Electron microscopic study of testicular tumor in congenital adrenal hyperplasia.

Abstract:

:Ultrastructural features of bilateral testicular biopsy materials, obtained from both tumor and nontumor areas of the testis of a 27-year-old man with congenital adrenal hyperplasia, revealed a number of pathologic changes. Germ cell hypoplasia and extratubular cellular hyperplasia were noticed in the nontumor portion of the testis. In some areas of the tumor, dense collagenous materials surrounded the compressed degenerative seminiferous tubule. In other areas at least three different types of cells were identified: 1) branched, irregular giant cells, 2) small cells in clusters, and 3) modified myoid or smooth muscle cells. It is suggested that these three types of cells have different origins. The concept that these types of tumor cells originate from "pluripotential cells" is supported.

journal_name

Hum Pathol

journal_title

Human pathology

authors

Chakraborty J,Franco-Saenz R,Kropp K

doi

10.1016/s0046-8177(83)80244-5

subject

Has Abstract

pub_date

1983-02-01 00:00:00

pages

151-7

issue

2

eissn

0046-8177

issn

1532-8392

pii

S0046-8177(83)80244-5

journal_volume

14

pub_type

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