K,Hirabayashi J,Kasai K,Nakanuma Y

更新日期：2001-03-01 00:00:00

abstract：:Most histopathologic descriptions of influenza pneumonia are based on autopsy findings in fatal cases during epidemics and pandemics of influenza. We describe the histologic findings of influenza pneumonia observed in biopsy material derived from six sporadic cases of influenza (influenza A, four cases; influenza B, o...

journal_title：Human pathology

authors： Yeldandi AV,Colby TV

更新日期：1994-01-01 00:00:00

abstract：:Kikuchi's histiocytic necrotizing lymphadenitis is a self-limited disorder that typically involves the cervical lymph nodes of young women. Although a viral etiology has been postulated, a definitive viral agent has not been identified. Recent reports have suggested that human herpesvirus 8 (HHV 8) or Epstein-Barr vir...

journal_title：Human pathology

authors： George TI,Jones CD,Zehnder JL,Warnke RA,Dorfman RF

更新日期：2003-02-01 00:00:00

abstract：:Endothelial cell injury may contribute to the progression of various glomerular diseases. In the present study, we examined glomerular capillary injury in acute and chronic glomerular lesions in patients with Immunoglobulin A nephropathy (IgAN). We selected renal biopsy samples of IgAN (n = 200), and glomerular capill...

journal_title：Human pathology

authors： Kusano T,Takano H,Kang D,Nagahama K,Aoki M,Morita M,Kaneko T,Tsuruoka S,Shimizu A

更新日期：2016-03-01 00:00:00

abstract：:Fifty-three surgically resected small cell carcinomas of the lung were studied morphometrically, electron microscopically, immunohistochemically, and in terms of possible site of origin. Four subtypes of small cell carcinomas were identified: oat cell carcinoma (OAT), small cell carcinoma of the intermediate cell type...

journal_title：Human pathology

authors： Nomori H,Shimosato Y,Kodama T,Morinaga S,Nakajima T,Watanabe S

更新日期：1986-06-01 00:00:00

abstract：:In this study, we aimed to identify whether tumor budding is associated with the progression and prognosis of oral squamous cell carcinoma (OSCC) and investigate the correlation between tumor budding and regulators of epithelial-mesenchymal transition (EMT). Fifty-six cases of OSCC were selected and their tumor buddin...

journal_title：Human pathology

authors： Hong KO,Oh KY,Shin WJ,Yoon HJ,Lee JI,Hong SD

更新日期：2018-10-01 00:00:00

abstract：:A 61-year-old white woman was found to have disseminated abdominal carcinoma at autopsy. The primary site proved to be a bile duct carcinoma arising from ductal epithelium of multiple von Meyenburg complexes of the liver. No other neoplastic lesion was found elsewhere after careful, gross, microscopic examination. Thi...

journal_title：Human pathology

authors： Honda N,Cobb C,Lechago J

更新日期：1986-12-01 00:00:00

abstract：:Seminoma and sarcoidosis do not seem to be associated diseases, judging from epidemiologic data. The presence of these two diseases in the patient whose case is reported may have been coincidental. It was observed, however, that when the testis tumor appeared in this patient, the longstanding sarcoid lesions significa...

journal_title：Human pathology

authors： Colebunders R,Bultinck J,Servais J,Denis L

更新日期：1984-04-01 00:00:00

abstract：:The previously unreported association of granulomatous gastritis and mononeuritis multiplex occurring in the setting of a vasculitic syndrome is described. The two conditions are considered to be associated and to be immune mediated. The previously accepted concept of isolated granulomatous gastritis is disputed. ...

journal_title：Human pathology

authors： O'Donovan C,Murray J,Staunton H,Doyle JS,Leader M

更新日期：1991-10-01 00:00:00

abstract：:Among women in Taiwan, thyroid cancer is the fifth most common malignant neoplasia. However, genomic profiling of papillary thyroid cancer (PTC) cases from Taiwan has not been attempted previously. We used whole-exome sequencing to identify mutations in a cohort of 19 PTC patients. Sequencing was performed using the I...

journal_title：Human pathology

authors： Chang CC,Chang YS,Huang HY,Yeh KT,Liu TC,Chang JG

更新日期：2018-08-01 00:00:00