Structured electronic template for histopathology reports on colorectal carcinomas: a joint project by the Cancer Registry of Norway and the Norwegian Society for Pathology.

abstract：:Thirty cases of ductal carcinoma in situ (DCIS) of the breast, showing histological microcalcifications, were studied to clarify their mechanism of formation. Undecalcified sections revealed three types of calcium precipitates: type I and II granular calcifications (GCs) and laminar calcifications (LCs). In type I GCs...

journal_title：Human pathology

authors： Foschini MP,Fornelli A,Peterse JL,Mignani S,Eusebi V

更新日期：1996-02-01 00:00:00

abstract：:Glial tumors of the retina are rare. Most are syndrome associated and include pilocytic astrocytoma in neurofibromatosis type 1 and subependymal giant cell astrocytoma in tuberous sclerosis complex. Acquired, more conventional, diffuse astrocytomas are less frequent. Ependymoma is exquisitely rare. Herein, we report t...

journal_title：Human pathology

authors： Tay A,Scheithauer BW,Cameron JD,Myhre MJ,Boerner MJ

更新日期：2009-04-01 00:00:00

abstract：:Sex-determining region Y-box 2 is proposed to be a key transcription factor in embryonic stem cells. The known roles of sex-determining region Y-box 2 in development and cell differentiation suggest that it is relevant to the aberrant growth of tumor cells. Thus, sex-determining region Y-box 2 may play an important ro...

journal_title：Human pathology

authors： Zhang J,Chang DY,Mercado-Uribe I,Liu J

更新日期：2012-09-01 00:00:00

abstract：:Neutrophilic dermatoses are an uncommon manifestation of lupus. We describe the clinical and histopathologic features of 14 patients with systemic lupus erythematosus (SLE) and neutrophilic dermatoses, 2 of whom had no prior history of SLE. Thirteen patients were female, ranging in age from 27 to 62 years (mean age, 4...

journal_title：Human pathology

authors： Larson AR,Granter SR

更新日期：2014-03-01 00:00:00

abstract：:The clinical spectrum of coronavirus disease 2019 is getting wider with the exponential increase of patients worldwide. Initially described with flu-like symptoms, variable cutaneous manifestations have been reported, with only few histopathological descriptions. Detection of the virus in cutaneous samples has been as...

journal_title：Human pathology

authors： Fattori A,Cribier B,Chenard MP,Mitcov M,Mayeur S,Weingertner N

更新日期：2021-01-01 00:00:00

abstract：:The epicardium contributes to cardiac formation, particularly during embryogenesis. It remains to be seen if it is also involved in postnatal myocardial homeostasis. This study evaluates the topographic distribution of stem cells (c-Kit) and extracardiac progenitor cells (CXCR4+) and their contribution to ventricular ...

journal_title：Human pathology

authors： Castellani C,Padalino M,China P,Fedrigo M,Frescura C,Milanesi O,Stellin G,Thiene G,Angelini A

更新日期：2010-11-01 00:00:00

abstract：:Microsatellite instability (MSI) defines a specific type of genetic instability. Although consensus diagnostic criteria for MSI definition in colorectal cancer have been established, their utility in other tumor types remain to be proven. Previously we developed a mathematical model for MSI definition in colorectal ca...

journal_title：Human pathology

authors： Musulén E,Moreno V,Reyes G,Sancho FJ,Peinado MA,Esteller M,Herman JG,Combalia N,Rey M,Capellá G

更新日期：2004-03-01 00:00:00

abstract：:Cystic hygroma of the neck was observed in seven spontaneously aborted, severely autolyzed female fetuses. Four of five karyotyped cases had the 45,XO karyotype; one was a normal female, 46,XX. Diagnostic features associated with monosomy X in fetuses, which were observed in six of these cases, include large cystic hy...

journal_title：Human pathology

authors： Byrne J,Blanc WA,Warburton D,Wigger J

更新日期：1984-01-01 00:00:00

abstract：:The Sydney classification for gastritis provides guidelines for histological grading of gastric biopsies. In an ongoing study of gastric preneoplastic lesions in Chiapas, Mexico, 7 biopsies from 150 patients (4 from the antrum and 3 from the body) were obtained during endoscopy and studied histologically. The first 74...

journal_title：Human pathology

authors： Guarner J,Herrera-Goepfert R,Mohar A,Sanchez L,Halperin D,Ley C,Parsonnet J

更新日期：1999-12-01 00:00:00

abstract：:Perineural invasion is a histologic feature usually diagnostic of invasion in malignancies. In the breast, however, it has been associated with benign lesions such as sclerosing adenosis (SA), complex sclerosing lesion/radial scar (CSL/RS), and ductal carcinoma in situ (DCIS). This article describes perineural invasio...

journal_title：Human pathology

authors： Gobbi H,Jensen RA,Simpson JF,Olson SJ,Page DL

更新日期：2001-08-01 00:00:00

abstract：:CD44 is an integral membrane glycoprotein that is a principal receptor for hyaluronan and plays a role in cell-extracellular matrix interactions. Recent studies of melanomas in mouse models have suggested that increased CD44 expression by these tumors may relate to metastatic potential. Immunohistochemical expression ...

journal_title：Human pathology

authors： Leigh CJ,Palechek PL,Knutson JR,McCarthy JB,Cohen MB,Argenyi ZB

更新日期：1996-12-01 00:00:00

abstract：:The histologic classification of pulmonary neoplasms can have important implications regarding appropriate management of patients. Although the histologic classification of lung tumors is predominantly based on morphology, ancillary studies such as immunohistochemistry can be used in difficult cases, and the diagnosis...

journal_title：Human pathology

authors： Lyda MH,Weiss LM

更新日期：2000-08-01 00:00:00

abstract：:Recent studies have indicated that some cases of fulminant hepatitis that were ostensibly type B were actually acute viral hepatitis, types B and delta, or persistent hepatitis, type B with superimposed acute delta infection. Histologic characterization of the various types has not yet been undertaken. Within ten to 3...

journal_title：Human pathology

authors： Govindarajan S,de Cock KM,Peters RL

更新日期：1985-03-01 00:00:00

abstract：:Twenty-two consecutive cases of adenoma in acromegalic patients were studied immunohistochemically. All the tumors contained prolactin (PRL)-reactive cells (3% to 53% of the total number of tumor cells) as well as growth hormone (GH)-reactive cells (4% to 74% of the total number of tumor cells). All acromegalic cases ...

journal_title：Human pathology

authors： Furuhata S,Kameya T,Otani M,Toya S

更新日期：1993-01-01 00:00:00

abstract：:We report four unusual cases of hyalinizing trabecular thyroid tumors, three of which displayed capsular and/or blood vessel invasion and were classified as minimally invasive carcinomas. These three patients were all euthyroid women aged 18, 39, and 62 years. The youngest patient also had familial polyposis, while th...

journal_title：Human pathology

authors： Molberg K,Albores-Saavedra J

更新日期：1994-02-01 00:00:00

abstract：:In retinoblastoma, genetic alteration of N-myc amplification different from the alteration of the RB1 gene on chromosome 13q14 has been described. This study is to determine the frequency of N-myc amplification by fluorescence in situ hybridization method in retinoblastoma. This study was prospectively derived from 26...

journal_title：Human pathology

authors： Kim JH,Choi JM,Yu YS,Kim DH,Kim JH,Kim KW

更新日期：2008-08-01 00:00:00

abstract：:Recently, a polymorphism in the hMSH2 DNA mismatch repair gene has been associated with the development of dysplasia in ulcerative colitis (UC) patients. This polymorphism is of interest because DNA mismatch repair defects result in alterations in microsatellite stability. The current study was designed to determine w...

journal_title：Human pathology

authors： Noffsinger AE,Belli JM,Fogt F,Fischer J,Goldman H,Fenoglio-Preiser CM

更新日期：1999-01-01 00:00:00

abstract：:Secretory carcinoma (SC) of the salivary gland is a low-grade malignancy associated with a well-defined clinical, histologic, immunohistochemical, and cytogenetic signature. Although the t(12;15) (p13;q25) translocation resulting in an ETV6-NTRK3 gene fusion is well documented, advances in molecular profiling in saliv...

journal_title：Human pathology

authors： Guilmette J,Dias-Santagata D,Nosé V,Lennerz JK,Sadow PM

更新日期：2019-01-01 00:00:00

abstract：:Small-cell neuroendocrine carcinoma (SCNC) of the prostate is an aggressive subtype with frequent TP53 mutation and RB1 inactivation; however, the molecular phenotype remains an area of investigation. Here, we compared telomere lengths in prostatic SCNC and usual-type prostatic adenocarcinoma (AdCa). We studied 32 cas...

journal_title：Human pathology

authors： Heaphy CM,Haffner MC,Graham MK,Lim D,Davis C,Corey E,Epstein JI,Eisenberger MA,Wang H,De Marzo AM,Meeker AK,Lotan TL

更新日期：2020-07-01 00:00:00

abstract：:Congenital cystic airway malformation/congenital pulmonary airway malformation (CCAM/CPAM) of the lung is a rare but well-described malformative lesion of pulmonary parenchyma characterized by the abnormal maturation of airways along with an increase in terminal respiratory structures, resulting in cysts of variable s...

journal_title：Human pathology

authors： Guo H,Cajaiba MM,Borys D,Gutierrez MC,Yee H,Drut RM,Drut R,Askin F,Reyes-Múgica M,Greco MA

更新日期：2007-12-01 00:00:00

abstract：:Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) generally confers poor prognosis; however, the clinical outcome remains heterogeneous. We sought to further stratify this subentity of AML by performing a retrospective analysis of 179 adult patients with AML-MRC diagnosed at our institution. Based o...

journal_title：Human pathology

authors： Jiang G,Capo-Chichi JM,Liu A,Atenafu EG,Guo R,Tierens A,Minden MD,Chang H

更新日期：2020-10-01 00:00:00

abstract：:Trefoil factors are wound-healing peptides important in protection and healing of the human gastrointestinal tract. Their potential for therapy of gastrointestinal ulcers has been established. This study investigated the hypothesis that trefoil factors are also present in human salivary gland. Tissues from surgical bi...

journal_title：Human pathology

authors： Devine DA,High AS,Owen PJ,Poulsom R,Bonass WA

更新日期：2000-04-01 00:00:00

abstract：:Ki-67 proliferative index (Ki-67 index) is suggested to be an important prognostic variable and is included as one of the grading parameters for neuroendocrine tumors. The present study was undertaken to determine the usefulness of the Ki-67 index and the corresponding tumor grade in predicting progression-free surviv...

journal_title：Human pathology

authors： Dhall D,Mertens R,Bresee C,Parakh R,Wang HL,Li M,Dhall G,Colquhoun SD,Ines D,Chung F,Yu R,Nissen NN,Wolin E

更新日期：2012-04-01 00:00:00

abstract：:We present a rare case of unilateral intratesticular cystadenocarcinoma with mucinous differentiation in a 71-year-old male patient. The orchiectomy specimen revealed a 3.5-cm well to moderately differentiated cystic neoplasm with elongated fine papillary structures lined by columnar epithelium with alternating goblet...

journal_title：Human pathology

authors： Iuga AC,Mull J,Batra R,Miller W

更新日期：2011-09-01 00:00:00

abstract：:A large mass in the right orbit, causing proptosis, ptosis of the right upper eyelid, and limitation to eye movements, was surgically removed from a 51-year-old woman suffering from Paget's bone disease (PBD). Histologically, a giant cell tumor of the bone (osteoclastoma) was diagnosed. No bony involvement was apparen...

journal_title：Human pathology

authors： Pecorella I,Ciardi A,Amadeo G,Baiocchini A,Marasco A,Di Tondo U

更新日期：2000-12-01 00:00:00

abstract：:A unique case of primary papillary hyperplasia of the gallbladder and cystic and common bile ducts occurring in a young female without calculi, ulcerative colitis, or primary sclerosing cholangitis is reported. The papillary lesion involved the mucosa of the entire gallbladder and of the cystic and common bile ducts. ...

journal_title：Human pathology

authors： Albores-Saavedra J,Defortuna SM,Smothermon WE

更新日期：1990-02-01 00:00:00

abstract：:The number of opportunistic infections in the central nervous system (CNS) has been steadily increasing because of a rising number of immunocompromised patients. A rare form of CNS infection can be caused by Chaetomium species, one of the largest genera of saprophytic ascomycetes. The CNS lesions in the present case w...

journal_title：Human pathology

authors： Thomas C,Mileusnic D,Carey RB,Kampert M,Anderson D

更新日期：1999-07-01 00:00:00

abstract：:In a recent evaluation by comparative genomic hybridization, we demonstrated chromosome 14q31-32.1 to be frequently deleted in adenocarcinomas of the gastroesophageal junction. This suggests the presence of a tumor suppressor gene in the deleted region. In the present study, we have performed a detailed loss of hetero...

journal_title：Human pathology

authors： Dinjens WN,Koppert LB,Dezentjé DA,Abbou M,van Ballegooijen ES,Sleddens HF,van Dekken H,Tilanus HW,Wijnhoven BP

更新日期：2006-05-01 00:00:00

abstract：:Although all carcinoid tumors are considered potentially malignant, the biologic behaviors of appendiceal and ileal carcinoids are distinctly different. Appendiceal carcinoids often behave in a benign fashion, whereas ileal carcinoids pursue an aggressive course with frequent metastasis. Whether differences in DNA plo...

journal_title：Human pathology

authors： Goolsby CL,Punyarit P,Mehl PJ,Rao MS

更新日期：1992-12-01 00:00:00

abstract：:The canals of Hering (CoH), converging from the hepatic lobule onto the portal tract, connect bile canaliculi to the interlobular bile ducts, and represent the most proximal portion of the bile drainage pathway with a cholangiocyte lining. In this study we sought to ascertain whether this proximal pathway is involved ...

journal_title：Human pathology

authors： Saxena R,Hytiroglou P,Thung SN,Theise ND

更新日期：2002-10-01 00:00:00