A rosette-forming glioneuronal tumor of the spinal cord: the first case of a rosette-forming glioneuronal tumor originating from the spinal cord.

Abstract:

:Rosette-forming glioneuronal tumors of the fourth ventricle are rare brain tumors, and only 19 such lesions have been previously reported. This report presents the first case of a rosette-forming glioneuronal tumors arising from the spinal cord. A 44-year-old woman presented with a 15-year history of dissociated sensory disturbance of the lower extremities that gradually spread through her upper extremities. She also experienced continuing motor disturbance. Magnetic resonance imaging demonstrated a mass in the cervicothoracic spinal cord that suggested an intramedullary spinal tumor. A total gross resection of the tumor was performed. As is typical of rosette-forming glioneuronal tumors of the fourth ventricle, this spinal cord example manifested neurocytic and astrocytic components. Neurocytic rosettes were detected in the neurocytic component, and the center of rosettes showed positive immunostaining for synaptophysin. The astrocytic component showed characteristic features of a pilocytic astrocytoma, as is often the case in the fourth ventricle examples.

journal_name

Hum Pathol

journal_title

Human pathology

authors

Anan M,Inoue R,Ishii K,Abe T,Fujiki M,Kobayashi H,Goya T,Nakazato Y

doi

10.1016/j.humpath.2008.11.010

subject

Has Abstract

pub_date

2009-06-01 00:00:00

pages

898-901

issue

6

eissn

0046-8177

issn

1532-8392

pii

S0046-8177(08)00568-6

journal_volume

40

pub_type

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