Bile duct carcinoma associated with multiple von Meyenburg complexes in the liver.

abstract：:Loss or reduced expression of E-cadherin has been shown to be associated with poor survival in patients with bladder cancer. In numerous cases, loss of E-cadherin expression in bladder tumors has been accompanied by continued association of catenins with the membrane, suggestive of the expression of an alternative cad...

journal_title：Human pathology

authors： Rieger-Christ KM,Cain JW,Braasch JW,Dugan JM,Silverman ML,Bouyounes B,Libertino JA,Summerhayes IC

更新日期：2001-01-01 00:00:00

abstract：:We investigated the use of remote video microscopy (telepathology) to assist in the diagnosis of 52 neurosurgical frozen section cases. The TelMed system (Discovery Medical Systems, Overland Park, KS), in which the referring pathologist selects appropriate fields for transmission to the consultant, was used for the st...

journal_title：Human pathology

authors： Becker RL Jr,Specht CS,Jones R,Rueda-Pedraza ME,O'Leary TJ

更新日期：1993-08-01 00:00:00

abstract：:Two cases of lymphadenopathy resulting from a lymph node foreign body reaction to silicone are presented. In each case lymph node biopsy was performed because of the clinical suspicion of neoplastic disease. Histologic study in both cases revealed no evidence of malignant disease, but rather demonstrated multinucleate...

journal_title：Human pathology

authors： Kircher T

更新日期：1980-05-01 00:00:00

abstract：:Follicular lymphoma with MYC and BCL2 translocations, so-called double-hit follicular lymphoma (DH-FL), is rare. Here, we report the clinicopathological features of 7 cases of DH-FL. All neoplasms had a follicular pattern (1 partially diffuse). Five cases were predominantly low grade, 4 of which had focal (≤20%) grade...

journal_title：Human pathology

authors： Miao Y,Hu S,Lu X,Li S,Wang W,Medeiros LJ,Lin P

更新日期：2016-12-01 00:00:00

abstract：:Sessile serrated adenomas and traditional serrated adenomas are pathogenetically related to inhibition of apoptosis. Survivin and hedgehog proteins, including sonic hedgehog, patched, and smoothened, inhibit apoptosis, with hedgehog proteins forming a signal transduction cascade implicated in digestive cancers. This s...

journal_title：Human pathology

authors： Parfitt JR,Driman DK

更新日期：2007-05-01 00:00:00

abstract：:We report novel renal histopathologic features in a patient with hemolytic uremic syndrome after allogeneic bone marrow transplantation who survived with plasma exchange therapy. This distribution of vascular lesions within the kidney differed from previously described cases, which were uniformly fatal, in that there ...

journal_title：Human pathology

authors： Arends MJ,Harrison DJ

更新日期：1989-01-01 00:00:00

abstract：:A better knowledge of the biological aggressiveness of individual tumors could facilitate the selection of treatment in prostate cancer patients. This study assesses the influence of histological and molecular features in core needle biopsy specimens of prostate cancer on tumor-specific survival. Formalin-fixed core n...

journal_title：Human pathology

authors： Bubendorf L,Tapia C,Gasser TC,Casella R,Grunder B,Moch H,Mihatsch MJ,Sauter G

更新日期：1998-09-01 00:00:00

abstract：:Schistosoma haematobium infection is a common occurrence in Africa and the Middle East and is the world's leading cause of hematuria. Since more North Americans are venturing into endemic areas and more residents of endemic areas are seeking medical care in North America, pathologists must be able not only to diagnose...

journal_title：Human pathology

authors： Smith JH,Christie JD

更新日期：1986-04-01 00:00:00

abstract：:Primary renal collision tumors composed of 2 histologically distinct components are rare with only isolated case reports in the medical literature. Oncocytoma is a benign renal neoplasm, which is thought to originate from distal tubular epithelial cells. Mucinous tubular and spindle cell carcinoma (MTSCC) of kidney is...

journal_title：Human pathology

authors： Arora K,Miller R,Mullick S,Shen S,Ayala AG,Ro JY

更新日期：2018-01-01 00:00:00

abstract：:The case of a 65-year-old female patient with a pedunculated left atrial angiosarcoma is presented. Histologically, the tumor was composed of vascular spaces lined by atypical cells with similar cells in the solid portion of the tumor. Immunohistochemical stain for factor VIII-related antigen was positive in the cells...

journal_title：Human pathology

authors： Keohane ME,Lazzam C,Halperin JL,Strauchen JA,Ergin MA

更新日期：1989-06-01 00:00:00

abstract：:Malignant mixed tumors of the parotid gland are rare. Metastasizing lesions are even more rare. To the best of our knowledge, this is the first case reported in the English literature in which the scalp nodule was the primary manifestation of the malignant nature of the parotid tumor. ...

journal_title：Human pathology

authors： Giltman L,Alderete M,Minkowitz S

更新日期：1977-11-01 00:00:00

abstract：:Neuronal intranuclear inclusion disease (NIID) is a progressive, usually fatal degenerative neurologic condition characterized by eosinophilic, intranuclear inclusions in neurons of the central and peripheral nervous system. We report a boy with onset of disease manifestations at age 3 and death at age 9, who showed c...

journal_title：Human pathology

authors： Oyer CE,Cortez S,O'Shea P,Popovic M

更新日期：1991-07-01 00:00:00

abstract：:Three cases of giant cell carcinoma of lung and six other lung carcinomas with large atypical cell formation were studied by both light and electron microscopy. The giant cell carcinomas showed unique light and electron microscopic features, whereas large atypical cells from other lung carcinomas usually retained some...

journal_title：Human pathology

authors： Wang NS,Seemayer TA,Ahmed MN,Knaack J

更新日期：1976-01-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a commonly occurring tumor in southern China. Although several causative factors have now been recognized, the genetic basis underlying its tumorigenesis is still unclear. To identify potential chromosomal aberrations for further investigations, comparative genomic hybridization (CGH)...

journal_title：Human pathology

authors： Fan CS,Wong N,Leung SF,To KF,Lo KW,Lee SW,Mok TS,Johnson PJ,Huang DP

更新日期：2000-02-01 00:00:00

abstract：:A digoxigenin-tailed, synthetic oligodeoxynucleotide was used to detect genomic hepatitis delta virus (HDV) RNA in formalin-fixed, paraffin-embedded liver sections by a nonisotopic in situ hybridization (NISH) procedure. Twenty-three liver samples from chronically HDV-infected patients were studied. Eight liver specim...

journal_title：Human pathology

authors： Pacchioni D,Negro F,Chiaberge E,Rizzetto M,Bonino F,Bussolati G

更新日期：1992-05-01 00:00:00

abstract：:Posttransplant lymphoproliferative disorder (PTLD) is associated with Epstein-Barr virus (EBV), and may clinically resemble acute allograft rejection. Three methods to show EBV in tissue were evaluated in 15 liver allograft biopsies from 12 patients including four with PTLD: (1) semiquantitative polymerase chain react...

journal_title：Human pathology

authors： Lones MA,Shintaku IP,Weiss LM,Thung SN,Nichols WS,Geller SA

更新日期：1997-05-01 00:00:00

abstract：:α-Thalassemia/mental retardation syndrome X-linked protein (ATRX) and death domain-associated protein (DAXX) genes are tumor suppressors whose mutations have been identified in sporadic pancreatic neuroendocrine tumors as well as in patients with MEN1. However, it is unknown whether ATRX and DAXX alterations are speci...

journal_title：Human pathology

authors： Chen SF,Kasajima A,Yazdani S,Chan MS,Wang L,He YY,Gao HW,Sasano H

更新日期：2013-10-01 00:00:00

abstract：:Improved graft survival was observed in cadaver-kidney recipients prepared with random donor blood transfusions and in selected living-related-kidney recipients primed with transfusions from the kidney donor. This seems to justify a purposeful transfusion policy in these patients. ...

journal_title：Human pathology

authors： Polesky HF,Lasky LC

更新日期：1983-03-01 00:00:00

abstract：:Viruses and other possible causative agents should be sought light and electron microscopically in all cases of ill-defined diseases including "sarcoid." Ideally, tissue should be prepared for electron microscopic examination as soon as a specimen is obtained; however, when this has not been done, tissue preserved in ...

journal_title：Human pathology

authors： Wang NS

更新日期：1983-10-01 00:00:00

abstract：:Among 236 aortic valves surgically excised at the Mayo Clinic in 1990 (mean patient age, 66 years; age range, 10 to 92 years), 154 (65%) were stenotic, 58 (25%) were insufficient, and 24 (10%) were both stenotic and insufficient. Pure stenosis was related to calcification, and causes included degenerative (51%), bicus...

journal_title：Human pathology

authors： Dare AJ,Veinot JP,Edwards WD,Tazelaar HD,Schaff HV

更新日期：1993-12-01 00:00:00

abstract：:Disheveled-axin (DIX) domain containing 1 (DIXDC1), a protein containing a coiled-coil domain and a DIX domain, is involved in the progression of multiple cancers. However, the role of DIXDC1 in human pancreatic ductal adenocarcinoma (PDAC) remains unclear. In this study, we investigated the role and prognostic value ...

journal_title：Human pathology

authors： Li X,Xiao Y,Fan S,Xiao M,Wang X,Zhu X,Chen X,Li C,Zong G,Zhou G,Wan C

更新日期：2016-11-01 00:00:00

abstract：:Merkel cell polyomavirus is of oncogenic significance in approximately 80% of Merkel cell carcinomas. Morphological subcategories of the tumor differ in regard to viral status, the rare combined type being uniformly virus negative and the predominant pure type being mainly virus positive. Indications that different bi...

journal_title：Human pathology

authors： Lai JH,Fleming KE,Ly TY,Pasternak S,Godlewski M,Doucette S,Walsh NM

更新日期：2015-09-01 00:00:00

abstract：:Immunofluorescent staining of tissue from a lung tumor detected 12 years after excision of a primary malignant melanoma of the skin was negative for prekeratin and positive for vimentin, indicating that the tumor was not epithelial in origin and excluding carcinoma from the differential diagnosis. Complementary conven...

journal_title：Human pathology

authors： Huszar M,Halkin H,Herczeg E,Bubis J,Geiger B

更新日期：1983-11-01 00:00:00

abstract：:Four different genetic abnormalities may occur in endometrioid adenocarcinomas of the endometrium (mircosatellite instability and mutations in the PTEN, k-RAS and beta-catenin genes), whereas nonendometrioid carcinomas of the endometrium often have p53 mutations and loss of heterozygosity on several chromosomes. Occas...

journal_title：Human pathology

authors： Matias-Guiu X,Catasus L,Bussaglia E,Lagarda H,Garcia A,Pons C,Muñoz J,Argüelles R,Machin P,Prat J

更新日期：2001-06-01 00:00:00

abstract：:Reactive bone marrow mast cells reliably lack the morphologic, immunophenotypic, and molecular features of systemic mastocytosis (SM). We report two unusual cases of acquired aplastic anemia (AA) in which multifocal aggregates of bone marrow mast cells fulfilled morphologic and immunophenotypic criteria for SM accordi...

journal_title：Human pathology

authors： Golardi N,Sramek JE,Myers JB,Saffer H,George TI,Czuchlewski DR

更新日期：2014-02-01 00:00:00

abstract：:PELP1 is a novel coregulator of nuclear hormone receptors and is implicated in playing a role in driving breast cancer and enhancing metastatic potential. The PELP1 protein expression and potential role of PELP1 in triple-negative breast carcinoma (TNBC) have not been well characterized. We investigated PELP1 expressi...

journal_title：Human pathology

authors： Dang DN,Raj G,Sarode V,Molberg KH,Vadlamudi RK,Peng Y

更新日期：2015-12-01 00:00:00

abstract：:Heavy proteinuria after bone marrow transplantation (BMT) is rare. Pathology shows membranous glomerulonephritis (MGN) in most cases. After BMT, focal segmental glomerulosclerosis (FSGS) after resolution of MGN has not been reported. We describe a 13-year-old boy who had matched unrelated donor allogeneic BMT for rela...

journal_title：Human pathology

authors： Chan GS,Chim S,Fan YS,Chan KW

更新日期：2006-12-01 00:00:00

abstract：:The immunohistochemical expression of cell adhesion molecules in colorectal serrated adenocarcinoma is still unknown. The immunostaining patterns of β-catenin, E-cadherin, P-cadherin, laminin 5γ2, and SMAD4 and their relationship to survival were studied in different tumor areas, namely, tumor center and invasive fron...

journal_title：Human pathology

authors： García-Solano J,Conesa-Zamora P,Trujillo-Santos J,Torres-Moreno D,Mäkinen MJ,Pérez-Guillermo M

更新日期：2012-07-01 00:00:00

abstract：:Sixteen cases of intermediate lymphocytic lymphoma (ILL), including eight cases with mantle zone architecture, were studied using cryostat sections, a biotin-avidin immunoperoxidase technique, and a large panel of monoclonal antibodies. The neoplastic cells invariably expressed IgM, most B lineage antigens (B1, TO15, ...

journal_title：Human pathology

authors： Strickler JG,Medeiros LJ,Copenhaver CM,Weiss LM,Warnke RA

更新日期：1988-05-01 00:00:00

abstract：:Although adipophilin has been reported to be a sensitive marker for sebaceous carcinoma, others have noted its expression in squamous cell carcinoma and a variety of noncutaneous tumors, suggesting that lipid droplet accumulation is a frequent feature of neoplastic cells. We investigated the expression of adipophilin ...

journal_title：Human pathology

authors： Boussahmain C,Mochel MC,Hoang MP

更新日期：2013-09-01 00:00:00