Expression of endogenous galectin-1 and galectin-3 in intrahepatic cholangiocarcinoma.

abstract：:Two undifferentiated (embryonal) sarcomas of liver were studied ultrastructurally and immunohistochemically. Electron microscopic examination of the pleomorphic tumor cells revealed fibroblastic and histiocytic characteristics. There were no specific findings to support rhabdomyoblastic, leiomyoblastic, or epithelial ...

journal_title：Human pathology

authors： Keating S,Taylor GP

更新日期：1985-07-01 00:00:00

abstract：:GATA3 immunostaining is a sensitive marker for mammary and urothelial carcinomas. It is routinely used in surgical pathology during workup of carcinomas of unknown origin. To the best of our knowledge, this is the first focused study of GATA3 expression in gallbladder adenocarcinomas. In this study, we evaluated GATA3...

journal_title：Human pathology

authors： Guo W,Lee W,Lu Y,Li X,Chandan VS

更新日期：2020-12-01 00:00:00

abstract：:Hepatoid adenocarcinoma is an extrahepatic tumor characterized by morphological similarities to hepatocellular carcinoma. The lesions contain a tubular adenocarcinoma that seems to develop "hepatoid" features, but the relation between the tubular adenocarcinomatous and the hepatoid components remains unclear. We compa...

journal_title：Human pathology

authors： Kumashiro Y,Yao T,Aishima S,Hirahashi M,Nishiyama K,Yamada T,Takayanagi R,Tsuneyoshi M

更新日期：2007-06-01 00:00:00

abstract：:Granulocyte alloantibodies and autoantibodies have a key role in the pathophysiology of several clinical problems. These include febrile transfusion reactions, severe pulmonary reactions to transfusion, isoimmune neonatal neutropenia, failure of effective granulocyte transfusion, autoimmune neutropenia, drug-induced n...

journal_title：Human pathology

authors： McCullough J

更新日期：1983-03-01 00:00:00

abstract：:Inflammatory pseudotumors (IPs), mostly benign lesions characterized by fibrotic ground tissue and polyclonal mononuclear infiltrate, may affect all organ systems. IPs originating in the central nervous system (IP-CNS) are very rare, and their distinct histopathologic features are poorly characterized. Three otherwise...

journal_title：Human pathology

authors： Häusler M,Schaade L,Ramaekers VT,Doenges M,Heimann G,Sellhaus B

更新日期：2003-03-01 00:00:00

abstract：:Myocardial apoptosis has previously been observed in human acute myocardial infarcts. We examined the time of appearance and extent of apoptosis in human acute myocardial infarcts, and compared these with necrotic cell death. Because nuclear internucleosomal DNA fragmentation is a hallmark of apoptosis, autopsied tiss...

journal_title：Human pathology

authors： Veinot JP,Gattinger DA,Fliss H

更新日期：1997-04-01 00:00:00

abstract：:Although rare, synovial sarcoma (SS) is one of the most common soft tissue sarcomas affecting young adults. To investigate potential tumor markers related to synovial sarcoma prognosis, we carried out a single-institution retrospective analysis of 103 patients diagnosed with SS between 1980 and 2009. Clinical outcome ...

journal_title：Human pathology

authors： Charbonneau B,Vogel RI,Manivel JC,Rizzardi A,Schmechel SC,Ognjanovic S,Subramanian S,Largaespada D,Weigel B

更新日期：2013-09-01 00:00:00

abstract：:The diagnosis of microscopic colitis (MC) relies on specific histopathological findings in colon biopsies. The number of biopsies needed to diagnose MC remains disputed. The aim of the study was to determine the number and site of biopsies necessary for the diagnosis and the effect of perpendicular orientation when em...

journal_title：Human pathology

authors： Kanstrup Fiehn AM,Heiberg Engel PJ,Lanzarotto F,Goudkade D,Landolfi S,Munck LK,Villanacci V

更新日期：2020-09-01 00:00:00

abstract：:Nuclear pore complexes (NPCs) are elaborate macromolecular structures that regulate the bidirectional nucleocytoplasmic traffic system. In vertebrate cells, NPCs include a family of 50 to 100 proteins termed nucleoporins (Nups). The 88-kD Nup has been found to be linked in a dynamic subcomplex with the oncogenic CAN/N...

journal_title：Human pathology

authors： Gould VE,Orucevic A,Zentgraf H,Gattuso P,Martinez N,Alonso A

更新日期：2002-05-01 00:00:00

abstract：:Four cases of radiation cystitis that caused diagnostic difficulty because of an epithelial proliferation with architectural complexity and reactive cytologic atypia are described. The patients, 2 male, 2 female, were from 43 to 77 years of age. Two presented with hematuria. Cystoscopy disclosed abnormalities in 3 pat...

journal_title：Human pathology

authors： Baker PM,Young RH

更新日期：2000-06-01 00:00:00

abstract：:A case of clear cell sarcoma of tendons and aponeuroses arising in the elbow of a young woman is reported. Local recurrence and lymph node metastases occurred despite radiation therapy, chemotherapy, and amputation of the right arm, and the patient died of the tumor approximately ten months after the initial diagnosis...

journal_title：Human pathology

authors： Azumi N,Turner RR

更新日期：1983-12-01 00:00:00

abstract：:We report the clinical, histologic, and genetic findings of concurrent neuroblastoma and nephroblastoma in an infant with Fanconi's anemia (FA). Both tumors had characteristic chromosomal aberrations. In particular, the neuroblastoma showed a gain of chromosome 17q, considered an important factor for prognosis. But un...

journal_title：Human pathology

authors： Bissig H,Staehelin F,Tolnay M,Avoledo P,Richter J,Betts D,Bruder E,Kühne T

更新日期：2002-10-01 00:00:00

abstract：:In this autopsy series of cryptococcal meningoencephalitis (CME), the authors analyzed neuropathologic lesions in 13 human immunodeficiency virus (HIV) and 14 non-HIV-related cases. Most non-HIV patients did not have immunosuppressive predisposing illness. Analysis of pathological findings revealed significant differe...

journal_title：Human pathology

authors： Lee SC,Dickson DW,Casadevall A

更新日期：1996-08-01 00:00:00

abstract：:Dermatofibrosarcoma protuberans is genetically characterized by the translocation t(17;22)(q22;q13) resulting in the PDGFB/COL1A1 fusion gene. Fluorescence in situ hybridization with specific probes enables a rapid detection of this gene. In this study, the presence of the translocation t(17;22)(q22;q13) by fluorescen...

journal_title：Human pathology

authors： Segura S,Salgado R,Toll A,Martín-Ezquerra G,Yébenes M,Sáez A,Solé F,Barranco C,Umbert P,Espinet B,Pujol RM

更新日期：2011-02-01 00:00:00

abstract：:Histologic prognostic parameters in papillary renal cell carcinoma (PRCC) are unclear. The aims were to review the clinicopathological features of PRCC, including Fuhrman grade and International Society of Urological Pathology (ISUP) nucleolar grade, and to identify parameters that may be independent prognostic indica...

journal_title：Human pathology

authors： Cornejo KM,Dong F,Zhou AG,Wu CL,Young RH,Braaten K,Sadow PM,Nielsen GP,Oliva E

更新日期：2015-10-01 00:00:00

abstract：:Sox2 is a key transcription factor for embryonic development and plays a critical role in determining the fate of stem cells. Recently, Sox2 has been detected in several human tumors, indicating a potential function in tumorigenesis. We initially reported remarkably increased nuclear Sox2 staining in cervical carcinom...

journal_title：Human pathology

authors： Ji J,Zheng PS

更新日期：2010-10-01 00:00:00

abstract：:Basal cell proliferation is a common finding in a benign hyperplastic prostate gland. Occasionally, basal cell hyperplasia is so florid that it can be mistaken for prostatic adenocarcinoma. We characterized histological, ultrastructural, and immunohistochemical features of florid basal cell hyperplasia from transureth...

journal_title：Human pathology

authors： Yang XJ,Tretiakova MS,Sengupta E,Gong C,Jiang Z

更新日期：2003-05-01 00:00:00

abstract：:Natural killer (NK)/T-cell lymphomas represent a rare type of lymphoma derived from either activated NK cells or, rarely, cytotoxic T cells. These lesions are most commonly extranodal and tend to present as destructive lesions within the midline facial structures. Other than the nasal cavity and paranasal sinuses, sev...

journal_title：Human pathology

authors： Kaluza V,Rao DS,Said JW,de Vos S

更新日期：2006-06-01 00:00:00

abstract：:Histone methyltransferase (HMT), which catalyzes a histone methylation, is frequently altered in cancers at mutation and expression levels. The aims of this study were to explore whether SETD1B, SETDB2, and SETD2, SET domain-containing HMT genes, are mutated and expressionally altered in gastric (GC) and colorectal ca...

journal_title：Human pathology

authors： Choi YJ,Oh HR,Choi MR,Gwak M,An CH,Chung YJ,Yoo NJ,Lee SH

更新日期：2014-08-01 00:00:00

abstract：:It is currently thought that most clear cell and endometrioid carcinomas arise from ovarian endometriosis. We recently suggested that, besides their origin in the ovary, reduction of CDC42 messenger RNA (a member of the RHO GTPase family) may contribute to explain why clear cell carcinomas are not uncommonly found lim...

journal_title：Human pathology

authors： Canet B,Pons C,Espinosa I,Prat J

更新日期：2012-05-01 00:00:00

abstract：:Immunoreactivity to LN2 and LN3, monoclonal antibodies that recognize components of the class II major histocompatibility complex, was assessed in 72 cases of non-small cell lung carcinoma (NSCLC) (32 biopsy specimens, 40 resection specimens) and 64 cases of small cell carcinoma (56 biopsy specimens, 8 resections) of ...

journal_title：Human pathology

authors： Hua ZX,Tanaka KE,Tazelaar HD,Myers J,Markowitz GS,Borczuk AC

更新日期：1998-12-01 00:00:00

abstract：:Grade Group (GG) 4 prostate cancer includes Gleason scores (GS) 3 + 5 = 8, 4 + 4 = 8, and 5 + 3 = 8. Some studies without pathology re-review of historical cohorts proposed that the presence of pattern 5 worsens prognosis compared to GS 4 + 4 = 8 cancer. We assessed how often historically graded GS 5 + 3 = 8 cancers r...

journal_title：Human pathology

authors： Kryvenko ON,Williamson SR,Schwartz LE,Epstein JI

更新日期：2020-03-01 00:00:00

abstract：:A comparative study of the immunohistochemical (Stem cell leukemia/T-cell acute leukemia [SCL/TAL-1] protein expression) and genotypic (deletions in the SCL/tal-1 gene) findings in T-acute lymphoblastic leukemia (T-ALL) is presented. Formalin-fixed tissue from 50 cases of T-ALL were stained with a novel monoclonal ant...

journal_title：Human pathology

authors： Chetty R,Pulford K,Jones M,Mathieu-Mahul D,Close P,Hussein S,Pallesen G,Ralfkiaer E,Stein H,Gatter K

更新日期：1995-09-01 00:00:00

abstract：:Although tumors involving the bladder and ureter have been well described, there are only few studies in the pathology literature specifically analyzing tumors involving the ureteral orifice (UO). A search was performed for biopsy and resection specimens (transurethral resection, radical cystectomy/cystoprostatectomy,...

journal_title：Human pathology

authors： Annan AC,Stevens KA,Osunkoya AO

更新日期：2017-07-01 00:00:00

abstract：:Hyalinizing clear cell carcinoma (HCCC) has only been described in salivary glands of the head and neck. We report a 38-year-old man with a 2.6-cm lung tumor that was growing in a peribronchial location and had morphologic features of HCCC. The tumor cells expressed cytokeratin 7 and keratin AE1/AE3, and the vast majo...

journal_title：Human pathology

authors： García JJ,Jin L,Jackson SB,Larsen BT,Lewis JE,Sukov WR,Roden AC

更新日期：2015-03-01 00:00:00

abstract：:We have previously reported that the drs gene has the ability to suppress transformation by v-src and v-K-ras in the rat cell line F2808. We have also shown that the expression of drs mRNA is markedly reduced in a variety of human cancer cell lines, suggesting that down-regulation of drs mRNA is correlated with the de...

journal_title：Human pathology

authors： Kim CJ,Shimakage M,Kushima R,Mukaisho K,Shinka T,Okada Y,Inoue H

更新日期：2003-07-01 00:00:00

abstract：:The DNA content of both fresh and formalin-fixed, paraffin-embedded tissues from 30 solid neoplasms was analyzed by flow cytometry. Cells from a single paraffin block of each tumor were disaggregated according to the method of Hedley et al. Cells were sampled from multiple sites of each fresh specimen. Fresh and depar...

journal_title：Human pathology

authors： Frierson HF Jr

更新日期：1988-03-01 00:00:00

abstract：:Angiocentric immunoproliferative lesions (AILs) are believed to represent a unique type of extranodal malignant lymphoma on the basis of clinicopathologic and immunophenotypic evidence. However, molecular studies to assess clonality have been performed on a small number of cases. In this study we assessed the clonalit...

journal_title：Human pathology

authors： Medeiros LJ,Peiper SC,Elwood L,Yano T,Raffeld M,Jaffe ES

更新日期：1991-11-01 00:00:00

abstract：:Lipomatous lesions of the heart involving the atria and interatrial septum are not well known. Most such lesions do not become clinically significant; however, intractable arrhythmias, blood flow obstruction, and valvular disruption may result from extensive fatty infiltration of the atrial wall or from the mass effec...

journal_title：Human pathology

authors： Cunningham KS,Veinot JP,Feindel CM,Butany J

更新日期：2006-10-01 00:00:00

abstract：:This report concerns a young woman who, after taking a contraceptive preparation orally for three years, developed the Budd-Chiari syndrome as the result of a widespread chronic obliterative process involving the intrahepatic efferent venous system. Her prolonged course, which failed to respond to an end-to-side porta...

journal_title：Human pathology

authors： Alpert LI

更新日期：1976-11-01 00:00:00