Structured electronic template for histopathology reports on colorectal carcinomas: a joint project by the Cancer Registry of Norway and the Norwegian Society for Pathology.


:Both individual patient treatment and cancer registries depend on adequate histopathology reports. To ensure the quality of these reports, professional organizations have published guidelines on minimum data sets for various cancer types. Norway has a population of 4.6 million, and all individuals have a unique identification number. As required by law, relevant information on cancer is submitted to the Cancer Registry of Norway. A closed, national health data network has been established facilitating electronic transferal between various institutions. The Cancer Registry and the Norwegian Society for Pathology have jointly established a nationwide project to (i) develop standardized templates in database format for histopathology reports on cancer resection specimens and (ii) develop an Extensible Markup Language (XML) standard to facilitate future electronic transfer of cancer reports from hospitals to the Cancer Registry. A minimum data set template for reporting colorectal carcinoma resection specimens and the Extensible Markup Language standard have been established. The template is based on international guidelines and classification systems. For most key parameters, pull-down menus with predefined alternatives have been constructed. The template is fully integrated into software being used by all pathology laboratories in Norway. Since the introduction of the template in April 2005, the template had been used for reporting 430 (93%) of 462 colorectal resections at 2 pilot laboratories (Akershus University Hospital [Lørenskog, Norway] and Stavanger, University Hospital [Stavanger, Norway]), demonstrating that high and consistent quality can be ascertained. Pathologists have found the template both time saving and user friendly. The template is now gradually implemented nationwide.


Hum Pathol


Human pathology


Bjugn R,Casati B,Norstein J




Has Abstract


2008-03-01 00:00:00














  • Neuropathology of the spinal cord in the acquired immunodeficiency syndrome.

    abstract::The neuropathologic findings in the spinal cord were reviewed in 138 consecutive autopsies of patients with the acquired immunodeficiency syndrome. In all cases both the brain and spinal cord were examined by conventional histologic techniques, and in 63 cases immunohistochemistry was used to detect human immunodefici...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Hénin D,Smith TW,De Girolami U,Sughayer M,Hauw JJ

    更新日期:1992-10-01 00:00:00

  • Clinicopathologic significance of DNA methyltransferase 1, 3a, and 3b overexpression in Tunisian breast cancers.

    abstract::DNA methyltransferase 1, 3a, and 3b affect DNA methylation, and it is thought that they play an important role in the malignant transformation of various cancers. The current study was designed to analyze DNA methyltransferase expression by immunohistochemistry in a series of 94 Tunisian sporadic breast carcinomas. Re...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Ben Gacem R,Hachana M,Ziadi S,Ben Abdelkarim S,Hidar S,Trimeche M

    更新日期:2012-10-01 00:00:00

  • Reduced expression of syndecan-1 correlates with histologic dedifferentiation, lymph node metastasis, and poor prognosis in intrahepatic cholangiocarcinoma.

    abstract::Syndecan-1, a cell-surface transmembrane heparan sulfate proteoglycan, has been reported to correlate with the biologic behavior of malignant tumors in various organs. We examined the correlation between the expression of syndecan-1 at the protein and mRNA levels and clinicopathologic features of 37 intrahepatic chola...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Harada K,Masuda S,Hirano M,Nakanuma Y

    更新日期:2003-09-01 00:00:00

  • Virus-associated hemophagocytic syndrome: identification of an immunoproliferative precursor lesion.

    abstract::Virus-associated hemophagocytic syndrome (VAHS) is a nonneoplastic, generalized histiocytic proliferation with marked hemophagocytosis associated with a systemic viral infection. Histologic studies of lymph nodes usually show lymphoid depletion and histiocytic proliferation. In this report we describe the case of a pa...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Daum GS,Sullivan JL,Ansell J,Mulder C,Woda BA

    更新日期:1987-10-01 00:00:00

  • Use of remote video microscopy (telepathology) as an adjunct to neurosurgical frozen section consultation.

    abstract::We investigated the use of remote video microscopy (telepathology) to assist in the diagnosis of 52 neurosurgical frozen section cases. The TelMed system (Discovery Medical Systems, Overland Park, KS), in which the referring pathologist selects appropriate fields for transmission to the consultant, was used for the st...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Becker RL Jr,Specht CS,Jones R,Rueda-Pedraza ME,O'Leary TJ

    更新日期:1993-08-01 00:00:00

  • Telomere lengths differ significantly between small-cell neuroendocrine prostate carcinoma and adenocarcinoma of the prostate.

    abstract::Small-cell neuroendocrine carcinoma (SCNC) of the prostate is an aggressive subtype with frequent TP53 mutation and RB1 inactivation; however, the molecular phenotype remains an area of investigation. Here, we compared telomere lengths in prostatic SCNC and usual-type prostatic adenocarcinoma (AdCa). We studied 32 cas...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Heaphy CM,Haffner MC,Graham MK,Lim D,Davis C,Corey E,Epstein JI,Eisenberger MA,Wang H,De Marzo AM,Meeker AK,Lotan TL

    更新日期:2020-07-01 00:00:00

  • Epithelial-to-mesenchymal transition-related transcription factors are up-regulated in ependymomas and correlate with a poor prognosis.

    abstract::Epithelial-to-mesenchymal transition (EMT) plays an important role in invasion and metastasis of various cancers including gliomas. EMT has also been linked to cancer stem cells and resistance to chemotherapy. An initial in-silico data mining in a published ependymoma (EPN) patient series (GSE21687) revealed up-regula...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Malgulwar PB,Nambirajan A,Pathak P,Rajeshwari M,Suri V,Sarkar C,Singh M,Sharma MC

    更新日期:2018-12-01 00:00:00

  • Cardiomyopathy and myocyte intranuclear inclusions in neuronal intranuclear inclusion disease: a case report.

    abstract::Neuronal intranuclear inclusion disease (NIID) is a progressive, usually fatal degenerative neurologic condition characterized by eosinophilic, intranuclear inclusions in neurons of the central and peripheral nervous system. We report a boy with onset of disease manifestations at age 3 and death at age 9, who showed c...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Oyer CE,Cortez S,O'Shea P,Popovic M

    更新日期:1991-07-01 00:00:00

  • MicroRNAs in Ovarian Cancer.

    abstract::Ovarian cancer, consisting predominantly of ovarian carcinoma, is the eighth most common cancer in women and the most lethal gynecologic malignancy. Efforts focus on identifying biomarkers which may aid in early diagnosis and reduce mortality, as well as on characterizing therapeutic targets with the aim of circumvent...

    journal_title:Human pathology

    pub_type: 杂志文章,评审


    authors: Katz B,Tropé CG,Reich R,Davidson B

    更新日期:2015-09-01 00:00:00

  • Cutaneous manifestations in patients with coronavirus disease 2019: clinical and histological findings.

    abstract::The clinical spectrum of coronavirus disease 2019 is getting wider with the exponential increase of patients worldwide. Initially described with flu-like symptoms, variable cutaneous manifestations have been reported, with only few histopathological descriptions. Detection of the virus in cutaneous samples has been as...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Fattori A,Cribier B,Chenard MP,Mitcov M,Mayeur S,Weingertner N

    更新日期:2021-01-01 00:00:00

  • Endocardial fibroelastosis and myocardial calcification secondary to an anomalous right coronary artery arising from the pulmonary trunk.

    abstract::The case of an infant with endocardial fibroelastosis and a coexistent anomalous right coronary artery that originated from the pulmonary trunk is presented. The causal relation between the two conditions is discussed. ...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Huang TY,Hsueh Y,Tsung SH

    更新日期:1985-09-01 00:00:00

  • Incidence of loss of heterozygosity at p53 and BRCA1 loci in serous surface carcinoma.

    abstract::Serous surface carcinoma (SSC) is a neoplasm histologically indistinguishable from typical serous carcinomas that arise from the ovary but has a distinct clinical presentation. It is characterized by widespread peritoneal dissemination at presentation, but the ovaries are grossly normal in size and shape. If the carci...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Quezado MM,Moskaluk CA,Bryant B,Mills SE,Merino MJ

    更新日期:1999-02-01 00:00:00

  • Overexpression of the chemokine receptor CXCR3 and its correlation with favorable prognosis in gastric cancer.

    abstract::Chemokine receptor, CXCR3, has been increasingly reported to be involved in tumorigenesis and tumor progression, but limited data are available regarding the expression of CXCR3 in gastric cancer (GC). In the present study, the expressions of CXCR3 and its variants were detected in 96 GC and corresponding nontumor gas...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Hu M,Li K,Maskey N,Xu Z,Yu F,Peng C,Li Y,Yang G

    更新日期:2015-12-01 00:00:00

  • Dysplasia and early carcinoma in inflammatory bowel disease and colorectal adenomas.

    abstract::The control of colorectal cancer is currently dependent on early detection, and its prevention requires the recognition and treatment of its precursor lesions. The adenoma has been established as the precursor of colorectal carcinoma in the general population. Among patients with inflammatory bowel disease (IBD), dysp...

    journal_title:Human pathology

    pub_type: 杂志文章,评审


    authors: Pascal RR

    更新日期:1994-11-01 00:00:00

  • Expression of the RNA component of telomerase in Wilms tumor and nephrogenic rest recapitulates renal embryogenesis.

    abstract::Telomerase is a ribonucleoprotein enzyme associated with cellular immortality and has been detected in the vast majority of adult tumors. Wilms tumor is a histologically diverse embryonal malignancy of childhood, and the histological features of Wilms tumor and its precursor lesion, the nephrogenic rest, recapitulate ...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Yashima K,Maitra A,Timmons CF,Rogers BB,Pinar H,Shay JW,Gazdar AF

    更新日期:1998-05-01 00:00:00

  • Disseminated infection with Lacazia loboi and immunopathology of the lesional spectrum.

    abstract::The pathogenesis of lacaziosis continues to be obscure, and works have investigated the blood systemic immune response or the dermal immune response in restricted lesions in different body regions. Some authors describe that the inflammatory infiltrate in lacaziosis lesions showed a predominance of macrophages followe...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Oliveira Carneiro FR,da Cunha Fischer TR,Brandão CM,Pagliari C,Duarte MI,Quaresma JA

    更新日期:2015-02-01 00:00:00

  • Characterization of human Rab20 overexpressed in exocrine pancreatic carcinoma.

    abstract::In a large-scale analysis of gene expression in pancreatic cancer, we isolated the homologue of the mouse Rab20. The mouse protein was previously identified during a search for novel Rab proteins, a family of small GTP-binding proteins involved in the regulation of intracellular vesicular transport. The Rab20 protein ...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Amillet JM,Ferbus D,Real FX,Antony C,Muleris M,Gress TM,Goubin G

    更新日期:2006-03-01 00:00:00

  • Focal adhesion proteins as markers of malignant transformation and prognostic indicators in breast carcinoma.

    abstract::Focal adhesion kinase (FAK) is one of the central signaling molecules found at focal adhesion sites, which are specific areas on the cell membrane where cells attach to extracellular matrix proteins. Focal adhesion kinase interacts with multiple signaling and adaptor molecules and effects several signaling pathways. O...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Madan R,Smolkin MB,Cocker R,Fayyad R,Oktay MH

    更新日期:2006-01-01 00:00:00

  • Diffuse and localized tenosynovial giant cell tumor and pigmented villonodular synovitis: a clinicopathologic and flow cytometric DNA analysis.

    abstract::The DNA content and proliferative indexes of seven cases of tenosynovial giant cell tumor of tendon sheath, diffuse type (TGCT-D); 11 cases of tenosynovial giant cell tumor of tendon sheath, localized type (TGCT-L); and seven cases of pigmented villonodular synovitis (PVNS) were analyzed by flow cytometry in an attemp...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Abdul-Karim FW,el-Naggar AK,Joyce MJ,Makley JT,Carter JR

    更新日期:1992-07-01 00:00:00

  • Silicone lymphadenopathy: a complication of silicone elastomer finger joint prostheses.

    abstract::Two cases of lymphadenopathy resulting from a lymph node foreign body reaction to silicone are presented. In each case lymph node biopsy was performed because of the clinical suspicion of neoplastic disease. Histologic study in both cases revealed no evidence of malignant disease, but rather demonstrated multinucleate...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Kircher T

    更新日期:1980-05-01 00:00:00

  • Paragangliomas of the head and neck region. A pathologic study of tumors from 71 patients.

    abstract::The histopathology of 72 paragangliomas originating in the head and neck region of 71 patients is presented. There were 45 carotid body, 13 vagal body, eight jugulotympanic, and three nasal paragangliomas. In addition, two arose in the larynx and one in the area of the aortic arch. Tumors occurred in four unrelated fa...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Lack EE,Cubilla AL,Woodruff JM

    更新日期:1979-03-01 00:00:00

  • Papillary renal cell carcinoma with oncocytic cells and nonoverlapping low grade nuclei: expanding the morphologic spectrum with emphasis on clinicopathologic, immunohistochemical and molecular features.

    abstract::Papillary renal cell carcinoma (PRCC), a morphologically and genetically distinct subtype of RCC, is morphologically separated into 2 subtypes, type 1 and 2, for prognostic purposes. Type 1 PRCC (single layer of small cells, scant pale cytoplasm) is more common and has a favorable prognosis compared with type 2 (pseud...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Kunju LP,Wojno K,Wolf JS Jr,Cheng L,Shah RB

    更新日期:2008-01-01 00:00:00

  • Claudin-4 shows superior specificity for mesothelioma vs non-small-cell lung carcinoma compared with MOC-31 and Ber-EP4.

    abstract::The distinction of malignant mesothelioma from non-small-cell lung carcinoma (NSCLC) usually requires immunohistochemistry, but some broad-spectrum carcinoma markers stain mesotheliomas, and it remains unclear which broad-spectrum markers are most valuable for distinguishing these malignancies. Here, we directly compa...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Naso JR,Churg A

    更新日期:2020-06-01 00:00:00

  • Detection of hepatitis B virus DNA in paraffin-embedded intrahepatic and extrahepatic cholangiocarcinoma tissue in the northern Chinese population.

    abstract::This study explored the importance of hepatitis B virus infection in cholangiocarcinoma pathogenesis in northern China. The clinical data of 66 patients with cholangiocarcinoma were analyzed. The hepatitis B virus gene was amplified using nested polymerase chain reaction, and the hepatitis B virus-related antigen was ...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Wu Y,Wang T,Ye S,Zhao R,Bai X,Wu Y,Abe K,Jin X

    更新日期:2012-01-01 00:00:00

  • Identification of prekeratin by immunofluorescence staining in the differential diagnosis of tumors.

    abstract::Fibrillar proteins with a role in cellular shape and motility are present in the cytoplasm of most animal cells. They vary greatly in size, organization, and reactivity according to cell type and can be separately identified by the use of recently developed monospecific antisera and indirect immunofluorescence stainin...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Sieinski W,Dorsett B,Ioachim HL

    更新日期:1981-05-01 00:00:00

  • Giant cell pneumonia associated with parainfluenza virus type 3 infection.

    abstract::Giant cell pneumonia associated with parainfluenza virus type 3 infection and chronic poliovirus type 2 meningoencephalomyelitis are documented in an infant with combined immunologic deficiency (Swiss type). Caution should be exercised in attributing cases of giant cell pneumonia to measles virus without serologic or ...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Little BW,Tihen WS,Dickerman JD,Craighead JE

    更新日期:1981-05-01 00:00:00

  • Pathology of cryptococcal meningoencephalitis: analysis of 27 patients with pathogenetic implications.

    abstract::In this autopsy series of cryptococcal meningoencephalitis (CME), the authors analyzed neuropathologic lesions in 13 human immunodeficiency virus (HIV) and 14 non-HIV-related cases. Most non-HIV patients did not have immunosuppressive predisposing illness. Analysis of pathological findings revealed significant differe...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Lee SC,Dickson DW,Casadevall A

    更新日期:1996-08-01 00:00:00

  • Prolactin presents in all pituitary tumors of acromegalic patients.

    abstract::Twenty-two consecutive cases of adenoma in acromegalic patients were studied immunohistochemically. All the tumors contained prolactin (PRL)-reactive cells (3% to 53% of the total number of tumor cells) as well as growth hormone (GH)-reactive cells (4% to 74% of the total number of tumor cells). All acromegalic cases ...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Furuhata S,Kameya T,Otani M,Toya S

    更新日期:1993-01-01 00:00:00

  • Loss of heterozygosity on chromosome 11q13 in lobular lesions of the breast using tissue microdissection and polymerase chain reaction.

    abstract::Demonstration of identical allelic loss on chromosome 11q13 in synchronous in situ (DCIS) and invasive ductal (IDC) breast carcinoma has provided molecular evidence of the progression of DCIS to IDC. We investigated loss of heterozygosity (LOH) at chromosome 11q13 in the spectrum of "marker/premalignant" and "malignan...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Nayar R,Zhuang Z,Merino MJ,Silverberg SG

    更新日期:1997-03-01 00:00:00

  • Scanning electron microscopy, x-ray diffraction, and electron microprobe analysis of calcific deposits on intrauterine contraceptive devices.

    abstract::Deposits found intrauterine contraceptive devices (IUDs) were studied by scanning electron microscopy, x-ray diffraction, and energy dispersive x-ray microanalysis. All seven devices, including five plastic and two copper IUDs, were coated with a crust containing cellular, acellular, and fibrillar material. The cellul...

    journal_title:Human pathology

    pub_type: 杂志文章


    authors: Khan SR,Wilkinson EJ

    更新日期:1985-07-01 00:00:00